JP6306886B2 - 卵巣がんを治療するためのプロラクチン受容体拮抗薬および化学療法剤の使用 - Google Patents
卵巣がんを治療するためのプロラクチン受容体拮抗薬および化学療法剤の使用 Download PDFInfo
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- JP6306886B2 JP6306886B2 JP2013539982A JP2013539982A JP6306886B2 JP 6306886 B2 JP6306886 B2 JP 6306886B2 JP 2013539982 A JP2013539982 A JP 2013539982A JP 2013539982 A JP2013539982 A JP 2013539982A JP 6306886 B2 JP6306886 B2 JP 6306886B2
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- prolactin
- prolactin receptor
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- ovarian cancer
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- A61K38/22—Hormones
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- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/2257—Prolactin
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- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
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- A—HUMAN NECESSITIES
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Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
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| US12/948,329 | 2010-11-17 | ||
| PCT/US2011/061040 WO2012068282A1 (en) | 2010-11-17 | 2011-11-16 | Use of prolactin receptor antagonist and chemotherapeutic drug for treating ovarian cancer |
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| JP2015227552A Division JP2016029110A (ja) | 2010-11-17 | 2015-11-20 | 卵巣がんを治療するためのプロラクチン受容体拮抗薬および化学療法剤の使用 |
| JP2018008262A Division JP2018062527A (ja) | 2010-11-17 | 2018-01-22 | 卵巣がんを治療するためのプロラクチン受容体拮抗薬および化学療法剤の使用 |
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| JP2013544254A JP2013544254A (ja) | 2013-12-12 |
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| JP2013539982A Expired - Fee Related JP6306886B2 (ja) | 2010-11-17 | 2011-11-16 | 卵巣がんを治療するためのプロラクチン受容体拮抗薬および化学療法剤の使用 |
| JP2015227552A Pending JP2016029110A (ja) | 2010-11-17 | 2015-11-20 | 卵巣がんを治療するためのプロラクチン受容体拮抗薬および化学療法剤の使用 |
| JP2018008262A Withdrawn JP2018062527A (ja) | 2010-11-17 | 2018-01-22 | 卵巣がんを治療するためのプロラクチン受容体拮抗薬および化学療法剤の使用 |
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| JP2018008262A Withdrawn JP2018062527A (ja) | 2010-11-17 | 2018-01-22 | 卵巣がんを治療するためのプロラクチン受容体拮抗薬および化学療法剤の使用 |
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| Country | Link |
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| US (2) | US8648046B2 (enExample) |
| EP (1) | EP2640412B1 (enExample) |
| JP (3) | JP6306886B2 (enExample) |
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| CN (2) | CN106177915A (enExample) |
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| IL (1) | IL226271A (enExample) |
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| WO2013167750A2 (en) * | 2012-05-11 | 2013-11-14 | Prorec Bio Ab | Method for diagnosis and treatment of prolactin associated disorders |
| WO2014105810A1 (en) | 2012-12-24 | 2014-07-03 | Abbvie Inc. | Prolactin receptor binding proteins and uses thereof |
| EP3125920B1 (en) | 2014-04-04 | 2020-12-23 | Del Mar Pharmaceuticals | Dianhydrogalactitol, diacetyldianhydrogalactitol or dibromodulcitol to treat non-small-cell carcinoma of the lung and ovarian cancer |
| TW201836647A (zh) | 2017-04-06 | 2018-10-16 | 美商艾伯維有限公司 | 抗－ｐｒｌｒ抗體藥物軛合物（ａｄｃ）及其用途 |
| EP3707166A4 (en) * | 2017-11-06 | 2021-11-24 | Daniel J. Monticello | CHEMICAL ANTIGENIC RECEPTOR SYSTEMS WITH NEGATIVE DOMINANT LIGAND |
| WO2019169330A1 (en) * | 2018-03-02 | 2019-09-06 | Oncolix, Inc. | Method for treating cancers expressing prolactin receptor |
