JP2014124186A - 多価抗体フラグメントおよびその三量体化複合体 - Google Patents

多価抗体フラグメントおよびその三量体化複合体 Download PDF

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Publication number
JP2014124186A
JP2014124186A JP2013268028A JP2013268028A JP2014124186A JP 2014124186 A JP2014124186 A JP 2014124186A JP 2013268028 A JP2013268028 A JP 2013268028A JP 2013268028 A JP2013268028 A JP 2013268028A JP 2014124186 A JP2014124186 A JP 2014124186A
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Japan
Prior art keywords
igg
antibody fragment
multivalent antibody
human
antibody
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Pending
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JP2013268028A
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English (en)
Japanese (ja)
Inventor
Min-Yuan Chou
民元 周
Chuan-Chuan Huang
娟娟 黄
Hsiu-Chuan Li
秀娟 李
ya-ping Lai
雅萍 頼
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Industrial Technology Research Institute ITRI
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Industrial Technology Research Institute ITRI
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Priority claimed from US13/761,569 external-priority patent/US10329350B2/en
Application filed by Industrial Technology Research Institute ITRI filed Critical Industrial Technology Research Institute ITRI
Publication of JP2014124186A publication Critical patent/JP2014124186A/ja
Pending legal-status Critical Current

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  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
JP2013268028A 2012-12-26 2013-12-25 多価抗体フラグメントおよびその三量体化複合体 Pending JP2014124186A (ja)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
TW101150029 2012-12-26
TW101150029 2012-12-26
US13/761,569 2013-02-07
US13/761,569 US10329350B2 (en) 2012-12-26 2013-02-07 Method for producing a multivalent fab fragment with collagen-like peptide
TW102136456 2013-10-09
TW102136456A TWI629284B (zh) 2012-12-26 2013-10-09 多價抗體片段與其三聚複合物

Publications (1)

Publication Number Publication Date
JP2014124186A true JP2014124186A (ja) 2014-07-07

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JP2013268028A Pending JP2014124186A (ja) 2012-12-26 2013-12-25 多価抗体フラグメントおよびその三量体化複合体

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JP (1) JP2014124186A (zh)
CN (1) CN103897057B (zh)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017098005A1 (en) * 2015-12-11 2017-06-15 Leadartis, S.L. Single chain fusionconstructs comprising multimeric antibody fragments fused to collagen trimerization domains
WO2021030680A1 (en) * 2019-08-15 2021-02-18 Regeneron Pharmaceuticals, Inc. Multispecific antigen-binding molecules for cell targeting and uses thereof
WO2023227018A1 (zh) * 2022-05-25 2023-11-30 羿尊生物医药（浙江）有限公司 靶向细胞膜受体蛋白的融合蛋白及其应用

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2983034A1 (en) * 2015-04-17 2016-10-20 Igm Biosciences, Inc. Multi-valent human immunodeficiency virus antigen binding molecules and uses thereof
US11180541B2 (en) 2017-09-28 2021-11-23 Geltor, Inc. Recombinant collagen and elastin molecules and uses thereof
TW202104254A (zh) 2019-04-12 2021-02-01 美商格爾托公司 重組彈性蛋白及其生產
WO2021249009A1 (en) * 2020-06-10 2021-12-16 Sichuan Clover Biopharmaceuticals, Inc. Rsv vaccine compositions, methods, and uses thereof

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009131237A (ja) * 2007-11-30 2009-06-18 Ind Technol Res Inst 三量体コラーゲン足場抗体

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10122140A1 (de) * 2001-05-08 2002-11-28 Apotech Res & Dev Ltd Rekombinante Fusionsproteine und deren Trimere
CN1261455C (zh) * 2002-07-19 2006-06-28 余宙耀 一种重组人源性抗乙肝表面抗原（HBsAg）Fab抗体及其制取方法

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009131237A (ja) * 2007-11-30 2009-06-18 Ind Technol Res Inst 三量体コラーゲン足場抗体

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
JPN6015001963; ＦＡＳＥＢ　Ｊ．，　２００８，　Ｖｏｌ．　２２，　Ｎｏ．　１１，　ｐｐ．　３７９５-３８０４ *
JPN6015001966; ＦＥＢＳ　Ｌｅｔｔ．，　１９９４，　Ｖｏｌ．　３４４，　Ｎｏ．　２-３，　ｐｐ．　１９１-１９５ *

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017098005A1 (en) * 2015-12-11 2017-06-15 Leadartis, S.L. Single chain fusionconstructs comprising multimeric antibody fragments fused to collagen trimerization domains
US11306147B2 (en) 2015-12-11 2022-04-19 Leadartis, S.L. Single chain fusionconstructs comprising multimeric antibody fragments fused to collagen trimerization domains
WO2021030680A1 (en) * 2019-08-15 2021-02-18 Regeneron Pharmaceuticals, Inc. Multispecific antigen-binding molecules for cell targeting and uses thereof
US11952430B2 (en) 2019-08-15 2024-04-09 Regeneron Pharmaceuticals, Inc. Multispecific antigen-binding molecules for cell targeting and uses thereof
US12065508B2 (en) 2019-08-15 2024-08-20 Regeneron Pharmaceuticals, Inc. Multispecific antigen-binding molecules for cell targeting and uses thereof
US12077603B2 (en) 2019-08-15 2024-09-03 Regeneron Pharmaceuticals, Inc. Multispecific antigen-binding molecules for cell targeting and uses thereof
WO2023227018A1 (zh) * 2022-05-25 2023-11-30 羿尊生物医药（浙江）有限公司 靶向细胞膜受体蛋白的融合蛋白及其应用

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CN103897057A (zh) 2014-07-02
CN103897057B (zh) 2018-07-13

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