JP2013543760A5 - - Google Patents
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- Publication number
- JP2013543760A5 JP2013543760A5 JP2013538845A JP2013538845A JP2013543760A5 JP 2013543760 A5 JP2013543760 A5 JP 2013543760A5 JP 2013538845 A JP2013538845 A JP 2013538845A JP 2013538845 A JP2013538845 A JP 2013538845A JP 2013543760 A5 JP2013543760 A5 JP 2013543760A5
- Authority
- JP
- Japan
- Prior art keywords
- organ
- cells
- medical material
- subject
- lung
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000012567 medical material Substances 0.000 claims 12
- 210000000056 organ Anatomy 0.000 claims 11
- 210000002889 endothelial cell Anatomy 0.000 claims 10
- 210000004027 cell Anatomy 0.000 claims 9
- 210000004072 lung Anatomy 0.000 claims 8
- 239000008194 pharmaceutical composition Substances 0.000 claims 6
- 102100031573 Hematopoietic progenitor cell antigen CD34 Human genes 0.000 claims 5
- 101000777663 Homo sapiens Hematopoietic progenitor cell antigen CD34 Proteins 0.000 claims 5
- 101000851007 Homo sapiens Vascular endothelial growth factor receptor 2 Proteins 0.000 claims 5
- 102000008790 VE-cadherin Human genes 0.000 claims 5
- 102100033177 Vascular endothelial growth factor receptor 2 Human genes 0.000 claims 5
- 108010018828 cadherin 5 Proteins 0.000 claims 5
- 101001011906 Homo sapiens Matrix metalloproteinase-14 Proteins 0.000 claims 4
- 102100030216 Matrix metalloproteinase-14 Human genes 0.000 claims 4
- 108010073929 Vascular Endothelial Growth Factor A Proteins 0.000 claims 4
- 102100039037 Vascular endothelial growth factor A Human genes 0.000 claims 4
- 210000004185 liver Anatomy 0.000 claims 4
- 238000000034 method Methods 0.000 claims 4
- 230000008929 regeneration Effects 0.000 claims 4
- 238000011069 regeneration method Methods 0.000 claims 4
- 102000001690 Factor VIII Human genes 0.000 claims 3
- 108010054218 Factor VIII Proteins 0.000 claims 3
- 101000851030 Homo sapiens Vascular endothelial growth factor receptor 3 Proteins 0.000 claims 3
- 102100033179 Vascular endothelial growth factor receptor 3 Human genes 0.000 claims 3
- 229960000301 factor viii Drugs 0.000 claims 3
- 210000003494 hepatocyte Anatomy 0.000 claims 3
- 210000000130 stem cell Anatomy 0.000 claims 3
- ZEOWTGPWHLSLOG-UHFFFAOYSA-N Cc1ccc(cc1-c1ccc2c(n[nH]c2c1)-c1cnn(c1)C1CC1)C(=O)Nc1cccc(c1)C(F)(F)F Chemical compound Cc1ccc(cc1-c1ccc2c(n[nH]c2c1)-c1cnn(c1)C1CC1)C(=O)Nc1cccc(c1)C(F)(F)F ZEOWTGPWHLSLOG-UHFFFAOYSA-N 0.000 claims 2
- 102000009024 Epidermal Growth Factor Human genes 0.000 claims 2
- 102000003974 Fibroblast growth factor 2 Human genes 0.000 claims 2
- 108090000379 Fibroblast growth factor 2 Proteins 0.000 claims 2
- 102100023593 Fibroblast growth factor receptor 1 Human genes 0.000 claims 2
- 101710182386 Fibroblast growth factor receptor 1 Proteins 0.000 claims 2
- 102100024616 Platelet endothelial cell adhesion molecule Human genes 0.000 claims 2
- 102100040681 Platelet-derived growth factor C Human genes 0.000 claims 2
- 101710098940 Pro-epidermal growth factor Proteins 0.000 claims 2
- 210000001043 capillary endothelial cell Anatomy 0.000 claims 2
- 238000012258 culturing Methods 0.000 claims 2
- 230000002440 hepatic effect Effects 0.000 claims 2
