JP2013509432A5 - - Google Patents
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- JP2013509432A5 JP2013509432A5 JP2012537122A JP2012537122A JP2013509432A5 JP 2013509432 A5 JP2013509432 A5 JP 2013509432A5 JP 2012537122 A JP2012537122 A JP 2012537122A JP 2012537122 A JP2012537122 A JP 2012537122A JP 2013509432 A5 JP2013509432 A5 JP 2013509432A5
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- JP
- Japan
- Prior art keywords
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- residues
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- peptide
- Prior art date
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- 108090000765 processed proteins & peptides Proteins 0.000 claims 21
- 125000000539 amino acid group Chemical group 0.000 claims 4
- 102000001189 Cyclic Peptides Human genes 0.000 claims 2
- 108010069514 Cyclic Peptides Proteins 0.000 claims 2
- 125000001165 hydrophobic group Chemical group 0.000 claims 2
- 239000008194 pharmaceutical composition Substances 0.000 claims 2
- 150000008574 D-amino acids Chemical group 0.000 claims 1
- 208000029433 Herpesviridae infectious disease Diseases 0.000 claims 1
- 241000701024 Human betaherpesvirus 5 Species 0.000 claims 1
- 108010029389 Simplexvirus glycoprotein B Proteins 0.000 claims 1
- 125000002777 acetyl group Chemical group [H]C([H])([H])C(*)=O 0.000 claims 1
- 150000001412 amines Chemical class 0.000 claims 1
- 125000003277 amino group Chemical group 0.000 claims 1
- 210000004899 c-terminal region Anatomy 0.000 claims 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 claims 1
- 125000001295 dansyl group Chemical group [H]C1=C([H])C(N(C([H])([H])[H])C([H])([H])[H])=C2C([H])=C([H])C([H])=C(C2=C1[H])S(*)(=O)=O 0.000 claims 1
- 239000003085 diluting agent Substances 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 102000004196 processed proteins & peptides Human genes 0.000 claims 1
- 238000006467 substitution reaction Methods 0.000 claims 1
- 239000011885 synergistic combination Substances 0.000 claims 1
- -1 t-butyloxycarbonyl group Chemical group 0.000 claims 1
- 239000003981 vehicle Substances 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US28011209P | 2009-10-30 | 2009-10-30 | |
| US61/280,112 | 2009-10-30 | ||
| PCT/US2010/054743 WO2011053798A2 (en) | 2009-10-30 | 2010-10-29 | Peptide compositions and methods for inhibiting herpesvirus infection |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016014209A Division JP6209228B2 (ja) | 2009-10-30 | 2016-01-28 | ヘルペスウイルス感染を阻害するペプチド組成物および方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2013509432A JP2013509432A (ja) | 2013-03-14 |
| JP2013509432A5 true JP2013509432A5 (https=) | 2013-12-19 |
Family
ID=43923008
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012537122A Pending JP2013509432A (ja) | 2009-10-30 | 2010-10-29 | ヘルペスウイルス感染を阻害するペプチド組成物および方法 |
| JP2016014209A Expired - Fee Related JP6209228B2 (ja) | 2009-10-30 | 2016-01-28 | ヘルペスウイルス感染を阻害するペプチド組成物および方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016014209A Expired - Fee Related JP6209228B2 (ja) | 2009-10-30 | 2016-01-28 | ヘルペスウイルス感染を阻害するペプチド組成物および方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US8802106B2 (https=) |
| EP (1) | EP2493911B1 (https=) |
| JP (2) | JP2013509432A (https=) |
| AU (1) | AU2010313339B2 (https=) |
| CA (1) | CA2779459A1 (https=) |
| WO (1) | WO2011053798A2 (https=) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SG189176A1 (en) * | 2010-10-15 | 2013-05-31 | Glaxosmithkline Biolog Sa | Cytomegalovirus gb antigen |
| GB201312133D0 (en) * | 2013-07-05 | 2013-08-21 | Univ Birmingham | Immunotherapy |
