JP2013515676A5 - - Google Patents
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- Publication number
- JP2013515676A5 JP2013515676A5 JP2012530000A JP2012530000A JP2013515676A5 JP 2013515676 A5 JP2013515676 A5 JP 2013515676A5 JP 2012530000 A JP2012530000 A JP 2012530000A JP 2012530000 A JP2012530000 A JP 2012530000A JP 2013515676 A5 JP2013515676 A5 JP 2013515676A5
- Authority
- JP
- Japan
- Prior art keywords
- corneal endothelial
- pyrrolo
- benzamide
- pyridin
- aminoethyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 210000000399 corneal endothelial cell Anatomy 0.000 claims 6
- -1 1H-pyrrolo [2,3-b] pyridin-4-yl Chemical group 0.000 claims 5
- 150000003839 salts Chemical class 0.000 claims 5
- 210000004087 cornea Anatomy 0.000 claims 3
- 238000004519 manufacturing process Methods 0.000 claims 3
- 239000002318 adhesion promoter Substances 0.000 claims 2
- 239000003814 drug Substances 0.000 claims 2
- 230000003511 endothelial effect Effects 0.000 claims 2
- 239000003223 protective agent Substances 0.000 claims 2
- 229940124597 therapeutic agent Drugs 0.000 claims 2
- 206010048554 Endothelial dysfunction Diseases 0.000 claims 1
- 239000004480 active ingredient Substances 0.000 claims 1
- 230000021164 cell adhesion Effects 0.000 claims 1
- 238000012258 culturing Methods 0.000 claims 1
- 230000008694 endothelial dysfunction Effects 0.000 claims 1
- 239000003889 eye drop Substances 0.000 claims 1
- 239000001963 growth medium Substances 0.000 claims 1
- 239000007943 implant Substances 0.000 claims 1
- 239000007788 liquid Substances 0.000 claims 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2012530000A JP5750444B2 (ja) | 2009-12-29 | 2010-12-28 | 角膜内皮障害治療剤（ｙ−３９９８３） |
Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2009299180 | 2009-12-29 | ||
| JP2009299180 | 2009-12-29 | ||
| PCT/JP2010/071424 WO2011080984A1 (en) | 2009-12-29 | 2010-11-24 | Therapeutic agent (y - 39983 ) for corneal endothelial dysfunction |
| JPPCT/JP2010/071424 | 2010-11-24 | ||
| PCT/JP2010/073904 WO2011081221A1 (en) | 2009-12-29 | 2010-12-28 | Therapeutic agent (y - 39983 ) for corneal endothelial dysfunction |
| JP2012530000A JP5750444B2 (ja) | 2009-12-29 | 2010-12-28 | 角膜内皮障害治療剤（ｙ−３９９８３） |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015100969A Division JP2015155460A (ja) | 2009-12-29 | 2015-05-18 | 角膜内皮障害治療剤（ｙ−３９９８３） |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013515676A JP2013515676A (ja) | 2013-05-09 |
| JP2013515676A5 true JP2013515676A5 (https=) | 2014-02-13 |
| JP5750444B2 JP5750444B2 (ja) | 2015-07-22 |
Family
ID=43598277
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012530000A Expired - Fee Related JP5750444B2 (ja) | 2009-12-29 | 2010-12-28 | 角膜内皮障害治療剤（ｙ−３９９８３） |
| JP2015100969A Pending JP2015155460A (ja) | 2009-12-29 | 2015-05-18 | 角膜内皮障害治療剤（ｙ−３９９８３） |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015100969A Pending JP2015155460A (ja) | 2009-12-29 | 2015-05-18 | 角膜内皮障害治療剤（ｙ−３９９８３） |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20120288482A1 (https=) |
| EP (1) | EP2519237A1 (https=) |
| JP (2) | JP5750444B2 (https=) |
| KR (1) | KR20120099147A (https=) |
| CN (1) | CN102770136A (https=) |
| BR (1) | BR112012016128A8 (https=) |
| CA (1) | CA2785851A1 (https=) |
| MX (1) | MX2012007671A (https=) |
| RU (1) | RU2563141C2 (https=) |