- 230000033667 organ regeneration Effects 0.000 claims 2
- 108010017992 platelet-derived growth factor C Proteins 0.000 claims 2
- 238000002054 transplantation Methods 0.000 claims 2
- 102000001301 EGF receptor Human genes 0.000 claims 1
- 108060006698 EGF receptor Proteins 0.000 claims 1
- 101150021185 FGF gene Proteins 0.000 claims 1
- 230000006698 induction Effects 0.000 claims 1
- 238000001990 intravenous administration Methods 0.000 claims 1
- 239000003446 ligand Substances 0.000 claims 1
- 230000002685 pulmonary effect Effects 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US41173210P | 2010-11-09 | 2010-11-09 | |
| US61/411,732 | 2010-11-09 | ||
| US201161545851P | 2011-10-11 | 2011-10-11 | |
| US61/545,851 | 2011-10-11 | ||
| PCT/US2011/059960 WO2012064834A2 (en) | 2010-11-09 | 2011-11-09 | Methods for organ regeneration |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017148758A Division JP2018012704A (ja) | 2010-11-09 | 2017-08-01 | 器官再生方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013543760A JP2013543760A (ja) | 2013-12-09 |
| JP2013543760A5 true JP2013543760A5 (cg-RX-API-DMAC7.html) | 2014-12-18 |
| JP6189216B2 JP6189216B2 (ja) | 2017-08-30 |
Family
ID=46051533
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013538845A Active JP6189216B2 (ja) | 2010-11-09 | 2011-11-09 | 器官再生方法 |
| JP2017148758A Pending JP2018012704A (ja) | 2010-11-09 | 2017-08-01 | 器官再生方法 |
| JP2019193924A Pending JP2020023565A (ja) | 2010-11-09 | 2019-10-25 | 器官再生方法 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017148758A Pending JP2018012704A (ja) | 2010-11-09 | 2017-08-01 | 器官再生方法 |
| JP2019193924A Pending JP2020023565A (ja) | 2010-11-09 | 2019-10-25 | 器官再生方法 |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US10946066B2 (cg-RX-API-DMAC7.html) |
| EP (2) | EP3721897B1 (cg-RX-API-DMAC7.html) |
| JP (3) | JP6189216B2 (cg-RX-API-DMAC7.html) |
| AU (3) | AU2011326562B2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2816593C (cg-RX-API-DMAC7.html) |
| DK (1) | DK2637683T3 (cg-RX-API-DMAC7.html) |
| ES (1) | ES2788300T3 (cg-RX-API-DMAC7.html) |
| SG (2) | SG190206A1 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2012064834A2 (cg-RX-API-DMAC7.html) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2816593C (en) * | 2010-11-09 | 2021-05-25 | Shahin Rafii | Methods for organ regeneration |
| AU2013267422B2 (en) | 2012-05-30 | 2018-07-26 | Cornell University | Generation of functional and durable endothelial cells from human amniotic fluid-derived cells |
| JP6076076B2 (ja) * | 2012-12-21 | 2017-02-08 | 日東電工株式会社 | 組織再生促進剤 |
| CN106574243B (zh) | 2014-06-27 | 2021-02-23 | 安吉克莱茵生物科学有限公司 | 表达腺病毒e4orf1的神经细胞及其制备方法和应用 |
| WO2016069897A1 (en) * | 2014-10-30 | 2016-05-06 | Massachusetts Institute Of Technology | Materials and methods for rescue of ischemic tissue and regeneration of tissue integrity during restriction, engraftment and transplantation |
| CA2971439A1 (en) * | 2014-12-19 | 2016-06-23 | Angiocrine Bioscience, Inc. | Biocompatible implants comprising engineered endothelial cells |
| HK1258452A1 (zh) | 2015-07-20 | 2019-11-15 | Angiocrine Bioscience, Inc. | 表达ets转录因子的工程化的内皮细胞 |
| CN105213230A (zh) * | 2015-09-22 | 2016-01-06 | 薇碧生物科技（上海）有限公司 | 一种基于不可见光和酶抑制物来促进胶原蛋白再生的方法 |
