JP2013506843A5 - - Google Patents
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- JP2013506843A5 JP2013506843A5 JP2012532349A JP2012532349A JP2013506843A5 JP 2013506843 A5 JP2013506843 A5 JP 2013506843A5 JP 2012532349 A JP2012532349 A JP 2012532349A JP 2012532349 A JP2012532349 A JP 2012532349A JP 2013506843 A5 JP2013506843 A5 JP 2013506843A5
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- 239000002207 metabolite Substances 0.000 description 22
- 230000000875 corresponding effect Effects 0.000 description 21
- 238000002705 metabolomic analysis Methods 0.000 description 12
- 230000001431 metabolomic effect Effects 0.000 description 10
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Images
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US24804009P | 2009-10-02 | 2009-10-02 | |
| US61/248,040 | 2009-10-02 | ||
| US34728710P | 2010-05-21 | 2010-05-21 | |
| US61/347,287 | 2010-05-21 | ||
| PCT/US2010/051091 WO2011041656A2 (en) | 2009-10-02 | 2010-10-01 | Apparatus and associated method for analyzing small molecule components in a complex mixture |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013506843A JP2013506843A (ja) | 2013-02-28 |
| JP2013506843A5 true JP2013506843A5 (https=) | 2015-07-30 |
| JP5866287B2 JP5866287B2 (ja) | 2016-02-17 |
Family
ID=43416381
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012532349A Active JP5866287B2 (ja) | 2009-10-02 | 2010-10-01 | 複雑な混合物における小分子成分分析のための装置及び関連する方法 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US9189595B2 (https=) |
| EP (1) | EP2486504B1 (https=) |
| JP (1) | JP5866287B2 (https=) |
| CN (1) | CN102667789A (https=) |
| WO (1) | WO2011041656A2 (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3137891B1 (en) * | 2014-04-28 | 2024-01-17 | DH Technologies Development Pte. Ltd. | Multi-trace quantitation |
| JP6538083B2 (ja) * | 2014-05-30 | 2019-07-03 | メタボロン，インコーポレイテッド | 複数のサンプル処理における複雑な混合物の小分子成分を分析するための方法、並びに関連する装置及びコンピュータプログラム製品 |
| ES2982037T3 (es) | 2017-12-15 | 2024-10-14 | Metabolon Inc | Método para analizar componentes de moléculas pequeñas de una mezcla compleja, y aparato asociado y producto de programa informático |
Family Cites Families (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5162791A (ja) * | 1974-10-28 | 1976-05-31 | Takeda Riken Ind Co Ltd | Hakeimensekisekisansochi |
| US4315149A (en) * | 1980-05-23 | 1982-02-09 | The Board Of Regents Of The University Of Nebraska | Mass spectrometer |
| US4353242A (en) * | 1980-12-16 | 1982-10-12 | University Of Utah Research Foundation | Multichannel detection and resolution of chromatographic peaks |
| JP2605081B2 (ja) * | 1988-02-23 | 1997-04-30 | 株式会社島津製作所 | 組成比定量装置 |
| JPH0210264A (ja) * | 1988-06-29 | 1990-01-16 | Shimadzu Corp | クロマトグラフ用データ処理装置 |
| US5300771A (en) * | 1992-06-02 | 1994-04-05 | Analytica Of Branford | Method for determining the molecular weights of polyatomic molecules by mass analysis of their multiply charged ions |
| JP2904061B2 (ja) * | 1995-06-07 | 1999-06-14 | 株式会社島津製作所 | 液体クロマトグラフ質量分析装置 |
| US20030017483A1 (en) * | 1998-05-12 | 2003-01-23 | Ecker David J. | Modulation of molecular interaction sites on RNA and other biomolecules |
| US6969763B1 (en) * | 1999-05-12 | 2005-11-29 | Isis Pharmaceuticals, Inc. | Molecular interaction sites of interleukin-2 RNA and methods of modulating the same |
