JP2013517776A - タンパク質の生成を改善するための方法および組成物 - Google Patents

タンパク質の生成を改善するための方法および組成物 Download PDF

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Publication number
JP2013517776A
JP2013517776A JP2012550188A JP2012550188A JP2013517776A JP 2013517776 A JP2013517776 A JP 2013517776A JP 2012550188 A JP2012550188 A JP 2012550188A JP 2012550188 A JP2012550188 A JP 2012550188A JP 2013517776 A JP2013517776 A JP 2013517776A
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Prior art keywords
albumin
cells
supplement
cell
recombinant
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Pending
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JP2012550188A
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English (en)
Japanese (ja)
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JP2013517776A5 (enExample
Inventor
バーネット，マイケル
クローガン，マシュー，エス．
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Invitria Inc
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Ventria Bioscience Inc
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Publication of JP2013517776A publication Critical patent/JP2013517776A/ja
Publication of JP2013517776A5 publication Critical patent/JP2013517776A5/ja
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0018—Culture media for cell or tissue culture
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/76—Albumins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/76—Albumins
    • C07K14/765—Serum albumin, e.g. HSA
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8257—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/70—Undefined extracts
    • C12N2500/76—Undefined extracts from plants
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/70—Undefined extracts
    • C12N2500/80—Undefined extracts from animals
    • C12N2500/84—Undefined extracts from animals from mammals
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/90—Serum-free medium, which may still contain naturally-sourced components
    • C12N2500/92—Medium free of human- or animal-derived components
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/998—Proteins not provided for elsewhere

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
JP2012550188A 2010-01-25 2011-01-24 タンパク質の生成を改善するための方法および組成物 Pending JP2013517776A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US29810010P 2010-01-25 2010-01-25
US61/298,100 2010-01-25
PCT/US2011/022229 WO2011091350A2 (en) 2010-01-25 2011-01-24 Methods & compositions for improving protein production

Publications (2)

Publication Number Publication Date
JP2013517776A true JP2013517776A (ja) 2013-05-20
JP2013517776A5 JP2013517776A5 (enExample) 2013-08-15

Family

ID=44307638

Family Applications (1)

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JP2012550188A Pending JP2013517776A (ja) 2010-01-25 2011-01-24 タンパク質の生成を改善するための方法および組成物

Country Status (9)

Country Link
US (1) US20130157356A1 (enExample)
EP (1) EP2529006A4 (enExample)
JP (1) JP2013517776A (enExample)
KR (1) KR20130056853A (enExample)
CN (1) CN102812121A (enExample)
AU (1) AU2011207425A1 (enExample)
CA (1) CA2787942A1 (enExample)
SG (1) SG182618A1 (enExample)
WO (1) WO2011091350A2 (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2019533442A (ja) * 2016-10-04 2019-11-21 アルブミディクス リミティド 組換え酵母由来血清アルブミンの使用
JP2023022317A (ja) * 2013-12-20 2023-02-14 バイオジェン・エムエイ・インコーポレイテッド 生物薬剤フェドバッチ生産能力及び生産物品質を改善するための灌流シード培養の使用

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KR20120018827A (ko) 2009-02-20 2012-03-05 벤트리아 바이오사이언스 단백질의 조합을 함유하는 세포 배양 배지
WO2011075686A2 (en) * 2009-12-18 2011-06-23 Ventria Bioscience Methods & compositions comprising heat shock proteins
JP2013060416A (ja) * 2011-08-23 2013-04-04 Niigata Univ イネ由来成分を含有する感染防御用組成物
US10104881B2 (en) 2012-09-27 2018-10-23 Cefo Co., Ltd. Composition comprising plant-derived recombinant human serum albumin, lipids, and plant protein hydrolysates as active ingredients for cryopreservation of stem cells or primary cells
WO2014145091A1 (en) * 2013-03-15 2014-09-18 Genentech, Inc. Cell culture media and methods of antibody production
JP6206792B2 (ja) * 2013-04-03 2017-10-04 誠一 横尾 培地及び細胞の培養方法
AU2015211258A1 (en) * 2014-01-31 2016-08-11 Trustees Of Boston University Offline glucose control based on preceding periods
CN105037560B (zh) * 2015-08-06 2019-02-05 中国农业科学院生物技术研究所 培育表达shTRAIL植物的方法
SG11201908891YA (en) * 2017-03-31 2019-10-30 Boehringer Ingelheim Int Perfusion medium
CN111285932B (zh) * 2018-12-10 2023-07-11 武汉禾元生物科技股份有限公司 一种从基因工程水稻种子中分离纯化重组人纤维连接蛋白的方法
CN109867715B (zh) * 2019-02-28 2022-06-17 中国科学院昆明植物研究所 一种叶绿体蛋白和ATPase酶活性突变体在提高植物抗逆性中的应用
US10894812B1 (en) 2020-09-30 2021-01-19 Alpine Roads, Inc. Recombinant milk proteins
EP4222167A1 (en) 2020-09-30 2023-08-09 Nobell Foods, Inc. Recombinant milk proteins and food compositions comprising the same
US10947552B1 (en) 2020-09-30 2021-03-16 Alpine Roads, Inc. Recombinant fusion proteins for producing milk proteins in plants
CN112516357B (zh) * 2020-11-26 2021-12-10 江苏中慧元通生物科技有限公司 一种疫苗生产用消毒柜
CN113917140B (zh) * 2021-10-28 2023-08-18 生工生物工程（上海）股份有限公司 一种快速筛选原核蛋白表达菌的方法
CN115786362B (zh) * 2022-09-05 2024-02-13 四川农业大学 一种控制稻米品质的热激蛋白家族基因hsp110-3及其应用
CN118063586B (zh) * 2024-04-03 2025-06-24 独步吾奇生物医疗科技(江苏)有限公司 一种人碱性成纤维细胞生长因子的制备方法

