JP2013518057A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2013518057A5 JP2013518057A5 JP2012550189A JP2012550189A JP2013518057A5 JP 2013518057 A5 JP2013518057 A5 JP 2013518057A5 JP 2012550189 A JP2012550189 A JP 2012550189A JP 2012550189 A JP2012550189 A JP 2012550189A JP 2013518057 A5 JP2013518057 A5 JP 2013518057A5
- Authority
- JP
- Japan
- Prior art keywords
- lys
- dmt
- arg
- phe
- trp
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 108090000765 processed proteins & peptides Proteins 0.000 claims 5
- 230000002438 mitochondrial effect Effects 0.000 claims 4
- 230000037050 permeability transition Effects 0.000 claims 4
- 241000124008 Mammalia Species 0.000 claims 2
- 239000003814 drug Substances 0.000 claims 2
- 238000004519 manufacturing process Methods 0.000 claims 2
- 230000004792 oxidative damage Effects 0.000 claims 2
- 239000008194 pharmaceutical composition Substances 0.000 claims 2
- 102000004196 processed proteins & peptides Human genes 0.000 claims 2
- 239000003937 drug carrier Substances 0.000 claims 1
- 150000003839 salts Chemical class 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US29806210P | 2010-01-25 | 2010-01-25 | |
| US61/298,062 | 2010-01-25 | ||
| PCT/US2011/022247 WO2011091357A1 (en) | 2010-01-25 | 2011-01-24 | Aromatic-cationic peptides and uses of same |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015163826A Division JP2016000750A (ja) | 2010-01-25 | 2015-08-21 | 芳香族カチオン性ペプチドおよびその使用 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2013518057A JP2013518057A (ja) | 2013-05-20 |
| JP2013518057A5 true JP2013518057A5 (OSRAM) | 2014-03-13 |
Family
ID=44307257
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012550189A Pending JP2013518057A (ja) | 2010-01-25 | 2011-01-24 | 芳香族カチオン性ペプチドおよびその使用 |
| JP2015163826A Pending JP2016000750A (ja) | 2010-01-25 | 2015-08-21 | 芳香族カチオン性ペプチドおよびその使用 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015163826A Pending JP2016000750A (ja) | 2010-01-25 | 2015-08-21 | 芳香族カチオン性ペプチドおよびその使用 |
Country Status (8)
| Country | Link |
|---|---|
| US (6) | US20120329730A1 (OSRAM) |
| EP (4) | EP2848628A1 (OSRAM) |
| JP (2) | JP2013518057A (OSRAM) |
| CN (2) | CN104725472A (OSRAM) |
| AU (2) | AU2011207432A1 (OSRAM) |
| CA (2) | CA3008993A1 (OSRAM) |
| HK (1) | HK1208686A1 (OSRAM) |
| WO (1) | WO2011091357A1 (OSRAM) |
Families Citing this family (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2011025734A1 (en) | 2009-08-24 | 2011-03-03 | Stealth Peptides International, Inc. | Methods and compositions for preventing or treating ophthalmic conditions |
| CN104922653A (zh) * | 2010-02-26 | 2015-09-23 | 佛罗里达大学研究基金会有限公司 | 治疗或预防哺乳动物对象中骨骼肌衰弱的方法 |
| EP3040080A1 (en) | 2010-03-15 | 2016-07-06 | Stealth Peptides International, Inc. | Combination therapies using cyclosporine and aromatic cationic peptides |
| EP2566880A4 (en) * | 2010-05-03 | 2014-10-08 | Stealth Peptides Int Inc | AROMATIC-CATIONIC PEPTIDES AND USES THEREOF |
| CN102327600A (zh) * | 2011-09-14 | 2012-01-25 | 中国人民解放军军事医学科学院放射与辐射医学研究所 | 用于预防和治疗辐射损伤的rx31肽 |