| UY39610A (es) | 2021-01-20 | 2022-08-31 | Abbvie Inc | Conjugados anticuerpo-fármaco anti-egfr |
| CN113956356B (zh) * | 2021-10-27 | 2023-05-02 | 福州迈新生物技术开发有限公司 | 抗prl蛋白单克隆抗体、细胞系及其应用 |
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| CA1055932A (en) | 1975-10-22 | 1979-06-05 | Hematech Inc. | Blood substitute based on hemoglobin |
| DE2616086C2 (de) | 1976-04-13 | 1986-04-03 | Dr. Eduard Fresenius, Chemisch-pharmazeutische Industrie KG, 6380 Bad Homburg | Substanz zur Verwendung in einem kolloidalen Blutvolumenersatzmittel aus Hydroxyethylstärke und Hämoglobin |
| CA2328520C (en) | 1998-05-12 | 2013-06-25 | Wen Y. Chen | Use of anti-prolactin agents to treat proliferative conditions |
| DE60030323T2 (de) | 1999-12-24 | 2007-10-11 | Genentech, Inc., South San Francisco | Verfahren und verbindungen zur verlängerung der halbwertzeiten bei der ausscheidung von biowirksamen verbindungen |
| US7094750B2 (en) | 2000-05-09 | 2006-08-22 | Greenville Hospital System | Therapeutic pore-forming peptides |
| AU2003230750A1 (en) * | 2002-03-29 | 2003-10-13 | Threshold Pharmaceuticals, Inc. | Compositions and methods for treating cancer |
| RU2329274C2 (ru) | 2002-09-11 | 2008-07-20 | Фрезениус Каби Дойчланд Гмбх | Способ получения производных гидроксиалкилкрахмала |
| KR101162908B1 (ko) * | 2002-12-26 | 2012-07-06 | 마운틴 뷰 파마슈티컬즈, 인크. | 수용체-결합 활성이 보존된, 사이토카인, 케모카인,성장인자, 폴리펩티드 호르몬 및 이들의 길항제의 중합체접합체 |
| US8754031B2 (en) * | 2004-03-08 | 2014-06-17 | Oncolix, Inc. | Use of prolactin receptor antagonists in combination with an agent that inactivates the HER2/neu signaling pathway |
| US20050238628A1 (en) * | 2004-04-08 | 2005-10-27 | Blau Carl A | Methods for treating cancer |
| US7422899B2 (en) * | 2005-10-05 | 2008-09-09 | Biogen Idec Ma Inc. | Antibodies to the human prolactin receptor |
| CN100479863C (zh) * | 2006-09-06 | 2009-04-22 | 中国医学科学院北京协和医院 | Cofilin 1与癌症的紫杉烷类化疗药物耐药性的相关性 |
| JP2010513405A (ja) * | 2006-12-21 | 2010-04-30 | ノボ・ノルデイスク・エー／エス | 二量体プロラクチンレセプターリガンド |
| US8420665B2 (en) * | 2008-01-11 | 2013-04-16 | Northwestern University | Anti-cancer compounds |
| CN106177954A (zh) * | 2009-02-26 | 2016-12-07 | 翁科里克斯公司 | 使癌干细胞可视化并消除癌干细胞的组合物和方法 |
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2011
- 2011-11-16 EP EP11796851.1A patent/EP2640412B1/en not_active Not-in-force
- 2011-11-16 CN CN201610675696.7A patent/CN106177915A/zh active Pending
- 2011-11-16 JP JP2013539982A patent/JP6306886B2/ja not_active Expired - Fee Related
- 2011-11-16 CA CA2817846A patent/CA2817846A1/en not_active Abandoned
- 2011-11-16 AU AU2011328935A patent/AU2011328935B2/en not_active Ceased
- 2011-11-16 US US13/988,014 patent/US20130231286A1/en not_active Abandoned
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- 2011-11-16 WO PCT/US2011/061040 patent/WO2012068282A1/en not_active Ceased
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Also Published As
| Publication number | Publication date |
|---|---|
| JP2013544254A (ja) | 2013-12-12 |
| CA2817846A1 (en) | 2012-05-24 |
| IL226271A0 (en) | 2013-07-31 |
| JP2016029110A (ja) | 2016-03-03 |
| CN106177915A (zh) | 2016-12-07 |
| KR20140009196A (ko) | 2014-01-22 |
| AU2011328935B2 (en) | 2016-08-11 |
| WO2012068282A1 (en) | 2012-05-24 |
| JP2018062527A (ja) | 2018-04-19 |
| EP2640412A1 (en) | 2013-09-25 |
| US20110065639A1 (en) | 2011-03-17 |
| US20130231286A1 (en) | 2013-09-05 |
| AU2011328935A1 (en) | 2013-05-30 |
| IL226271A (en) | 2017-05-29 |
| EP2640412B1 (en) | 2017-08-02 |
| US8648046B2 (en) | 2014-02-11 |
| CN103298481A (zh) | 2013-09-11 |
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