JP2013512909A - ジジフス・ジョアゼイロの抽出物を含有する口腔用組成物および関連する方法 - Google Patents
ジジフス・ジョアゼイロの抽出物を含有する口腔用組成物および関連する方法 Download PDFInfo
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- BEPFTJCKIFCNJT-UHFFFAOYSA-N COc(ccc(CCC(CC(CCc(cc1)cc(OC)c1O)=O)=O)c1)c1O Chemical compound COc(ccc(CCC(CC(CCc(cc1)cc(OC)c1O)=O)=O)c1)c1O BEPFTJCKIFCNJT-UHFFFAOYSA-N 0.000 description 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/61—Myrtaceae (Myrtle family), e.g. teatree or eucalyptus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/30—Zinc; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A—HUMAN NECESSITIES
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/21—Amaranthaceae (Amaranth family), e.g. pigweed, rockwort or globe amaranth
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- A61K36/18—Magnoliophyta (angiosperms)
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- A61K36/18—Magnoliophyta (angiosperms)
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- A61K36/18—Magnoliophyta (angiosperms)
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- A61K36/18—Magnoliophyta (angiosperms)
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- A61K36/57—Magnoliaceae (Magnolia family)
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- A61K36/18—Magnoliophyta (angiosperms)
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- A61K36/18—Magnoliophyta (angiosperms)
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- A61K36/18—Magnoliophyta (angiosperms)
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
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- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9794—Liliopsida [monocotyledons]
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- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
Abstract
【選択図】なし
Description
[0001] この出願は2009年12月4日に出願された米国仮特許出願第61/266,558号に対して優先権を主張し、それを本明細書に援用する。
[0009] ブラジル北東部に固有の樹木であるジジフス・ジョアゼイロ(Zizyphus joazeiro)の樹木の樹皮からの抽出物は抗真菌活性を有することが報告されており、シャンプーおよび石鹸において用いられてきた。その樹皮の抽出物は、トリテルペンサポニン類、ベツリン酸(betulinic acid)、ウルソール酸(ursolic acid)およびアルフィトール酸類(alphitolic acids)が含まれる多くの化学物質を含有していることが報告されている。これらの化合物のいくつかは抗細菌活性を有することが報告されてきた。Schuhly, W., et al., “ジジフス・ジョアゼイロからの抗細菌活性を有する新規トリテルペノイド類” Planta-Med., 65(8): pp 740-743 (Dec. 1999); Schuhly, W., et al., “ジジフス・ジョアゼイロからの新規トリテルペンサポニン類” Helvetica Chim. Acta, 83(7): pp 1509-1516 (July, 2000); Taylor, L., THE HEALING POWER OF RAINFOREST HERBS, Raintree Nutrition, Inc.,ネバダ州カーソンシティ(2005); Watanabe, E., et al., “黄色ブドウ球菌に対する塩化セチルピリジニウムに基づくマウスウォッシュの最大阻害希釈の決定:インビトロでの研究” J. Appl. Oral Sci., 16(4), pp 275-279 (2008)。
[0044] 本開示の特定の観点において、口腔用組成物は場合により、商標名SABIWHITE(登録商標)の下でSabinsa Corp.から入手可能なテトラヒドロクルクミノイドが含まれるC.ロンガ由来の商業的に入手可能な抽出物を含み、それは以下の代表的な構造を有すると信じられている:
