AU2010313339B2 - Peptide compositions and methods for inhibiting herpesvirus infection - Google Patents
Peptide compositions and methods for inhibiting herpesvirus infection Download PDFInfo
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- AU2010313339B2 AU2010313339B2 AU2010313339A AU2010313339A AU2010313339B2 AU 2010313339 B2 AU2010313339 B2 AU 2010313339B2 AU 2010313339 A AU2010313339 A AU 2010313339A AU 2010313339 A AU2010313339 A AU 2010313339A AU 2010313339 B2 AU2010313339 B2 AU 2010313339B2
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/245—Herpetoviridae, e.g. herpes simplex virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
- C07K14/01—DNA viruses
- C07K14/03—Herpetoviridae, e.g. pseudorabies virus
- C07K14/04—Varicella-zoster virus
- C07K14/045—Cytomegalovirus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16111—Cytomegalovirus, e.g. human herpesvirus 5
- C12N2710/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16111—Cytomegalovirus, e.g. human herpesvirus 5
- C12N2710/16133—Use of viral protein as therapeutic agent other than vaccine, e.g. apoptosis inducing or anti-inflammatory
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Virology (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Tropical Medicine & Parasitology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Biotechnology (AREA)
- Engineering & Computer Science (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US28011209P | 2009-10-30 | 2009-10-30 | |
| US61/280,112 | 2009-10-30 | ||
| PCT/US2010/054743 WO2011053798A2 (en) | 2009-10-30 | 2010-10-29 | Peptide compositions and methods for inhibiting herpesvirus infection |
Publications (2)
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| AU2010313339A1 AU2010313339A1 (en) | 2012-06-07 |
| AU2010313339B2 true AU2010313339B2 (en) | 2016-05-26 |
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| AU2010313339A Ceased AU2010313339B2 (en) | 2009-10-30 | 2010-10-29 | Peptide compositions and methods for inhibiting herpesvirus infection |
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|---|---|
| US (2) | US8802106B2 (https=) |
| EP (1) | EP2493911B1 (https=) |
| JP (2) | JP2013509432A (https=) |
| AU (1) | AU2010313339B2 (https=) |
| CA (1) | CA2779459A1 (https=) |
| WO (1) | WO2011053798A2 (https=) |
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| SG189176A1 (en) * | 2010-10-15 | 2013-05-31 | Glaxosmithkline Biolog Sa | Cytomegalovirus gb antigen |
| GB201312133D0 (en) * | 2013-07-05 | 2013-08-21 | Univ Birmingham | Immunotherapy |
| AU2014362234B2 (en) * | 2013-12-11 | 2019-09-12 | The Henry M. Jackson Foundation For The Advancement Of Military Medicine, Inc. | Human herpesvirus trimeric glycoprotein B, protein complexes comprising trimeric gB and their use as vaccines |
| US10611800B2 (en) | 2016-03-11 | 2020-04-07 | Pfizer Inc. | Human cytomegalovirus gB polypeptide |
| US11390661B2 (en) | 2016-06-27 | 2022-07-19 | Aicuris Anti-Infective Cures Gmbh | HCMV entry inhibitors |
| US11629172B2 (en) | 2018-12-21 | 2023-04-18 | Pfizer Inc. | Human cytomegalovirus gB polypeptide |
| CN111675752B (zh) * | 2020-03-16 | 2023-07-07 | 成都奥达生物科技有限公司 | 一种冠状病毒膜融合抑制剂及其药物用途 |
| TWI810589B (zh) | 2020-06-21 | 2023-08-01 | 美商輝瑞股份有限公司 | 人巨細胞病毒糖蛋白Ｂ（ｇＢ）多肽 |
| JP2024508799A (ja) * | 2021-02-24 | 2024-02-28 | ファイザー・インク | ヒトサイトメガロウイルス糖タンパク質ｂポリペプチドにおける新規創薬可能領域およびその使用方法 |
| CN115894708B (zh) * | 2022-08-16 | 2023-10-10 | 青岛大学 | 一种人巨细胞病毒抗原表位嵌合肽及其应用 |
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| WO2003000720A1 (en) * | 2001-06-26 | 2003-01-03 | The Council Of The Queensland Institute Of Medical Research | Novel human cytomegalovirus (hcmv) cytotoxic t cell epitopes, polyepitopes, compositions comprising same and diagnostic and prophylactic and therapeutic uses therefor |
