JP2013523892A - 視覚障害を処置するための組成物および方法 - Google Patents

視覚障害を処置するための組成物および方法 Download PDF

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JP2013523892A
JP2013523892A JP2013505098A JP2013505098A JP2013523892A JP 2013523892 A JP2013523892 A JP 2013523892A JP 2013505098 A JP2013505098 A JP 2013505098A JP 2013505098 A JP2013505098 A JP 2013505098A JP 2013523892 A JP2013523892 A JP 2013523892A
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alkyl
retinal
substituted
oil
composition
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Japanese (ja)
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JP2013523892A5 (https=
Inventor
アーシュラ ヴイ ストーブリ
ヨン−シン リー
アラン シー フォスター
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Allergan Inc
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Allergan Inc
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/53Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/517Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • A61K31/4523Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/454Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/536Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines ortho- or peri-condensed with carbocyclic ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/5415Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with carbocyclic ring systems, e.g. phenothiazine, chlorpromazine, piroxicam
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0048Eye, e.g. artificial tears
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/06Antiglaucoma agents or miotics

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  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
JP2013505098A 2010-04-15 2011-04-13 視覚障害を処置するための組成物および方法 Pending JP2013523892A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US32463210P 2010-04-15 2010-04-15
US61/324,632 2010-04-15
PCT/US2011/032325 WO2011130411A1 (en) 2010-04-15 2011-04-13 Compositions and methods for treating visual disorders

Publications (2)

Publication Number Publication Date
JP2013523892A true JP2013523892A (ja) 2013-06-17
JP2013523892A5 JP2013523892A5 (https=) 2014-05-29

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ID=44009992

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JP2013505098A Pending JP2013523892A (ja) 2010-04-15 2011-04-13 視覚障害を処置するための組成物および方法

Country Status (8)

Country Link
US (1) US20110257186A1 (https=)
EP (1) EP2558100A1 (https=)
JP (1) JP2013523892A (https=)
KR (1) KR20130092976A (https=)
AU (1) AU2011239683A1 (https=)
CA (1) CA2796345A1 (https=)
RU (1) RU2012148214A (https=)
WO (1) WO2011130411A1 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2020503290A (ja) * 2016-12-15 2020-01-30 オフタラボ エス アール エル リサミングリーンの点眼液、及び眼科学におけるその使用

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109908327A (zh) * 2019-03-12 2019-06-21 广州陈锦济生物科技有限公司 一种用于治疗近视的眼药水及其制备方法

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2001512459A (ja) * 1997-02-13 2001-08-21 コーテックス ファーマシューティカルズ,インコーポレイテッド Ampaレセプタの活性を高めるベンゾフラザン化合物
JP2006516283A (ja) * 2003-01-13 2006-06-29 コーテックス ファーマシューティカルズ, インコーポレイテッド 睡眠不足とストレスに起因する知覚衰退の処置方法
US20080139472A1 (en) * 2006-10-06 2008-06-12 The Regents Of The University Of California Upregulating bdnf levels to mitigate mental retardation
WO2008085505A1 (en) * 2007-01-03 2008-07-17 Cortex Pharmaceuticals, Inc. 3-substituted-[1,2,3]benzotriazinone compounds for enhancing glutamatergic synaptic responses
WO2008085506A1 (en) * 2007-01-03 2008-07-17 Cortex Pharmaceuticals, Inc. 3-substituted-[1,2,3]-benzotriazinone compound for enhancing glutamatergic synaptic responses
WO2009038752A2 (en) * 2007-09-20 2009-03-26 Cortex Pharmaceuticals, Inc. 3-substituted 1,2,3-triazin-4-one's and 3-substituted 1,3-pyrimidinone's for enhancing glutamatergic synaptic responses
JP2009534415A (ja) * 2006-04-20 2009-09-24 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア ニューロトロフィン発現に対するampa受容体モジュレーターの作用の薬理学的制御

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2001512459A (ja) * 1997-02-13 2001-08-21 コーテックス ファーマシューティカルズ,インコーポレイテッド Ampaレセプタの活性を高めるベンゾフラザン化合物
JP2006516283A (ja) * 2003-01-13 2006-06-29 コーテックス ファーマシューティカルズ, インコーポレイテッド 睡眠不足とストレスに起因する知覚衰退の処置方法
JP2009534415A (ja) * 2006-04-20 2009-09-24 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア ニューロトロフィン発現に対するampa受容体モジュレーターの作用の薬理学的制御
US20080139472A1 (en) * 2006-10-06 2008-06-12 The Regents Of The University Of California Upregulating bdnf levels to mitigate mental retardation
WO2008085505A1 (en) * 2007-01-03 2008-07-17 Cortex Pharmaceuticals, Inc. 3-substituted-[1,2,3]benzotriazinone compounds for enhancing glutamatergic synaptic responses
WO2008085506A1 (en) * 2007-01-03 2008-07-17 Cortex Pharmaceuticals, Inc. 3-substituted-[1,2,3]-benzotriazinone compound for enhancing glutamatergic synaptic responses
WO2009038752A2 (en) * 2007-09-20 2009-03-26 Cortex Pharmaceuticals, Inc. 3-substituted 1,2,3-triazin-4-one's and 3-substituted 1,3-pyrimidinone's for enhancing glutamatergic synaptic responses

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
JPN6015010562; Brain Research, 1998, Vol.797, p.125-134 *
JPN6015010564; Journal of Neurophysiology, 1997, Vol.77, p.57-64 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2020503290A (ja) * 2016-12-15 2020-01-30 オフタラボ エス アール エル リサミングリーンの点眼液、及び眼科学におけるその使用
JP7296316B2 (ja) 2016-12-15 2023-06-22 オフタラボ エス アール エル リサミングリーンの点眼液、及び眼科学におけるその使用

Also Published As

Publication number Publication date
US20110257186A1 (en) 2011-10-20
WO2011130411A1 (en) 2011-10-20
KR20130092976A (ko) 2013-08-21
CA2796345A1 (en) 2011-10-20
RU2012148214A (ru) 2014-05-20
AU2011239683A1 (en) 2012-11-08
EP2558100A1 (en) 2013-02-20

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