JP2013507922A5 - - Google Patents
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- Publication number
- JP2013507922A5 JP2013507922A5 JP2012534269A JP2012534269A JP2013507922A5 JP 2013507922 A5 JP2013507922 A5 JP 2013507922A5 JP 2012534269 A JP2012534269 A JP 2012534269A JP 2012534269 A JP2012534269 A JP 2012534269A JP 2013507922 A5 JP2013507922 A5 JP 2013507922A5
- Authority
- JP
- Japan
- Prior art keywords
- cell
- cell culture
- trough
- micrometers
- chamber
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 238000004113 cell culture Methods 0.000 claims description 22
- 230000010412 perfusion Effects 0.000 claims description 16
- 239000012530 fluid Substances 0.000 claims description 6
- 239000006143 cell culture medium Substances 0.000 claims description 3
- 210000004027 cell Anatomy 0.000 claims 16
- 210000004748 cultured cell Anatomy 0.000 claims 1
- 230000002262 irrigation Effects 0.000 claims 1
- 238000003973 irrigation Methods 0.000 claims 1
- 230000014759 maintenance of location Effects 0.000 description 2
- 238000000034 method Methods 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US25075409P | 2009-10-12 | 2009-10-12 | |
| US61/250,754 | 2009-10-12 | ||
| PCT/US2010/052212 WO2011046884A2 (en) | 2009-10-12 | 2010-10-12 | Microfluidic device for cell culture |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2013507922A JP2013507922A (ja) | 2013-03-07 |
| JP2013507922A5 true JP2013507922A5 (enExample) | 2013-05-30 |
Family
ID=43855151
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012534269A Abandoned JP2013507922A (ja) | 2009-10-12 | 2010-10-12 | 細胞培養用マイクロ流体デバイス |
Country Status (5)
| Country | Link |
|---|---|
| US (2) | US8481303B2 (enExample) |
| EP (1) | EP2488628A2 (enExample) |
| JP (1) | JP2013507922A (enExample) |
| CN (1) | CN102612554A (enExample) |
| WO (1) | WO2011046884A2 (enExample) |
Families Citing this family (57)
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| US7534601B2 (en) * | 2002-08-27 | 2009-05-19 | Vanderbilt University | Capillary perfused bioreactors with multiple chambers |
| JP2012509663A (ja) * | 2008-11-21 | 2012-04-26 | コーニング インコーポレイテッド | 細胞培養のための、突起間隔を開けた基板および装置 |
| AU2010319881A1 (en) * | 2009-10-29 | 2012-05-03 | The Charles Stark Draper Laboratory, Inc. | Microfluidic device for blood dialysis |
| US9522396B2 (en) | 2010-12-29 | 2016-12-20 | S.D. Sight Diagnostics Ltd. | Apparatus and method for automatic detection of pathogens |
| CN102234614B (zh) * | 2011-05-30 | 2013-02-13 | 中国科学院苏州纳米技术与纳米仿生研究所 | 微流控细胞悬浮培养芯片及其应用 |
| EP2714892B1 (en) | 2011-06-02 | 2018-02-21 | President and Fellows of Harvard College | Methods and uses for ex vivo tissue culture systems |
| CA2839435C (en) * | 2011-06-15 | 2021-05-11 | The Charles Stark Draper Laboratory, Inc. | Systems, methods, and devices relating to a biomimetic cellularized nephron unit |
| JP2014516582A (ja) * | 2011-06-15 | 2014-07-17 | ザ チャールズ スターク ドレイパー ラボラトリー インク | 生体模倣環境において細胞を培養するためのデバイスおよび方法 |
| WO2013098821A1 (en) | 2011-12-29 | 2013-07-04 | Parasight Ltd. | Methods and systems for detecting a pathogen in a biological sample |
| WO2014031523A2 (en) * | 2012-08-19 | 2014-02-27 | University Of Rochester | Method for preparing microfluidic device with reduced channel height |
