CA2814378A1 - Antimicrobial polyether and polyol compounds - Google Patents

Antimicrobial polyether and polyol compounds Download PDF

Info

Publication number
CA2814378A1
CA2814378A1 CA2814378A CA2814378A CA2814378A1 CA 2814378 A1 CA2814378 A1 CA 2814378A1 CA 2814378 A CA2814378 A CA 2814378A CA 2814378 A CA2814378 A CA 2814378A CA 2814378 A1 CA2814378 A1 CA 2814378A1
Authority
CA
Canada
Prior art keywords
ethoxy
chloro
mmol
dichloroamino
solution
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA2814378A
Other languages
English (en)
French (fr)
Inventor
Rakesh K. Jain
Timothy Shiau
Charles Francavilla
Eddy Low
Eric Douglas Turtle
Donogh John Roger O'mahony
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novabay Pharmaceuticals Inc
Original Assignee
Novabay Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novabay Pharmaceuticals Inc filed Critical Novabay Pharmaceuticals Inc
Publication of CA2814378A1 publication Critical patent/CA2814378A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4166—1,3-Diazoles having oxo groups directly attached to the heterocyclic ring, e.g. phenytoin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
    • C07C309/01—Sulfonic acids
    • C07C309/02—Sulfonic acids having sulfo groups bound to acyclic carbon atoms
    • C07C309/03—Sulfonic acids having sulfo groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
    • C07C309/13—Sulfonic acids having sulfo groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton containing nitrogen atoms, not being part of nitro or nitroso groups, bound to the carbon skeleton
    • C07C309/14—Sulfonic acids having sulfo groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton containing nitrogen atoms, not being part of nitro or nitroso groups, bound to the carbon skeleton containing amino groups bound to the carbon skeleton
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N33/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic nitrogen compounds
    • A01N33/02—Amines; Quaternary ammonium compounds
    • A01N33/08—Amines; Quaternary ammonium compounds containing oxygen or sulfur
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/02—Local antiseptics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C239/00—Compounds containing nitrogen-to-halogen bonds; Hydroxylamino compounds or ethers or esters thereof
    • C07C239/02—Compounds containing nitrogen-to-halogen bonds
    • C07C239/04—N-halogenated amines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • C07C317/26—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
    • C07C317/28—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton with sulfone or sulfoxide groups bound to acyclic carbon atoms of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Biochemistry (AREA)
  • Dermatology (AREA)
  • Wood Science & Technology (AREA)
  • Virology (AREA)
  • Agronomy & Crop Science (AREA)
  • Pest Control & Pesticides (AREA)
  • Plant Pathology (AREA)
  • Dentistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Saccharide Compounds (AREA)
CA2814378A 2010-10-19 2011-10-18 Antimicrobial polyether and polyol compounds Abandoned CA2814378A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US39469710P 2010-10-19 2010-10-19
US61/394,697 2010-10-19
US41833410P 2010-11-30 2010-11-30
US61/418,334 2010-11-30
PCT/US2011/056764 WO2012054521A2 (en) 2010-10-19 2011-10-18 Antimicrobial polyether and polyol compounds

Publications (1)

Publication Number Publication Date
CA2814378A1 true CA2814378A1 (en) 2012-04-26

Family

ID=45975842

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2814378A Abandoned CA2814378A1 (en) 2010-10-19 2011-10-18 Antimicrobial polyether and polyol compounds

Country Status (12)

Country Link
US (1) US9248117B2 (enExample)
EP (1) EP2629607A4 (enExample)
JP (1) JP2013545728A (enExample)
KR (1) KR20130123383A (enExample)
CN (1) CN103260402A (enExample)
AU (1) AU2011317223A1 (enExample)
BR (1) BR112013009279A2 (enExample)
CA (1) CA2814378A1 (enExample)
IL (1) IL225838A0 (enExample)
MX (1) MX2013004311A (enExample)
SG (1) SG189857A1 (enExample)
WO (1) WO2012054521A2 (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013173905A1 (en) * 2012-05-17 2013-11-28 University Of Manitoba Biocidal compounds and methods for using same
WO2017197518A1 (en) * 2016-05-18 2017-11-23 Exigence Technologies Inc. Compounds with one or more functional groups and use thereof in liquid disinfectants

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7635390B1 (en) 2000-01-14 2009-12-22 Marctec, Llc Joint replacement component having a modular articulating surface
GB201121768D0 (en) * 2011-12-16 2012-02-01 Univ Swansea Compounds
US11192883B2 (en) 2018-10-26 2021-12-07 University Of South Alabama Functionalized materials and compounds
WO2022091091A1 (en) * 2020-10-29 2022-05-05 Technion Research & Development Foundation Ltd. Polymeric disinfectants and uses thereof

