JP2013511526A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2013511526A5 JP2013511526A5 JP2012539987A JP2012539987A JP2013511526A5 JP 2013511526 A5 JP2013511526 A5 JP 2013511526A5 JP 2012539987 A JP2012539987 A JP 2012539987A JP 2012539987 A JP2012539987 A JP 2012539987A JP 2013511526 A5 JP2013511526 A5 JP 2013511526A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- halogen
- agent
- substituted
- combination
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US26234209P | 2009-11-18 | 2009-11-18 | |
| US61/262,342 | 2009-11-18 | ||
| US29203210P | 2010-01-04 | 2010-01-04 | |
| US61/292,032 | 2010-01-04 | ||
| PCT/US2010/056942 WO2011062939A1 (en) | 2009-11-18 | 2010-11-17 | Methods and compositions for treating solid tumors and other malignancies |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2013511526A JP2013511526A (ja) | 2013-04-04 |
| JP2013511526A5 true JP2013511526A5 (enExample) | 2015-06-11 |
Family
ID=43384585
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012539987A Ceased JP2013511526A (ja) | 2009-11-18 | 2010-11-17 | 固形腫瘍及びその他の悪性腫瘍を治療するための方法及び組成物 |
Country Status (18)
| Country | Link |
|---|---|
| US (2) | US20120232087A1 (enExample) |
| EP (1) | EP2501370A1 (enExample) |
| JP (1) | JP2013511526A (enExample) |
| KR (1) | KR20120107962A (enExample) |
| CN (2) | CN104224791A (enExample) |
| AU (1) | AU2010322114B2 (enExample) |
| BR (1) | BR112012011823A2 (enExample) |
| CA (1) | CA2781210A1 (enExample) |
| CL (1) | CL2012001271A1 (enExample) |
| IL (1) | IL219636A0 (enExample) |
| MA (1) | MA33739B1 (enExample) |
| MX (1) | MX2012005695A (enExample) |
| NZ (1) | NZ599964A (enExample) |
| PH (1) | PH12012500911A1 (enExample) |
| RU (1) | RU2012125152A (enExample) |
| TN (1) | TN2012000205A1 (enExample) |
| WO (1) | WO2011062939A1 (enExample) |
| ZA (1) | ZA201203325B (enExample) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2013511541A (ja) | 2009-11-18 | 2013-04-04 | プレキシコン インコーポレーテッド | キナーゼ調節のための化合物および方法、ならびにその適応 |
| US20140094461A1 (en) * | 2011-06-02 | 2014-04-03 | Novartis Ag | Biomarkers for hedgehog inhibitor therapy |
| WO2013106812A1 (en) * | 2012-01-12 | 2013-07-18 | Board Of Regents, The University Of Texas System | Personalized medicine for the prediction of therapy targeting the hedgehog pathway |
| KR20150105302A (ko) | 2012-11-05 | 2015-09-16 | 난트 홀딩스 아이피, 엘엘씨 | 헤지 호그 신호 경로의 억제제로서 환상 술폰아미드 함유 유도체 |
| CN103524535B (zh) * | 2013-10-16 | 2016-07-13 | 苏州云轩医药科技有限公司 | 具有刺猬通路拮抗剂活性的胺基噻唑-吡啶杂环化合物 |
| AU2018205253B2 (en) | 2017-01-06 | 2022-01-13 | Palvella Therapeutics, Inc. | Anhydrous compositions of mTOR inhibitors and methods of use |
| FI3700902T3 (fi) | 2017-10-27 | 2023-05-25 | Boehringer Ingelheim Int | TRPC6:n inhibiittoreita |
| EP3817743A4 (en) * | 2018-07-02 | 2022-07-06 | Palvella Therapeutics, Inc. | ANHYDROUS COMPOSITIONS OF MTOR INHIBITORS AND METHODS OF USE |
| WO2020061584A1 (en) * | 2018-09-21 | 2020-03-26 | Msb Holdings, Inc. | Taste-masked dosage forms |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9221220D0 (en) | 1992-10-09 | 1992-11-25 | Sandoz Ag | Organic componds |
| KR101464384B1 (ko) | 2005-11-22 | 2014-11-21 | 쿠도스 파마슈티칼스 리미티드 | ｍＴＯＲ 억제제로서 피리도피리미딘, 피라조피리미딘 및피리미도피리미딘 유도체 |
| UA93548C2 (uk) * | 2006-05-05 | 2011-02-25 | Айерем Елелсі | Сполуки та композиції як модулятори хеджхогівського сигнального шляху |
| PT2057156T (pt) | 2006-08-23 | 2017-05-04 | Kudos Pharm Ltd | Derivados de 2-metilmorfolina pirido-, pirazo- e pirimidopirimidina como inibidores de mtor |
| EP2137162B1 (en) * | 2007-03-15 | 2018-08-01 | Novartis AG | Organic compounds and their uses |
| ES2569941T3 (es) * | 2007-06-07 | 2016-05-13 | Novartis Ag | Derivados de bifenilcarboxamida como moduladores de la ruta de hedgehog |
| ES2505091T3 (es) * | 2007-06-25 | 2014-10-09 | Amgen Inc. | Compuestos, composiciones y métodos de uso de ftalazina |