| US20140127733A1 (en) * | 2012-11-01 | 2014-05-08 | Moffit Cancer Center | Ex vivo microfluidic analysis of biologic samples |
| EP2972313B1 (en) | 2013-03-15 | 2018-01-03 | Rinker, Kristina, D. | Ported parallel plate flow chamber and methods for use thereof |
| EP3869257B1 (en) | 2013-05-23 | 2024-05-08 | S.D. Sight Diagnostics Ltd. | Method and system for imaging a cell sample |
| IL227276A0 (en) | 2013-07-01 | 2014-03-06 | Parasight Ltd | A method and system for preparing a monolayer of cells, particularly suitable for diagnosis |
| EP3024921B1 (en) | 2013-07-22 | 2025-12-10 | The Regents of The University of California | Microfluidics cell culture device |
| EP3955042B1 (en) | 2013-08-26 | 2024-08-21 | S.D. Sight Diagnostics Ltd. | Digital microscopy systems, methods and computer program products |
| US20150064689A1 (en) * | 2013-08-29 | 2015-03-05 | The Charles Stark Draper Laboratory, Inc. | System and method for analyzing transmissibility of influenza |
| CN103627635B (zh) * | 2013-11-18 | 2015-05-20 | 辽宁中医药大学 | 一种用于细胞迁移和侵袭实验的多功能微流控芯片 |
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| US9631167B2 (en) | 2014-03-21 | 2017-04-25 | Iontox, Llc | Dynamic multi organ plate |
| EP3177709B1 (en) * | 2014-08-07 | 2022-05-18 | The J. David Gladstone Institutes, A Testamentary Trust Established under The Will of J. David Gladstone | Reversible stencils for fabricating micro-tissues |
| US10482595B2 (en) | 2014-08-27 | 2019-11-19 | S.D. Sight Diagnostics Ltd. | System and method for calculating focus variation for a digital microscope |
| CN104293666B (zh) * | 2014-09-11 | 2016-06-22 | 大连理工大学 | 两种不同单细胞之间相互作用的微流控芯片装置 |
| CN105713835B (zh) * | 2014-12-05 | 2018-11-09 | 中国科学院大连化学物理研究所 | 一种基于微流控芯片的多功能区域细胞三维共培养方法 |
| US10279345B2 (en) | 2014-12-12 | 2019-05-07 | Opko Diagnostics, Llc | Fluidic systems comprising an incubation channel, including fluidic systems formed by molding |
| AU2016250689B2 (en) | 2015-04-22 | 2021-07-08 | Berkeley Lights, Inc. | Microfluidic cell culture |
| GB201512600D0 (en) * | 2015-07-17 | 2015-08-26 | Koniku Ltd | Cell culture, transport and investigation |
| AU2016322966B2 (en) | 2015-09-17 | 2021-10-14 | S.D. Sight Diagnostics Ltd | Methods and apparatus for detecting an entity in a bodily sample |
| US10799865B2 (en) | 2015-10-27 | 2020-10-13 | Berkeley Lights, Inc. | Microfluidic apparatus having an optimized electrowetting surface and related systems and methods |
| WO2017096297A1 (en) | 2015-12-04 | 2017-06-08 | EMULATE, Inc. | Open-top microfluidic device with structural anchors |
| EP3416591B1 (en) * | 2016-02-16 | 2021-10-27 | Koninklijke Philips N.V. | Surface topographies for altering the physiology of living cells |
| EP3436035B1 (en) * | 2016-03-29 | 2024-09-04 | SmsBiotech, Inc. | Compositions and methods for using small mobile stem cells |
| WO2017168411A1 (en) | 2016-03-30 | 2017-10-05 | S.D. Sight Diagnostics Ltd | Image processing device for identifying blood parasites |
| WO2017184595A1 (en) * | 2016-04-18 | 2017-10-26 | Saint Louis University | Integration of three-dimensional cell culture scaffolds in microfluidic devices by direct fiber spinning |
| US11307196B2 (en) | 2016-05-11 | 2022-04-19 | S.D. Sight Diagnostics Ltd. | Sample carrier for optical measurements |
| CN109564209B (zh) | 2016-05-11 | 2022-05-31 | 思迪赛特诊断有限公司 | 对样品实施的光学测量 |