| WO (2) | WO2011080984A1 (https=) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2858173C (en) * | 2011-12-06 | 2023-09-26 | Advanced Cell Technology, Inc. | Method of directed differentiation producing corneal endothelial cells, compositions thereof, and uses thereof |
| WO2015080297A1 (en) | 2013-11-27 | 2015-06-04 | Kyoto Prefectural Public University Corporation | Application of laminin to corneal endothelial cell culture |
| US10959997B2 (en) | 2013-12-27 | 2021-03-30 | Kyoto Prefectural Public University Corporation | Combined agent for cell therapy of corneal endothelial cell |
| CN106604730B (zh) * | 2014-09-24 | 2019-12-20 | 兴和株式会社 | 角膜厚度调节剂 |
| JP6770435B2 (ja) | 2014-10-31 | 2020-10-14 | 京都府公立大学法人 | ラミニンによる網膜および神経の新規治療 |
| RU2718062C2 (ru) * | 2014-10-31 | 2020-03-30 | Сэндзю Фармасьютикал Ко., Лтд. | Новое лечение роговицы с применением ламинина |
| EP3416658B1 (en) * | 2016-02-15 | 2023-03-22 | Kyoto Prefectural Public University Corporation | Human functional corneal endothelial cell and application thereof |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1195372A1 (en) | 1994-04-18 | 2002-04-10 | Mitsubishi Pharma Corporation | N-heterocyclic substituted benzamide derivatives with antihypertensive activity |
| US7109208B2 (en) | 2001-04-11 | 2006-09-19 | Senju Pharmaceutical Co., Ltd. | Visual function disorder improving agents |
| JP2004024852A (ja) | 2002-04-30 | 2004-01-29 | Amniotec:Kk | 角膜内皮様シート、及びその作製方法 |
| US7087237B2 (en) * | 2003-09-19 | 2006-08-08 | Advanced Ocular Systems Limited | Ocular solutions |
| US7485654B2 (en) * | 2004-06-03 | 2009-02-03 | Senju Pharmaceutical Co., Ltd. | Corneal perception recovery drug containing amide compound |
| WO2006057270A1 (ja) * | 2004-11-26 | 2006-06-01 | Asahi Kasei Pharma Corporation | 含窒素３環化合物 |
| JP4766653B2 (ja) * | 2005-01-28 | 2011-09-07 | 株式会社林原生物化学研究所 | 眼科用医薬組成物 |
| US20090062295A1 (en) * | 2005-03-10 | 2009-03-05 | Mitsubishi Pharma Corporation | Pharmaceutical Products |
| JP5255846B2 (ja) * | 2006-01-19 | 2013-08-07 | 千寿製薬株式会社 | 生体内で細胞増殖可能な角膜内皮製剤 |
| BRPI0714782A2 (pt) * | 2006-07-31 | 2013-07-16 | Senju Pharma Co | preparaÇço lÍquida aquosa contendo composto de amida |
| WO2009028631A1 (ja) | 2007-08-29 | 2009-03-05 | Senju Pharmaceutical Co., Ltd. | 角膜内皮細胞接着促進剤 |
| JP5251632B2 (ja) | 2008-05-13 | 2013-07-31 | 新日鐵住金株式会社 | 耐遅れ破壊特性に優れた高強度鋼材、高強度ボルト及びその製造方法 |
| JP2010071424A (ja) | 2008-09-19 | 2010-04-02 | Toyota Motor Corp | 変速機の制御装置 |
-
2010
- 2010-11-24 WO PCT/JP2010/071424 patent/WO2011080984A1/en not_active Ceased
- 2010-12-28 CN CN2010800649229A patent/CN102770136A/zh active Pending
- 2010-12-28 BR BR112012016128A patent/BR112012016128A8/pt not_active IP Right Cessation
- 2010-12-28 RU RU2012132443/15A patent/RU2563141C2/ru not_active IP Right Cessation
- 2010-12-28 KR KR1020127019919A patent/KR20120099147A/ko not_active Abandoned
- 2010-12-28 MX MX2012007671A patent/MX2012007671A/es active IP Right Grant
- 2010-12-28 CA CA2785851A patent/CA2785851A1/en not_active Abandoned
- 2010-12-28 JP JP2012530000A patent/JP5750444B2/ja not_active Expired - Fee Related
- 2010-12-28 EP EP10805660A patent/EP2519237A1/en not_active Withdrawn
- 2010-12-28 US US13/519,682 patent/US20120288482A1/en not_active Abandoned
- 2010-12-28 WO PCT/JP2010/073904 patent/WO2011081221A1/en not_active Ceased
-
2015
- 2015-05-18 JP JP2015100969A patent/JP2015155460A/ja active Pending
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