JP2013544812A5 - - Google Patents

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Publication number
JP2013544812A5
JP2013544812A5 JP2013537808A JP2013537808A JP2013544812A5 JP 2013544812 A5 JP2013544812 A5 JP 2013544812A5 JP 2013537808 A JP2013537808 A JP 2013537808A JP 2013537808 A JP2013537808 A JP 2013537808A JP 2013544812 A5 JP2013544812 A5 JP 2013544812A5
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JP
Japan
Prior art keywords
alkyl
cycloalkyl
optionally substituted
hydrogen
nhc
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2013537808A
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English (en)
Japanese (ja)
Other versions
JP5891235B2 (ja
JP2013544812A (ja
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Publication date
Application filed filed Critical
Priority claimed from PCT/US2011/059061 external-priority patent/WO2012061552A1/en
Publication of JP2013544812A publication Critical patent/JP2013544812A/ja
Publication of JP2013544812A5 publication Critical patent/JP2013544812A5/ja
Application granted granted Critical
Publication of JP5891235B2 publication Critical patent/JP5891235B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2013537808A 2010-11-04 2011-11-03 C型肝炎ウイルスの新規阻害剤 Expired - Fee Related JP5891235B2 (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US41026710P 2010-11-04 2010-11-04
US61/410,267 2010-11-04
US201161444046P 2011-02-17 2011-02-17
US61/444,046 2011-02-17
US201161492267P 2011-06-01 2011-06-01
US61/492,267 2011-06-01
PCT/US2011/059061 WO2012061552A1 (en) 2010-11-04 2011-11-03 Novel inhibitors of hepatitis c virus

Publications (3)

Publication Number Publication Date
JP2013544812A JP2013544812A (ja) 2013-12-19
JP2013544812A5 true JP2013544812A5 (US20080131398A1-20080605-C00009.png) 2014-11-06
JP5891235B2 JP5891235B2 (ja) 2016-03-22

Family

ID=44993923

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2013537808A Expired - Fee Related JP5891235B2 (ja) 2010-11-04 2011-11-03 C型肝炎ウイルスの新規阻害剤

Country Status (9)

Country Link
US (2) US8921372B2 (US20080131398A1-20080605-C00009.png)
EP (1) EP2635571B1 (US20080131398A1-20080605-C00009.png)
JP (1) JP5891235B2 (US20080131398A1-20080605-C00009.png)
CN (1) CN103189371B (US20080131398A1-20080605-C00009.png)
AR (1) AR083757A1 (US20080131398A1-20080605-C00009.png)
CA (1) CA2814534A1 (US20080131398A1-20080605-C00009.png)
ES (1) ES2548286T3 (US20080131398A1-20080605-C00009.png)
TW (1) TW201249827A (US20080131398A1-20080605-C00009.png)
WO (1) WO2012061552A1 (US20080131398A1-20080605-C00009.png)

Families Citing this family (23)

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WO2008156620A1 (en) * 2007-06-12 2008-12-24 Technolines, Llc High speed and high power laser scribing methods and systems
DK2455376T3 (en) 2009-06-11 2015-03-02 Abbvie Bahamas Ltd Heterocyclic compounds as inhibitors of hepatitis C virus (HCV)
US8937150B2 (en) 2009-06-11 2015-01-20 Abbvie Inc. Anti-viral compounds
NZ605440A (en) 2010-06-10 2014-05-30 Abbvie Bahamas Ltd Solid compositions comprising an hcv inhibitor
ES2548286T3 (es) * 2010-11-04 2015-10-15 Theravance Biopharma R&D Ip, Llc Nuevos inhibidores del virus de la hepatitis C
US8552047B2 (en) 2011-02-07 2013-10-08 Bristol-Myers Squibb Company Hepatitis C virus inhibitors
US9546160B2 (en) 2011-05-12 2017-01-17 Bristol-Myers Squibb Company Hepatitis C virus inhibitors
US10201584B1 (en) 2011-05-17 2019-02-12 Abbvie Inc. Compositions and methods for treating HCV
EP2723732B1 (en) 2011-06-22 2017-01-18 Purdue Pharma LP Trpv1 antagonists including dihydroxy substituent and uses thereof
BR112014010401A8 (pt) 2011-11-03 2017-12-19 Theravance Inc Inibidores do vírus da hepatite c rod-like que contêm o fragmento {2-[4-(bifenil-4-il)-1h-imidazo-2-il] pirrolidina-1-carbonilmetil}amina
US9034832B2 (en) 2011-12-29 2015-05-19 Abbvie Inc. Solid compositions
US9326973B2 (en) 2012-01-13 2016-05-03 Bristol-Myers Squibb Company Hepatitis C virus inhibitors
US9206159B2 (en) 2012-04-25 2015-12-08 Theravance Biopharma R&D Ip, Llc Piperazine-piperidine compounds as hepatitis C virus inhibitors
WO2013163270A1 (en) * 2012-04-25 2013-10-31 Theravance, Inc. Hepatitis c virus inhibitors
US8883135B2 (en) 2012-05-03 2014-11-11 Theravance Biopharma R&D Ip, Llc Crystalline form of a pyridyl-piperazinyl hepatitis C virus inhibitor
US11484534B2 (en) 2013-03-14 2022-11-01 Abbvie Inc. Methods for treating HCV
US9717712B2 (en) 2013-07-02 2017-08-01 Bristol-Myers Squibb Company Combinations comprising tricyclohexadecahexaene derivatives for use in the treatment of hepatitis C virus
US20150023913A1 (en) 2013-07-02 2015-01-22 Bristol-Myers Squibb Company Hepatitis C Virus Inhibitors
US9775831B2 (en) 2013-07-17 2017-10-03 Bristol-Myers Squibb Company Combinations comprising biphenyl derivatives for use in the treatment of HCV
WO2015103490A1 (en) 2014-01-03 2015-07-09 Abbvie, Inc. Solid antiviral dosage forms
US10617675B2 (en) 2015-08-06 2020-04-14 Bristol-Myers Squibb Company Hepatitis C virus inhibitors
CN105175401A (zh) * 2015-10-16 2015-12-23 北京康立生医药技术开发有限公司 一种依匹哌唑的制备方法
CN112409336B (zh) * 2017-11-27 2021-09-14 常州寅盛药业有限公司 适于工业化生产的达卡他韦起始原料的合成方法