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6269883A (ja) * 1985-09-20 1987-03-31 日東紡績株式会社 繊維用抗菌剤
JPH0813996B2 (ja) * 1986-05-28 1996-02-14 ライオン株式会社 漂白剤組成物
DD300072A5 (de) * 1989-12-28 1992-05-21 Akad Wissenschaften Ddr Desinfektionsmittellösung zur verbesserten Keimabtötung
DE4234188C2 (de) * 1992-10-10 1996-01-11 Beiersdorf Ag Antimycotische kosmetische und dermatologische Verwendungen
US7173073B2 (en) * 2002-01-14 2007-02-06 Johnson & Johnson Vision Care, Inc. Ophthalmic devices containing heterocyclic compounds and methods for their production
PT1656095E (pt) 2003-08-18 2014-03-11 Novabay Pharmaceuticals Inc Aminoácidos n,n-dihalogenados e seus derivados
WO2006099567A2 (en) * 2005-03-11 2006-09-21 Auburn University Biocidal n-halamine epoxides
WO2007102705A1 (en) * 2006-03-07 2007-09-13 Hee Jung Kim Anion receptor and electrolyte using the same
TW200843787A (en) * 2006-12-29 2008-11-16 Novabay Pharmaceuticals Inc N-halogenated amino compounds and derivatives; compositions and methods of using them
EP2111252A4 (en) * 2007-01-31 2010-12-01 Adam Heller MANAGEMENT OF PAIN BY ELECTROCHEMICAL PATHWAY
JP2011516578A (ja) * 2008-04-10 2011-05-26 ノバベイ・ファーマシューティカルズ・インコーポレイテッド 気管支肺感染症の治療および予防のための組成物および方法
WO2010017405A1 (en) * 2008-08-06 2010-02-11 Adam Heller Methods and compositions for the treatment of pain
AU2009281998A1 (en) * 2008-08-12 2010-02-18 Novabay Pharmaceuticals, Inc. Antimicrobial gel formulations
WO2010054009A1 (en) * 2008-11-07 2010-05-14 Novabay Pharmaceuticals, Inc. Antimicrobial oxazolidinone, hydantoin and imidazolidinone compositions
JP5599808B2 (ja) * 2008-11-07 2014-10-01 ノバベイ・ファーマシューティカルズ・インコーポレイテッド 抗菌性ｎ−塩素化組成物
US20100272783A1 (en) * 2009-04-24 2010-10-28 Novabay Pharmaceuticals, Inc. Methods of Treating Infections of the Nail
US20120101018A1 (en) * 2010-10-22 2012-04-26 Gregory Scot Miracle Bis-azo colorants for use as bluing agents

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013173905A1 (en) * 2012-05-17 2013-11-28 University Of Manitoba Biocidal compounds and methods for using same
WO2017197518A1 (en) * 2016-05-18 2017-11-23 Exigence Technologies Inc. Compounds with one or more functional groups and use thereof in liquid disinfectants

Also Published As

Publication number Publication date
BR112013009279A2 (pt) 2016-07-26
AU2011317223A1 (en) 2013-05-23
US9248117B2 (en) 2016-02-02
MX2013004311A (es) 2013-12-02
EP2629607A2 (en) 2013-08-28
KR20130123383A (ko) 2013-11-12
US20120129793A1 (en) 2012-05-24
SG189857A1 (en) 2013-06-28
CN103260402A (zh) 2013-08-21
WO2012054521A8 (en) 2012-08-30
JP2013545728A (ja) 2013-12-26
WO2012054521A2 (en) 2012-04-26
WO2012054521A3 (en) 2012-07-19
IL225838A0 (en) 2013-06-27
EP2629607A4 (en) 2014-08-20

Similar Documents

Publication Publication Date Title
CA2985542C (en) Triazole agonists of the apj receptor
AU2016281710B2 (en) 3-tetrazolyl-benzene-1,2-disulfonamide derivatives as metallo-Beta-lactamase inhibitors
KR101454936B1 (ko) Ｂｃｌ 단백질과 결합 파트너의 상호작용을 억제하기 위한 화합물 및 방법
US20190275008A1 (en) Triazole furan compounds as agonists of the apj receptor
US20190284173A1 (en) Triazole phenyl compounds as agonists of the apj receptor
JP5599808B2 (ja) 抗菌性ｎ−塩素化組成物
US9248117B2 (en) Substituted N,N-dihaloamines as antimicrobials
US20220274961A1 (en) Substituted fused bi- or tri- heterocyclic compounds as ehmt2 inhibitors
EA021260B1 (ru) Ингибиторы вируса гепатита с
JP5753785B2 (ja) 抗菌オキサゾリジノン、ヒダントインおよびイミダゾリジノン組成物
US12384753B2 (en) 17-beta-hydroxysteroid dehydrogenase type 13 inhibitors and methods of use thereof
US11767322B2 (en) Triazolopyridinyl compounds as kinase inhibitors
US20250179055A1 (en) Substituted 2-(pyrrolidine-3-yl)acetic acid derivative, preparation method and use thereof
WO2019241751A1 (en) Ssao inhibitors and uses thereof
AU2025208562A1 (en) Heterocyclic carboxylate compounds as glycolate oxidase inhibitors
US20240374573A1 (en) Imidazole containing compounds, derivatives therefore, and uses thereof
EP2632255A1 (en) Diazeniumdiolate heterocyclic derivatives
CA3253274A1 (en) COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF CONDITIONS ASSOCIATED WITH THE ACTIVITY OF THE LPA RECIPIENT
JP2023501577A (ja) ５－ヒドロキシトリプタミン受容体７の調節因子としての新規官能化ラクタムおよびその使用方法
CN114423775B (zh) 一类芳基葡糖苷衍生物及其制备方法和应用
CN115003661B (zh) 芳基葡糖苷衍生物及其在药物中的用途
US20140094495A1 (en) Antimicrobial Haloalkyl Heterocycle Compounds
US20120041194A1 (en) Nitrogen and sulfur-containing hetrocycle derivatives
HK40119559A (en) Compounds and compositions for treating conditions associated with lpa receptor activity
CA3024482C (en) Macrocyclic indole derivatives

Legal Events

Date Code Title Description
FZDE Discontinued

Effective date: 20171018