JP2013542196A - ロパルルス・ジュンセウスサソリの毒由来のペプチド及び医薬組成物 - Google Patents

ロパルルス・ジュンセウスサソリの毒由来のペプチド及び医薬組成物 Download PDF

Info

Publication number
JP2013542196A
JP2013542196A JP2013530559A JP2013530559A JP2013542196A JP 2013542196 A JP2013542196 A JP 2013542196A JP 2013530559 A JP2013530559 A JP 2013530559A JP 2013530559 A JP2013530559 A JP 2013530559A JP 2013542196 A JP2013542196 A JP 2013542196A
Authority
JP
Japan
Prior art keywords
rjlb
venom
peptide
scorpion
scorpion venom
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2013530559A
Other languages
English (en)
Japanese (ja)
Other versions
JP2013542196A5 (OSRAM
Inventor
カストロ,ホセ,アントニオ フラガ
ガリ,レグラ マリア メディナ
ガルシア,アレクシス ディアス
オレラーナ,イラニア ゲバラ
トーレス,カリダード,クララ ロドリゲス
コイペル,フディート ロドリゲス
ガルロボ,ヤネリス リクエネス
マレロ,イスベル ゴンザレス
カポーティ,マリア,レグラ ペレス
Original Assignee
グルポ エンプレサリアル デ プロドゥクシオネス バイオファーマシューティカス イ キミカス
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by グルポ エンプレサリアル デ プロドゥクシオネス バイオファーマシューティカス イ キミカス filed Critical グルポ エンプレサリアル デ プロドゥクシオネス バイオファーマシューティカス イ キミカス
Publication of JP2013542196A publication Critical patent/JP2013542196A/ja
Publication of JP2013542196A5 publication Critical patent/JP2013542196A5/ja
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08Peptides having 5 to 11 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/63Arthropods
    • A61K35/646Arachnids, e.g. spiders, scorpions, ticks or mites
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1767Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/43504Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • C07K14/43513Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from arachnidae
    • C07K14/43522Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from arachnidae from scorpions

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Insects & Arthropods (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
JP2013530559A 2010-09-27 2011-09-27 ロパルルス・ジュンセウスサソリの毒由来のペプチド及び医薬組成物 Pending JP2013542196A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CU2010-0186 2010-09-27
CU2010000186A CU24055B1 (es) 2010-09-27 2010-09-27 Composiciones farmacéuticas de veneno de escorpión rhopalurus junceus
PCT/CU2011/000006 WO2012041261A2 (es) 2010-09-27 2011-09-27 Peptidos del veneno de escorpion rhopalorus junceus y composicion farmaceutica

Publications (2)

Publication Number Publication Date
JP2013542196A true JP2013542196A (ja) 2013-11-21
JP2013542196A5 JP2013542196A5 (OSRAM) 2014-11-13

Family

ID=45566782

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2013530559A Pending JP2013542196A (ja) 2010-09-27 2011-09-27 ロパルルス・ジュンセウスサソリの毒由来のペプチド及び医薬組成物

Country Status (17)

Country Link
EP (1) EP2623111A2 (OSRAM)
JP (1) JP2013542196A (OSRAM)
KR (1) KR20140041381A (OSRAM)
CN (1) CN103200951A (OSRAM)
AP (1) AP2013006811A0 (OSRAM)
AR (1) AR083117A1 (OSRAM)
AU (1) AU2011307691A1 (OSRAM)
BR (1) BR112013007198A2 (OSRAM)
CA (1) CA2812841A1 (OSRAM)
CO (1) CO6781464A2 (OSRAM)
CU (1) CU24055B1 (OSRAM)
EC (1) ECSP13012595A (OSRAM)
IL (1) IL225577A0 (OSRAM)
MX (1) MX360726B (OSRAM)
RU (1) RU2563348C2 (OSRAM)
SG (1) SG191708A1 (OSRAM)
WO (1) WO2012041261A2 (OSRAM)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103074304B (zh) * 2013-01-28 2016-01-13 江苏健安生物科技有限公司 高水平人二倍体细胞培养水痘-带状疱疹疫苗病毒方法
MX2019000570A (es) * 2018-12-19 2020-08-13 Centro De Investig Biologicas Del Noroeste S C Composición homeopatica a base de veneno de escorpión rhopalurus junceus y su uso en acuicultura.
CA3206293A1 (en) * 2020-12-22 2022-06-30 PreveCeutical Medical Inc. Cyclic peptides and uses thereof
CN113384682B (zh) * 2021-05-31 2023-07-04 南方医科大学 蝎毒多肽Smp43在制备抗肿瘤药物的应用
CN117069800B (zh) * 2023-10-16 2023-12-12 山东省食品药品检验研究院 一种鉴别东亚钳蝎的特征多肽及其应用

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1443053A1 (en) * 2001-09-30 2004-08-04 Shenyang Pharmaceutical University Analgesic antitumor peptide from scorpion and method of producing it
US20090123558A1 (en) * 2007-11-13 2009-05-14 Arthur Mikaelian Polarized Scorpion Venom Solution and a Method for Making Polarized Scorpion Venom Solution

