JP2013528586A5 - - Google Patents
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- Publication number
- JP2013528586A5 JP2013528586A5 JP2013508577A JP2013508577A JP2013528586A5 JP 2013528586 A5 JP2013528586 A5 JP 2013528586A5 JP 2013508577 A JP2013508577 A JP 2013508577A JP 2013508577 A JP2013508577 A JP 2013508577A JP 2013528586 A5 JP2013528586 A5 JP 2013528586A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- organic peroxide
- sample
- mono
- optionally
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000000034 method Methods 0.000 claims 28
- 125000000217 alkyl group Chemical group 0.000 claims 27
- 150000001451 organic peroxides Chemical class 0.000 claims 22
- 229910052799 carbon Inorganic materials 0.000 claims 19
- 229910052739 hydrogen Inorganic materials 0.000 claims 18
- 244000005700 microbiome Species 0.000 claims 7
- 125000004123 n-propyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])* 0.000 claims 6
- -1 C 1-6 -alkoxy Chemical group 0.000 claims 5
- 125000000882 C2-C6 alkenyl group Chemical group 0.000 claims 5
- 125000003320 C2-C6 alkenyloxy group Chemical group 0.000 claims 5
- 241000700605 Viruses Species 0.000 claims 5
- 125000000304 alkynyl group Chemical group 0.000 claims 5
- 125000003118 aryl group Chemical group 0.000 claims 5
- 125000003917 carbamoyl group Chemical group [H]N([H])C(*)=O 0.000 claims 5
- 125000001072 heteroaryl group Chemical group 0.000 claims 5
- 125000000592 heterocycloalkyl group Chemical group 0.000 claims 5
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 claims 5
- 102000039446 nucleic acids Human genes 0.000 claims 4
- 108020004707 nucleic acids Proteins 0.000 claims 4
- 150000007523 nucleic acids Chemical class 0.000 claims 4
- 238000004113 cell culture Methods 0.000 claims 3
- 238000004519 manufacturing process Methods 0.000 claims 3
- 239000000203 mixture Substances 0.000 claims 3
- 239000008194 pharmaceutical composition Substances 0.000 claims 3
- 125000006563 (C1-3) alkylaminocarbonyl group Chemical group 0.000 claims 2
- 125000006603 (C1-C3) alkylaminosulfonyl group Chemical group 0.000 claims 2
- 125000004454 (C1-C6) alkoxycarbonyl group Chemical group 0.000 claims 2
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 claims 2
- 125000004390 alkyl sulfonyl group Chemical group 0.000 claims 2
- 125000002947 alkylene group Chemical group 0.000 claims 2
- 125000002915 carbonyl group Chemical group [*:2]C([*:1])=O 0.000 claims 2
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 claims 2
- 239000003638 chemical reducing agent Substances 0.000 claims 2
- 125000004093 cyano group Chemical group *C#N 0.000 claims 2
- 239000003814 drug Substances 0.000 claims 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims 2
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 claims 2
- 150000002978 peroxides Chemical group 0.000 claims 2
- 229960005486 vaccine Drugs 0.000 claims 2
- XYFYIMMQLFFGKB-UHFFFAOYSA-N 1,1,5,5-tetrahydroperoxypentane Chemical compound OOC(OO)CCCC(OO)OO XYFYIMMQLFFGKB-UHFFFAOYSA-N 0.000 claims 1
- KVFLZSZJBRWQJK-UHFFFAOYSA-N 1,1-dihydroperoxyethane Chemical compound OOC(C)OO KVFLZSZJBRWQJK-UHFFFAOYSA-N 0.000 claims 1
- LPZSIYDMHWOREJ-UHFFFAOYSA-N 1,1-dihydroperoxypropane Chemical compound CCC(OO)OO LPZSIYDMHWOREJ-UHFFFAOYSA-N 0.000 claims 1
- GIHSGBFMYFAEDX-UHFFFAOYSA-N 2,2-dihydroperoxybutane Chemical compound CCC(C)(OO)OO GIHSGBFMYFAEDX-UHFFFAOYSA-N 0.000 claims 1
