JP2013545728A - 抗菌性ポリエーテルおよびポリオール化合物 - Google Patents

抗菌性ポリエーテルおよびポリオール化合物 Download PDF

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Publication number
JP2013545728A
JP2013545728A JP2013535012A JP2013535012A JP2013545728A JP 2013545728 A JP2013545728 A JP 2013545728A JP 2013535012 A JP2013535012 A JP 2013535012A JP 2013535012 A JP2013535012 A JP 2013535012A JP 2013545728 A JP2013545728 A JP 2013545728A
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JP
Japan
Prior art keywords
mmol
ethoxy
solution
chloro
dichloroamino
Prior art date
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Pending
Application number
JP2013535012A
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English (en)
Japanese (ja)
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JP2013545728A5 (enExample
Inventor
ラケシュ・ケイ・ジャイン
ティモシー・シアウ
チャールズ・フランカビラ
エディ・ロウ
エリック・ダグラス・タートル
ドノー・ジョン・ロジャー・オマホニー
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Novabay Pharmaceuticals Inc
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Novabay Pharmaceuticals Inc
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Publication of JP2013545728A publication Critical patent/JP2013545728A/ja
Publication of JP2013545728A5 publication Critical patent/JP2013545728A5/ja
Pending legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4166—1,3-Diazoles having oxo groups directly attached to the heterocyclic ring, e.g. phenytoin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
    • C07C309/01—Sulfonic acids
    • C07C309/02—Sulfonic acids having sulfo groups bound to acyclic carbon atoms
    • C07C309/03—Sulfonic acids having sulfo groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
    • C07C309/13—Sulfonic acids having sulfo groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton containing nitrogen atoms, not being part of nitro or nitroso groups, bound to the carbon skeleton
    • C07C309/14—Sulfonic acids having sulfo groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton containing nitrogen atoms, not being part of nitro or nitroso groups, bound to the carbon skeleton containing amino groups bound to the carbon skeleton
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N33/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic nitrogen compounds
    • A01N33/02—Amines; Quaternary ammonium compounds
    • A01N33/08—Amines; Quaternary ammonium compounds containing oxygen or sulfur
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/02—Local antiseptics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C239/00—Compounds containing nitrogen-to-halogen bonds; Hydroxylamino compounds or ethers or esters thereof
    • C07C239/02—Compounds containing nitrogen-to-halogen bonds
    • C07C239/04—N-halogenated amines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • C07C317/26—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
    • C07C317/28—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton with sulfone or sulfoxide groups bound to acyclic carbon atoms of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Biochemistry (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Dentistry (AREA)
  • Wood Science & Technology (AREA)
  • Dermatology (AREA)
  • Agronomy & Crop Science (AREA)
  • Pest Control & Pesticides (AREA)
  • Plant Pathology (AREA)
  • Virology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Saccharide Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
JP2013535012A 2010-10-19 2011-10-18 抗菌性ポリエーテルおよびポリオール化合物 Pending JP2013545728A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US39469710P 2010-10-19 2010-10-19
US61/394,697 2010-10-19
US41833410P 2010-11-30 2010-11-30
US61/418,334 2010-11-30
PCT/US2011/056764 WO2012054521A2 (en) 2010-10-19 2011-10-18 Antimicrobial polyether and polyol compounds

Publications (2)

Publication Number Publication Date
JP2013545728A true JP2013545728A (ja) 2013-12-26
JP2013545728A5 JP2013545728A5 (enExample) 2014-11-20

Family

ID=45975842

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2013535012A Pending JP2013545728A (ja) 2010-10-19 2011-10-18 抗菌性ポリエーテルおよびポリオール化合物

Country Status (12)

Country Link
US (1) US9248117B2 (enExample)
EP (1) EP2629607A4 (enExample)
JP (1) JP2013545728A (enExample)
KR (1) KR20130123383A (enExample)
CN (1) CN103260402A (enExample)
AU (1) AU2011317223A1 (enExample)
BR (1) BR112013009279A2 (enExample)
CA (1) CA2814378A1 (enExample)
IL (1) IL225838A0 (enExample)
MX (1) MX2013004311A (enExample)
SG (1) SG189857A1 (enExample)
WO (1) WO2012054521A2 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7635390B1 (en) 2000-01-14 2009-12-22 Marctec, Llc Joint replacement component having a modular articulating surface
GB201121768D0 (en) * 2011-12-16 2012-02-01 Univ Swansea Compounds
JP2015523331A (ja) * 2012-05-17 2015-08-13 ユニヴァーシティー オブ マニトバ 殺生物化合物及びその使用方法
WO2017197518A1 (en) * 2016-05-18 2017-11-23 Exigence Technologies Inc. Compounds with one or more functional groups and use thereof in liquid disinfectants
EP3870182A4 (en) * 2018-10-26 2021-12-22 University of South Alabama FUNCTIONALIZED MATERIALS AND COMPOUNDS
WO2022091091A1 (en) * 2020-10-29 2022-05-05 Technion Research & Development Foundation Ltd. Polymeric disinfectants and uses thereof