[0102] 以下の成分を用いて練り歯磨き配合物を調製する:
[0104] 以下の成分を用いてマウスウォッシュ配合物を調製する:
Claims (10)
- 以下:
ジジフス・ジョアゼイロ(Zizyphus joazeiro)からの抽出物およびジジフス・ジョアゼイロからの抽出物以外の天然抽出物を含む抽出物の組み合わせ;ならびに
口に許容できるキャリヤー
を含む、口腔用組成物。 - 0.01重量%〜5重量%のその抽出物の組み合わせを含む、請求項1に記載の組成物。
- 0.1重量%〜2重量%のその抽出物の組み合わせを含む、請求項2に記載の組成物。
- そのジジフス・ジョアゼイロからの抽出物以外の天然抽出物が、オレガノ(oregano)、マグノリア、クランベリー、ローズマリー、ツバキ(Camellia)、モリン(morin)、ジンギベル・オフィキナレ(zingiber officinale)、ミリスチカ・フラグランス(Myristica fragrans)、ピューニカ・グラナツム(Punica granatum)、ガルシニア・マンゴスターナL(Garcinia mangostana L)、ジャバラ(Jabara)、アザディラクタ・インディカ(Azadirachta indica)、アカシア(Acacia)、ウーロン茶、ジュグランス・レジア(Juglans regia)、ザントクシルム・アラントゥム(Zanthoxylum alantum)、ミムソプス・エレンギ(Mimusops elengi)、トロロアオイモドキ(Hibiscus abelmoschus)、アーユルヴェーダ(Ayurvedic)、カラパ・プロセラ(Carapa procera)、セネガルマホガニー(Khaya senegalensis)、サルバドラ・ペルシカ(Salvadora persica)、ウリ科(Cucurbitaceae)(コロシント(Citrullus colocynthis))、アカシア・カテキュー(Acacia catechu)、アカシア・ニロティカ(Acacia nilotica)、アキラテス・アスペラ(Achyrathes aspera)、アザディラクタ・インディカ、アリストロキア・ブラクテオレート(Aristolochia bracteolate)、シナモムム・カンフォーラ(Cinnamomum camphora)、シナモムム・ベルム(Cinnamomum verum)、クルクマ・ロンガ(Curcuma longa)、ユーカリプタス・グロブルス(Eucalyptus globulus)、フィカス・ベンガレンシス(Ficus bengalensis)、ジュグランス・レジア、マドフカ・ロンギフォリア(Madhuca longifolia)、ミムソプス・エレンギ、オシマム・サンクタム(Ocimum sanctum)、ウーロン茶(Oolonga tea)、ピペルベテル(Piper betel)の葉、ピペル・ロングム(Piper longum)、ピペル・ニグルム(Piper nigrum)、ポテンチラ・フルゲンス(Potentilla fulgens)、シジギウム・アロマティクム(Syzygium aromaticum)、スピランテス・カルバ(Spilanthes calva)、バクシニウム・マクロカルポン(Vaccinium macrocarpon)、ザントクシルム・アルマトゥム(Zanthoxylum armatum)の抽出物、およびそれらの混合物からなるグループから選択される1種類以上の天然抽出物である、いずれかの前記の請求項に記載の組成物。
- さらに、フェノール化合物、スズイオン類、亜鉛イオン類、およびそれらの混合物から選択される追加の抗細菌剤を含む、いずれかの前記の請求項に記載の組成物。
- その亜鉛イオン類が酢酸亜鉛、クエン酸亜鉛、グルコン酸亜鉛、グリシン亜鉛、酸化亜鉛、硫酸亜鉛、クエン酸亜鉛ナトリウム、およびそれらの混合物からなるグループから選択される1種類以上の亜鉛を含有する化合物により提供される、請求項5に記載の組成物。
- その組成物がさらに湿潤剤、研磨剤、抗齲食剤、抗歯石または歯石制御剤、陰イオン性カルボキシレートポリマー類、粘度修正剤、界面活性剤、香味料、顔料、およびそれらの混合物からなるグループから選択される少なくとも1種類の追加の構成要素を含む、いずれかの前記の請求項に記載の組成物。
- その組成物が:粉末;練り歯磨きまたは歯用ゲル;歯周用ゲル;歯の表面に塗布するのに適した液体;チューインガム;溶解可能な、部分的に溶解可能な、または溶解不能な薄膜または細片;ビーズ、ウェファー;ワイプまたはタオレット;インプラント;マウスリンス、泡状物質、およびデンタルフロスからなるグループから選択される形の歯磨剤である、いずれかの前記の請求項に記載の組成物。
- それを必要とする患者の口腔に請求項1〜8のいずれかに記載の組成物を投与することを含む、口腔の軟組織の疾患または病気を処置する方法。
- その疾患または病気が口内乾燥症である、請求項9に記載の方法。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US26655809P | 2009-12-04 | 2009-12-04 | |
US61/266,558 | 2009-12-04 | ||
PCT/US2010/058468 WO2011068815A1 (en) | 2009-12-04 | 2010-12-01 | Oral compositions containing extracts of zizyphus joazeiro and related methods |
Publications (1)
Publication Number | Publication Date |
---|---|
JP2013512909A true JP2013512909A (ja) | 2013-04-18 |
Family
ID=43530018
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2012542140A Pending JP2013512909A (ja) | 2009-12-04 | 2010-12-01 | ジジフス・ジョアゼイロの抽出物を含有する口腔用組成物および関連する方法 |