- KJTGWWIZKOWELB-UHFFFAOYSA-N 3,7-dihydroperoxydioxepane Chemical compound OOC1CCCC(OO)OO1 KJTGWWIZKOWELB-UHFFFAOYSA-N 0.000 claims 1
- TVEXGJYMHHTVKP-UHFFFAOYSA-N 6-oxabicyclo[3.2.1]oct-3-en-7-one Chemical compound C1C2C(=O)OC1C=CC2 TVEXGJYMHHTVKP-UHFFFAOYSA-N 0.000 claims 1
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 claims 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims 1
- 241000712431 Influenza A virus Species 0.000 claims 1
- 241000713196 Influenza B virus Species 0.000 claims 1
- 241000713297 Influenza C virus Species 0.000 claims 1
- 241000711798 Rabies lyssavirus Species 0.000 claims 1
- 102000007056 Recombinant Fusion Proteins Human genes 0.000 claims 1
- 108010008281 Recombinant Fusion Proteins Proteins 0.000 claims 1
- 229940100198 alkylating agent Drugs 0.000 claims 1
- 239000002168 alkylating agent Substances 0.000 claims 1
- 229960005070 ascorbic acid Drugs 0.000 claims 1
- 235000010323 ascorbic acid Nutrition 0.000 claims 1
- 239000011668 ascorbic acid Substances 0.000 claims 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 claims 1
- 239000007795 chemical reaction product Substances 0.000 claims 1
- 150000001875 compounds Chemical class 0.000 claims 1
- 239000000356 contaminant Substances 0.000 claims 1
- 239000000032 diagnostic agent Substances 0.000 claims 1
- 229940039227 diagnostic agent Drugs 0.000 claims 1
- GOQBCAPQQJUCOC-UHFFFAOYSA-N dihydroperoxymethane Chemical compound OOCOO GOQBCAPQQJUCOC-UHFFFAOYSA-N 0.000 claims 1
- 229910052736 halogen Inorganic materials 0.000 claims 1
- 150000002367 halogens Chemical class 0.000 claims 1
- 239000001257 hydrogen Substances 0.000 claims 1
- 230000000415 inactivating effect Effects 0.000 claims 1
- 230000002779 inactivation Effects 0.000 claims 1
- 239000000463 material Substances 0.000 claims 1
- 229910052760 oxygen Inorganic materials 0.000 claims 1
- 239000001301 oxygen Substances 0.000 claims 1
- 239000000047 product Substances 0.000 claims 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US39511710P | 2010-05-06 | 2010-05-06 | |
| US61/395,117 | 2010-05-06 | ||
| PCT/IB2011/001394 WO2011138682A2 (en) | 2010-05-06 | 2011-05-06 | Organic peroxide compounds for microorganism inactivation |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013528586A JP2013528586A (ja) | 2013-07-11 |
| JP2013528586A5 true JP2013528586A5 (https=) | 2015-04-16 |
| JP6072677B2 JP6072677B2 (ja) | 2017-02-01 |
Family
ID=44532956
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013508577A Expired - Fee Related JP6072677B2 (ja) | 2010-05-06 | 2011-05-06 | 微生物の不活化のための有機ペルオキシド化合物 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US9426989B2 (https=) |
| EP (1) | EP2566323A2 (https=) |
| JP (1) | JP6072677B2 (https=) |
| KR (1) | KR20130079398A (https=) |
| CN (1) | CN102946727B (https=) |
| AU (1) | AU2011249487C1 (https=) |
| BR (1) | BR112012028146A2 (https=) |
| CA (1) | CA2796213A1 (https=) |
| EA (1) | EA201291179A1 (https=) |
| MX (1) | MX343948B (https=) |
| WO (1) | WO2011138682A2 (https=) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8883848B2 (en) | 2011-07-14 | 2014-11-11 | Ecolab Usa Inc. | Enhanced microbial peracid compositions and methods of use at reduced temperatures in aseptic cleaning |
| US8906963B2 (en) | 2011-07-14 | 2014-12-09 | Ecolab Usa Inc | Deodorization of peracids |