Citations (7)

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Publication number Priority date Publication date Assignee Title
JP2006342169A (ja) * 1995-05-25 2006-12-21 Delta Biotechnology Ltd 高純度アルブミンの製造
WO2007002762A2 (en) * 2005-06-28 2007-01-04 Ventria Bioscience Components of cell culture media produced from plant cells
JP2007509609A (ja) * 2003-10-02 2007-04-19 ザ、リージェンツ、オブ、ザ、ユニバーシティ、オブ、ミシガン 幹細胞拘束および骨形成を誘導するヒト前立腺癌細胞因子
JP2007231225A (ja) * 2006-03-03 2007-09-13 Jellice Co Ltd エンドトキシン含有量を低減したゼラチンの製造方法および低エンドトキシンゼラチン
WO2007137149A2 (en) * 2006-05-22 2007-11-29 Velcura Therapeutics, Inc. Use of cathepsin k antagonists in bone production
WO2009011139A1 (ja) * 2007-07-13 2009-01-22 Mitsubishi Tanabe Pharma Corporation 細胞の単離方法、細胞用無血清培養培地および細胞の培養方法
JP2012518409A (ja) * 2009-02-20 2012-08-16 ベントリア・バイオサイエンス タンパク質の組み合わせを含有する細胞培養培地

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US6210683B1 (en) * 1997-09-05 2001-04-03 Merck & Co., Inc. Stabilizers containing recombinant human serum albumin for live virus vaccines
US6762053B2 (en) * 2000-06-09 2004-07-13 Vitrolife, Inc. Mammalian gamete and embryo culture media and culture media supplements
WO2006047380A2 (en) * 2004-10-22 2006-05-04 Amgen, Inc. Method and media for single cell serum-fee culture of cho cells
US7989205B2 (en) * 2005-10-06 2011-08-02 American Cryostem Corporation Cell culture media, kits and methods of use

Patent Citations (7)

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JP2006342169A (ja) * 1995-05-25 2006-12-21 Delta Biotechnology Ltd 高純度アルブミンの製造
JP2007509609A (ja) * 2003-10-02 2007-04-19 ザ、リージェンツ、オブ、ザ、ユニバーシティ、オブ、ミシガン 幹細胞拘束および骨形成を誘導するヒト前立腺癌細胞因子
WO2007002762A2 (en) * 2005-06-28 2007-01-04 Ventria Bioscience Components of cell culture media produced from plant cells
JP2007231225A (ja) * 2006-03-03 2007-09-13 Jellice Co Ltd エンドトキシン含有量を低減したゼラチンの製造方法および低エンドトキシンゼラチン
WO2007137149A2 (en) * 2006-05-22 2007-11-29 Velcura Therapeutics, Inc. Use of cathepsin k antagonists in bone production
WO2009011139A1 (ja) * 2007-07-13 2009-01-22 Mitsubishi Tanabe Pharma Corporation 細胞の単離方法、細胞用無血清培養培地および細胞の培養方法
JP2012518409A (ja) * 2009-02-20 2012-08-16 ベントリア・バイオサイエンス タンパク質の組み合わせを含有する細胞培養培地

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2023022317A (ja) * 2013-12-20 2023-02-14 バイオジェン・エムエイ・インコーポレイテッド 生物薬剤フェドバッチ生産能力及び生産物品質を改善するための灌流シード培養の使用
JP2019533442A (ja) * 2016-10-04 2019-11-21 アルブミディクス リミティド 組換え酵母由来血清アルブミンの使用
JP2021176336A (ja) * 2016-10-04 2021-11-11 アルブミディクス リミティド 組換え酵母由来血清アルブミンの使用
JP7249387B2 (ja) 2016-10-04 2023-03-30 アルブミディクス リミティド 組換え酵母由来血清アルブミンの使用

Also Published As

Publication number Publication date
CN102812121A (zh) 2012-12-05
AU2011207425A2 (en) 2012-08-30
WO2011091350A9 (en) 2012-02-16
KR20130056853A (ko) 2013-05-30
EP2529006A4 (en) 2014-01-08
WO2011091350A3 (en) 2011-12-29
EP2529006A2 (en) 2012-12-05
AU2011207425A1 (en) 2012-08-16
CA2787942A1 (en) 2011-07-28
US20130157356A1 (en) 2013-06-20
SG182618A1 (en) 2012-08-30
WO2011091350A2 (en) 2011-07-28

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