Citations (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6269883A (ja) * 1985-09-20 1987-03-31 日東紡績株式会社 繊維用抗菌剤
JPS63270800A (ja) * 1986-05-28 1988-11-08 Lion Corp 漂白剤組成物
EP0437900A1 (de) * 1989-12-28 1991-07-24 Roland Dr. Dipl.-Chem. Ohme Desinfektionsmittellösung zur verbesserten Keimabtötung
JP2003248200A (ja) * 2002-01-14 2003-09-05 Johnson & Johnson Vision Care Inc 複素環式化合物を含む眼用器具およびその製造方法
WO2006099567A2 (en) * 2005-03-11 2006-09-21 Auburn University Biocidal n-halamine epoxides
WO2007102705A1 (en) * 2006-03-07 2007-09-13 Hee Jung Kim Anion receptor and electrolyte using the same
WO2008083347A1 (en) * 2006-12-29 2008-07-10 Novabay Pharmaceuticals, Inc. N-halogenated amino compounds and derivatives
WO2009126912A1 (en) * 2008-04-10 2009-10-15 Novabay Pharmaceuticals, Inc. Compositions comprising n-halogenated or n, n-dihalogenated amine for treatment and prophylaxis of bronchopulmonary infections
WO2010017405A1 (en) * 2008-08-06 2010-02-11 Adam Heller Methods and compositions for the treatment of pain
US20100076089A1 (en) * 2008-08-12 2010-03-25 Novabay Pharmaceuticals, Inc. Antimicrobial gel formulations
JP2010516815A (ja) * 2007-01-31 2010-05-20 ヘラー， アダム 疼痛の治療のための方法および組成物
US20100137349A1 (en) * 2008-11-07 2010-06-03 Novabay Pharmaceuticals, Inc. Antimicrobial oxazolidinone, hydantoin and imidazolidinone compositions
US20100158818A1 (en) * 2008-11-07 2010-06-24 Novabay Pharmaceuticals, Inc. Antimicrobial n-chlorinated compositions
WO2010124237A1 (en) * 2009-04-24 2010-10-28 Novabay Pharmaceuticals Inc. Methods of treating infections of the nail

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4234188C2 (de) * 1992-10-10 1996-01-11 Beiersdorf Ag Antimycotische kosmetische und dermatologische Verwendungen
DK1656095T3 (en) 2003-08-18 2014-03-10 Novabay Pharmaceuticals Inc N, N-DIHALOGENG-GENERATED AMINO ACIDS AND DERIVATIVES
US20120101018A1 (en) * 2010-10-22 2012-04-26 Gregory Scot Miracle Bis-azo colorants for use as bluing agents

Patent Citations (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6269883A (ja) * 1985-09-20 1987-03-31 日東紡績株式会社 繊維用抗菌剤
JPS63270800A (ja) * 1986-05-28 1988-11-08 Lion Corp 漂白剤組成物
EP0437900A1 (de) * 1989-12-28 1991-07-24 Roland Dr. Dipl.-Chem. Ohme Desinfektionsmittellösung zur verbesserten Keimabtötung
JP2003248200A (ja) * 2002-01-14 2003-09-05 Johnson & Johnson Vision Care Inc 複素環式化合物を含む眼用器具およびその製造方法
WO2006099567A2 (en) * 2005-03-11 2006-09-21 Auburn University Biocidal n-halamine epoxides
WO2007102705A1 (en) * 2006-03-07 2007-09-13 Hee Jung Kim Anion receptor and electrolyte using the same
WO2008083347A1 (en) * 2006-12-29 2008-07-10 Novabay Pharmaceuticals, Inc. N-halogenated amino compounds and derivatives
JP2010516815A (ja) * 2007-01-31 2010-05-20 ヘラー， アダム 疼痛の治療のための方法および組成物
WO2009126912A1 (en) * 2008-04-10 2009-10-15 Novabay Pharmaceuticals, Inc. Compositions comprising n-halogenated or n, n-dihalogenated amine for treatment and prophylaxis of bronchopulmonary infections
WO2010017405A1 (en) * 2008-08-06 2010-02-11 Adam Heller Methods and compositions for the treatment of pain
US20100076089A1 (en) * 2008-08-12 2010-03-25 Novabay Pharmaceuticals, Inc. Antimicrobial gel formulations
US20100137349A1 (en) * 2008-11-07 2010-06-03 Novabay Pharmaceuticals, Inc. Antimicrobial oxazolidinone, hydantoin and imidazolidinone compositions
US20100158818A1 (en) * 2008-11-07 2010-06-24 Novabay Pharmaceuticals, Inc. Antimicrobial n-chlorinated compositions
WO2010124237A1 (en) * 2009-04-24 2010-10-28 Novabay Pharmaceuticals Inc. Methods of treating infections of the nail

