JP2013544254A5 - - Google Patents
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- JP2013544254A5 JP2013544254A5 JP2013539982A JP2013539982A JP2013544254A5 JP 2013544254 A5 JP2013544254 A5 JP 2013544254A5 JP 2013539982 A JP2013539982 A JP 2013539982A JP 2013539982 A JP2013539982 A JP 2013539982A JP 2013544254 A5 JP2013544254 A5 JP 2013544254A5
- Authority
- JP
- Japan
- Prior art keywords
- combination
- receptor antagonist
- chemotherapeutic agent
- prolactin receptor
- patient
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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| WO2013167750A2 (en) * | 2012-05-11 | 2013-11-14 | Prorec Bio Ab | Method for diagnosis and treatment of prolactin associated disorders |
| WO2014105810A1 (en) | 2012-12-24 | 2014-07-03 | Abbvie Inc. | Prolactin receptor binding proteins and uses thereof |
| EP3125920B1 (en) | 2014-04-04 | 2020-12-23 | Del Mar Pharmaceuticals | Dianhydrogalactitol, diacetyldianhydrogalactitol or dibromodulcitol to treat non-small-cell carcinoma of the lung and ovarian cancer |
| TW201836647A (zh) | 2017-04-06 | 2018-10-16 | 美商艾伯維有限公司 | 抗－ｐｒｌｒ抗體藥物軛合物（ａｄｃ）及其用途 |
| EP3707166A4 (en) * | 2017-11-06 | 2021-11-24 | Daniel J. Monticello | CHEMICAL ANTIGENIC RECEPTOR SYSTEMS WITH NEGATIVE DOMINANT LIGAND |
| WO2019169330A1 (en) * | 2018-03-02 | 2019-09-06 | Oncolix, Inc. | Method for treating cancers expressing prolactin receptor |
| UY39610A (es) | 2021-01-20 | 2022-08-31 | Abbvie Inc | Conjugados anticuerpo-fármaco anti-egfr |
| CN113956356B (zh) * | 2021-10-27 | 2023-05-02 | 福州迈新生物技术开发有限公司 | 抗prl蛋白单克隆抗体、细胞系及其应用 |
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| CA1055932A (en) | 1975-10-22 | 1979-06-05 | Hematech Inc. | Blood substitute based on hemoglobin |
| DE2616086C2 (de) | 1976-04-13 | 1986-04-03 | Dr. Eduard Fresenius, Chemisch-pharmazeutische Industrie KG, 6380 Bad Homburg | Substanz zur Verwendung in einem kolloidalen Blutvolumenersatzmittel aus Hydroxyethylstärke und Hämoglobin |
| CA2328520C (en) | 1998-05-12 | 2013-06-25 | Wen Y. Chen | Use of anti-prolactin agents to treat proliferative conditions |
| DE60030323T2 (de) | 1999-12-24 | 2007-10-11 | Genentech, Inc., South San Francisco | Verfahren und verbindungen zur verlängerung der halbwertzeiten bei der ausscheidung von biowirksamen verbindungen |
| US7094750B2 (en) | 2000-05-09 | 2006-08-22 | Greenville Hospital System | Therapeutic pore-forming peptides |
| AU2003230750A1 (en) * | 2002-03-29 | 2003-10-13 | Threshold Pharmaceuticals, Inc. | Compositions and methods for treating cancer |
| RU2329274C2 (ru) | 2002-09-11 | 2008-07-20 | Фрезениус Каби Дойчланд Гмбх | Способ получения производных гидроксиалкилкрахмала |
| KR101162908B1 (ko) * | 2002-12-26 | 2012-07-06 | 마운틴 뷰 파마슈티컬즈, 인크. | 수용체-결합 활성이 보존된, 사이토카인, 케모카인,성장인자, 폴리펩티드 호르몬 및 이들의 길항제의 중합체접합체 |
| US8754031B2 (en) * | 2004-03-08 | 2014-06-17 | Oncolix, Inc. | Use of prolactin receptor antagonists in combination with an agent that inactivates the HER2/neu signaling pathway |
| US20050238628A1 (en) * | 2004-04-08 | 2005-10-27 | Blau Carl A | Methods for treating cancer |
| US7422899B2 (en) * | 2005-10-05 | 2008-09-09 | Biogen Idec Ma Inc. | Antibodies to the human prolactin receptor |
| CN100479863C (zh) * | 2006-09-06 | 2009-04-22 | 中国医学科学院北京协和医院 | Cofilin 1与癌症的紫杉烷类化疗药物耐药性的相关性 |
| JP2010513405A (ja) * | 2006-12-21 | 2010-04-30 | ノボ・ノルデイスク・エー／エス | 二量体プロラクチンレセプターリガンド |
| US8420665B2 (en) * | 2008-01-11 | 2013-04-16 | Northwestern University | Anti-cancer compounds |
| CN106177954A (zh) * | 2009-02-26 | 2016-12-07 | 翁科里克斯公司 | 使癌干细胞可视化并消除癌干细胞的组合物和方法 |
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