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0421908D0 (en) * 2004-10-01 2004-11-03 Angeletti P Ist Richerche Bio New uses
DE602006016313D1 (de) * 2005-09-16 2010-09-30 Arrow Therapeutics Ltd Biphenylderivate und ihre verwendung bei der behandlung von hepatitis c
US8303944B2 (en) 2006-08-11 2012-11-06 Bristol-Myers Squibb Company Hepatitis C virus inhibitors
US7659270B2 (en) 2006-08-11 2010-02-09 Bristol-Myers Squibb Company Hepatitis C virus inhibitors
US8329159B2 (en) 2006-08-11 2012-12-11 Bristol-Myers Squibb Company Hepatitis C virus inhibitors
US7745636B2 (en) 2006-08-11 2010-06-29 Bristol-Myers Squibb Company Hepatitis C virus inhibitors
CN101558059B (zh) * 2006-08-11 2014-12-03 百时美施贵宝公司 丙型肝炎病毒抑制剂
US7910722B2 (en) * 2007-07-05 2011-03-22 Florida State University Research Foundation RNAi therapeutic for treatment of hepatitis C infection
PT2250163E (pt) 2008-02-12 2012-06-01 Bristol Myers Squibb Co Inibidores do vírus da hepatite c
KR20110098779A (ko) 2008-12-03 2011-09-01 프레시디오 파마슈티칼스, 인코포레이티드 Hcv ns5a의 억제제
UY32462A (es) 2009-02-23 2010-09-30 Arrow Therapeutics Ltd Derivados de bifenilo novedosos para el tratamiento de infección por virus de hepatitis c 644
CA2753313A1 (en) 2009-02-23 2010-08-26 Presidio Pharmaceuticals, Inc. Inhibitors of hcv ns5a
WO2011031934A1 (en) 2009-09-11 2011-03-17 Enanta Pharmaceuticals, Inc. Hepatitis c virus inhibitors
US8822700B2 (en) 2009-09-11 2014-09-02 Enanta Pharmaceuticals, Inc. Hepatitis C virus inhibitors
EP2512480A4 (en) 2009-12-14 2013-05-15 Enanta Pharm Inc HEPATITIS C-VIRUS HEMMER
US8377980B2 (en) 2009-12-16 2013-02-19 Bristol-Myers Squibb Company Hepatitis C virus inhibitors
EP2575819A4 (en) 2010-06-04 2013-11-27 Enanta Pharm Inc INHIBITORS OF HEPATITIS C VIRUS
ES2548286T3 (es) * 2010-11-04 2015-10-15 Theravance Biopharma R&D Ip, Llc Nuevos inhibidores del virus de la hepatitis C
BR112014010401A8 (pt) 2011-11-03 2017-12-19 Theravance Inc Inibidores do vírus da hepatite c rod-like que contêm o fragmento {2-[4-(bifenil-4-il)-1h-imidazo-2-il] pirrolidina-1-carbonilmetil}amina

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