| US20050260199A1 (en) * | 2004-05-12 | 2005-11-24 | Teresa Compton | Cytomegalovirus disintegrin-like peptides |
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| CA1335429C (en) * | 1986-03-07 | 1995-05-02 | Geoffrey L. Smith | Processes for the production of hcmv glycoproteins, antibodies thereto and hcmv vaccines, and recombinant vectors therefor |
| JP2607712B2 (ja) * | 1988-01-29 | 1997-05-07 | カイロン コーポレイション | 組換えｃｍｖ中和タンパク |
| US5514577A (en) * | 1990-02-26 | 1996-05-07 | Isis Pharmaceuticals, Inc. | Oligonucleotide therapies for modulating the effects of herpes viruses |
| US5633230A (en) * | 1990-10-24 | 1997-05-27 | Allelix Biopharmaceuticals, Inc. | Treatment of cytomegalovirus infection |
| US5831001A (en) * | 1990-10-24 | 1998-11-03 | Allelix Biopharmaceuticals Inc. | Treatment of herpesvirus infection |
| US5464933A (en) | 1993-06-07 | 1995-11-07 | Duke University | Synthetic peptide inhibitors of HIV transmission |
| GB9409962D0 (en) * | 1994-05-18 | 1994-07-06 | Smithkline Beecham Biolog | Novel compounds |
| CA2295933A1 (en) * | 1997-07-03 | 1999-01-14 | Smithkline Beecham Corporation | Compounds and methods for treating and screening viral reactivation |
| US20030036181A1 (en) * | 2000-06-30 | 2003-02-20 | Okkels Jens Sigurd | Peptide extended glycosylated polypeptides |
| FR2818279B1 (fr) * | 2000-12-15 | 2005-02-25 | Univ Paris Curie | Peptide de la glycoproteine b de l'herpesvirus humain 7 utilisable notamment dans un test serologique elisa |
| WO2004058166A2 (en) * | 2002-12-23 | 2004-07-15 | Vical Incorporated | Codon-optimized polynucleotide-based vaccines against human cytomegalovirus infection |
| EP1994151A2 (en) * | 2006-03-08 | 2008-11-26 | University of Rochester | Compositions and methods for detection and treatment of human herpesvirus (hhv)-6 |
| CN101780277A (zh) * | 2009-01-15 | 2010-07-21 | 鑫品生医科技股份有限公司 | 含衍生自细胞巨大病毒的免疫原组成物及其使用方法 |
| SG189176A1 (en) * | 2010-10-15 | 2013-05-31 | Glaxosmithkline Biolog Sa | Cytomegalovirus gb antigen |
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2010
- 2010-10-29 US US13/505,099 patent/US8802106B2/en active Active
- 2010-10-29 CA CA2779459A patent/CA2779459A1/en not_active Abandoned
- 2010-10-29 JP JP2012537122A patent/JP2013509432A/ja active Pending
- 2010-10-29 AU AU2010313339A patent/AU2010313339B2/en not_active Ceased
- 2010-10-29 WO PCT/US2010/054743 patent/WO2011053798A2/en not_active Ceased
- 2010-10-29 EP EP10827534.8A patent/EP2493911B1/en not_active Not-in-force
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2014
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- 2016-01-28 JP JP2016014209A patent/JP6209228B2/ja not_active Expired - Fee Related
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2003000720A1 (en) * | 2001-06-26 | 2003-01-03 | The Council Of The Queensland Institute Of Medical Research | Novel human cytomegalovirus (hcmv) cytotoxic t cell epitopes, polyepitopes, compositions comprising same and diagnostic and prophylactic and therapeutic uses therefor |
| US20050260199A1 (en) * | 2004-05-12 | 2005-11-24 | Teresa Compton | Cytomegalovirus disintegrin-like peptides |
Non-Patent Citations (1)
| Title |
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| UniProt accession Q9WMX1, 1 November 1999 * |
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|---|---|
| JP2016128477A (ja) | 2016-07-14 |
| EP2493911A4 (en) | 2014-01-01 |
| EP2493911A2 (en) | 2012-09-05 |
| WO2011053798A2 (en) | 2011-05-05 |
| US8802106B2 (en) | 2014-08-12 |
| US20130005648A1 (en) | 2013-01-03 |
| EP2493911B1 (en) | 2017-10-18 |
| AU2010313339A1 (en) | 2012-06-07 |
| US20150119318A1 (en) | 2015-04-30 |
| JP2013509432A (ja) | 2013-03-14 |
| WO2011053798A3 (en) | 2011-09-22 |
| US9434769B2 (en) | 2016-09-06 |
| CA2779459A1 (en) | 2011-05-05 |
| JP6209228B2 (ja) | 2017-10-04 |
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