JP2013526572A5 - - Google Patents
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- Publication number
- JP2013526572A5 JP2013526572A5 JP2013511293A JP2013511293A JP2013526572A5 JP 2013526572 A5 JP2013526572 A5 JP 2013526572A5 JP 2013511293 A JP2013511293 A JP 2013511293A JP 2013511293 A JP2013511293 A JP 2013511293A JP 2013526572 A5 JP2013526572 A5 JP 2013526572A5
- Authority
- JP
- Japan
- Prior art keywords
- polymer compound
- vinyl acetate
- eye
- ethylene
- compound part
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 150000001875 compounds Chemical class 0.000 claims 24
- 229920000642 polymer Polymers 0.000 claims 21
- DQXBYHZEEUGOBF-UHFFFAOYSA-N but-3-enoic acid;ethene Chemical compound C=C.OC(=O)CC=C DQXBYHZEEUGOBF-UHFFFAOYSA-N 0.000 claims 6
- 239000005038 ethylene vinyl acetate Substances 0.000 claims 6
- 229920001200 poly(ethylene-vinyl acetate) Polymers 0.000 claims 6
- 239000013543 active substance Substances 0.000 claims 5
- 229920003176 water-insoluble polymer Polymers 0.000 claims 4
- XTXRWKRVRITETP-UHFFFAOYSA-N Vinyl acetate Chemical compound CC(=O)OC=C XTXRWKRVRITETP-UHFFFAOYSA-N 0.000 claims 3
- 229920000219 Ethylene vinyl alcohol Polymers 0.000 claims 2
- 210000000795 conjunctiva Anatomy 0.000 claims 2
- 239000004715 ethylene vinyl alcohol Substances 0.000 claims 2
- RZXDTJIXPSCHCI-UHFFFAOYSA-N hexa-1,5-diene-2,5-diol Chemical compound OC(=C)CCC(O)=C RZXDTJIXPSCHCI-UHFFFAOYSA-N 0.000 claims 2
- HNPFPERDNWXAGS-NFVOFSAMSA-N latanoprost free acid Chemical class C([C@@H](O)CCC=1C=CC=CC=1)C[C@H]1[C@H](O)C[C@H](O)[C@@H]1C\C=C/CCCC(O)=O HNPFPERDNWXAGS-NFVOFSAMSA-N 0.000 claims 2
- IMROMDMJAWUWLK-UHFFFAOYSA-N Ethenol Chemical compound OC=C IMROMDMJAWUWLK-UHFFFAOYSA-N 0.000 claims 1
- KIQXRQVVYTYYAZ-MTNCBHNASA-N Tafluprost free acid Chemical class OC(=O)CCC\C=C/CC1C(O)CC(O)C1\C=C\C(F)(F)COC1=CC=CC=C1 KIQXRQVVYTYYAZ-MTNCBHNASA-N 0.000 claims 1
- 239000002253 acid Substances 0.000 claims 1
- 125000000637 arginyl group Chemical class N[C@@H](CCCNC(N)=N)C(=O)* 0.000 claims 1
- 229960002470 bimatoprost Drugs 0.000 claims 1
- AQOKCDNYWBIDND-FTOWTWDKSA-N bimatoprost Chemical compound CCNC(=O)CCC\C=C/C[C@H]1[C@@H](O)C[C@@H](O)[C@@H]1\C=C\[C@@H](O)CCC1=CC=CC=C1 AQOKCDNYWBIDND-FTOWTWDKSA-N 0.000 claims 1
- 238000010828 elution Methods 0.000 claims 1
- WWSWYXNVCBLWNZ-QIZQQNKQSA-N fluprostenol Chemical class C([C@H](O)\C=C\[C@@H]1[C@H]([C@@H](O)C[C@H]1O)C\C=C/CCCC(O)=O)OC1=CC=CC(C(F)(F)F)=C1 WWSWYXNVCBLWNZ-QIZQQNKQSA-N 0.000 claims 1
- 230000037431 insertion Effects 0.000 claims 1
- 238000003780 insertion Methods 0.000 claims 1
- 229960001160 latanoprost Drugs 0.000 claims 1
- GGXICVAJURFBLW-CEYXHVGTSA-N latanoprost Chemical compound CC(C)OC(=O)CCC\C=C/C[C@H]1[C@@H](O)C[C@@H](O)[C@@H]1CC[C@@H](O)CCC1=CC=CC=C1 GGXICVAJURFBLW-CEYXHVGTSA-N 0.000 claims 1
- 239000011159 matrix material Substances 0.000 claims 1
- 150000003839 salts Chemical class 0.000 claims 1
- 210000003786 sclera Anatomy 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US34554710P | 2010-05-17 | 2010-05-17 | |
| US61/345,547 | 2010-05-17 | ||
| PCT/US2011/036806 WO2011146483A1 (en) | 2010-05-17 | 2011-05-17 | Drug delivery devices for delivery of ocular therapeutic agents |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2013526572A JP2013526572A (ja) | 2013-06-24 |
| JP2013526572A5 true JP2013526572A5 (https=) | 2014-07-03 |