| CN103987397A (zh) | 2011-09-29 | 2014-08-13 | 梅约医学教育与研究基金会 | 芳族阳离子肽和使用它们的方法 |
| EP2788013A4 (en) * | 2011-12-09 | 2015-08-19 | Stealth Peptides Int Inc | AROMATIC-CATIONIC PEPTIDES AND USES THEREOF |
| US9636378B2 (en) * | 2012-03-30 | 2017-05-02 | Stealth Biotherapeutics Corp | Methods and compositions for the prevention and treatment neuropathy |
| CA2870200A1 (en) * | 2012-04-12 | 2013-10-17 | Stealth Peptides International, Inc. | Aromatic-cationic peptides and uses of same |
| EP4091624A1 (en) | 2013-03-15 | 2022-11-23 | Protagonist Therapeutics, Inc. | Hepcidin analogues and uses thereof |
| US20140294902A1 (en) * | 2013-04-02 | 2014-10-02 | Protagonist Therapeutics, Inc. | Novel a4b7 peptide antagonists |
| CA2916492A1 (en) * | 2013-06-27 | 2014-12-31 | Stealth Biotherapeutics Corp | Peptide therapeutics and methods for using same |
| US20160175379A1 (en) * | 2013-08-12 | 2016-06-23 | Stealth Bio Therapeutics Corp | Combination therapy for the treatment of ischemia-reperfusion injury |
| WO2015084875A1 (en) * | 2013-12-02 | 2015-06-11 | Stealth Peptides International, Inc. | Compositions and methods for treating vitiligo |
| CA2949215C (en) | 2014-05-16 | 2023-03-14 | Protagonist Therapeutics, Inc. | .alpha.4.beta.7 integrin thioether peptide antagonists |
| EP4378536A3 (en) | 2014-07-17 | 2024-10-09 | Protagonist Therapeutics, Inc. | Oral peptide inhibitors of interleukin-23 receptor and their use to treat inflammatory bowel diseases |
| SG11201702553RA (en) | 2014-10-01 | 2017-04-27 | Protagonist Therapeutics Inc | NOVEL α4β7 PEPTIDE MONOMER AND DIMER ANTAGONISTS |
| JP6854771B2 (ja) | 2015-03-06 | 2021-04-07 | ステルス バイオセラピューティックス コープ | 薬学的に適切なペプチドを調製するための方法 |
| US10787490B2 (en) | 2015-07-15 | 2020-09-29 | Protaganist Therapeutics, Inc. | Peptide inhibitors of interleukin-23 receptor and their use to treat inflammatory diseases |
| JP6533723B2 (ja) * | 2015-09-11 | 2019-06-19 | キユーピー株式会社 | 抗酸化剤 |
| CA3006698A1 (en) * | 2015-11-30 | 2017-06-08 | Peter Schiller | Aromatic-cationic peptides conjugated to antioxidants and their use in treating complex regional pain syndrome |
| WO2017117411A1 (en) | 2015-12-30 | 2017-07-06 | Protagonist Therapeutics, Inc. | Analogues of hepcidin mimetics with improved in vivo half lives |
| US11548913B2 (en) | 2015-12-31 | 2023-01-10 | Stealth Biotherapeutics Inc. | Therapeutic compositions including peptides and uses thereof |
| EP3426675B1 (en) | 2016-03-11 | 2020-08-05 | Stealth BioTherapeutics Inc. | Crystalline salt forms |
| CA3020393A1 (en) | 2016-04-11 | 2017-10-19 | Carnot, Llc | Chiral peptides |
| EP3606938A1 (en) | 2017-04-05 | 2020-02-12 | Stealth BioTherapeutics Corp | Crystalline salt forms of boc-d-arg-dmt-lys-(boc)-phe-nh2 |
| EP4092038A1 (en) * | 2017-09-11 | 2022-11-23 | Protagonist Therapeutics, Inc. | Opioid agonist peptides and uses thereof |
| CA3089868A1 (en) | 2018-02-08 | 2019-08-15 | Protagonist Therapeutics, Inc. | Conjugated hepcidin mimetics |
