JP2013521763A5 - - Google Patents
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- Publication number
- JP2013521763A5 JP2013521763A5 JP2012553011A JP2012553011A JP2013521763A5 JP 2013521763 A5 JP2013521763 A5 JP 2013521763A5 JP 2012553011 A JP2012553011 A JP 2012553011A JP 2012553011 A JP2012553011 A JP 2012553011A JP 2013521763 A5 JP2013521763 A5 JP 2013521763A5
- Authority
- JP
- Japan
- Prior art keywords
- rrna
- biomarkers
- campylobacter
- subject
- ccni
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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- 108020004465 16S ribosomal RNA Proteins 0.000 claims 47
- 239000000090 biomarker Substances 0.000 claims 21
- 238000000034 method Methods 0.000 claims 13
- 239000000523 sample Substances 0.000 claims 9
- 241000589996 Campylobacter rectus Species 0.000 claims 8
- 241000589992 Campylobacter showae Species 0.000 claims 8
- 102100036873 Cyclin-I Human genes 0.000 claims 8
- 102100021066 Fibroblast growth factor receptor substrate 2 Human genes 0.000 claims 8
- 102000016251 GREB1 Human genes 0.000 claims 8
- 108050004787 GREB1 Proteins 0.000 claims 8
- 101000713124 Homo sapiens Cyclin-I Proteins 0.000 claims 8
- 101000818410 Homo sapiens Fibroblast growth factor receptor substrate 2 Proteins 0.000 claims 8
- 241000134844 Porphyromonas catoniae Species 0.000 claims 8
- 210000003296 saliva Anatomy 0.000 claims 8
- 102100037665 Fibroblast growth factor 9 Human genes 0.000 claims 7
- 101001027380 Homo sapiens Fibroblast growth factor 9 Proteins 0.000 claims 7
- 101000984753 Homo sapiens Serine/threonine-protein kinase B-raf Proteins 0.000 claims 7
- -1 LZTS Proteins 0.000 claims 7
- 102100027103 Serine/threonine-protein kinase B-raf Human genes 0.000 claims 7
- 241000194017 Streptococcus Species 0.000 claims 7
- 102000052116 epidermal growth factor receptor activity proteins Human genes 0.000 claims 7
- 108700015053 epidermal growth factor receptor activity proteins Proteins 0.000 claims 7
- YOHYSYJDKVYCJI-UHFFFAOYSA-N n-[3-[[6-[3-(trifluoromethyl)anilino]pyrimidin-4-yl]amino]phenyl]cyclopropanecarboxamide Chemical compound FC(F)(F)C1=CC=CC(NC=2N=CN=C(NC=3C=C(NC(=O)C4CC4)C=CC=3)C=2)=C1 YOHYSYJDKVYCJI-UHFFFAOYSA-N 0.000 claims 7
- 241000201858 Granulicatella adiacens Species 0.000 claims 6
- 102000014702 Haptoglobin Human genes 0.000 claims 6
- 108050005077 Haptoglobin Proteins 0.000 claims 6
- 239000007787 solid Substances 0.000 claims 6
- 102100040006 Annexin A1 Human genes 0.000 claims 5
- 101000959738 Homo sapiens Annexin A1 Proteins 0.000 claims 5
- 102000001109 Leukocyte L1 Antigen Complex Human genes 0.000 claims 5
- 108010069316 Leukocyte L1 Antigen Complex Proteins 0.000 claims 5
- 241001148135 Veillonella parvula Species 0.000 claims 5
- 102100021144 Zinc-alpha-2-glycoprotein Human genes 0.000 claims 5
- 101710201241 Zinc-alpha-2-glycoprotein Proteins 0.000 claims 5
- 238000003556 assay Methods 0.000 claims 5
- 206010058467 Lung neoplasm malignant Diseases 0.000 claims 4
- 201000005202 lung cancer Diseases 0.000 claims 4
