JP2013532130A5 - - Google Patents
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- JP2013532130A5 JP2013532130A5 JP2013510364A JP2013510364A JP2013532130A5 JP 2013532130 A5 JP2013532130 A5 JP 2013532130A5 JP 2013510364 A JP2013510364 A JP 2013510364A JP 2013510364 A JP2013510364 A JP 2013510364A JP 2013532130 A5 JP2013532130 A5 JP 2013532130A5
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- represented
- compound
- pharmaceutically acceptable
- acceptable salt
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Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US33499110P | 2010-05-14 | 2010-05-14 | |
| US61/334,991 | 2010-05-14 | ||
| US37074510P | 2010-08-04 | 2010-08-04 | |
| US61/370,745 | 2010-08-04 | ||
| US37586310P | 2010-08-22 | 2010-08-22 | |
| US61/375,863 | 2010-08-22 | ||
| PCT/US2011/036701 WO2011143669A2 (en) | 2010-05-14 | 2011-05-16 | Compositions and methods for treating neoplasia, inflammatory disease and other disorders |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015049960A Division JP5937247B2 (ja) | 2010-05-14 | 2015-03-12 | 新生物、炎症性疾患、およびその他の障害を治療するための組成物および方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013532130A JP2013532130A (ja) | 2013-08-15 |
| JP2013532130A5 true JP2013532130A5 (ko) | 2014-11-06 |
| JP5715241B2 JP5715241B2 (ja) | 2015-05-07 |
Family
ID=49052897
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013510364A Active JP5715241B2 (ja) | 2010-05-14 | 2011-05-16 | 新生物、炎症性疾患、およびその他の障害を治療するための組成物および方法 |
| JP2015049960A Active JP5937247B2 (ja) | 2010-05-14 | 2015-03-12 | 新生物、炎症性疾患、およびその他の障害を治療するための組成物および方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015049960A Active JP5937247B2 (ja) | 2010-05-14 | 2015-03-12 | 新生物、炎症性疾患、およびその他の障害を治療するための組成物および方法 |
Country Status (1)
| Country | Link |
|---|---|
| JP (2) | JP5715241B2 (ko) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK2571503T3 (en) | 2010-05-14 | 2015-04-20 | Dana Farber Cancer Inst Inc | COMPOSITIONS AND THEIR USE IN THE TREATMENT OF NEOPLASIA, INFLAMMATORY DISEASE AND OTHER DISORDERS |
| CN103119160B (zh) * | 2010-05-14 | 2016-06-01 | 达那-法伯癌症研究所 | 用于调节代谢的组合物和方法 |
| IN2014DN11269A (ko) * | 2012-06-25 | 2015-10-09 | Oncoethix Sa | |
| US20160158246A1 (en) * | 2013-08-06 | 2016-06-09 | Oncoethix Gmbh | Method of treating diffuse large b-cell lymphoma (dlbcl) using a bet-bromodomain inhibitor |
| RU2016122654A (ru) | 2013-11-08 | 2017-12-14 | Дана-Фарбер Кэнсер Инститьют, Инк. | Комбинированная терапия злокачественной опухоли с использованием ингибиторов бромодоменового и экстратерминального (вет) белка |
| CN106456653A (zh) | 2014-02-28 | 2017-02-22 | 腾沙治疗公司 | 高胰岛素血症相关病症的治疗 |
| EP3314005A1 (en) * | 2015-06-26 | 2018-05-02 | Tensha Therapeutics, Inc. | Treatment of nut midline carcinoma |
| AU2016319116B2 (en) * | 2015-09-11 | 2020-10-01 | Dana-Farber Cancer Institute, Inc. | Cyano thienotriazolodiazepines and uses thereof |
| SG10202007099TA (en) * | 2015-09-11 | 2020-08-28 | Dana Farber Cancer Inst Inc | Acetamide thienotriazoldiazepines and uses thereof |
| CN108289957A (zh) * | 2015-10-02 | 2018-07-17 | 达纳-法伯癌症研究所股份有限公司 | 溴区结构域抑制剂和检查点阻断的组合疗法 |
| ES2882066T3 (es) * | 2016-02-15 | 2021-12-01 | Univ Michigan Regents | 1,4-oxazepinas fusionadas y análogos relacionados como inhibidores de bromodominio BET |
| BR112019008435A2 (pt) * | 2016-12-16 | 2019-07-09 | Hoffmann La Roche | processos para a preparação de um composto de fórmula, processo para a fabricação de um composto de fórmula, processos para a purificação de um composto de fórmula, composto e presente invenção |
| CN109503618A (zh) * | 2017-09-14 | 2019-03-22 | 成都海创药业有限公司 | 一种brd4抑制剂 |
| BR112020025003A2 (pt) * | 2018-06-13 | 2021-03-23 | Dybly Ag | preparação de derivados de triazepina condensados e uso dos mesmos como inibidores de bet |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1227555A (zh) * | 1996-06-12 | 1999-09-01 | 日本烟草产业株式会社 | 细胞因子生成抑制剂、三氮䓬化合物及其中间体 |
| US7589167B2 (en) * | 2000-02-22 | 2009-09-15 | J. David Gladstone Institutes | ZA loops of bromodomains |
| AU2004215359A1 (en) * | 2003-02-27 | 2004-09-10 | Abbott Laboratories | Heterocyclic kinase inhibitors |
| JP5478262B2 (ja) * | 2007-12-28 | 2014-04-23 | 田辺三菱製薬株式会社 | 抗癌剤 |
| KR20120097508A (ko) * | 2009-11-05 | 2012-09-04 | 글락소스미스클라인 엘엘씨 | 벤조디아제핀 브로모도메인 억제제 |
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2011
- 2011-05-16 JP JP2013510364A patent/JP5715241B2/ja active Active
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2015
- 2015-03-12 JP JP2015049960A patent/JP5937247B2/ja active Active