Family
ID=44992020
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013511293A Pending JP2013526572A (ja) | 2010-05-17 | 2011-05-17 | 眼治療薬の送達のための薬物送達装置 |
Country Status (6)
| Country | Link |
|---|---|
| US (6) | US20130142858A1 (https=) |
| EP (1) | EP2571526B1 (https=) |
| JP (1) | JP2013526572A (https=) |
| AU (1) | AU2011256259A1 (https=) |
| CA (1) | CA2798084A1 (https=) |
| WO (1) | WO2011146483A1 (https=) |
Families Citing this family (42)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
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| EP2432420A4 (en) | 2009-05-18 | 2018-01-10 | Dose Medical Corporation | Drug eluting ocular implant |
| US12478503B2 (en) | 2009-05-18 | 2025-11-25 | Glaukos Corporation | Implants with controlled drug delivery features and methods of using same |
| EP2437684B1 (en) | 2009-06-03 | 2022-06-15 | ForSight Vision5, Inc. | Anterior segment drug delivery |
| EP2571526B1 (en) | 2010-05-17 | 2019-03-13 | Novaer Holdings, Inc. | Drug delivery devices for delivery of ocular therapeutic agents |
| EP2654715B1 (en) | 2010-11-24 | 2017-01-25 | Dose Medical Corporation | Drug eluting ocular implant |
| US10245178B1 (en) | 2011-06-07 | 2019-04-02 | Glaukos Corporation | Anterior chamber drug-eluting ocular implant |
| US9873765B2 (en) | 2011-06-23 | 2018-01-23 | Dsm Ip Assets, B.V. | Biodegradable polyesteramide copolymers for drug delivery |
| ES2992024T3 (es) | 2011-06-23 | 2024-12-05 | Dsm Ip Assets Bv | Nuevos copolímeros de poliesteramida biodegradables para la administración de fármacos |
| US9102105B2 (en) * | 2011-09-13 | 2015-08-11 | Vista Scientific Llc | Method for forming an ocular drug delivery device |
| JP5989780B2 (ja) | 2011-09-14 | 2016-09-07 | フォーサイト・ビジョン５・インコーポレイテッドＦｏｒｓｉｇｈｔ Ｖｉｓｉｏｎ５，Ｉｎｃ． | 眼挿入装置および方法 |
| US20150038415A1 (en) * | 2011-12-16 | 2015-02-05 | Dsm Ip Assets B.V. | Process for the manufacturing of a drug delivery system based on a polymer comprising a dispersed bioactive agent |
| US8900300B1 (en) | 2012-02-22 | 2014-12-02 | Omega Ophthalmics Llc | Prosthetic capsular bag and method of inserting the same |
| CN104717962B (zh) | 2012-10-02 | 2017-07-21 | 帝斯曼知识产权资产管理有限公司 | 包含蛋白质和可生物降解聚酯酰胺的药物递送组合物 |
| RU2652063C2 (ru) | 2012-10-26 | 2018-04-24 | Форсайт Вижн5, Инк. | Офтальмологическая система для замедленного высвобождения лекарственного средства в глазу |
| WO2014179568A2 (en) | 2013-05-02 | 2014-11-06 | Odin Biotech | Two-layer ocular implant |
| AU2015266850B2 (en) | 2014-05-29 | 2019-12-05 | Glaukos Corporation | Implants with controlled drug delivery features and methods of using same |
| AU2015277207B2 (en) | 2014-06-19 | 2018-03-29 | Omega Ophthalmics Llc | Prosthetic capsular devices, systems, and methods |
| CN107645951B (zh) * | 2014-11-25 | 2021-05-04 | 艾克思摩尔有限公司 | 用于递送一种或多种生物活性剂的组合物和方法 |
| US10434071B2 (en) | 2014-12-18 | 2019-10-08 | Dsm Ip Assets, B.V. | Drug delivery system for delivery of acid sensitivity drugs |
| US9358103B1 (en) | 2015-02-10 | 2016-06-07 | Omega Ophthalmics Llc | Prosthetic capsular devices, systems, and methods |
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| WO2016187355A1 (en) * | 2015-05-20 | 2016-11-24 | Glaukos Corporation | Therapeutic drug compositions and implants for delivery of same |