| US20020009740A1 (en) | 2000-04-14 | 2002-01-24 | Rima Kaddurah-Daouk | Methods for drug discovery, disease treatment, and diagnosis using metabolomics |
| US7329489B2 (en) | 2000-04-14 | 2008-02-12 | Matabolon, Inc. | Methods for drug discovery, disease treatment, and diagnosis using metabolomics |
| WO2002021099A2 (en) * | 2000-09-08 | 2002-03-14 | Waters Investments Limited | Method and apparatus for determining the boundaries of a detector response profile and for controlling processes |
| US20020086434A1 (en) * | 2000-12-14 | 2002-07-04 | Roussis Stilianos G. | Direct determination of acid distributions crudes and crude fractions |
| US6787760B2 (en) * | 2001-10-12 | 2004-09-07 | Battelle Memorial Institute | Method for increasing the dynamic range of mass spectrometers |
| GB2405972B (en) * | 2002-05-31 | 2007-08-15 | Waters Investments Ltd | A method of using data binning in the analysis of chromatograhpy/spectrometry data |
| US7510880B2 (en) * | 2002-06-26 | 2009-03-31 | Gross Richard W | Multidimensional mass spectrometry of serum and cellular lipids directly from biologic extracts |
| US7170052B2 (en) * | 2003-12-31 | 2007-01-30 | Ionwerks, Inc. | MALDI-IM-ortho-TOF mass spectrometry with simultaneous positive and negative mode detection |
| CA2585453C (en) * | 2004-10-28 | 2020-02-18 | Cerno Bioscience Llc | Qualitative and quantitative mass spectral analysis |
| WO2007019485A1 (en) | 2005-08-08 | 2007-02-15 | Metabolon Inc. | A system, method, and computer program product using a database in a computing system to compile and compare metabolomic data obtained from a plurality of samples |
| US7949475B2 (en) | 2005-08-08 | 2011-05-24 | Metabolon Inc. | System and method for analyzing metabolomic data |
| US20070265216A1 (en) * | 2005-10-05 | 2007-11-15 | Gross Richard W | Enhanced medical treatment in diabetic cardiomyopathy |
| CA2646890C (en) | 2006-03-21 | 2012-07-31 | Metabolon, Inc. | A system, method, and computer program product for analyzing spectrometry data to indentify and quantify individual components in a sample |
| EP2024064B1 (en) * | 2006-05-26 | 2014-11-19 | Waters Technologies Corporation | Ion detection and parameter estimation for liquid chromatography - ion mobility spectrometry - mass spectrometry data |
| JP5068498B2 (ja) * | 2006-08-31 | 2012-11-07 | 株式会社日立ハイテクノロジーズ | クロマトグラフ分析装置 |
| JP5170650B2 (ja) * | 2008-02-29 | 2013-03-27 | 株式会社リガク | ガス定量分析方法及びガス定量分析装置 |
| JP5166932B2 (ja) * | 2008-03-21 | 2013-03-21 | 日本電子株式会社 | クロマトグラフ質量分析装置 |
| CA2724422A1 (en) * | 2008-05-28 | 2009-12-23 | Basf Se | Means and methods for assessing increased peroxisomal proliferation |
| CN102074448B (zh) * | 2009-11-20 | 2014-09-24 | 同方威视技术股份有限公司 | 离子迁移谱仪以及提高其检测灵敏度的方法 |
| WO2011155984A1 (en) * | 2010-06-11 | 2011-12-15 | Waters Technologies Corporation | Techniques for mass spectrometry peak list computation using parallel processing |
-
2010
- 2010-10-01 CN CN201080054995XA patent/CN102667789A/zh active Pending
- 2010-10-01 WO PCT/US2010/051091 patent/WO2011041656A2/en not_active Ceased
- 2010-10-01 EP EP10774032.6A patent/EP2486504B1/en active Active
- 2010-10-01 JP JP2012532349A patent/JP5866287B2/ja active Active
-
2012
- 2012-03-27 US US13/431,126 patent/US9189595B2/en active Active
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