JP2013516454A5 - - Google Patents

Download PDF

Info

Publication number
JP2013516454A5
JP2013516454A5 JP2012547585A JP2012547585A JP2013516454A5 JP 2013516454 A5 JP2013516454 A5 JP 2013516454A5 JP 2012547585 A JP2012547585 A JP 2012547585A JP 2012547585 A JP2012547585 A JP 2012547585A JP 2013516454 A5 JP2013516454 A5 JP 2013516454A5
Authority
JP
Japan
Prior art keywords
pharmaceutical composition
seq
administration
adenoviral vector
sequence shown
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2012547585A
Other languages
English (en)
Japanese (ja)
Other versions
JP2013516454A (ja
JP6196040B2 (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/IL2011/000007 external-priority patent/WO2011083464A2/en
Publication of JP2013516454A publication Critical patent/JP2013516454A/ja
Publication of JP2013516454A5 publication Critical patent/JP2013516454A5/ja
Application granted granted Critical
Publication of JP6196040B2 publication Critical patent/JP6196040B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2012547585A 2010-01-05 2011-01-05 特異的な抗血管形成アデノウイルス剤の使用法 Expired - Fee Related JP6196040B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US28222810P 2010-01-05 2010-01-05
US61/282,228 2010-01-05
US28224710P 2010-01-07 2010-01-07
US61/282,247 2010-01-07
PCT/IL2011/000007 WO2011083464A2 (en) 2010-01-05 2011-01-05 Methods for use of a specific anti-angiogenic adenoviral agent

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2017085788A Division JP2017186341A (ja) 2010-01-05 2017-04-25 特異的な抗血管形成アデノウイルス剤の使用法

Publications (3)

Publication Number Publication Date
JP2013516454A JP2013516454A (ja) 2013-05-13
JP2013516454A5 true JP2013516454A5 (enExample) 2014-02-20
JP6196040B2 JP6196040B2 (ja) 2017-09-13

Family

ID=44305892

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2012547585A Expired - Fee Related JP6196040B2 (ja) 2010-01-05 2011-01-05 特異的な抗血管形成アデノウイルス剤の使用法
JP2017085788A Pending JP2017186341A (ja) 2010-01-05 2017-04-25 特異的な抗血管形成アデノウイルス剤の使用法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2017085788A Pending JP2017186341A (ja) 2010-01-05 2017-04-25 特異的な抗血管形成アデノウイルス剤の使用法

Country Status (11)

