JP2013515013A5 - - Google Patents
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- JP2013515013A5 JP2013515013A5 JP2012545019A JP2012545019A JP2013515013A5 JP 2013515013 A5 JP2013515013 A5 JP 2013515013A5 JP 2012545019 A JP2012545019 A JP 2012545019A JP 2012545019 A JP2012545019 A JP 2012545019A JP 2013515013 A5 JP2013515013 A5 JP 2013515013A5
- Authority
- JP
- Japan
- Prior art keywords
- antibody
- amino acid
- acid sequence
- antibody fragment
- fragment according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 108010021625 Immunoglobulin Fragments Proteins 0.000 claims 23
- 102000008394 Immunoglobulin Fragments Human genes 0.000 claims 23
- 125000003275 alpha amino acid group Chemical group 0.000 claims 22
- 206010028980 Neoplasm Diseases 0.000 claims 3
- 201000011510 cancer Diseases 0.000 claims 3
- 108010047041 Complementarity Determining Regions Proteins 0.000 claims 2
- 108060003951 Immunoglobulin Proteins 0.000 claims 2
- 239000003153 chemical reaction reagent Substances 0.000 claims 2
- 201000010099 disease Diseases 0.000 claims 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 2
- 102000018358 immunoglobulin Human genes 0.000 claims 2
- 125000000539 amino acid group Chemical group 0.000 claims 1
- 239000000427 antigen Substances 0.000 claims 1
- 102000036639 antigens Human genes 0.000 claims 1
- 108091007433 antigens Proteins 0.000 claims 1
- 238000003745 diagnosis Methods 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 238000000034 method Methods 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU2009906286A AU2009906286A0 (en) | 2009-12-24 | Anti P2X7 receptor antibodies and fragments thereof | |
| AU2009906286 | 2009-12-24 | ||
| PCT/AU2010/001741 WO2011075789A1 (en) | 2009-12-24 | 2010-12-23 | Antibodies to non-functional oligomeric p2x7 receptors |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013515013A JP2013515013A (ja) | 2013-05-02 |
| JP2013515013A5 true JP2013515013A5 (cg-RX-API-DMAC7.html) | 2014-02-13 |
| JP5992831B2 JP5992831B2 (ja) | 2016-09-14 |
Family
ID=44194835
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012545019A Active JP5992831B2 (ja) | 2009-12-24 | 2010-12-23 | 非機能性オリゴマーｐ２ｘ７受容体に対する抗体 |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US8835609B2 (cg-RX-API-DMAC7.html) |
| EP (2) | EP2516470B1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP5992831B2 (cg-RX-API-DMAC7.html) |
| CN (1) | CN102762595B (cg-RX-API-DMAC7.html) |
| AU (1) | AU2010336032C1 (cg-RX-API-DMAC7.html) |
| BR (1) | BR112012015561B1 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2784345C (cg-RX-API-DMAC7.html) |
| ES (2) | ES2732021T3 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2011075789A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MY158262A (en) | 2001-01-17 | 2016-09-30 | Biosceptre (Aust) Pty Ltd | Diagnosis and treatments of cancers and other conditions |
| ATE542139T1 (de) | 2007-09-14 | 2012-02-15 | Biosceptre Int Ltd | Purinerge (p2x)-rezeptoren in extrazellulärer körperflüssigkeit |
| NZ583894A (en) | 2007-09-14 | 2013-01-25 | Biosceptre Int Ltd | Antibodies that bind to a non atp binding p2x7 receptor |
| CN102143978B (zh) | 2008-07-04 | 2015-02-18 | 生物权威国际有限公司 | 抗p2x7肽和表位 |