| GB2495341B (en) | 2011-11-11 | 2013-09-18 | Novartis Ag | Fermentation methods and their products |
| ITUA20162517A1 (it) * | 2016-04-12 | 2017-10-12 | Andrea Fantozzi | Composizione per la conservazione/fissazione di materiale biologico |
| MX2020004151A (es) | 2017-10-30 | 2020-08-13 | Takeda Pharmaceuticals Co | Detergentes compatibles con el medio ambiente para la inactivacion de virus envueltos en lipidos. |
| CN110804641A (zh) * | 2019-09-04 | 2020-02-18 | 中国农业科学院兰州兽医研究所 | 一种比较分析不同牛支原体菌株毒力的方法 |
| MX2022005513A (es) | 2019-11-07 | 2022-06-08 | Seqirus Uk Ltd | Composiciones y metodos para producir una vacuna viral con tama?o de particula reducido. |
Family Cites Families (44)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL288026A (https=) * | 1963-01-16 | |||
| US3560395A (en) * | 1968-09-12 | 1971-02-02 | Pennwalt Corp | Aqueous ketone peroxide-hydrogen peroxide composition |
| US4060644A (en) * | 1976-02-09 | 1977-11-29 | Interox Chemicals Limited | Bleaching |
| DE2933498A1 (de) * | 1979-08-18 | 1981-04-09 | Dr.rer.nat. Hans-Dieter 4234 Alpen Deppe | Chemothermisches desinfektions- und sterilisationsverfahren |
| PH25669A (en) * | 1985-12-19 | 1991-09-04 | Padmini Sampathkumar | Anaerobe-selective antibacterial compositions, methods |
| EP0461700A1 (en) * | 1990-06-12 | 1991-12-18 | Akzo Nobel N.V. | Aqueous disinfectant compositions, and concentrates for preparing the same |
| US5437868A (en) * | 1991-07-23 | 1995-08-01 | Ecolab Inc. | Peroxyacid antimicrobial composition |
| GB9222561D0 (en) | 1992-10-27 | 1992-12-09 | Ici Plc | Macromolecular degradation |
| US5824536A (en) * | 1994-08-23 | 1998-10-20 | St. Jude Children's Research Hospital | Influenza virus replicated in mammalian cell culture and vaccine production |
| FR2738127B1 (fr) | 1995-08-30 | 1998-03-27 | Oreal | Applicateur de mascara |
| DE19612966B4 (de) | 1996-04-01 | 2009-12-10 | Novartis Vaccines And Diagnostics Gmbh & Co. Kg | MDCK-Zellen und Verfahren zur Vermehrung von Influenzaviren |
| GB9612035D0 (en) * | 1996-06-08 | 1996-08-07 | Oilfield Chemical Additives Li | Method of inhibiting reservoir souring by bacteria |
| DE19817743A1 (de) * | 1998-04-21 | 1999-10-28 | Binker Materialschutz Gmbh | Materialschutzmittel |
| AU758625B2 (en) * | 1998-08-20 | 2003-03-27 | Ecolab Inc. | The treatment of meat products |
| TR200200776T2 (tr) | 1999-09-24 | 2002-06-21 | Smithkline Beecham Biologicals S.A. | Burun içi grip virüsü aşısı. |
| JP4698112B2 (ja) | 2000-03-03 | 2011-06-08 | 一般財団法人化学及血清療法研究所 | 無血清培養かつ浮遊培養可能な細胞及び当該細胞を用いたワクチン用ウイルスの製造法 |
| FR2808803B1 (fr) | 2000-05-11 | 2004-12-10 | Agronomique Inst Nat Rech | Cellules es modifiees et gene specifique de cellules es |
| GB0024089D0 (en) | 2000-10-02 | 2000-11-15 | Smithkline Beecham Biolog | Novel compounds |
| US20020107288A1 (en) * | 2000-12-08 | 2002-08-08 | Singh Waheguru Pal | Methods of sterilizing with dipercarboxylic acids |
| US7316824B2 (en) * | 2000-12-15 | 2008-01-08 | Ecolab Inc. | Method and composition for washing poultry during processing |
| ATE503493T1 (de) | 2001-02-23 | 2011-04-15 | Glaxosmithkline Biolog Sa | Influenza vakzinzusammensetzungen zur intradermaler verabreichung |
| JP2004536785A (ja) | 2001-02-23 | 2004-12-09 | グラクソスミスクライン バイオロジカルズ ソシエテ アノニム | 新規なワクチン |
| TWI228420B (en) | 2001-05-30 | 2005-03-01 | Smithkline Beecham Pharma Gmbh | Novel vaccine composition |