| AU2017271673B2 (en) | 2016-05-26 | 2022-04-14 | Berkeley Lights, Inc. | Covalently modified surfaces, kits, and methods of preparation and use |
| CN105838606B (zh) * | 2016-06-08 | 2018-10-02 | 牛海涛 | 一种高通量细胞联合培养芯片 |
| US10243097B2 (en) * | 2016-09-09 | 2019-03-26 | eLux Inc. | Fluidic assembly using tunable suspension flow |
| WO2018080308A2 (en) * | 2016-10-28 | 2018-05-03 | Materiomics B.V. | Surface topographies for stimulating endothelialization |
| WO2018208332A2 (en) | 2017-02-17 | 2018-11-15 | Koniku, Inc. | Systems for detection |
| US11572590B2 (en) | 2017-03-31 | 2023-02-07 | Dana-Farber Cancer Institute, Inc. | Methods for evaluating tumor cell spheroids using 3D microfluidic cell culture device |
| WO2018187181A1 (en) | 2017-04-03 | 2018-10-11 | The Charles Stark Draper Laboratory, Inc. | Microfluidic system for evaluation of chemotherapeutic and immunotherapeutic drugs |
| EP3710810B1 (en) | 2017-11-14 | 2023-09-06 | S.D. Sight Diagnostics Ltd. | Sample carrier for optical measurements |
| KR101979145B1 (ko) * | 2018-01-30 | 2019-05-15 | 서강대학교산학협력단 | 신경줄기세포 배양용 미세유체칩 및 이의 용도 |
| WO2020081288A1 (en) * | 2018-10-14 | 2020-04-23 | Arizona Board Of Regents On Behalf Of Arizona State University | Microfluidic devices and methods incorporating organized three-dimensional tissue constructs |
| KR102170851B1 (ko) * | 2018-11-13 | 2020-10-27 | 엠비디 주식회사 | 세포 배양 플레이트 |
| CN113825831B (zh) * | 2019-05-13 | 2024-09-17 | 纽索思创新有限公司 | 用于细胞培养的微流控装置和方法 |
| JP7677972B2 (ja) | 2019-12-12 | 2025-05-15 | エス．ディー．サイト ダイアグノスティックス リミテッド | カラー血液スミア画像の人工的な生成 |
| AU2020400401A1 (en) | 2019-12-12 | 2022-06-02 | S.D. Sight Diagnostics Ltd | Analyzing an analyte disposed within a medium |
| CN111068516B (zh) * | 2020-01-18 | 2023-11-14 | 浙江大学 | 多元强化耦合智能调控防止高粘性灰在催化剂表面沉积的系统及方法 |
| JP7421763B2 (ja) * | 2020-12-02 | 2024-01-25 | ウシオ電機株式会社 | 培養容器及び培養容器の使用方法 |
| WO2022159097A1 (en) * | 2021-01-22 | 2022-07-28 | Hewlett-Packard Development Company, L.P. | Microfluidic device chamber pillars |
| EP4363606A4 (en) * | 2021-06-30 | 2024-08-21 | Hewlett-Packard Development Company, L.P. | CHAMBER COLUMNS OF A MICROFLUIDIC DEVICE |
| CN114453039B (zh) * | 2022-02-08 | 2025-09-30 | 浙江扬清芯片技术有限公司 | 一种离心式微流控芯片点阵阀结构 |
| US12186748B2 (en) | 2022-06-24 | 2025-01-07 | Hewlett-Packard Development Company, L.P. | Self-priming microfluidic structures |
| CN115742293A (zh) * | 2022-11-01 | 2023-03-07 | 福建星海通信科技有限公司 | 一种基于dlp3d打印的生物应用微流体器件制备方法 |
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| GB1437404A (en) | 1973-09-24 | 1976-05-26 | Kaye S | Method and means for assaying biological factors demonstrating quantal response |
| EP0075973B1 (de) | 1981-09-18 | 1987-01-21 | BBC Brown Boveri AG | Gleichdruckluftspeicherkaverne mit hydraulischem Druckausgleich für Luftspeichergasturbinenkraftwerke |
| DE4116727C2 (de) | 1991-05-17 | 1995-09-07 | Uwe Dr Marx | Verfahren und Vorrichtung zur gleichzeitigen Kultivierung unterschiedlicher Säugerzellen |
| DE4132379A1 (de) | 1991-09-28 | 1993-04-08 | Kernforschungsz Karlsruhe | Substrat fuer zellkulturen und kultur von zellen oder zellaggregaten |
| DE69433550T2 (de) | 1993-11-02 | 2009-09-10 | Bio-Lok International, Inc., Deerfield Beach | Zellenwuchskontrolle |
| FR2741357B1 (fr) | 1995-11-22 | 1998-01-16 | Corning Inc | Procede de fabrication d'une plaquette de support d'un reseau bidimensionnel de micropuits, notamment pour essais ou cultures biologiques |