Country Link
US (3) US9567605B2 (enExample)
EP (2) EP3159405B8 (enExample)
JP (2) JP6196040B2 (enExample)
KR (1) KR101754437B1 (enExample)
AU (1) AU2011204405B2 (enExample)
CA (1) CA2786374C (enExample)
DK (2) DK3159405T3 (enExample)
MX (1) MX342641B (enExample)
NZ (1) NZ601324A (enExample)
SG (2) SG182367A1 (enExample)
WO (1) WO2011083464A2 (enExample)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2003222427B8 (en) 2000-11-17 2010-04-29 Vascular Biogenics Ltd. Promoters exhibiting endothelial cell specificity and methods of using same
US8071740B2 (en) * 2000-11-17 2011-12-06 Vascular Biogenics Ltd. Promoters exhibiting endothelial cell specificity and methods of using same for regulation of angiogenesis
US6838452B2 (en) 2000-11-24 2005-01-04 Vascular Biogenics Ltd. Methods employing and compositions containing defined oxidized phospholipids for prevention and treatment of atherosclerosis
KR100866117B1 (ko) 2001-10-19 2008-10-31 바스큘라 바이오제닉스 리미티드 혈관형성의 표적화 억제조절 및 항암 치료를 위한폴리뉴클레오타이드 작제물, 약학적 조성물 및 방법
CA2658972C (en) 2006-07-31 2019-11-26 Vascular Biogenics Ltd. Polypeptides and polynucleotides encoding same and use thereof in the treatment of medical conditions associated with ischemia
EP2521777B1 (en) 2010-01-05 2016-12-28 Vascular Biogenics Ltd. Compositions and methods for treating glioblastoma gbm
NZ601324A (en) 2010-01-05 2014-10-31 Vascular Biogenics Ltd Methods for use of a specific anti-angiogenic adenoviral agent
KR102229084B1 (ko) 2012-10-17 2021-03-18 바스큘라 바이오제닉스 리미티드 아데노바이러스를 사용하는 치료 방법
US9511046B2 (en) * 2013-01-11 2016-12-06 Abraxis Bioscience, Llc Methods of treating pancreatic cancer
WO2014118643A2 (en) 2013-02-04 2014-08-07 Vascular Biogenics Ltd. Methods of inducing responsiveness to anti-angiogenic agent
US9771385B2 (en) 2014-11-26 2017-09-26 Vascular Biogenics Ltd. Oxidized lipids
CN106999506A (zh) 2014-11-26 2017-08-01 脉管生物生长有限公司 氧化脂质以及纤维化的治疗或预防
CN111356480A (zh) 2017-10-20 2020-06-30 脉管生物生长有限公司 用于抗血管生成剂疗法的诊断方法
US10525127B2 (en) * 2018-03-31 2020-01-07 Femtomab P14.7 protein and uses thereof as vaccine adjuvant
CA3103367A1 (en) * 2018-06-13 2019-12-19 The Council Of The Queensland Institute Of Medical Research Viral detection assay
US20220154212A1 (en) * 2019-03-13 2022-05-19 Vascular Biogenics Ltd. Methods of anti-tumor therapy
BR112021020225A2 (pt) 2019-04-12 2021-12-07 Vascular Biogenics Ltd Métodos de terapia antitumoral