| US20030012804A1 (en) * | 2001-06-22 | 2003-01-16 | Aquacide And Use | Aquacide and use |
| JPWO2003014338A1 (ja) * | 2001-08-02 | 2004-11-25 | アンジェスＭｇ株式会社 | 不活性化ウイルスエンベロープの製造方法 |
| DE10144906B4 (de) | 2001-09-12 | 2013-11-28 | Novartis Vaccines And Diagnostics Gmbh | Verfahren zur großtechnischen Herstellung von Impfstoffen |
| DE10144903A1 (de) | 2001-09-12 | 2003-03-27 | Chiron Behring Gmbh & Co | Vermehrung von Viren in Zellkultur |
| FR2832423B1 (fr) | 2001-11-22 | 2004-10-08 | Vivalis | Systeme d'expression de proteines exogenes dans un systeme aviaire |
| CN1194984C (zh) * | 2002-02-04 | 2005-03-30 | 中国农业科学院植物保护研究所 | 一种抗生素及其制备方法和应用 |
| FR2836924B1 (fr) | 2002-03-08 | 2005-01-14 | Vivalis | Lignees de cellules aviaires utiles pour la production de substances d'interet |
| JP4299514B2 (ja) * | 2002-08-29 | 2009-07-22 | 長谷川香料株式会社 | 抗菌抗カビ剤 |
| DE10306018A1 (de) * | 2003-02-13 | 2004-09-09 | Siemens Ag | Analyse- und Diagnostikinstrument |
| JP2006523657A (ja) * | 2003-04-16 | 2006-10-19 | ネオケミカル デザロージョス アバンサードス，ソシエダ アノニマ | 殺生物剤：殺菌剤、防腐剤、消毒剤及び駆虫剤としてのジアルキルケトンペルオキシドの使用 |
| EP1528101A1 (en) | 2003-11-03 | 2005-05-04 | ProBioGen AG | Immortalized avian cell lines for virus production |
| WO2005113756A1 (en) | 2004-05-14 | 2005-12-01 | Glaxosmithkline Biologicals S.A. | Method |
| NZ551640A (en) | 2004-05-20 | 2010-05-28 | Id Biomedical Corp | Process for the production of an influenza vaccine |
| ATE547511T1 (de) | 2004-12-23 | 2012-03-15 | Medimmune Llc | Nichttumorbildende mdck-zellinie zur vermehrung von viren |
| GB0505909D0 (en) | 2005-03-23 | 2005-04-27 | Univ Leeds | Formulations |
| FR2884255B1 (fr) | 2005-04-11 | 2010-11-05 | Vivalis | Utilisation de lignees de cellules souches aviaires ebx pour la production de vaccin contre la grippe |
| CA2618306C (en) * | 2005-08-08 | 2014-10-21 | Oregon Health & Science University | Inactivating pathogens with hydrogen peroxide for vaccine production |
| WO2007042175A1 (en) * | 2005-10-07 | 2007-04-19 | Dsm Ip Assets B.V. | Peroxide decomposition catalyst |
| CA2627971A1 (en) | 2005-11-01 | 2007-05-10 | Novartis Vaccines And Diagnostics Gmbh & Co Kg. | Cell-derived viral vaccines with low levels of residual cell dna by beta-propiolactone treatment |
| ES2286949B1 (es) * | 2006-05-26 | 2008-11-01 | Braulio Peña Rodriguez | Uso de combinaciones de peroxido de metil etil cetona por pulverizacion. |
| SG177141A1 (en) | 2006-12-06 | 2012-01-30 | Novartis Ag | Vaccines including antigen from four strains of influenza virus |
-
2011
- 2011-05-06 WO PCT/IB2011/001394 patent/WO2011138682A2/en not_active Ceased
- 2011-05-06 CN CN201180022567.3A patent/CN102946727B/zh not_active Expired - Fee Related
- 2011-05-06 KR KR1020127030049A patent/KR20130079398A/ko not_active Withdrawn
- 2011-05-06 MX MX2012012335A patent/MX343948B/es active IP Right Grant
- 2011-05-06 JP JP2013508577A patent/JP6072677B2/ja not_active Expired - Fee Related
- 2011-05-06 CA CA2796213A patent/CA2796213A1/en not_active Abandoned
- 2011-05-06 EP EP11733909A patent/EP2566323A2/en not_active Withdrawn
- 2011-05-06 AU AU2011249487A patent/AU2011249487C1/en not_active Ceased
- 2011-05-06 US US13/696,595 patent/US9426989B2/en not_active Expired - Fee Related
- 2011-05-06 EA EA201291179A patent/EA201291179A1/ru unknown
- 2011-05-06 BR BR112012028146A patent/BR112012028146A2/pt not_active IP Right Cessation
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