| US6391578B2 (en) | 1997-04-09 | 2002-05-21 | 3M Innovative Properties Company | Method and devices for partitioning biological sample liquids into microvolumes |
| CH692583A5 (de) | 1998-03-03 | 2002-08-15 | Weidmann H Ag | Kulturgefäss. |
| GB9805214D0 (en) | 1998-03-11 | 1998-05-06 | Univ Glasgow | Cell adhesion |
| ATE227338T1 (de) | 1998-03-18 | 2002-11-15 | Massachusetts Inst Technology | Vaskularisierte perfundierte anordnungen für mikrogewebe und mikroorgane |
| JP2000231007A (ja) | 1999-02-09 | 2000-08-22 | Ricoh Opt Ind Co Ltd | 凹型微細形状のアレイ状パターン形成方法及びその形成方法を用いて製作される平板型レンズアレイ及び液晶表示素子及び平板型オイルトラップ |
| US7033821B2 (en) | 2000-11-08 | 2006-04-25 | Surface Logix, Inc. | Device for monitoring cell motility in real-time |
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| US6653124B1 (en) | 2000-11-10 | 2003-11-25 | Cytoplex Biosciences Inc. | Array-based microenvironment for cell culturing, cell monitoring and drug-target validation |
| US7018418B2 (en) | 2001-01-25 | 2006-03-28 | Tecomet, Inc. | Textured surface having undercut micro recesses in a surface |
| US7288405B2 (en) | 2001-04-25 | 2007-10-30 | Cornell Research Foundation, Inc. | Devices and methods for pharmacokinetic-based cell culture system |
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| US20030064000A1 (en) | 2001-09-24 | 2003-04-03 | Wilson Burgess | Methods of sterilizing biological mixtures using stabilizer mixtures |
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| US20040067585A1 (en) | 2002-10-07 | 2004-04-08 | Yu-Chi Wang | Cell cultivation surface and method of making the same |
| US7190449B2 (en) | 2002-10-28 | 2007-03-13 | Nanopoint, Inc. | Cell tray |
| DE60333715D1 (de) | 2002-10-30 | 2010-09-23 | Hitachi Ltd | Verfahren zur Herstellung funktioneller Substrate, die kolumnare Mikrosäulen aufweisen |
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| US7329537B2 (en) | 2003-04-17 | 2008-02-12 | Nexcelom Bioscience, Llc | Micro-pattern embedded plastic optical film device for cell-based assays |
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| EP1901067A3 (en) | 2004-08-03 | 2009-05-13 | On-Chip Cellomics Consortium | Cellomics system |
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| GB2427688A (en) | 2005-06-28 | 2007-01-03 | Inogen S A | Microwell plate |
| KR20110086160A (ko) | 2005-09-15 | 2011-07-27 | 스위트 파워 아이엔씨. | 플렉시블 기판 및 마이크로 필러 구조를 구비하는 미생물 연료전지 |
| US20070249044A1 (en) | 2006-01-30 | 2007-10-25 | University Of Illinois At Chicago | Microstructures in three dimensional gel suspensions for growth of cells |
| JP4506987B2 (ja) | 2006-07-21 | 2010-07-21 | 株式会社日立ハイテクノロジーズ | エネルギ線硬化型樹脂の転写方法、転写装置及びディスクまたは半導体デバイス |
| JP5013584B2 (ja) | 2006-08-30 | 2012-08-29 | 株式会社日立製作所 | 軟骨細胞の培養方法および軟骨細胞 |
-
2010
- 2010-03-03 US US12/716,680 patent/US8481303B2/en not_active Expired - Fee Related
- 2010-10-12 WO PCT/US2010/052212 patent/WO2011046884A2/en not_active Ceased
- 2010-10-12 EP EP10766202A patent/EP2488628A2/en not_active Withdrawn
- 2010-10-12 JP JP2012534269A patent/JP2013507922A/ja not_active Abandoned
- 2010-10-12 CN CN2010800468967A patent/CN102612554A/zh active Pending
-
2013
- 2013-06-06 US US13/911,490 patent/US8679843B2/en active Active
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