Family Cites Families (48)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL154600B (nl) 1971-02-10 1977-09-15 Organon Nv Werkwijze voor het aantonen en bepalen van specifiek bindende eiwitten en hun corresponderende bindbare stoffen.
NL154598B (nl) 1970-11-10 1977-09-15 Organon Nv Werkwijze voor het aantonen en bepalen van laagmoleculire verbindingen en van eiwitten die deze verbindingen specifiek kunnen binden, alsmede testverpakking.
NL154599B (nl) 1970-12-28 1977-09-15 Organon Nv Werkwijze voor het aantonen en bepalen van specifiek bindende eiwitten en hun corresponderende bindbare stoffen, alsmede testverpakking.
US3901654A (en) 1971-06-21 1975-08-26 Biological Developments Receptor assays of biologically active compounds employing biologically specific receptors
US3853987A (en) 1971-09-01 1974-12-10 W Dreyer Immunological reagent and radioimmuno assay
US3867517A (en) 1971-12-21 1975-02-18 Abbott Lab Direct radioimmunoassay for antigens and their antibodies
NL171930C (nl) 1972-05-11 1983-06-01 Akzo Nv Werkwijze voor het aantonen en bepalen van haptenen, alsmede testverpakkingen.
US3850578A (en) 1973-03-12 1974-11-26 H Mcconnell Process for assaying for biologically active molecules
US3935074A (en) 1973-12-17 1976-01-27 Syva Company Antibody steric hindrance immunoassay with two antibodies
US3996345A (en) 1974-08-12 1976-12-07 Syva Company Fluorescence quenching with immunological pairs in immunoassays
US4034074A (en) 1974-09-19 1977-07-05 The Board Of Trustees Of Leland Stanford Junior University Universal reagent 2-site immunoradiometric assay using labelled anti (IgG)
US3984533A (en) 1975-11-13 1976-10-05 General Electric Company Electrophoretic method of detecting antigen-antibody reaction
US4098876A (en) 1976-10-26 1978-07-04 Corning Glass Works Reverse sandwich immunoassay
US4879219A (en) 1980-09-19 1989-11-07 General Hospital Corporation Immunoassay utilizing monoclonal high affinity IgM antibodies
US5011771A (en) 1984-04-12 1991-04-30 The General Hospital Corporation Multiepitopic immunometric assay
US4666828A (en) 1984-08-15 1987-05-19 The General Hospital Corporation Test for Huntington's disease
US4683202A (en) 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
US4801531A (en) 1985-04-17 1989-01-31 Biotechnology Research Partners, Ltd. Apo AI/CIII genomic polymorphisms predictive of atherosclerosis
US5272057A (en) 1988-10-14 1993-12-21 Georgetown University Method of detecting a predisposition to cancer by the use of restriction fragment length polymorphism of the gene for human poly (ADP-ribose) polymerase
US5192659A (en) 1989-08-25 1993-03-09 Genetype Ag Intron sequence analysis method for detection of adjacent and remote locus alleles as haplotypes
US5281521A (en) 1992-07-20 1994-01-25 The Trustees Of The University Of Pennsylvania Modified avidin-biotin technique
US5747340A (en) 1994-06-03 1998-05-05 Syntex (U.S.A.) Inc. Targeted gene expression using preproendothelin-1 promoters
US7732129B1 (en) 1998-12-01 2010-06-08 Crucell Holland B.V. Method for the production and purification of adenoviral vectors
JP4492826B2 (ja) 1996-11-20 2010-06-30 イントロジェン セラピューティクス,インコーポレイテッド アデノウイルスベクターの産生および精製のための改良された方法
US6204055B1 (en) 1999-04-12 2001-03-20 Isis Pharmaceuticals, Inc. Antisense inhibition of Fas mediated signaling
US7691370B2 (en) 1998-10-15 2010-04-06 Canji, Inc. Selectivity replicating viral vector
US6649158B1 (en) 1998-10-15 2003-11-18 Canji, Inc. Methods and compositions to induce antitumor response
EP1185627A2 (en) 1999-06-01 2002-03-13 Cornell Research Foundation, Inc. Activation of dendritic cells to enhance immunity
IL130608A0 (en) 1999-06-23 2000-06-01 Compugen Ltd Novel nucleic and amino acid sequence
US6867022B1 (en) * 2000-01-21 2005-03-15 Regents Of The University Of Michigan Replication deficient adenovirus vectors and methods of making and using them
US8039261B2 (en) 2000-11-17 2011-10-18 Vascular Biogenics Ltd. Promoters exhibiting endothelial cell specificity and methods of using same for regulation of angiogenesis
CA2429342C (en) 2000-11-17 2013-03-19 Vascular Biogenics Ltd. Promoters exhibiting endothelial cell specificity and methods of using same
US20070286845A1 (en) * 2000-11-17 2007-12-13 Vascular Biogenics Ltd. Promoters exhibiting endothelial cell specificity and methods of using same for regulation of angiogenesis
US20100282634A1 (en) 2000-11-17 2010-11-11 Dror Harats Promoters Exhibiting Endothelial Cell Specificity and Methods of Using Same for Regulation of Angiogenesis
US8071740B2 (en) 2000-11-17 2011-12-06 Vascular Biogenics Ltd. Promoters exhibiting endothelial cell specificity and methods of using same for regulation of angiogenesis
AU2003222427B8 (en) 2000-11-17 2010-04-29 Vascular Biogenics Ltd. Promoters exhibiting endothelial cell specificity and methods of using same
US7067649B2 (en) 2000-11-17 2006-06-27 Vascular Biogenics Ltd. Promoters exhibiting endothelial cell specificity and methods of using same
KR100866117B1 (ko) 2001-10-19 2008-10-31 바스큘라 바이오제닉스 리미티드 혈관형성의 표적화 억제조절 및 항암 치료를 위한폴리뉴클레오타이드 작제물, 약학적 조성물 및 방법
CA2511665A1 (en) * 2002-12-18 2004-07-01 Novartis Ag Endothelial cell specifically binding peptides
US20080293652A1 (en) 2004-02-24 2008-11-27 Introgen Therapeutics, Inc. Combination of Ad-P53 and Chemotherapy for the Treatment of Tumours
EP1786904A4 (en) 2004-08-09 2010-06-16 Merck Sharp & Dohme Adenovirus vector COMPOSITIONS
WO2006079176A1 (en) 2005-01-28 2006-08-03 Apollo Life Sciences Limited Molecules and chimeric molecules thereof
CN101360499B (zh) * 2005-10-06 2015-10-07 默沙东公司 吡唑并[1,5-a]嘧啶衍生物在制备抑制蛋白激酶的药物中的用途
CA2658972C (en) 2006-07-31 2019-11-26 Vascular Biogenics Ltd. Polypeptides and polynucleotides encoding same and use thereof in the treatment of medical conditions associated with ischemia
NZ601324A (en) 2010-01-05 2014-10-31 Vascular Biogenics Ltd Methods for use of a specific anti-angiogenic adenoviral agent
EP2521777B1 (en) 2010-01-05 2016-12-28 Vascular Biogenics Ltd. Compositions and methods for treating glioblastoma gbm
JP6009357B2 (ja) 2010-01-12 2016-10-19 バスキュラー バイオジェニックス リミテッド アデノウイルスベクターの生産方法およびそれによって生成されるウイルス調製物
KR102229084B1 (ko) 2012-10-17 2021-03-18 바스큘라 바이오제닉스 리미티드 아데노바이러스를 사용하는 치료 방법

