JP2013504623A5 - - Google Patents
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- JP2013504623A5 JP2013504623A5 JP2012529823A JP2012529823A JP2013504623A5 JP 2013504623 A5 JP2013504623 A5 JP 2013504623A5 JP 2012529823 A JP2012529823 A JP 2012529823A JP 2012529823 A JP2012529823 A JP 2012529823A JP 2013504623 A5 JP2013504623 A5 JP 2013504623A5
- Authority
- JP
- Japan
- Prior art keywords
- yeast
- based immunotherapy
- agent
- subject
- combination
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Links
- 240000004808 Saccharomyces cerevisiae Species 0.000 claims 38
- 235000014680 Saccharomyces cerevisiae Nutrition 0.000 claims 38
- 238000009169 immunotherapy Methods 0.000 claims 20
- 239000003795 chemical substances by application Substances 0.000 claims 15
- 210000001744 T-lymphocyte Anatomy 0.000 claims 11
- 201000010099 disease Diseases 0.000 claims 8
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 8
- 239000000427 antigen Substances 0.000 claims 7
- 108091007433 antigens Proteins 0.000 claims 7
- 102000036639 antigens Human genes 0.000 claims 7
- 210000000612 antigen-presenting cell Anatomy 0.000 claims 6
- 230000024949 interleukin-17 production Effects 0.000 claims 5
- 238000000034 method Methods 0.000 claims 5
- 108020003175 receptors Proteins 0.000 claims 5
- 102000005962 receptors Human genes 0.000 claims 5
- 230000004044 response Effects 0.000 claims 5
- 102000013691 Interleukin-17 Human genes 0.000 claims 4
- 102000004889 Interleukin-6 Human genes 0.000 claims 4
- 108090001005 Interleukin-6 Proteins 0.000 claims 4
- 210000004027 cell Anatomy 0.000 claims 4
- 230000000694 effects Effects 0.000 claims 4
- 229940100601 interleukin-6 Drugs 0.000 claims 4
- 108010002352 Interleukin-1 Proteins 0.000 claims 3
- 230000001024 immunotherapeutic effect Effects 0.000 claims 3
- 102000002227 Interferon Type I Human genes 0.000 claims 2
- 108010014726 Interferon Type I Proteins 0.000 claims 2
- 230000002708 enhancing effect Effects 0.000 claims 2
- 230000003612 virological effect Effects 0.000 claims 2
- 108091023037 Aptamer Proteins 0.000 claims 1
- 102000004127 Cytokines Human genes 0.000 claims 1
- 108090000695 Cytokines Proteins 0.000 claims 1
- 206010028980 Neoplasm Diseases 0.000 claims 1
- 102000016978 Orphan receptors Human genes 0.000 claims 1
- 108070000031 Orphan receptors Proteins 0.000 claims 1
- 108091008778 RORγ2 Proteins 0.000 claims 1
- 108020004459 Small interfering RNA Proteins 0.000 claims 1
- 230000006052 T cell proliferation Effects 0.000 claims 1
- 230000005867 T cell response Effects 0.000 claims 1
- 239000000556 agonist Substances 0.000 claims 1
- 201000011510 cancer Diseases 0.000 claims 1
- 208000002672 hepatitis B Diseases 0.000 claims 1
- 208000010710 hepatitis C virus infection Diseases 0.000 claims 1
- 230000028993 immune response Effects 0.000 claims 1
- 238000000338 in vitro Methods 0.000 claims 1
- 230000000977 initiatory effect Effects 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 108090000765 processed proteins & peptides Proteins 0.000 claims 1
- 102000004169 proteins and genes Human genes 0.000 claims 1
- 108090000623 proteins and genes Proteins 0.000 claims 1
- 230000004043 responsiveness Effects 0.000 claims 1
- 150000004492 retinoid derivatives Chemical class 0.000 claims 1
- 238000012216 screening Methods 0.000 claims 1
- 150000003384 small molecules Chemical class 0.000 claims 1
- 230000004083 survival effect Effects 0.000 claims 1
- 208000024891 symptom Diseases 0.000 claims 1
- 238000002560 therapeutic procedure Methods 0.000 claims 1
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US24235509P | 2009-09-14 | 2009-09-14 | |
| US24235309P | 2009-09-14 | 2009-09-14 | |
| US61/242,353 | 2009-09-14 | ||
| US61/242,355 | 2009-09-14 | ||
| US28856809P | 2009-12-21 | 2009-12-21 | |
| US61/288,568 | 2009-12-21 | ||
| PCT/US2010/048699 WO2011032119A1 (en) | 2009-09-14 | 2010-09-14 | Modulation of yeast-based immunotherapy products and responses |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013504623A JP2013504623A (ja) | 2013-02-07 |
| JP2013504623A5 true JP2013504623A5 (https=) | 2013-11-07 |
| JP5913103B2 JP5913103B2 (ja) | 2016-04-27 |
Family
ID=43034390