| EP2249844A1 (en) * | 2008-03-12 | 2010-11-17 | Ludwig-Maximilians-Universität München | Active substance combination with gemcitabine for the treatment of epithelial cancer |
| US7981892B2 (en) * | 2008-04-29 | 2011-07-19 | Eli Lilly And Company | Disubstituted phthalazine hedgehog pathway antagonists |
| US20100041663A1 (en) * | 2008-07-18 | 2010-02-18 | Novartis Ag | Organic Compounds as Smo Inhibitors |
-
2010
- 2010-11-17 KR KR1020127015545A patent/KR20120107962A/ko not_active Withdrawn
- 2010-11-17 BR BR112012011823A patent/BR112012011823A2/pt not_active IP Right Cessation
- 2010-11-17 AU AU2010322114A patent/AU2010322114B2/en not_active Ceased
- 2010-11-17 JP JP2012539987A patent/JP2013511526A/ja not_active Ceased
- 2010-11-17 EP EP10782767A patent/EP2501370A1/en not_active Withdrawn
- 2010-11-17 CA CA2781210A patent/CA2781210A1/en not_active Abandoned
- 2010-11-17 WO PCT/US2010/056942 patent/WO2011062939A1/en not_active Ceased
- 2010-11-17 PH PH1/2012/500911A patent/PH12012500911A1/en unknown
- 2010-11-17 US US13/509,857 patent/US20120232087A1/en not_active Abandoned
- 2010-11-17 MX MX2012005695A patent/MX2012005695A/es not_active Application Discontinuation
- 2010-11-17 CN CN201410410334.6A patent/CN104224791A/zh active Pending
- 2010-11-17 NZ NZ599964A patent/NZ599964A/en not_active IP Right Cessation
- 2010-11-17 CN CN2010800517592A patent/CN102665700A/zh active Pending
- 2010-11-17 RU RU2012125152/15A patent/RU2012125152A/ru unknown
-
2012
- 2012-05-07 ZA ZA2012/03325A patent/ZA201203325B/en unknown
- 2012-05-07 IL IL219636A patent/IL219636A0/en unknown
- 2012-05-07 TN TNP2012000205A patent/TN2012000205A1/en unknown
- 2012-05-11 MA MA34856A patent/MA33739B1/fr unknown
- 2012-05-16 CL CL2012001271A patent/CL2012001271A1/es unknown
-
2014
- 2014-10-09 US US14/510,713 patent/US20150025074A1/en not_active Abandoned
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ES2609767T3 (es) | Combinaciones de un inhibidor de PI3K y un inhibidor de MEK | |
| Nonnenmacher et al. | RIST: A potent new combination therapy for glioblastoma | |
| RU2508110C2 (ru) | КОМБИНАЦИЯ (А) ИНГИБИТОРА ФОСФОИНОЗИТ-3-КИНАЗЫ И (Б) МОДУЛЯТОРА ПУТИ Ras/Raf/Mek | |
| JP6648040B2 (ja) | がん治療のための併用療法としてのエリブリン及びポリ（ａｄｐリボース）ポリメラーゼ（ｐａｒｐ）阻害剤の使用 | |
| JP5579715B2 (ja) | ｃｄｋ阻害剤および抗悪性腫瘍剤を含む治療用組合せ | |
| AU2015289504B2 (en) | Treatment of cancer with a combination of radiation, cerium oxide nanoparticles, and a chemotherapeutic agent | |
| ES2861180T3 (es) | Derivados de 2-hidroxi-1-{4-[(4-fenil)fenil]carbonil}piperazin-1-il}etan-1-ona y compuestos relacionados como inhibidores de sintasa de ácido graso (FASN) para el tratamiento del cáncer | |
| TW202446772A (zh) | Ｓｔｉｎｇ促效化合物 | |
| JP2022145800A (ja) | 静止細胞標的化およびｅｇｆｒ阻害剤を用いた新生物の処置のための組み合わせ | |
| ATE551060T1 (de) | Zusammensetzungen und verfahren zur behandlung von neovaskulären erkrankungen | |
| JP2018510869A (ja) | 置換２，３−ジヒドロイミダゾ［１，２−ｃ］キナゾリンを含んでいる組合せ | |
| AU2013341271A1 (en) | Combination therapy | |
| JP5440985B2 (ja) | メラノーマの治療 | |
| JP2020523354A5 (enExample) | ||
| JP2013511526A (ja) | 固形腫瘍及びその他の悪性腫瘍を治療するための方法及び組成物 | |
| CA3253034A1 (en) | METHODS FOR TREATMENT OF MYELOID MALIGNITIS USING A BCL-2 INHIBITOR | |
| ES2685974T3 (es) | Derivados de cefalosporina para tratar el cáncer | |
| ITMI20042475A1 (it) | Uso di derivati tiazolidinonici come agenti terapeutici | |
| MX2023011814A (es) | Derivados heterociclicos, composiciones farmaceuticas y su uso en el tratamiento o la mejora del cancer. | |
| CN112237579A (zh) | 药物组合及其用途 | |
| CN102105148B (zh) | 包含aurora激酶抑制剂和抗肿瘤药的治疗组合 | |
| Kasper et al. | Treatment of patients with advanced soft tissue sarcoma: disappointment or challenge? | |
| RU2012123970A (ru) | Тивозаниб и темсиролимус в комбинации | |
| RU2009128186A (ru) | Производные трициклических аминов в качестве ингибиторов тирозинкиназы | |
| JP2013510899A5 (enExample) |