JP2013526485A5 - - Google Patents
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- JP2013526485A5 JP2013526485A5 JP2013509314A JP2013509314A JP2013526485A5 JP 2013526485 A5 JP2013526485 A5 JP 2013526485A5 JP 2013509314 A JP2013509314 A JP 2013509314A JP 2013509314 A JP2013509314 A JP 2013509314A JP 2013526485 A5 JP2013526485 A5 JP 2013526485A5
- Authority
- JP
- Japan
- Prior art keywords
- uveitis
- antibody
- pharmaceutical composition
- binding fragment
- retinal
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US33265810P | 2010-05-07 | 2010-05-07 | |
| US61/332,658 | 2010-05-07 | ||
| US33412510P | 2010-05-12 | 2010-05-12 | |
| US61/334,125 | 2010-05-12 | ||
| US201161444638P | 2011-02-18 | 2011-02-18 | |
| US61/444,638 | 2011-02-18 | ||
| PCT/US2011/035646 WO2011140522A1 (en) | 2010-05-07 | 2011-05-06 | METHODS FOR THE TREATMENT OF IL-1β RELATED CONDITIONS |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013526485A JP2013526485A (ja) | 2013-06-24 |
| JP2013526485A5 true JP2013526485A5 (enExample) | 2014-06-26 |
| JP5904645B2 JP5904645B2 (ja) | 2016-04-13 |
Family
ID=44904117
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013509314A Expired - Fee Related JP5904645B2 (ja) | 2010-05-07 | 2011-05-06 | ＩＬ−１β関連病態の治療のための方法 |
Country Status (15)
| Country | Link |
|---|---|
| US (2) | US8551487B2 (enExample) |
| EP (1) | EP2566520A4 (enExample) |
| JP (1) | JP5904645B2 (enExample) |
| KR (1) | KR20130065662A (enExample) |
| CN (1) | CN102883748A (enExample) |
| BR (1) | BR112012028557A2 (enExample) |
| CA (1) | CA2797846A1 (enExample) |
| EA (1) | EA201201526A1 (enExample) |
| IL (1) | IL222890A0 (enExample) |
| MX (1) | MX337586B (enExample) |
| NZ (1) | NZ603191A (enExample) |
| PH (1) | PH12012502143A1 (enExample) |
| SG (2) | SG2014014724A (enExample) |
| WO (1) | WO2011140522A1 (enExample) |
| ZA (1) | ZA201208172B (enExample) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JO3417B1 (ar) | 2010-01-08 | 2019-10-20 | Regeneron Pharma | الصيغ المستقرة التي تحتوي على الأجسام المضادة لمضاد مستقبل( interleukin-6 (il-6r |
| CN107320734A (zh) | 2011-04-29 | 2017-11-07 | 西莱克塔生物科技公司 | 从合成纳米载体中控制释放免疫抑制剂 |
| ES2895848T3 (es) * | 2012-12-17 | 2022-02-22 | Cell Medica Inc | Anticuerpos contra IL-1 beta |
| US10098535B2 (en) | 2013-03-13 | 2018-10-16 | Edwin Ryan | Dynamic optical coherence tomography device and method |
| CN105307641A (zh) | 2013-05-03 | 2016-02-03 | 西莱克塔生物科技公司 | 用于降低不期望体液免疫应答的给药组合 |
| EA201790551A1 (ru) | 2014-09-07 | 2017-07-31 | Селекта Байосайенсиз, Инк. | Способы и композиции для ослабления иммунных ответов к пропускающему экзон вирусному трансферному вектору |
| JP2017537896A (ja) | 2014-11-10 | 2017-12-21 | エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ | 二重特異性抗体及び眼科に使用する方法 |
| BR112018008900A8 (pt) | 2015-11-03 | 2019-02-26 | Regeneron Pharma | composições compreendendo anticorpos para il6r para o tratamento de uveíte e edema macular e métodos de uso das mesmas |
| EP3376939B1 (en) * | 2015-11-18 | 2022-05-11 | University Of Louisville Research Foundation, Inc. | Automated methods for the objective quantification of retinal characteristics by retinal region and diagnosis of retinal pathology |
| EP4599848A3 (en) | 2017-03-11 | 2025-12-03 | Cartesian Therapeutics, Inc. | Methods and compositions related to combined treatment with anti-inflammatories and synthetic nanocarriers comprising an immunosuppressant |
| EP3655961A4 (en) * | 2017-07-17 | 2021-09-01 | Massachusetts Institute of Technology | HEALTHY AND SICK BARRIER TISSUE CELL ATLAS |
| KR20260109977A (ko) | 2018-08-29 | 2026-07-13 | 리제너론 파아마슈티컬스, 인크. | 류마티스성 관절염을 갖는 대상체를 치료하기 위한 방법 및 조성물 |
| JP7542543B2 (ja) | 2019-01-31 | 2024-08-30 | サノフィ・バイオテクノロジー | 若年性特発性関節炎を治療するための抗ｉｌ－６受容体抗体 |
| JP2022545312A (ja) | 2019-04-24 | 2022-10-27 | サノフィ・バイオテクノロジー | 関節リウマチの診断及び処置の方法 |