Country Status (15)
Country | Link |
---|---|
US (1) | US20120237455A1 (ja) |
EP (2) | EP2506934A1 (ja) |
JP (1) | JP2013512909A (ja) |
CN (1) | CN102762260A (ja) |
AR (1) | AR079275A1 (ja) |
AU (1) | AU2010326137B2 (ja) |
BR (1) | BR112012013193A2 (ja) |
CA (1) | CA2779708A1 (ja) |
CO (1) | CO6541602A2 (ja) |
MX (1) | MX2012005421A (ja) |
MY (1) | MY150855A (ja) |
RU (1) | RU2012127797A (ja) |
TW (1) | TW201200161A (ja) |
WO (1) | WO2011068815A1 (ja) |
ZA (1) | ZA201203509B (ja) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
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CN104147240A (zh) * | 2014-07-10 | 2014-11-19 | 南京中医药大学 | 一种用于抗菌镇痛的中药组合物及其制备方法和应用 |
Families Citing this family (27)
Publication number | Priority date | Publication date | Assignee | Title |
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CN102579644B (zh) * | 2012-03-13 | 2013-09-18 | 河南中医学院 | 复方山楂叶总黄酮滴丸及其制备方法 |
US9517249B2 (en) | 2012-11-26 | 2016-12-13 | Access Business Group International Llc | Antioxidant dietary supplement and related method |
AU2012397210B2 (en) * | 2012-12-20 | 2016-03-10 | Colgate-Palmolive Company | Oral care composition containing ionic liquids |
EP2934470B1 (en) * | 2012-12-20 | 2017-06-14 | Colgate-Palmolive Company | Oral care composition containing ionic liquids |
WO2014098871A2 (en) * | 2012-12-20 | 2014-06-26 | Colgate-Palmolive Company | Oral care composition containing ionic liquids |
MX2015007879A (es) * | 2012-12-20 | 2015-09-21 | Colgate Palmolive Co | Composicion para el cuidado oral. |
MX339086B (es) | 2013-06-20 | 2016-05-09 | Inmolecule Internat Ltd | Nanomaterial de dioxido de titanio nanoparticulado modificado con grupos funcionales y con extractos citricos adsorbidos en la superficie para la eliminacion de amplio espectro de microorganismos. |
CN104510867A (zh) * | 2013-10-02 | 2015-04-15 | 青岛锦涟鑫商贸有限公司 | 一种中药杀菌牙粉 |
CN104510868A (zh) * | 2013-10-04 | 2015-04-15 | 青岛锦涟鑫商贸有限公司 | 一种中草药杀菌牙粉 |
CN106794120A (zh) * | 2014-09-01 | 2017-05-31 | 高露洁-棕榄公司 | 具有精油的含锌组合物 |
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ZA201203509B (en) | 2014-10-29 |
CN102762260A (zh) | 2012-10-31 |
TW201200161A (en) | 2012-01-01 |
CO6541602A2 (es) | 2012-10-16 |
MX2012005421A (es) | 2012-06-14 |
AU2010326137A1 (en) | 2012-05-24 |
US20120237455A1 (en) | 2012-09-20 |
BR112012013193A2 (pt) | 2016-03-01 |
AR079275A1 (es) | 2012-01-04 |
RU2012127797A (ru) | 2014-01-20 |
AU2010326137B2 (en) | 2013-05-30 |
EP2506934A1 (en) | 2012-10-10 |
CA2779708A1 (en) | 2011-06-09 |
WO2011068815A1 (en) | 2011-06-09 |
EP2689807A1 (en) | 2014-01-29 |
MY150855A (en) | 2014-03-14 |
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