| KR20210093958A (ko) * | 2018-12-18 | 2021-07-28 | 스텔스 바이오테라퓨틱스 코포레이션 | 미토콘드리아 질환을 표적으로 하는 유사체 |
| KR20220044277A (ko) | 2019-07-10 | 2022-04-07 | 프로타고니스트 테라퓨틱스, 인코포레이티드 | 인터루킨-23 수용체의 펩티드 억제제 및 염증성 질환을 치료하기 위한 이의 용도 |
| WO2021146454A1 (en) | 2020-01-15 | 2021-07-22 | Janssen Biotech, Inc. | Peptide inhibitors of interleukin-23 receptor and their use to treat inflammatory diseases |
| WO2021146441A1 (en) | 2020-01-15 | 2021-07-22 | Janssen Biotech, Inc. | Peptide inhibitors of interleukin-23 receptor and their use to treat inflammatory diseases |
| EP4247403A4 (en) | 2020-11-20 | 2024-12-11 | JANSSEN Pharmaceutica NV | COMPOSITIONS OF PEPTIDE INHIBITORS OF THE INTERLEUKIN-23 RECEPTOR |
| CN117881411A (zh) | 2021-06-01 | 2024-04-12 | 艾迪雅生物有限责任公司 | 用于眼部药物的延长释放药物递送系统和使用方法 |
| JP2024525732A (ja) | 2021-07-14 | 2024-07-12 | ヤンセン バイオテツク，インコーポレーテツド | インターロイキン－２３受容体の脂質化ペプチド阻害剤 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4522811A (en) | 1982-07-08 | 1985-06-11 | Syntex (U.S.A.) Inc. | Serial injection of muramyldipeptides and liposomes enhances the anti-infective activity of muramyldipeptides |
| EP0273696A2 (en) * | 1987-01-02 | 1988-07-06 | Merck & Co. Inc. | Renin inhibitors containing histidine replacements |
| WO1991006563A1 (en) * | 1989-11-06 | 1991-05-16 | Farmitalia Carlo Erba S.R.L. | Reduced irreversible bombesin antagonists |
| EP0592512A1 (en) * | 1991-07-01 | 1994-04-20 | University Technologies International Inc. (Uti) | NON-DESENSITIZING ANALOGS OF GnRH AND OTHER BIOLOGICALLY ACTIVE LIGANDS |
| US5858784A (en) | 1991-12-17 | 1999-01-12 | The Regents Of The University Of California | Expression of cloned genes in the lung by aerosol- and liposome-based delivery |
| US5674534A (en) | 1992-06-11 | 1997-10-07 | Alkermes, Inc. | Composition for sustained release of non-aggregated erythropoietin |
| US5716644A (en) | 1992-06-11 | 1998-02-10 | Alkermes, Inc. | Composition for sustained release of non-aggregated erythropoietin |
| US5989463A (en) | 1997-09-24 | 1999-11-23 | Alkermes Controlled Therapeutics, Inc. | Methods for fabricating polymer-based controlled release devices |
| US6245740B1 (en) | 1998-12-23 | 2001-06-12 | Amgen Inc. | Polyol:oil suspensions for the sustained release of proteins |
| ES2436011T3 (es) * | 2003-02-04 | 2013-12-26 | Cornell Research Foundation, Inc. | Métodos para prevenir la transición de la permeabilidad mitocondrial |
| CA2851972C (en) * | 2004-01-23 | 2015-06-23 | Cornell Research Foundation, Inc. | Methods for reducing oxidative damage |
| EP2252312B1 (en) * | 2008-02-07 | 2014-04-09 | Cornell University | Methods for preventing or treating insulin resistance |
| US8143219B2 (en) * | 2008-02-26 | 2012-03-27 | Cornell University | Methods for prevention and treatment of acute renal injury |
-
2011
- 2011-01-24 CA CA3008993A patent/CA3008993A1/en not_active Abandoned
- 2011-01-24 EP EP14194189.8A patent/EP2848628A1/en not_active Withdrawn
- 2011-01-24 CA CA2787331A patent/CA2787331A1/en not_active Abandoned