| CA3142710A1 (en) | 2019-06-04 | 2020-12-10 | Sanofi Biotechnology | Compositions and methods for treating pain in subjects with rheumatoid arthritis |
| US12553041B2 (en) | 2019-06-04 | 2026-02-17 | Cartesian Therapeutics Inc. | Formulations and doses of pegylated uricase |
Family Cites Families (46)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0569687B1 (en) | 1984-05-18 | 2002-08-21 | New England Medical Center Hospitals, Inc. | Human IL-1 cDNA sequences encoding biologically-active human IL-1 proteins |
| DE3588241T2 (de) | 1984-05-18 | 2002-12-05 | Massachusetts Institute Of Technology, Cambridge | Menschliche IL-1 cDNS-Sequenzen die für biologisch aktive menschliche IL-1-Proteine kodieren |
| US4762914A (en) | 1984-05-18 | 1988-08-09 | Auron Philip E | Truncated protein of interleukin-1 |
| US5077219A (en) | 1984-05-18 | 1991-12-31 | New England Medical Center Hospitals | Human IL-1 cDNA sequences encoding biologically-active human IL-1 proteins |
| US5484887A (en) | 1984-06-19 | 1996-01-16 | Immunex Corporation | Homogeneous interleukin 1 |
| US5122459A (en) | 1984-12-31 | 1992-06-16 | Immunex Corporation | Gene encoding biologically active human interleukin 1 |
| US4772685A (en) | 1985-10-02 | 1988-09-20 | Merck & Co., Inc. | Immunogenic peptides of human interleukin-1 and the corresponding anti-peptide antibodies |
| US4935343A (en) | 1986-08-08 | 1990-06-19 | Syntex (U.S.A.) Inc. | Monoclonal antibodies for interleukin-1β |
| DK590387A (da) | 1986-11-13 | 1988-05-14 | Otsuka Pharma Co Ltd | Antistoffer mod interleukin-1 |
| US5474899A (en) | 1987-05-13 | 1995-12-12 | Cistron Biotechnology, Inc. | Selective immunoassay for IL-1 β |
| DE68925935T2 (de) | 1988-10-01 | 1996-08-14 | Otsuka Pharma Co Ltd | Antikörper gegen Interleukin-1-beta |
| ATE165114T1 (de) | 1989-02-27 | 1998-05-15 | New England Medical Center Inc | Il-1, dessen biologische aktivität inhibiert ist |
| IE922437A1 (en) | 1991-07-25 | 1993-01-27 | Idec Pharma Corp | Recombinant antibodies for human therapy |
| PT1024191E (pt) | 1991-12-02 | 2008-12-22 | Medical Res Council | Produção de auto-anticorpos a partir de reportórios de segmentos de anticorpo e exibidos em fagos |
| US5869619A (en) | 1991-12-13 | 1999-02-09 | Xoma Corporation | Modified antibody variable domains |
| WO1993011794A1 (en) | 1991-12-13 | 1993-06-24 | Xoma Corporation | Methods and materials for preparation of modified antibody variable domains and therapeutic uses thereof |
| WO1995001997A1 (en) | 1993-07-09 | 1995-01-19 | Smithkline Beecham Corporation | RECOMBINANT AND HUMANIZED IL-1β ANTIBODIES FOR TREATMENT OF IL-1 MEDIATED INFLAMMATORY DISORDERS IN MAN |
| US5959085A (en) | 1993-11-23 | 1999-09-28 | Schering Corporation | Human monoclonal antibodies against human cytokines and methods of making and using such antibodies |
| US5817476A (en) | 1995-06-07 | 1998-10-06 | Genetics Institute, Inc. | Polynucleotides encoding interleukin-1 receptor intracellular ligand proteins |
| GB0001448D0 (en) * | 2000-01-21 | 2000-03-08 | Novartis Ag | Organic compounds |
| EP1282435A2 (en) | 2000-05-12 | 2003-02-12 | Immunex Corporation | Interleukin-1 inhibitors in the treatment of diseases |
| GB0020685D0 (en) | 2000-08-22 | 2000-10-11 | Novartis Ag | Organic compounds |
| US20030026806A1 (en) | 2000-10-27 | 2003-02-06 | Amgen Inc. | Antibodies and other selective IL-1 binding agents that allow binding to IL-1 receptor but not activation thereof |
| US20030166069A1 (en) | 2000-11-28 | 2003-09-04 | Amgen, Inc. | Interleukin-1 receptor antagonist-like molecules and uses thereof |
| US6727234B2 (en) | 2001-04-03 | 2004-04-27 | University Of Iowa Research Foundation | Isoprenoid analog compounds and methods of making and use thereof |
| US20050075488A1 (en) | 2001-07-26 | 2005-04-07 | Bright Stuart Willis | Interleukin-1 beta antibodies |