| ES2557456T3 (es) | 2009-08-20 | 2016-01-26 | Biosceptre (Aust) Pty Ltd | Anticuerpos anti-receptor P2X7 y fragmentos de los mismos |
| BR112012015561B1 (pt) | 2009-12-24 | 2019-11-12 | Biosceptre International Ltd | anticorpos dirigidos contra receptores p2x7 oligoméricos não funcionais |
| US9562094B2 (en) | 2010-09-10 | 2017-02-07 | Biosceptre (Aust) Pty Ltd | Companion animal treatments |
| BR112013033974A2 (pt) | 2011-07-01 | 2017-02-14 | Biosceptre Int Ltd | terapia de combinação |
| JPWO2014003137A1 (ja) * | 2012-06-27 | 2016-06-02 | 旭化成メディカル株式会社 | 高アフィニティー抗体、及びその製造方法 |
| AU2016240410B2 (en) * | 2015-04-02 | 2021-09-16 | Biosceptre (Aust) Pty Ltd | Pain treatment |
| CN108350462B (zh) | 2015-09-11 | 2022-05-27 | 生物权威（英国）有限公司 | 嵌合抗原受体及其用途 |
| WO2018071959A1 (en) | 2016-10-21 | 2018-04-26 | Biosceptre (Uk) Limited | Cytotoxic particles |
| EP3755327A4 (en) * | 2018-02-23 | 2021-11-24 | REMD Biotherapeutics, Inc. | CALCITONIN GENE-RELATED PEPTIDE ANTAGONIST ANTIBODIES (CGRP) |
| WO2019229296A1 (en) | 2018-05-29 | 2019-12-05 | Teknologian Tutkimuskeskus Vtt Oy | Anti-thyroid hormone (t4) recombinant antibody or antigen binding fragment |
| CN110054691B (zh) * | 2019-05-09 | 2021-09-07 | 潍坊医学院 | 一种抗人p2rx7单克隆抗体的杂交瘤细胞系 |
| US20220251187A1 (en) * | 2019-07-26 | 2022-08-11 | Biosceptre (Aust) Pty Ltd | P2x7 receptor targeted therapy |
| CA3211323A1 (en) * | 2021-03-11 | 2022-09-15 | Patrick Schlegel | Novel cell therapy system |
| US20240368282A1 (en) * | 2021-09-01 | 2024-11-07 | Biosceptre (Aust) Pty Ltd | Methods and compositions for stimulating immune activity |
Family Cites Families (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IE920765A1 (en) | 1991-03-12 | 1992-09-23 | Scripps Research Inst | Cell surface receptors homologous to coagulation factors v¹and viii |
| WO1995033048A2 (en) | 1994-05-27 | 1995-12-07 | Glaxo Group Limited | P2x receptors (purinoceptor family) |
| JPH11510393A (ja) | 1995-08-09 | 1999-09-14 | インスティチュート ナショナル ドゥ ラ セント エト ドゥ ラ リサーチェ メディカル | 白血病マーカーとしておよび乳癌の予後において有用な単離された核酸分子 |
| WO1997041222A1 (en) | 1996-04-30 | 1997-11-06 | Smithkline Beecham P.L.C. | HUMAN P2x4 RECEPTOR SPLICE-VARIANTS |
| US6303338B1 (en) | 1996-08-16 | 2001-10-16 | Human Genome Sciences, Inc. | Pancreas-derived plasminogen activator inhibitor |
| US6306393B1 (en) | 1997-03-24 | 2001-10-23 | Immunomedics, Inc. | Immunotherapy of B-cell malignancies using anti-CD22 antibodies |
| JP3885177B2 (ja) | 1997-03-26 | 2007-02-21 | 大塚製薬株式会社 | ヒト遺伝子 |
| US6133434A (en) | 1997-04-28 | 2000-10-17 | Glaxo Group Limited | Purinergic receptor |
| JP4855577B2 (ja) | 1998-06-01 | 2012-01-18 | アジェンシス，インコーポレイテッド | ヒト癌で発現される新規蛇行性膜貫通抗原およびその使用 |
| DE19829473C2 (de) | 1998-07-01 | 2000-08-10 | Magnus Von Knebel Doeberitz Ch | Verfahren zur frühen Diagnose von Carcinomen |
| WO2000050458A1 (en) | 1999-02-26 | 2000-08-31 | Smithkline Beecham Corporation | Cloning of a p2y-like 7tm receptor (axor17) |
| AUPP991199A0 (en) | 1999-04-21 | 1999-05-13 | University Of Sydney, The | Methods for diagnosing pre-cancerous and cancerous conditions |
| AU1339701A (en) | 1999-10-22 | 2001-05-08 | Lifespan Biosciences, Inc. | Anti-cancer nucleic acid and protein targets |