| AU2014362234B2 (en) * | 2013-12-11 | 2019-09-12 | The Henry M. Jackson Foundation For The Advancement Of Military Medicine, Inc. | Human herpesvirus trimeric glycoprotein B, protein complexes comprising trimeric gB and their use as vaccines |
| US10611800B2 (en) | 2016-03-11 | 2020-04-07 | Pfizer Inc. | Human cytomegalovirus gB polypeptide |
| US11390661B2 (en) | 2016-06-27 | 2022-07-19 | Aicuris Anti-Infective Cures Gmbh | HCMV entry inhibitors |
| US11629172B2 (en) | 2018-12-21 | 2023-04-18 | Pfizer Inc. | Human cytomegalovirus gB polypeptide |
| CN111675752B (zh) * | 2020-03-16 | 2023-07-07 | 成都奥达生物科技有限公司 | 一种冠状病毒膜融合抑制剂及其药物用途 |
| TWI810589B (zh) | 2020-06-21 | 2023-08-01 | 美商輝瑞股份有限公司 | 人巨細胞病毒糖蛋白Ｂ（ｇＢ）多肽 |
| JP2024508799A (ja) * | 2021-02-24 | 2024-02-28 | ファイザー・インク | ヒトサイトメガロウイルス糖タンパク質ｂポリペプチドにおける新規創薬可能領域およびその使用方法 |
| CN115894708B (zh) * | 2022-08-16 | 2023-10-10 | 青岛大学 | 一种人巨细胞病毒抗原表位嵌合肽及其应用 |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1335429C (en) * | 1986-03-07 | 1995-05-02 | Geoffrey L. Smith | Processes for the production of hcmv glycoproteins, antibodies thereto and hcmv vaccines, and recombinant vectors therefor |
| JP2607712B2 (ja) * | 1988-01-29 | 1997-05-07 | カイロン コーポレイション | 組換えｃｍｖ中和タンパク |
| US5514577A (en) * | 1990-02-26 | 1996-05-07 | Isis Pharmaceuticals, Inc. | Oligonucleotide therapies for modulating the effects of herpes viruses |
| US5633230A (en) * | 1990-10-24 | 1997-05-27 | Allelix Biopharmaceuticals, Inc. | Treatment of cytomegalovirus infection |
| US5831001A (en) * | 1990-10-24 | 1998-11-03 | Allelix Biopharmaceuticals Inc. | Treatment of herpesvirus infection |
| US5464933A (en) | 1993-06-07 | 1995-11-07 | Duke University | Synthetic peptide inhibitors of HIV transmission |
| GB9409962D0 (en) * | 1994-05-18 | 1994-07-06 | Smithkline Beecham Biolog | Novel compounds |
| CA2295933A1 (en) * | 1997-07-03 | 1999-01-14 | Smithkline Beecham Corporation | Compounds and methods for treating and screening viral reactivation |
| US20030036181A1 (en) * | 2000-06-30 | 2003-02-20 | Okkels Jens Sigurd | Peptide extended glycosylated polypeptides |
| FR2818279B1 (fr) * | 2000-12-15 | 2005-02-25 | Univ Paris Curie | Peptide de la glycoproteine b de l'herpesvirus humain 7 utilisable notamment dans un test serologique elisa |
| AUPR593101A0 (en) * | 2001-06-26 | 2001-07-19 | Council Of The Queensland Institute Of Medical Research, The | Cytomegalovirus t cell epitopes |
| WO2004058166A2 (en) * | 2002-12-23 | 2004-07-15 | Vical Incorporated | Codon-optimized polynucleotide-based vaccines against human cytomegalovirus infection |
| US7491490B2 (en) * | 2004-05-12 | 2009-02-17 | Wisconsin Alumni Research Foundation | Cytomegalovirus disintegrin-like peptides |
| EP1994151A2 (en) * | 2006-03-08 | 2008-11-26 | University of Rochester | Compositions and methods for detection and treatment of human herpesvirus (hhv)-6 |
| CN101780277A (zh) * | 2009-01-15 | 2010-07-21 | 鑫品生医科技股份有限公司 | 含衍生自细胞巨大病毒的免疫原组成物及其使用方法 |
| SG189176A1 (en) * | 2010-10-15 | 2013-05-31 | Glaxosmithkline Biolog Sa | Cytomegalovirus gb antigen |
-
2010
- 2010-10-29 US US13/505,099 patent/US8802106B2/en active Active
- 2010-10-29 CA CA2779459A patent/CA2779459A1/en not_active Abandoned
- 2010-10-29 JP JP2012537122A patent/JP2013509432A/ja active Pending
- 2010-10-29 AU AU2010313339A patent/AU2010313339B2/en not_active Ceased
- 2010-10-29 WO PCT/US2010/054743 patent/WO2011053798A2/en not_active Ceased
- 2010-10-29 EP EP10827534.8A patent/EP2493911B1/en not_active Not-in-force
-
2014
- 2014-07-09 US US14/327,287 patent/US9434769B2/en active Active
-
2016
- 2016-01-28 JP JP2016014209A patent/JP6209228B2/ja not_active Expired - Fee Related
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