| CA2842429A1 (en) | 2001-10-19 | 2003-05-01 | Genentech, Inc. | Compositions and methods for the diagnosis and treatment of inflammatory bowel disorders |
| AU2003208946A1 (en) | 2002-02-28 | 2003-09-16 | Eli Lilly And Company | Anti-interleukin-1 beta analogs |
| US7572770B2 (en) | 2002-06-27 | 2009-08-11 | University Of Zurich | Use of an interleukin 1 receptor antagonist and/or pyrrolidinedithiocarbamate for the treatment or prophylaxis of type 2 diabetes |
| MXPA05002514A (es) | 2002-09-06 | 2005-05-27 | Amgen Inc | Anticuerpo monoclonal anti-il-1r1 humano terapeutico. |
| JP4538461B2 (ja) | 2003-01-24 | 2010-09-08 | アプライド モレキュラー エボリューション，インコーポレイテッド | ヒトＩＬ−１βアンタゴニスト |
| GB0303337D0 (en) | 2003-02-13 | 2003-03-19 | Celltech R&D Ltd | Biological products |
| US20050159590A1 (en) | 2003-08-25 | 2005-07-21 | Galit Rotman | Variants of interleukin-1 receptor antagonist: compositions and uses thereof |
| SG146624A1 (en) | 2003-09-11 | 2008-10-30 | Kemia Inc | Cytokine inhibitors |
| US7732478B2 (en) | 2004-01-09 | 2010-06-08 | The Trustees Of Columbia University In The City Of New York | Methods for facilitating metabolic control |
| US20050152850A1 (en) | 2004-01-09 | 2005-07-14 | Engebretson Steven P. | Methods and compositions for facilitating metabolic control |
| WO2005084696A1 (en) | 2004-03-08 | 2005-09-15 | Universita'degli Studi Di Milano | Methods and agents for controlling intestinal inflammation and mucosal immunity using agents interacting with tir8/sigirr |
| US8618054B2 (en) | 2004-05-05 | 2013-12-31 | Valorisation-Rechereche Société en Commandite | Interleukin-1 receptor antagonists, compositions, and methods of treatment |
| US7121691B2 (en) * | 2004-09-22 | 2006-10-17 | Osram Sylvania Inc. | Lamp assembly with interchangeable light distributing cap |
| EP2361933A3 (en) * | 2005-01-26 | 2012-05-02 | Amgen Fremont Inc. | Antibodies against interleukin-1 beta |
| ES2335232T3 (es) | 2005-06-21 | 2010-03-23 | Xoma Technology Ltd. | Anticuerpos y fragmentos de los mismos que se unen a la il-1 beta. |
| EP1940880A2 (en) | 2005-10-14 | 2008-07-09 | Novo Nordisk A/S | Treating diabetes using inhibitors of il-1 |
| KR20110079922A (ko) * | 2006-04-14 | 2011-07-11 | 노파르티스 아게 | 안과 장애 치료를 위한 ｉｌ－1 항체의 용도 |
| WO2008077145A2 (en) | 2006-12-20 | 2008-06-26 | Xoma Technology Ltd. | Treatment of il-1-beta related diseases |
| WO2008082651A2 (en) | 2006-12-29 | 2008-07-10 | Abbott Laboratories | Dual-specific il-1a/ il-1b antibodies |
| EP2331564A4 (en) * | 2008-10-06 | 2013-02-20 | Carolus Therapeutics Inc | PROCESS FOR TREATMENT OF IGNITION |
-
2011
- 2011-05-06 BR BR112012028557A patent/BR112012028557A2/pt not_active IP Right Cessation
- 2011-05-06 EP EP20110778465 patent/EP2566520A4/en not_active Withdrawn
- 2011-05-06 EA EA201201526A patent/EA201201526A1/ru unknown
- 2011-05-06 US US13/102,768 patent/US8551487B2/en not_active Expired - Fee Related
- 2011-05-06 WO PCT/US2011/035646 patent/WO2011140522A1/en not_active Ceased
- 2011-05-06 KR KR20127031454A patent/KR20130065662A/ko not_active Withdrawn
- 2011-05-06 NZ NZ603191A patent/NZ603191A/en not_active IP Right Cessation
- 2011-05-06 SG SG2014014724A patent/SG2014014724A/en unknown
- 2011-05-06 JP JP2013509314A patent/JP5904645B2/ja not_active Expired - Fee Related
- 2011-05-06 CN CN201180022684XA patent/CN102883748A/zh active Pending
- 2011-05-06 CA CA 2797846 patent/CA2797846A1/en not_active Abandoned
- 2011-05-06 SG SG2012082301A patent/SG185473A1/en unknown
- 2011-05-06 PH PH1/2012/502143A patent/PH12012502143A1/en unknown
- 2011-05-06 MX MX2012012901A patent/MX337586B/es active IP Right Grant
-
2012
- 2012-10-30 ZA ZA2012/08172A patent/ZA201208172B/en unknown
- 2012-11-05 IL IL222890A patent/IL222890A0/en unknown
-
2013
- 2013-09-17 US US14/029,603 patent/US9139646B2/en active Active
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