- 208000020816 lung neoplasm Diseases 0.000 claims 4
- 238000012163 sequencing technique Methods 0.000 claims 3
- 241000605894 Porphyromonas Species 0.000 claims 2
- 229940096118 ella Drugs 0.000 claims 2
- 239000003446 ligand Substances 0.000 claims 2
- 238000004949 mass spectrometry Methods 0.000 claims 2
- 108020004707 nucleic acids Proteins 0.000 claims 2
- 102000039446 nucleic acids Human genes 0.000 claims 2
- 150000007523 nucleic acids Chemical class 0.000 claims 2
- 229920001184 polypeptide Polymers 0.000 claims 2
- 102000004196 processed proteins & peptides Human genes 0.000 claims 2
- 108090000765 processed proteins & peptides Proteins 0.000 claims 2
- OOLLAFOLCSJHRE-ZHAKMVSLSA-N ulipristal acetate Chemical compound C1=CC(N(C)C)=CC=C1[C@@H]1C2=C3CCC(=O)C=C3CC[C@H]2[C@H](CC[C@]2(OC(C)=O)C(C)=O)[C@]2(C)C1 OOLLAFOLCSJHRE-ZHAKMVSLSA-N 0.000 claims 2
- 102000004145 Annexin A1 Human genes 0.000 claims 1
- 108090000663 Annexin A1 Proteins 0.000 claims 1
- 238000002965 ELISA Methods 0.000 claims 1
- 241000235796 Granulicatella Species 0.000 claims 1
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 claims 1
- 239000000427 antigen Substances 0.000 claims 1
- 108091007433 antigens Proteins 0.000 claims 1
- 102000036639 antigens Human genes 0.000 claims 1
- 238000000684 flow cytometry Methods 0.000 claims 1
- 238000009396 hybridization Methods 0.000 claims 1
- 238000010166 immunofluorescence Methods 0.000 claims 1
- 238000003364 immunohistochemistry Methods 0.000 claims 1
- 238000002493 microarray Methods 0.000 claims 1
- 102000004169 proteins and genes Human genes 0.000 claims 1
- 108090000623 proteins and genes Proteins 0.000 claims 1
- 239000007790 solid phase Substances 0.000 claims 1
- 238000011895 specific detection Methods 0.000 claims 1
- 210000002784 stomach Anatomy 0.000 claims 1
- 238000001262 western blot Methods 0.000 claims 1
- 239000011701 zinc Substances 0.000 claims 1
- 229910052725 zinc Inorganic materials 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US30320510P | 2010-02-10 | 2010-02-10 | |
| US61/303,205 | 2010-02-10 | ||
| PCT/US2011/024415 WO2011100483A1 (en) | 2010-02-10 | 2011-02-10 | Salivary biomarkers for lung cancer detection |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013521763A JP2013521763A (ja) | 2013-06-13 |
| JP2013521763A5 true JP2013521763A5 (https=) | 2014-03-13 |
| JP6114035B2 JP6114035B2 (ja) | 2017-04-12 |
Family
ID=44368127
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012553011A Active JP6114035B2 (ja) | 2010-02-10 | 2011-02-10 | 肺癌検出用唾液バイオマーカー |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US9689039B2 (https=) |
| EP (1) | EP2534265A4 (https=) |
| JP (1) | JP6114035B2 (https=) |
| KR (1) | KR101824746B1 (https=) |
| CN (1) | CN102906275A (https=) |
| AU (1) | AU2011215789A1 (https=) |
| CA (1) | CA2789494C (https=) |
| WO (1) | WO2011100483A1 (https=) |
Families Citing this family (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104198709A (zh) * | 2008-09-09 | 2014-12-10 | 私募蛋白质体公司 | 肺癌生物标记及其用途 |
