JP2013541587A - Nedd8活性化酵素阻害剤の投与 - Google Patents
Nedd8活性化酵素阻害剤の投与 Download PDFInfo
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- JP2013541587A JP2013541587A JP2013537807A JP2013537807A JP2013541587A JP 2013541587 A JP2013541587 A JP 2013541587A JP 2013537807 A JP2013537807 A JP 2013537807A JP 2013537807 A JP2013537807 A JP 2013537807A JP 2013541587 A JP2013541587 A JP 2013541587A
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Applications Claiming Priority (5)
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| US41047810P | 2010-11-05 | 2010-11-05 | |
| US61/410,478 | 2010-11-05 | ||
| US201161488240P | 2011-05-20 | 2011-05-20 | |
| US61/488,240 | 2011-05-20 | ||
| PCT/US2011/059060 WO2012061551A1 (en) | 2010-11-05 | 2011-11-03 | Administration of nedd8-activating enzyme inhibitor |
Publications (2)
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| JP2013541587A true JP2013541587A (ja) | 2013-11-14 |
| JP2013541587A5 JP2013541587A5 (enExample) | 2014-12-18 |
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| JP2013537807A Pending JP2013541587A (ja) | 2010-11-05 | 2011-11-03 | Nedd8活性化酵素阻害剤の投与 |
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| US (2) | US20120115892A1 (enExample) |
| EP (1) | EP2635287A4 (enExample) |
| JP (1) | JP2013541587A (enExample) |
| WO (1) | WO2012061551A1 (enExample) |
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| WO2017111074A1 (ja) * | 2015-12-22 | 2017-06-29 | 大鵬薬品工業株式会社 | ピロロピリミジン化合物による抗腫瘍効果増強剤 |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2013188881A1 (en) * | 2012-06-15 | 2013-12-19 | President And Fellows Of Harvard College | Compounds, compositions and methods for treating or preventing neurodegenerative disorders |
| US9200333B2 (en) | 2012-07-25 | 2015-12-01 | Indiana University Research And Technology Corporation | Methods for identifying modulators of murine double minute 2 |
| JP6556701B2 (ja) * | 2013-05-14 | 2019-08-07 | ミレニアム ファーマシューティカルズ, インコーポレイテッドMillennium Pharmaceuticals, Inc. | Nedd8活性化酵素阻害剤及び化学療法剤の投与 |
| EP3103802B1 (en) | 2014-06-24 | 2017-11-08 | Taiho Pharmaceutical Co., Ltd. | Novel pyrrolopyrimidine compound or salt thereof, pharmaceutical composition containing same, especially agent for prevention and/or treatment of tumors etc based on nae inhibitory effect |
| CN108210497B (zh) * | 2016-12-21 | 2019-12-20 | 天津大学 | 化合物mln4924在制备布尼亚病毒科白蛉病毒属病毒抑制剂的应用 |
| WO2020176643A1 (en) * | 2019-02-26 | 2020-09-03 | Millennium Pharmaceuticals, Inc. | Compounds useful as adjuvants |
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| WO2009038701A2 (en) * | 2007-09-17 | 2009-03-26 | Schering Corporation | Formulation containing cyclin-dependent kinase inhibiting compound and method of treating tumors using the same |
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| KR101450533B1 (ko) * | 2006-02-02 | 2014-10-16 | 밀레니엄 파머슈티컬스 인코퍼레이티드 | E1 활성화 효소의 억제제 |
| KR20100066475A (ko) * | 2007-08-02 | 2010-06-17 | 밀레니엄 파머슈티컬스 인코퍼레이티드 | E1 활성화 효소 억제제의 합성 방법 |
| KR20120024715A (ko) * | 2009-05-14 | 2012-03-14 | 밀레니엄 파머슈티컬스 인코퍼레이티드 | ((1s,2s,4r)?4?{4?〔(1s)?2,3?디하이드로?1h?인덴?1?일아미노〕?7h?피롤로〔2,3?d〕피리미딘?7?일}?2?하이드록시사이클로펜틸)메틸 설파메이트의 하이드로클로라이드 염 |
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2011
- 2011-11-03 US US13/288,146 patent/US20120115892A1/en not_active Abandoned
- 2011-11-03 WO PCT/US2011/059060 patent/WO2012061551A1/en not_active Ceased
- 2011-11-03 JP JP2013537807A patent/JP2013541587A/ja active Pending
- 2011-11-03 EP EP11838783.6A patent/EP2635287A4/en not_active Withdrawn
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2013
- 2013-10-08 US US14/048,854 patent/US20140249167A1/en not_active Abandoned
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| WO2009038701A2 (en) * | 2007-09-17 | 2009-03-26 | Schering Corporation | Formulation containing cyclin-dependent kinase inhibiting compound and method of treating tumors using the same |
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| JPN7015002695; 'View of NCT01011530 on 2010_10_18' ClinicalTrials.gov archive , 20101018 * |
| JPN7015002696; SHAH, Jatin J et al: 'Phase 1 Dose-Escalation Study of MLN4924, a Novel NAE Inhibitor, in Patients with Multiple Myeloma a' 51th ASH ANNUAL MEETING AND EXPOSITION , 20091203 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2017111074A1 (ja) * | 2015-12-22 | 2017-06-29 | 大鵬薬品工業株式会社 | ピロロピリミジン化合物による抗腫瘍効果増強剤 |
| JPWO2017111074A1 (ja) * | 2015-12-22 | 2018-05-10 | 大鵬薬品工業株式会社 | ピロロピリミジン化合物による抗腫瘍効果増強剤 |
Also Published As
| Publication number | Publication date |
|---|---|
| US20120115892A1 (en) | 2012-05-10 |
| US20140249167A1 (en) | 2014-09-04 |
| WO2012061551A1 (en) | 2012-05-10 |
| EP2635287A1 (en) | 2013-09-11 |
| EP2635287A4 (en) | 2014-06-04 |
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