- 2011-01-24 EP EP15185546.7A patent/EP3018138A1/en not_active Withdrawn
- 2011-01-24 WO PCT/US2011/022247 patent/WO2011091357A1/en not_active Ceased
- 2011-01-24 AU AU2011207432A patent/AU2011207432A1/en not_active Abandoned
- 2011-01-24 CN CN201510081030.4A patent/CN104725472A/zh active Pending
- 2011-01-24 EP EP14155476.6A patent/EP2733150A1/en not_active Withdrawn
- 2011-01-24 US US13/519,083 patent/US20120329730A1/en not_active Abandoned
- 2011-01-24 JP JP2012550189A patent/JP2013518057A/ja active Pending
- 2011-01-24 CN CN2011800071355A patent/CN102834408A/zh active Pending
- 2011-01-24 EP EP11735303.7A patent/EP2528934A4/en not_active Withdrawn
-
2013
- 2013-08-07 US US13/961,313 patent/US20130316964A1/en not_active Abandoned
-
2014
- 2014-09-16 US US14/488,007 patent/US20150005242A1/en not_active Abandoned
-
2015
- 2015-08-21 JP JP2015163826A patent/JP2016000750A/ja active Pending
- 2015-09-23 HK HK15109345.6A patent/HK1208686A1/xx unknown
-
2016
- 2016-02-05 AU AU2016200747A patent/AU2016200747A1/en not_active Abandoned
- 2016-02-11 US US15/041,235 patent/US20170008925A1/en not_active Abandoned
-
2017
- 2017-10-11 US US15/729,838 patent/US20180244721A1/en not_active Abandoned
-
2018
- 2018-11-30 US US16/206,777 patent/US20190330272A1/en not_active Abandoned
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2013518057A5 (OSRAM) | ||
| JP2011513241A5 (OSRAM) | ||
| JP2011511805A5 (OSRAM) | ||
| JP2012126742A5 (OSRAM) | ||
| EP2326718A4 (en) | INHBB EPITOP PEPTIDES AND VACCINES CONTAINING THEM | |
| HK1215934A1 (zh) | 肽治疗剂及其使用方法 | |
| JP2010534684A5 (OSRAM) | ||
| CL2013003331A1 (es) | Tableta de liberacion inmediata a prueba de alteracion que comprende (i) una matriz, y (ii) una pluralidad de material particulado, que comprende un opiaceo y un polimero de oxido de polietileno de mas de 20.000 g/mol, donde el multiparticulado forma una fase discontinua dentro de la matriz. | |
| WO2011156453A3 (en) | Therapeutic peptides | |
| AR086998A1 (es) | Coagonistas del receptor de glucagon/glp-1 | |
| IL212184A (en) | Conditional expression vector of protein (s) acting as immunomodulator (s), engineered training cells, their pharmaceutical composition and their use in drug preparation | |
| WO2016004093A3 (en) | Therapeutic compositions including galectin-3 inhibitors and uses thereof | |
| JP2013523703A5 (OSRAM) | ||
| WO2011094357A8 (en) | Respiratory virus epitopes templated into double stranded coiled -coils and use thereof in immunization | |
| JP2007262090A5 (OSRAM) | ||
| JP2011136997A5 (OSRAM) | ||
| JP2015510393A5 (OSRAM) | ||
| WO2009117041A3 (en) | Use of pyrene to carry peptides across the blood brain barrier | |
| JP2014532722A5 (OSRAM) | ||
| JP2012521201A5 (OSRAM) | ||
| JP2013510169A5 (OSRAM) | ||
| JP2012529293A5 (OSRAM) | ||
| WO2008069917A3 (en) | Novel cyclic peptides | |
| WO2015183995A3 (en) | Therapeutic compositions including frataxin, lactoferrin, and mitochondrial energy generating enzymes, and uses thereof | |
| JP2014050390A5 (OSRAM) |