Similar Documents

Publication Publication Date Title
JP2013516454A5 (enExample)
Di et al. Combined adjuvant of poly I: C improves antitumor effects of CAR-T cells
Bartee et al. Tumor-localized secretion of soluble PD1 enhances oncolytic virotherapy
Fang et al. Emerging nano-/biotechnology drives oncolytic virus-activated and combined cancer immunotherapy
Longo et al. Immunotherapeutic approaches for hepatocellular carcinoma
JP2021063120A5 (enExample)
JP7146739B2 (ja) 癌を処置するためのアデノウイルスとチェックポイント阻害剤の組合せ
US12576131B2 (en) Altering inflammatory states of immune cells in vivo by modulating cellular activation states
JP2008507536A5 (enExample)
JP2016538885A5 (enExample)
JP2013189456A5 (enExample)
JP2016533753A5 (enExample)
JP2019506862A5 (enExample)
Castillo-Rodriguez et al. Suicide HSVtk gene delivery by neurotensin-polyplex nanoparticles via the bloodstream and GCV Treatment specifically inhibit the growth of human MDA-MB-231 triple negative breast cancer tumors xenografted in athymic mice
WO2014198852A2 (en) A dosing regime and formulations for type b adenoviruses
Thoidingjam et al. Oncolytic virus-based suicide gene therapy for cancer treatment: A perspective of the clinical trials conducted at Henry Ford Health
Zhu et al. Recent advances in oncolytic virus therapy for hepatocellular carcinoma
Gonzalez-Aseguinolaza et al. Gene therapy of liver diseases: a 2011 perspective
JP2011503039A5 (enExample)
Zhou et al. An update on the clinical trial research of immunotherapy for glioblastoma
Hu et al. Nanomaterial manipulation of immune microenvironment in the diseased liver
Parrasia et al. Targeting pancreatic ductal adenocarcinoma (PDAC)
Snyder et al. Good CARMA: Turning bad tumor‐resident myeloid cells good with chimeric antigen receptor macrophages
Warricker et al. The role of NK cells in oncolytic viral therapy: a focus on hepatocellular carcinoma
TW202309077A (zh) 用於治療實性瘤的靶向cd70的基因工程化免疫細胞