| AU2017326174B2 (en) | 2016-09-13 | 2024-02-22 | Angiocrine Bioscience, Inc. | Blood-brain barrier comprising engineered endothelial cells |
| EP3576756A4 (en) | 2017-02-03 | 2020-12-16 | Cornell University | STABLE THREE-DIMENSIONAL BLOOD VESSELS AND THEIR FORMATION PROCESSES |
| US20200155648A1 (en) * | 2017-06-28 | 2020-05-21 | Children's Medical Center Corporation | Promoting lung growth |
| EP4380601A4 (en) * | 2021-08-06 | 2025-06-25 | Trujillo, Charles, Nathan | SYSTEM AND METHOD FOR TREATING OR PREVENTING RESPIRATORY FAILURE WITH AEROSOLIZED COLLAGENASE |
| US12385002B1 (en) * | 2022-01-21 | 2025-08-12 | Sahar M. H. Jaffal | Automated primary cells' triturator |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH06284883A (ja) * | 1992-07-10 | 1994-10-11 | Sanyo Chem Ind Ltd | 肝細胞培養方法 |
| US9585916B2 (en) * | 1999-03-26 | 2017-03-07 | Northern Therapeutics Inc. | Cell based therapy for the pulmonary system |
| WO2002062971A1 (en) | 2001-02-07 | 2002-08-15 | Korea Atomic Energy Research Institute | Method of isolating epithelial cells, method of preconditioning cells, and methods of preparing bioartificial skin and dermis with the epithelial cells or the preconditioned cells |
| IL165392A0 (en) * | 2002-06-05 | 2006-01-15 | Genentech Inc | Compositions and methods for liver growth and liver protection |
| EP1815244A4 (en) | 2004-11-11 | 2009-07-22 | Agency Science Tech & Res | CELL CULTURE DEVICE |
| JP4916159B2 (ja) | 2005-11-09 | 2012-04-11 | 国立大学法人東北大学 | 生体管路ステント |
| US20080176206A1 (en) | 2007-01-18 | 2008-07-24 | Toshiharu Shinoka | Cardiovascular tissue culture substrate |
| WO2008089448A2 (en) * | 2007-01-19 | 2008-07-24 | Cornell Presearch Foundation, Inc. | Methods and compositions for promoting survival & proliferation of endothelial cells & stimulating angiogenesis |
| CN101275121B (zh) * | 2007-03-26 | 2011-05-11 | 芦银雪 | 体外培养扩增的人肝脏祖先细胞及其制备方法 |
| MX2013003522A (es) | 2010-10-01 | 2013-05-22 | Cipla Ltd | Composicion farmaceutica. |
| CA2816593C (en) * | 2010-11-09 | 2021-05-25 | Shahin Rafii | Methods for organ regeneration |
-
2011
- 2011-11-09 CA CA2816593A patent/CA2816593C/en active Active
- 2011-11-09 US US13/884,484 patent/US10946066B2/en active Active
- 2011-11-09 EP EP20160502.9A patent/EP3721897B1/en active Active
- 2011-11-09 EP EP11839627.4A patent/EP2637683B1/en active Active
- 2011-11-09 SG SG2013035381A patent/SG190206A1/en unknown
- 2011-11-09 WO PCT/US2011/059960 patent/WO2012064834A2/en not_active Ceased
- 2011-11-09 AU AU2011326562A patent/AU2011326562B2/en active Active
- 2011-11-09 JP JP2013538845A patent/JP6189216B2/ja active Active
- 2011-11-09 SG SG10201509096SA patent/SG10201509096SA/en unknown
- 2011-11-09 DK DK11839627.4T patent/DK2637683T3/da active
- 2011-11-09 ES ES11839627T patent/ES2788300T3/es active Active
-
2017
- 2017-03-30 AU AU2017202119A patent/AU2017202119B2/en active Active
- 2017-08-01 JP JP2017148758A patent/JP2018012704A/ja active Pending
-
2018
- 2018-12-17 AU AU2018282248A patent/AU2018282248A1/en not_active Abandoned
-
2019
- 2019-10-25 JP JP2019193924A patent/JP2020023565A/ja active Pending
-
2021
- 2021-02-02 US US17/165,286 patent/US20210236598A1/en not_active Abandoned
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