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
JPN6015030624; Ｌｏｗ，　Ｅ．；　ｅｔ　ａｌ: 'Ｎ，Ｎ-Ｄｉｃｈｌｉｒｏａｍｉｎｏｓｕｌｆｏｎｉｃ　ａｃｉｄｓ　ａｓ　ｎｏｖｅｌ　ｔｏｐｉｃａｌ　ａｎｔｉｍｉｃｒｏｂｉａｌ　ａｇｅｎｔｓ' Ｂｉｏｏｒｇａｎｉｃ　＆　Ｍｅｄｉｃｉｎａｌ　Ｃｈｅｍｉｓｔｒｙ　Ｌｅｔｔｅｒｓ Ｖｏｌ．１９, 2009, ｐ．１９６-１９８ *
JPN6015030626; Ａｎｔｅｌｏ，　Ｊｕａｎ　Ｍａｎｕｅｌ；　Ａｒｃｅ，　Ｆｌｏｒｅｎｃｉｏ；　Ｐａｒａｊｏ，　Ｍｅｒｃｅｄｅｓ；　Ｒｏｄｒｉｇｕｅｚ　Ｂａｒｒｏ，　Ｐｉｌａｒ: 'Ｉｎｆｌｕｅｎｃｅ　ｏｆ　ｓｕｂｓｔｉｔｕｅｎｔｓ　ｏｎ　ｔｈｅ　ｒａｔｅ　ｏｆ　ｆｏｒｍａｔｉｏｎ　ｏｆ　ｄｉｃｈｌｏｒａｍｉｎｅｓ' Ｇａｚｚｅｔｔａ　Ｃｈｉｍｉｃａ　Ｉｔａｌｉａｎａ Ｖｏｌ．１２３（１０）, 1993, ｐ．５４９-５５２ *
JPN6015030630; Ａｎｔｅｌｏ，　Ｊ．　Ｍ．；　Ａｒｃｅ，　Ｆ．；　Ｃａｓａｌ，　Ｄ．；　Ｒｏｄｒｉｇｕｅｚ，　Ｐ．；　Ｖａｒｅｌａ，　Ａ: 'Ｉｎｆｌｕｅｎｃｅ　ｏｆ　ｐＨ　ｏｎ　ｔｈｅ　ｄｅｃｏｍｐｏｓｉｔｉｏｎ　ｏｆ　Ｎ-ｃｈｌｏｒｏｄｉｅｔｈａｎｏｌａｍｉｎｅ' Ｔｅｔｒａｈｅｄｒｏｎ Ｖｏｌ．４５（１２）, 1989, ｐ．３９５５-３９６６ *

Also Published As

Publication number Publication date
SG189857A1 (en) 2013-06-28
US20120129793A1 (en) 2012-05-24
WO2012054521A2 (en) 2012-04-26
EP2629607A2 (en) 2013-08-28
US9248117B2 (en) 2016-02-02
EP2629607A4 (en) 2014-08-20
KR20130123383A (ko) 2013-11-12
CN103260402A (zh) 2013-08-21
WO2012054521A8 (en) 2012-08-30
BR112013009279A2 (pt) 2016-07-26
AU2011317223A1 (en) 2013-05-23
WO2012054521A3 (en) 2012-07-19
MX2013004311A (es) 2013-12-02
CA2814378A1 (en) 2012-04-26
IL225838A0 (en) 2013-06-27

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