SG10201509096SA - Methods for organ regeneration - Google Patents

Methods for organ regeneration

Info

Publication number
SG10201509096SA
SG10201509096SA SG10201509096SA SG10201509096SA SG10201509096SA SG 10201509096S A SG10201509096S A SG 10201509096SA SG 10201509096S A SG10201509096S A SG 10201509096SA SG 10201509096S A SG10201509096S A SG 10201509096SA SG 10201509096S A SG10201509096S A SG 10201509096SA
Authority
SG
Singapore
Prior art keywords
methods
organ regeneration
regeneration
organ
Prior art date
Application number
SG10201509096SA
Inventor
Shahin Rafii
Bi-Sen Ding
Sina Y Rabbany
Original Assignee
Univ Cornell
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Cornell filed Critical Univ Cornell
Publication of SG10201509096SA publication Critical patent/SG10201509096SA/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/1858—Platelet-derived growth factor [PDGF]
    • A61K38/1866—Vascular endothelial growth factor [VEGF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/44—Vessels; Vascular smooth muscle cells; Endothelial cells; Endothelial progenitor cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/1825—Fibroblast growth factor [FGF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/067—Hepatocytes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2502/00—Coculture with; Conditioned medium produced by
    • C12N2502/28—Vascular endothelial cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Vascular Medicine (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Virology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
SG10201509096SA 2010-11-09 2011-11-09 Methods for organ regeneration SG10201509096SA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US41173210P 2010-11-09 2010-11-09
US201161545851P 2011-10-11 2011-10-11

Publications (1)

Publication Number Publication Date
SG10201509096SA true SG10201509096SA (en) 2015-12-30

Family

ID=46051533

Family Applications (2)

Application Number Title Priority Date Filing Date
SG2013035381A SG190206A1 (en) 2010-11-09 2011-11-09 Methods for organ regeneration
SG10201509096SA SG10201509096SA (en) 2010-11-09 2011-11-09 Methods for organ regeneration

Family Applications Before (1)

Application Number Title Priority Date Filing Date
SG2013035381A SG190206A1 (en) 2010-11-09 2011-11-09 Methods for organ regeneration

Country Status (9)

Country Link
US (2) US10946066B2 (en)
EP (2) EP2637683B1 (en)
JP (3) JP6189216B2 (en)
AU (3) AU2011326562B2 (en)
CA (1) CA2816593C (en)
DK (1) DK2637683T3 (en)
ES (1) ES2788300T3 (en)
SG (2) SG190206A1 (en)
WO (1) WO2012064834A2 (en)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK2637683T3 (en) * 2010-11-09 2020-05-25 Univ Cornell liver regeneration
JP6445971B2 (en) * 2012-05-30 2018-12-26 コーネル ユニヴァーシティー Generation of functional and durable endothelial cells from human amniotic fluid-derived cells
JP6076076B2 (en) * 2012-12-21 2017-02-08 日東電工株式会社 Tissue regeneration promoter
CN106574243B (en) 2014-06-27 2021-02-23 安吉克莱茵生物科学有限公司 Nerve cell for expressing adenovirus E4ORF1 and preparation method and application thereof
US20160121023A1 (en) * 2014-10-30 2016-05-05 Massachusetts Institute Of Technology Materials and Methods for Rescue of Ischemic Tissue and Regeneration of Tissue Integrity During Resection, Engraftment and Transplantation
AU2015364383A1 (en) * 2014-12-19 2017-07-27 Angiocrine Bioscience, Inc. Biocompatible implants comprising engineered endothelial cells
JP6861438B2 (en) 2015-07-20 2021-04-21 アンジオクライン・バイオサイエンス・インコーポレイテッドＡｎｇｉｏｃｒｉｎｅ Ｂｉｏｓｃｉｅｎｃｅ， Ｉｎｃ． Modified endothelial cells expressing ETS transcription factor
CN105213230A (en) * 2015-09-22 2016-01-06 薇碧生物科技（上海）有限公司 A kind of method promoting collagen protein to regenerate based on black light and enzyme inhibitor
EP3512937A4 (en) 2016-09-13 2020-04-15 Angiocrine Bioscience, Inc. Blood-brain barrier comprising engineered endothelial cells
CN110520167B (en) 2017-02-03 2023-03-24 康奈尔大学 Stabilized three-dimensional blood vessels and methods of forming the same
EP3644964B1 (en) * 2017-06-28 2024-04-10 Children's Medical Center Corporation Promoting lung growth
US20230044025A1 (en) * 2021-08-06 2023-02-09 Charles Nathan Trujillo System and method of treating or preventing respiratory failure with aerosolized collagenase

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH06284883A (en) * 1992-07-10 1994-10-11 Sanyo Chem Ind Ltd Hepatocyte cell culture
US9585916B2 (en) * 1999-03-26 2017-03-07 Northern Therapeutics Inc. Cell based therapy for the pulmonary system
WO2002062971A1 (en) 2001-02-07 2002-08-15 Korea Atomic Energy Research Institute Method of isolating epithelial cells, method of preconditioning cells, and methods of preparing bioartificial skin and dermis with the epithelial cells or the preconditioned cells
WO2003103581A2 (en) * 2002-06-05 2003-12-18 Genentech, Inc. Compositions and methods for liver growth and liver protection
US20080233607A1 (en) * 2004-11-11 2008-09-25 Hanry Yu Cell Culture Device
JP4916159B2 (en) * 2005-11-09 2012-04-11 国立大学法人東北大学 Biological duct stent
US20080176206A1 (en) 2007-01-18 2008-07-24 Toshiharu Shinoka Cardiovascular tissue culture substrate
WO2008089448A2 (en) * 2007-01-19 2008-07-24 Cornell Presearch Foundation, Inc. Methods and compositions for promoting survival & proliferation of endothelial cells & stimulating angiogenesis
CN101275121B (en) * 2007-03-26 2011-05-11 芦银雪 In vitro culture-amplified human liver progenitor cell and preparation thereof
KR20140011300A (en) 2010-10-01 2014-01-28 시플라 리미티드 Pharmaceutical composition comprising deferasirox
DK2637683T3 (en) * 2010-11-09 2020-05-25 Univ Cornell liver regeneration

Also Published As

Publication number Publication date
ES2788300T3 (en) 2020-10-21
AU2011326562A1 (en) 2013-06-06
EP2637683A2 (en) 2013-09-18
EP2637683A4 (en) 2015-10-28
DK2637683T3 (en) 2020-05-25
US10946066B2 (en) 2021-03-16
JP2018012704A (en) 2018-01-25
AU2018282248A1 (en) 2019-01-17
US20210236598A1 (en) 2021-08-05
AU2011326562B2 (en) 2017-02-23
SG190206A1 (en) 2013-06-28
WO2012064834A2 (en) 2012-05-18
CA2816593A1 (en) 2012-05-18
AU2017202119A1 (en) 2017-04-20
JP2013543760A (en) 2013-12-09
EP3721897A1 (en) 2020-10-14
EP2637683B1 (en) 2020-03-04
JP2020023565A (en) 2020-02-13
JP6189216B2 (en) 2017-08-30
US20130224161A1 (en) 2013-08-29
CA2816593C (en) 2021-05-25
WO2012064834A3 (en) 2012-07-19
AU2017202119B2 (en) 2019-01-03

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