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1030229C (zh) 1991-12-16 1995-11-08 山东省蒙阴县酒厂 全蝎酒的制作方法
CN1076858A (zh) 1993-03-24 1993-10-06 王强华 熊胆全蝎酒及其制备工艺
CU22413A1 (es) 1994-01-11 1996-01-31 Composicion antitumoral
US5905027A (en) 1995-12-27 1999-05-18 Uab Research Foundation Method of diagnosing and treating gliomas
FR2745004B1 (fr) * 1996-02-16 1998-03-27 Rhone Poulenc Agrochimie Peptide antibacterien et antifongique
US6168651B1 (en) 1998-10-08 2001-01-02 Donaldson Company, Inc. Filter assembly with shaped adsorbent article; and devices and methods of use
CN1279088A (zh) 1999-06-25 2001-01-10 谷令旗 一种治疗肝癌药剂的制备方法
CN1265901A (zh) 2000-01-26 2000-09-13 徐忠廷 一种抗癌中药丸剂
CN1316249A (zh) 2001-04-04 2001-10-10 李滋星 全蝎活性营养液
CN1157215C (zh) 2001-07-30 2004-07-14 张官锁 一种治疗癌症的中药组合物
CN100465272C (zh) * 2002-01-18 2009-03-04 中国科学院上海有机化学研究所 重组东亚马氏钳蝎毒rBmKaIT1的基因工程
EP2431385A3 (en) * 2002-05-31 2012-07-04 Morphotek, Inc. Combination therapy with chlorotoxin
CN1256971C (zh) 2002-08-12 2006-05-24 徐继康 一种用于治疗肿瘤的中药胶囊

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1443053A1 (en) * 2001-09-30 2004-08-04 Shenyang Pharmaceutical University Analgesic antitumor peptide from scorpion and method of producing it
US20090123558A1 (en) * 2007-11-13 2009-05-14 Arthur Mikaelian Polarized Scorpion Venom Solution and a Method for Making Polarized Scorpion Venom Solution

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
JPN6015043759; B.I.Garcia-Gomez, et al., Toxicon, 2011, 58, pp18-27 *

Also Published As

Publication number Publication date
IL225577A0 (en) 2013-06-27
CN103200951A (zh) 2013-07-10
AR083117A1 (es) 2013-01-30
AP2013006811A0 (en) 2013-04-30
ECSP13012595A (es) 2014-11-28
CU20100186A7 (es) 2012-06-21
KR20140041381A (ko) 2014-04-04
BR112013007198A2 (pt) 2016-06-14
MX2013003545A (es) 2013-11-04
WO2012041261A2 (es) 2012-04-05
RU2013119431A (ru) 2014-11-10
CU24055B1 (es) 2014-12-26
AU2011307691A1 (en) 2013-05-02
EP2623111A2 (en) 2013-08-07
WO2012041261A3 (es) 2012-11-22
CO6781464A2 (es) 2013-10-31
SG191708A1 (en) 2013-08-30
RU2563348C2 (ru) 2015-09-20
CA2812841A1 (en) 2012-04-05
MX360726B (es) 2018-11-13

Similar Documents

Publication Publication Date Title
JP4695839B2 (ja) 神経脳血管障害を治療するための組成物
KR101853254B1 (ko) 펩타이드 및 그의 용도
JP2013542196A (ja) ロパルルス・ジュンセウスサソリの毒由来のペプチド及び医薬組成物
CN110464727B (zh) 3,4-二氢-2h-苯并-[1,4]恶嗪类药物或其盐在制备抑制铁死亡药物中的应用
Al-Sayed et al. Anti-inflammatory, hepatoprotective and antioxidant activity of ellagitannin isolated from Melaleuca styphelioides
CN104788440B (zh) 烟酸衍生物及其应用
Dong et al. Salvianolic acid B ameliorates CNS autoimmunity by suppressing Th1 responses
US20120196892A1 (en) Novel caspase-2 inhibitors
Suganya et al. Anti-gout arthritic activities of ethanolic and zinc oxide nanoparticle extracts of Citrullus colocynthis-An In vitro and Insilico studies
ES2678023T3 (es) Factores extraídos de embriones de pez y uso de mezclas de los mismos en el control de la multiplicación y la diferenciación de células madre
CN112979640B (zh) 一类生物碱二聚体类化合物及其在制备pd-1/pd-l1通路抑制剂中的应用
Chandrappa et al. In vitro anti-inflammatory activity of Carmona retusa (Vahl.)
KR100697236B1 (ko) 오보바톨 또는 오보바탈을 포함하는 항암제 조성물
Moran et al. Insect venoms and their bioactive components: A novel therapeutic approach in chronic diseases and cancer
KR101782962B1 (ko) 백혈병 치료용 조성물 및 몰약 추출물의 제조방법
CA2954781A1 (en) Seaweed extract and composition useful against cancer cells
KR20140012477A (ko) 알로페론을 포함하는 항산화제 안정화 조성물
JP5231244B2 (ja) 胃炎または胃潰瘍の予防及び治療に有用なモクベツシ抽出物及びこれから分離されたモモルディカ・サポニンi
KR20060065770A (ko) 벼 추출물을 포함하는 약학 조성물
KR20050069374A (ko) 암치료 및 예방을 위한 계피 및 대추 추출물
CN100525782C (zh) 具有抗肿瘤作用的扁藻多糖蛋白
Vieira et al. Gastro-protective effects of isobrucein B, a quassinoid isolated from Picrolemma sprucei
Akinlolu et al. ANTI-TOXIC PRINCIPLES FROM MUSA SAPIENTUM AND MORINGA OLEIFERA AMELIORATED SKIN HISTO-PATHOLOGY, DECREASED LIPID PEROXIDATION AND PROMOTED MELATONIN/TNF-ALPHA/P53-MEDIATED APOPTOSIS IN CADMIUM CHLORIDE-INDUCED CARCINOGENESIS IN RATS
Isa Studies on Xanthine Oxidase Inhibitory Activity of Plumeria Rubra Linn Flower
Prasanna et al. In vitro anti-inflammatory activity of Drynaria quercifolia rhizome

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20140929

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20140929

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20151104

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20160328