| AUPR201500A0 (en) | 2000-12-11 | 2001-01-11 | Biosceptre Pty Ltd | Methods for identifying pre-neoplastic and neoplastic states in mammals |
| MY158262A (en) | 2001-01-17 | 2016-09-30 | Biosceptre (Aust) Pty Ltd | Diagnosis and treatments of cancers and other conditions |
| CA2459348C (en) * | 2001-09-03 | 2013-06-18 | Intreat Pty Limited | Antibodies to non-functional p2x7receptor, diagnosis and treatment of cancers and other conditions |
| MXPA05011008A (es) | 2003-04-17 | 2006-03-08 | Affectis Pharmaceuticals Ag | Medios y metodos para diagnosticar y tratar trastornos afectivos. |
| CA2607541A1 (en) | 2005-05-05 | 2006-12-28 | Medicure International Inc. | Inhibition of atp-mediated, p2x7 dependent pathways by pyridoxal-5-phosphaste and vitamin b6 related compounds |
| US7767789B2 (en) | 2005-06-02 | 2010-08-03 | University Hopitals of Cleveland | Truncated proteins as cancer markers |
| EP1929305A2 (en) | 2005-08-31 | 2008-06-11 | Cell Signaling Technology, Inc. | Reagents for the detection of protein phosphorylation in leukemia signaling pathways |
| US20100036101A1 (en) | 2006-10-10 | 2010-02-11 | Angus Gidley-Baird | Antibodies against non functional p2x7 receptor |
| WO2008043145A1 (en) * | 2006-10-10 | 2008-04-17 | Biosceptre International Limited | Hybridomas producing antibodies against non functional p2x7 receptor |
| NZ583894A (en) | 2007-09-14 | 2013-01-25 | Biosceptre Int Ltd | Antibodies that bind to a non atp binding p2x7 receptor |
| ATE542139T1 (de) | 2007-09-14 | 2012-02-15 | Biosceptre Int Ltd | Purinerge (p2x)-rezeptoren in extrazellulärer körperflüssigkeit |
| CN102143978B (zh) | 2008-07-04 | 2015-02-18 | 生物权威国际有限公司 | 抗p2x7肽和表位 |
| ES2557456T3 (es) | 2009-08-20 | 2016-01-26 | Biosceptre (Aust) Pty Ltd | Anticuerpos anti-receptor P2X7 y fragmentos de los mismos |
| BR112012015561B1 (pt) | 2009-12-24 | 2019-11-12 | Biosceptre International Ltd | anticorpos dirigidos contra receptores p2x7 oligoméricos não funcionais |
| US8828944B2 (en) | 2010-04-22 | 2014-09-09 | Institut Gustave Roussy | Compounds and uses thereof to induce an immunogenic cancer cell death in a subject |
| US9562094B2 (en) | 2010-09-10 | 2017-02-07 | Biosceptre (Aust) Pty Ltd | Companion animal treatments |
| BR112013033974A2 (pt) | 2011-07-01 | 2017-02-14 | Biosceptre Int Ltd | terapia de combinação |
-
2010
- 2010-12-23 BR BR112012015561-0A patent/BR112012015561B1/pt active IP Right Grant
- 2010-12-23 ES ES17209838T patent/ES2732021T3/es active Active
- 2010-12-23 CN CN201080063868.6A patent/CN102762595B/zh active Active
- 2010-12-23 US US13/518,382 patent/US8835609B2/en active Active
- 2010-12-23 EP EP10838429.8A patent/EP2516470B1/en active Active
- 2010-12-23 JP JP2012545019A patent/JP5992831B2/ja active Active
- 2010-12-23 CA CA2784345A patent/CA2784345C/en active Active
- 2010-12-23 AU AU2010336032A patent/AU2010336032C1/en active Active
- 2010-12-23 EP EP17209838.6A patent/EP3321285B1/en active Active
- 2010-12-23 ES ES10838429.8T patent/ES2667003T3/es active Active
- 2010-12-23 WO PCT/AU2010/001741 patent/WO2011075789A1/en not_active Ceased
-
2014
- 2014-08-11 US US14/456,898 patent/US9428587B2/en active Active