| WO2017040853A1 (en) | 2015-09-02 | 2017-03-09 | Glaukos Corporation | Drug delivery implants with bi-directional delivery capacity |
| WO2017053885A1 (en) | 2015-09-25 | 2017-03-30 | Glaukos Corporation | Punctal implants with controlled drug delivery features and methods of using same |
| PT109154B (pt) * | 2016-02-12 | 2019-11-05 | Univ De Coimbra | Tecnologia não-invasiva de inserto ocular para libertação controlada de fármacos |
| AU2017252294B2 (en) | 2016-04-20 | 2021-12-02 | Glaukos Corporation | Bioresorbable ocular drug delivery device |
| US9993336B2 (en) | 2016-06-06 | 2018-06-12 | Omega Ophthalmics Llc | Prosthetic capsular devices, systems, and methods |
| WO2018075932A1 (en) | 2016-10-21 | 2018-04-26 | Omega Ophthalmics Llc | Prosthetic capsular devices, systems, and methods |
| US20200147055A1 (en) * | 2017-05-30 | 2020-05-14 | Eximore Ltd. | Compositions and methods for treating dry eye syndrome delivering antibiotic macrolide |
| AU2019249216B2 (en) | 2018-04-06 | 2024-07-18 | Omega Ophthalmics Llc | Prosthetic capsular devices, systems, and methods |
| KR20260007295A (ko) | 2018-05-24 | 2026-01-13 | 셀라니즈 이브이에이 퍼포먼스 폴리머스 엘엘씨 | 거대 분자 약물 화합물의 지속적인 방출을 위한 이식가능 장치 |
| EP3803866A4 (en) | 2018-05-24 | 2022-03-16 | Nureva Inc. | METHOD, APPARATUS, AND COMPUTER READABLE MATERIALS FOR MANAGING SEMI-CONSTANT (PERSISTENT) SOUND SOURCES IN MICROPHONE CATCH/HOME AREAS |
| MX2020012459A (es) | 2018-05-24 | 2021-04-28 | Celanese Eva Performance Polymers Llc | Dispositivo implantable para liberacion sostenida de un compuesto de farmaco macromolecular. |
| CN112566622A (zh) * | 2018-06-19 | 2021-03-26 | 细胞疗法有限责任公司 | 用于治疗青光眼或高眼压症的包含眼内压降低剂、cnp化合物、npr-b化合物、tie-2激动剂或神经营养剂的缓释药物递送系统 |
| AU2020302924A1 (en) | 2019-06-27 | 2022-02-17 | Layerbio, Inc. | Ocular device delivery methods and systems |
| CA3160955A1 (en) | 2019-11-12 | 2021-05-20 | Dsm Ip Assets B.V. | Polyesteramide copolymers possessing high glass transition temperatures |
| WO2022082170A1 (en) | 2020-10-12 | 2022-04-21 | Omega Ophthalmics Llc | Prosthetic capsular devices, systems, and methods |
| US12186512B2 (en) * | 2020-10-26 | 2025-01-07 | Christopher Green | Treatment for dry eyes |
| BR112023022439A2 (pt) | 2021-04-26 | 2023-12-26 | Celanese Eva Performance Polymers Llc | Dispositivo implantável para liberação sustentada de um composto de fármaco macromolecular |
| WO2024258996A1 (en) * | 2023-06-16 | 2024-12-19 | Baylor College Of Medicine | Ocular drug delivery |
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-
2011
- 2011-05-17 EP EP11784089.2A patent/EP2571526B1/en active Active
- 2011-05-17 CA CA2798084A patent/CA2798084A1/en not_active Abandoned
- 2011-05-17 WO PCT/US2011/036806 patent/WO2011146483A1/en not_active Ceased
- 2011-05-17 US US13/642,042 patent/US20130142858A1/en not_active Abandoned
- 2011-05-17 JP JP2013511293A patent/JP2013526572A/ja active Pending
- 2011-05-17 AU AU2011256259A patent/AU2011256259A1/en not_active Abandoned
-
2013
- 2013-07-22 US US13/947,564 patent/US8765166B2/en active Active
-
2015
- 2015-12-22 US US14/978,879 patent/US9808420B2/en active Active
-
2017
- 2017-10-18 US US15/787,600 patent/US10869833B2/en active Active
-
2020
- 2020-12-21 US US17/129,151 patent/US20210251892A1/en not_active Abandoned
-
2022
- 2022-08-12 US US17/887,261 patent/US20230094779A1/en not_active Abandoned
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