| CN103415624B (zh) | 2010-08-13 | 2017-03-01 | 私募蛋白质体公司 | 胰腺癌生物标记及其用途 |
| ES2402457B2 (es) * | 2011-10-19 | 2014-01-20 | Universidade De Vigo | Procedimiento para el diagnóstico de derrame pleural maligno mediante la determinación de la concentración de calprotectina en líquido pleural. |
| US20150008314A1 (en) * | 2012-01-26 | 2015-01-08 | The Cleveland Clinic Foundation | Diagnostic and prognostic biomarkers for cancer |
| EP3578984A3 (en) | 2013-10-28 | 2020-03-04 | Salivatech Co., Ltd. | Salivary biomarkers for oral cancer |
| WO2015148909A1 (en) * | 2014-03-28 | 2015-10-01 | Mayo Foundation For Medical Education And Research | Methods and materials for treating endometrial cancer |
| EP3152560B1 (en) * | 2014-06-03 | 2022-08-24 | The Regents of The University of California | Non-invasive gene mutation detection in lung cancer patients |
| GB2552271B (en) * | 2014-12-19 | 2020-10-21 | Aberystwyth Univ | A method for diagnosing lung cancer |
| CN104894269B (zh) * | 2015-06-09 | 2016-03-02 | 广东省人民医院 | 基于MassARRAY质谱平台Iplex分析的肺癌基因谱检测试剂盒 |
| EP3403093A4 (en) * | 2016-01-12 | 2019-08-07 | Arizona Board of Regents on behalf of Arizona State University | PLASMA-AUTOANTIKÖRPER BIOMARKERS FOR THE DIAGNOSIS OF LUNG CANCER |
| WO2017210662A1 (en) * | 2016-06-03 | 2017-12-07 | Castle Biosciences, Inc. | Methods for predicting risk of recurrence and/or metastasis in soft tissue sarcoma |
| CN106526187B (zh) * | 2016-09-13 | 2018-04-13 | 浙江理工大学 | 一种基于Annexin A1蛋白的白血病检测试剂盒 |
| CN116908452A (zh) | 2016-12-16 | 2023-10-20 | 布里格姆及妇女医院股份有限公司 | 用于疾病的早期检测的蛋白质冠传感器阵列的系统和方法 |
| US20210072255A1 (en) | 2016-12-16 | 2021-03-11 | The Brigham And Women's Hospital, Inc. | System and method for protein corona sensor array for early detection of diseases |
| KR101833348B1 (ko) * | 2016-12-26 | 2018-03-02 | 주식회사 엠디헬스케어 | 세균 메타게놈 분석을 통한 유방암 진단방법 |
| KR101833503B1 (ko) * | 2016-12-26 | 2018-03-05 | 주식회사 엠디헬스케어 | 만성폐쇄성폐질환자에서 세균 메타게놈 분석을 통한 폐암 진단방법 |
| KR101940426B1 (ko) * | 2016-12-28 | 2019-01-18 | 주식회사 엠디헬스케어 | 세균 메타게놈 분석을 통한 대장종양 진단 방법 |
| CN107202773B (zh) * | 2017-06-01 | 2019-07-05 | 重庆大学 | 一种利用聚苯乙烯球的细胞周期散射光强模型建立方法 |
| IL272810B2 (en) * | 2017-08-21 | 2025-10-01 | Savicell Diagnostic Ltd | Methods for diagnosing and treating lung cancer |
| CN108070656B (zh) * | 2017-11-13 | 2021-11-09 | 深圳华大因源医药科技有限公司 | 肺癌标志物及其应用 |
| CN108333375B (zh) * | 2018-04-20 | 2020-08-11 | 山东省千佛山医院 | 肺非小细胞癌早期特异性自身抗体panel诊断试剂盒 |
| JP7066540B2 (ja) * | 2018-06-14 | 2022-05-13 | 株式会社日立製作所 | デジタルｐｃｒの測定方法および測定装置 |
| CN108676888B (zh) * | 2018-07-12 | 2022-01-28 | 吉林大学 | 一种肺部恶性肿瘤易感性预测试剂盒及系统 |
| CN119264211A (zh) | 2018-08-27 | 2025-01-07 | 瑞泽恩制药公司 | 拉曼光谱在下游纯化中的应用 |
| KR20260016611A (ko) | 2018-11-07 | 2026-02-03 | 시어 인코퍼레이티드 | 단백질 코로나 분석을 위한 조성물, 방법 및 시스템 및 그것들의 용도 |
| WO2020128546A1 (en) * | 2018-12-20 | 2020-06-25 | Kromat Műszerforgalmazó Kft. | A simple, non-invasive method for diagnosing oral cancer |
| EP3671213A1 (en) * | 2018-12-20 | 2020-06-24 | Kromat Muszerforgalmazó Kft. | In vitro method for the diagnosis of malignant conditions |
