JP2013517279A - 化合物及び方法 - Google Patents

化合物及び方法 Download PDF

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Publication number
JP2013517279A
JP2013517279A JP2012549065A JP2012549065A JP2013517279A JP 2013517279 A JP2013517279 A JP 2013517279A JP 2012549065 A JP2012549065 A JP 2012549065A JP 2012549065 A JP2012549065 A JP 2012549065A JP 2013517279 A JP2013517279 A JP 2013517279A
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alkyl
optionally substituted
compound
cycloalkyl
substituted
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JP2013517279A5 (enExample
Inventor
エルカン、バログル
ショミール、ゴーシュ
メルセデス、ロベラ
ダービー、シュミット
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Tempero Pharmaceuticals Inc
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Tempero Pharmaceuticals Inc
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    • C—CHEMISTRY; METALLURGY
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    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
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    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Diabetes (AREA)
  • Immunology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Communicable Diseases (AREA)
  • Hematology (AREA)
  • Neurology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Virology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pulmonology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Obesity (AREA)
  • Dermatology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Psychiatry (AREA)
  • AIDS & HIV (AREA)
  • Child & Adolescent Psychology (AREA)
  • Transplantation (AREA)
JP2012549065A 2010-01-13 2011-01-13 化合物及び方法 Pending JP2013517279A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US29464310P 2010-01-13 2010-01-13
US61/294,643 2010-01-13
PCT/US2011/021099 WO2011088187A1 (en) 2010-01-13 2011-01-13 Compounds and methods

Publications (2)

Publication Number Publication Date
JP2013517279A true JP2013517279A (ja) 2013-05-16
JP2013517279A5 JP2013517279A5 (enExample) 2014-02-27

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JP2012549065A Pending JP2013517279A (ja) 2010-01-13 2011-01-13 化合物及び方法

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US (1) US20120322827A1 (enExample)
EP (1) EP2523560A4 (enExample)
JP (1) JP2013517279A (enExample)
WO (1) WO2011088187A1 (enExample)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101781663B1 (ko) 2010-01-13 2017-09-25 템페로 파마슈티칼즈, 인크. 히스톤 데아세틸라제 효소를 억제하기 위한 화합물 및 이를 제조하는 방법
EP2523664A4 (en) 2010-01-13 2013-06-26 Tempero Pharmaceuticals Inc COMPOUNDS AND METHODS
EA201490228A1 (ru) 2011-07-08 2014-08-29 Новартис Аг Новые производные трифторметилоксадиазола и их применение для лечения заболевания
WO2013009810A1 (en) * 2011-07-13 2013-01-17 Tempero Pharmaceuticals, Inc. Methods of treatment
WO2013009812A1 (en) * 2011-07-13 2013-01-17 Tempero Pharmaceuticals, Inc Methods of treatment
WO2013009827A1 (en) * 2011-07-13 2013-01-17 Tempero Pharmaceuticals, Inc. Methods of treatment
WO2013009830A1 (en) * 2011-07-13 2013-01-17 Tempero Pharmaceuticals, Inc. Methods of treatment
WO2013066834A1 (en) * 2011-10-31 2013-05-10 Glaxosmithkline Llc Compounds and methods
WO2013066836A1 (en) * 2011-10-31 2013-05-10 Glaxosmithkline Llc Compounds and methods
WO2013066832A1 (en) * 2011-10-31 2013-05-10 Glaxosmithkline Llc Compounds and methods
US10357493B2 (en) 2017-03-10 2019-07-23 Selenity Therapeutics (Bermuda), Ltd. Metalloenzyme inhibitor compounds
CN114727974A (zh) 2019-07-30 2022-07-08 艾科尼佐治疗股份有限公司 Hdac6抑制剂及其用途
WO2022169985A1 (en) 2021-02-03 2022-08-11 Eikonizo Therapeutics, Inc. Hdac6 inhibitors and uses thereof
AU2023250964A1 (en) 2022-04-08 2024-11-07 Eikonizo Therapeutics, Inc. Oxadiazole hdac6 inhibitors and uses thereof

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JPN6014052025; Ｊｏｎｅｓ　Ｐ　ｅｔ　ａｌ: Ｂｉｏｏｒｇ　Ｍｅｄ　Ｃｈｅｍ　Ｌｅｔｔ Ｖｏｌ．１８, 2008, ｐ．３４５６-６１ *
JPN6014052027; Ｓｃａｒｐｅｌｌｉ　Ｒ　ｅｔ　ａｌ: Ｂｉｏｏｒｇ　Ｍｅｄ　Ｃｈｅｍ　Ｌｅｔｔ Ｖｏｌ．１８, 2008, ｐ．６０７８-８２ *
JPN6014052028; Ｍｕｒａｇｌｉａ　Ｅ　ｅｔ　ａｌ: Ｂｉｏｏｒｇ　Ｍｅｄ　Ｃｈｅｍ　Ｌｅｔｔ Ｖｏｌ．１８, 2008, ｐ．６０８３-７ *

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