JP2013516188A5 - - Google Patents

Info

Publication number

JP2013516188A5

JP2013516188A5 JP2012548051A JP2012548051A JP2013516188A5 JP 2013516188 A5 JP2013516188 A5 JP 2013516188A5 JP 2012548051 A JP2012548051 A JP 2012548051A JP 2012548051 A JP2012548051 A JP 2012548051A JP 2013516188 A5 JP2013516188 A5 JP 2013516188A5

Authority

JP

Japan

Prior art keywords

diet

animal

dietary supplement

dietary

amount

Prior art date

2011-01-05

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Granted

Links

• Espacenet
• Global Dossier
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• 235000005911 diet Nutrition 0.000 claims 43
• 230000037213 diet Effects 0.000 claims 37
• 241001465754 Metazoa Species 0.000 claims 26
• 235000015872 dietary supplement Nutrition 0.000 claims 20
• 235000020934 caloric restriction Nutrition 0.000 claims 12
• 238000002560 therapeutic procedure Methods 0.000 claims 12
• PHIQHXFUZVPYII-ZCFIWIBFSA-N (R)-carnitine Chemical compound C[N+](C)(C)C[C@H](O)CC([O-])=O PHIQHXFUZVPYII-ZCFIWIBFSA-N 0.000 claims 8
• GVJHHUAWPYXKBD-UHFFFAOYSA-N (±)-α-Tocopherol Chemical compound OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 claims 8
• CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 claims 8
• 235000011201 Ginkgo Nutrition 0.000 claims 6
• 241000218628 Ginkgo Species 0.000 claims 6
• 235000008100 Ginkgo biloba Nutrition 0.000 claims 6
• 230000000378 dietary effect Effects 0.000 claims 6
• 230000003278 mimic effect Effects 0.000 claims 5
• ZZZCUOFIHGPKAK-UHFFFAOYSA-N D-erythro-ascorbic acid Natural products OCC1OC(=O)C(O)=C1O ZZZCUOFIHGPKAK-UHFFFAOYSA-N 0.000 claims 4
• 229930003268 Vitamin C Natural products 0.000 claims 4
• 229930003427 Vitamin E Natural products 0.000 claims 4
• XUJNEKJLAYXESH-UHFFFAOYSA-N cysteine Natural products SCC(N)C(O)=O XUJNEKJLAYXESH-UHFFFAOYSA-N 0.000 claims 4
• 235000018417 cysteine Nutrition 0.000 claims 4
• 239000000284 extract Substances 0.000 claims 4
• WIGCFUFOHFEKBI-UHFFFAOYSA-N gamma-tocopherol Natural products CC(C)CCCC(C)CCCC(C)CCCC1CCC2C(C)C(O)C(C)C(C)C2O1 WIGCFUFOHFEKBI-UHFFFAOYSA-N 0.000 claims 4
• 235000019154 vitamin C Nutrition 0.000 claims 4
• 239000011718 vitamin C Substances 0.000 claims 4
• 235000019165 vitamin E Nutrition 0.000 claims 4
• 229940046009 vitamin E Drugs 0.000 claims 4
• 239000011709 vitamin E Substances 0.000 claims 4
• 239000009140 Grape Seed Proanthocyanidin Substances 0.000 claims 3
• 239000003795 chemical substances by application Substances 0.000 claims 3
• 102000003728 Peroxisome Proliferator-Activated Receptors Human genes 0.000 claims 2
• 108090000029 Peroxisome Proliferator-Activated Receptors Proteins 0.000 claims 2
• 235000013305 food Nutrition 0.000 claims 2
• JPFCOVZKLAXXOE-XBNSMERZSA-N (3r)-2-(3,5-dihydroxy-4-methoxyphenyl)-8-[(2r,3r,4r)-3,5,7-trihydroxy-2-(4-hydroxyphenyl)-3,4-dihydro-2h-chromen-4-yl]-3,4-dihydro-2h-chromene-3,5,7-triol Chemical compound C1=C(O)C(OC)=C(O)C=C1C1[C@H](O)CC(C(O)=CC(O)=C2[C@H]3C4=C(O)C=C(O)C=C4O[C@@H]([C@@H]3O)C=3C=CC(O)=CC=3)=C2O1 JPFCOVZKLAXXOE-XBNSMERZSA-N 0.000 claims 1
• VRYALKFFQXWPIH-RANCGNPWSA-N (3r,4s,5r)-3,4,5,6-tetrahydroxy-2-tritiohexanal Chemical compound O=CC([3H])[C@@H](O)[C@H](O)[C@H](O)CO VRYALKFFQXWPIH-RANCGNPWSA-N 0.000 claims 1
• HSNZZMHEPUFJNZ-QMTIVRBISA-N D-keto-manno-heptulose Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)C(=O)CO HSNZZMHEPUFJNZ-QMTIVRBISA-N 0.000 claims 1
• 102000016267 Leptin Human genes 0.000 claims 1
• 108010092277 Leptin Proteins 0.000 claims 1
• 229920001991 Proanthocyanidin Polymers 0.000 claims 1
• QNVSXXGDAPORNA-UHFFFAOYSA-N Resveratrol Natural products OC1=CC=CC(C=CC=2C=C(O)C(O)=CC=2)=C1 QNVSXXGDAPORNA-UHFFFAOYSA-N 0.000 claims 1
• LUKBXSAWLPMMSZ-OWOJBTEDSA-N Trans-resveratrol Chemical group C1=CC(O)=CC=C1\C=C\C1=CC(O)=CC(O)=C1 LUKBXSAWLPMMSZ-OWOJBTEDSA-N 0.000 claims 1
• 239000003555 cannabinoid 1 receptor antagonist Substances 0.000 claims 1
• 229960004203 carnitine Drugs 0.000 claims 1
• 235000006486 human diet Nutrition 0.000 claims 1
• 230000000366 juvenile effect Effects 0.000 claims 1
• NRYBAZVQPHGZNS-ZSOCWYAHSA-N leptin Chemical compound O=C([C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC=1C2=CC=CC=C2NC=1)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CO)NC(=O)CNC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](N)CC(C)C)CCSC)N1CCC[C@H]1C(=O)NCC(=O)N[C@@H](CS)C(O)=O NRYBAZVQPHGZNS-ZSOCWYAHSA-N 0.000 claims 1
• 229940039781 leptin Drugs 0.000 claims 1
• AGBQKNBQESQNJD-UHFFFAOYSA-M lipoate Chemical compound [O-]C(=O)CCCCC1CCSS1 AGBQKNBQESQNJD-UHFFFAOYSA-M 0.000 claims 1
• 235000019136 lipoic acid Nutrition 0.000 claims 1
• XZWYZXLIPXDOLR-UHFFFAOYSA-N metformin Chemical compound CN(C)C(=N)NC(N)=N XZWYZXLIPXDOLR-UHFFFAOYSA-N 0.000 claims 1
• 229960003105 metformin Drugs 0.000 claims 1
• 239000003607 modifier Substances 0.000 claims 1
• 235000021283 resveratrol Nutrition 0.000 claims 1
• 229940016667 resveratrol Drugs 0.000 claims 1
• 229960002663 thioctic acid Drugs 0.000 claims 1