| JP7518852B2 (ja) | 2019-03-26 | 2024-07-18 | シアー， インコーポレイテッド | 生物流体からのタンパク質コロナ分析のための組成物、方法およびシステム、ならびにそれらの使用 |
| CN117169534A (zh) | 2019-08-05 | 2023-12-05 | 禧尔公司 | 用于样品制备、数据生成和蛋白质冠分析的系统和方法 |
| KR102473361B1 (ko) * | 2020-02-24 | 2022-12-01 | 한림대학교 산학협력단 | 기계식 인공호흡 환자의 미생물 프로파일링으로 탈관 성공률과 28일 생존율을 예측하는 방법 |
| CN111735869A (zh) * | 2020-05-29 | 2020-10-02 | 中山大学 | 一种蛋白质的检测试剂及检测方法 |
| IL300826A (en) | 2020-08-25 | 2023-04-01 | Seer Inc | Compositions and methods for testing proteins and nucleic acids |
| KR102732170B1 (ko) * | 2021-05-20 | 2024-11-19 | 한국식품연구원 | 구강미생물 정보를 이용한 폐암의 조기진단 및 위험성 예측 방법 또는 이를 위한 조성물 |
| WO2022261781A1 (en) * | 2021-06-18 | 2022-12-22 | Ember Katie | Methods and systems for interrogating a drop of saliva using raman spectroscopy |
| CN119979743A (zh) * | 2025-04-11 | 2025-05-13 | 华中科技大学同济医学院附属协和医院 | 用于预测良恶性肺结节的呼出气冷凝液微生物组合、试剂盒及应用 |
| CN120490462A (zh) * | 2025-07-16 | 2025-08-15 | 成都中医药大学 | 一种用于肺结节的微生物筛查试剂盒及筛查方法 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20030094281A (ko) * | 2001-03-12 | 2003-12-11 | 모노젠, 인크. | 세포에 기초한 질병상태의 검출 및 질병상태의 구별 |
| WO2004046386A1 (en) * | 2002-11-15 | 2004-06-03 | Genomic Health, Inc. | Gene expression profiling of egfr positive cancer |
| US20090204334A1 (en) * | 2004-03-30 | 2009-08-13 | Eastern Virginia Medical School | Lung cancer biomarkers |
| JP2008536480A (ja) * | 2005-02-17 | 2008-09-11 | ダナ−ファーバー キャンサー インスティテュート，インコーポレイテッド | 癌の同定、評価、予防、および治療用組成物、キット、および方法、ならびに癌の治療法 |
| WO2006105642A1 (en) * | 2005-04-05 | 2006-10-12 | British Columbia Cancer Agency | Biomarkers for the detection of lung cancer and uses thereof |
| US20080286273A1 (en) * | 2007-05-02 | 2008-11-20 | Siemens Medical Solutions Usa, Inc. | Knowledge-Based Proliferation Signatures and Methods of Use |
| EP2201363A4 (en) * | 2007-09-18 | 2011-03-16 | Univ Texas | DETECTION OF SPOKEN PROTEINS WITH SECONDARY MODULATION TO DUCTAL CARCINOMA IN SITU OF CHEST |
| GB0803192D0 (en) | 2008-02-22 | 2008-04-02 | Mubio Products Bv | SCLC biomarker panel |
| WO2009154790A2 (en) * | 2008-06-20 | 2009-12-23 | University Of Massachusetts | Novel metastasis suppresor genes and uses thereof |
| US20110123441A1 (en) * | 2009-10-23 | 2011-05-26 | University Of Miami | Novel greb1a monoclonal antibody |
-
2011
- 2011-02-10 US US13/025,130 patent/US9689039B2/en not_active Expired - Fee Related
- 2011-02-10 JP JP2012553011A patent/JP6114035B2/ja active Active
- 2011-02-10 WO PCT/US2011/024415 patent/WO2011100483A1/en not_active Ceased
- 2011-02-10 KR KR1020127023529A patent/KR101824746B1/ko not_active Expired - Fee Related
- 2011-02-10 EP EP11742826.8A patent/EP2534265A4/en not_active Withdrawn
- 2011-02-10 CA CA2789494A patent/CA2789494C/en active Active
- 2011-02-10 AU AU2011215789A patent/AU2011215789A1/en not_active Abandoned
- 2011-02-10 CN CN2011800181891A patent/CN102906275A/zh active Pending
-
2017
- 2017-04-25 US US15/496,277 patent/US20170306414A1/en not_active Abandoned
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