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012529823A Active JP5913103B2 (ja) | 2009-09-14 | 2010-09-14 | 酵母ベースの免疫療法組成物を含む組合せ物及び被験者のスクリーニング方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (3) | US8911722B2 (https=) |
| EP (1) | EP2477647B1 (https=) |
| JP (1) | JP5913103B2 (https=) |
| AU (1) | AU2010291985B2 (https=) |
| CA (1) | CA2774326C (https=) |
| WO (1) | WO2011032119A1 (https=) |
Families Citing this family (26)
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| AU2008214029B2 (en) | 2007-02-02 | 2014-01-30 | Globelmmune, Inc. | Methods for producing yeast-based vaccines |
| EP2134358A1 (en) | 2007-03-19 | 2009-12-23 | Globeimmune, Inc. | Compositions and methods for targeted ablation of mutational escape of targeted therapies for cancer |
| ES2725450T3 (es) | 2007-07-02 | 2019-09-24 | Etubics Corp | Métodos y composiciones para la producción de un vector adenoviral para su uso en vacunaciones múltiples |
| KR101781966B1 (ko) | 2009-04-17 | 2017-09-27 | 글로브이뮨 | 암에 대한 병용 면역요법 조성물 및 방법 |
| AU2010291985B2 (en) | 2009-09-14 | 2016-05-05 | The Regents Of The University Of Colorado | Modulation of yeast-based immunotherapy products and responses |
| US9254320B2 (en) | 2010-12-17 | 2016-02-09 | Globeimmune, Inc. | Compositions and methods for the treatment or prevention of human adenovirus-36 infection |
| EA028659B1 (ru) | 2011-02-12 | 2017-12-29 | Глоубиммьюн, Инк. | Терапевтическое средство на основе дрожжей для лечения хронического гепатита b |
| RU2690180C2 (ru) | 2011-03-17 | 2019-05-31 | Глоубиммьюн, Инк. | Иммунотерапевтические композиции на основе дрожжей с brachyury |
| BR112013032381B1 (pt) * | 2011-06-14 | 2021-01-12 | Globeimmune, Inc. | composições à base de levedura e métodos para o tratamento ou prevenção de infecção pelo vírus da hepatite delta |
| KR102049928B1 (ko) | 2011-08-17 | 2019-11-28 | 글로브이뮨 | 효모-muc1 면역요법 조성물 및 그 용도 |
| DE102011121069A1 (de) | 2011-12-13 | 2013-06-13 | Martin-Luther-Universität Halle-Wittenberg | Vakzinierung mittels rekombinanter Hefe durch Erzeugung einer protektiven humoralen Immunantwort gegen definierte Antigene |
| SG11201408652SA (en) | 2012-06-26 | 2015-01-29 | Biodesix Inc | Mass-spectral method for selection, and de-selection, of cancer patients for treatment with immune response generating therapies |
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| EP2929351B1 (en) * | 2012-12-10 | 2019-10-09 | The University of Queensland | Cell-free biofragment compositions and related systems, devices, and methods |
| MX374829B (es) | 2013-03-19 | 2025-03-06 | Globeimmune Inc | Composición a base de levadura para usarse para tratar cordoma. |
| US9782473B2 (en) | 2013-03-26 | 2017-10-10 | Globeimmune, Inc. | Compositions and methods for the treatment or prevention of human immunodeficiency virus infection |
| US10226522B2 (en) | 2013-08-30 | 2019-03-12 | Globeimmune, Inc. | Compositions and methods for the treatment or prevention of tuberculosis |
| US10799567B2 (en) * | 2014-04-11 | 2020-10-13 | Globeimmune, Inc. | Yeast-based immunotherapy and type I interferon sensitivity |
| KR102193635B1 (ko) | 2015-01-09 | 2020-12-21 | 이투빅스 코포레이션 | 복합 면역요법을 위한 방법 및 조성물 |
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| WO2016199904A1 (ja) * | 2015-06-10 | 2016-12-15 | 国立大学法人東京大学 | ワクチン用アジュバント、ワクチン、及び免疫誘導方法 |
| WO2017023840A1 (en) | 2015-08-03 | 2017-02-09 | Globeimmune, Inc. | Modified yeast-brachyury immunotherapeutic compositions |
| WO2017044979A2 (en) * | 2015-09-11 | 2017-03-16 | Ventria Bioscience Inc. | Lactoferrin compositions and methods for modulation of t cell subtypes and treatment of autoimmune diseases |
| WO2019222073A1 (en) | 2018-05-15 | 2019-11-21 | Globeimmune, Inc. | Lysates of recombinant yeast for inducing cellular immune responses |
| JP7721507B2 (ja) * | 2019-08-26 | 2025-08-12 | ザ ブリガム アンド ウィメンズ ホスピタル インコーポレイテッド | 操作された治療用微生物および関連受容体についての組成物および使用 |
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| KR101781966B1 (ko) | 2009-04-17 | 2017-09-27 | 글로브이뮨 | 암에 대한 병용 면역요법 조성물 및 방법 |
| AU2010291985B2 (en) | 2009-09-14 | 2016-05-05 | The Regents Of The University Of Colorado | Modulation of yeast-based immunotherapy products and responses |
| US20130121964A1 (en) | 2010-03-14 | 2013-05-16 | Globeimmune, Inc. | Pharmacogenomic and Response-Guided Treatment of Infectious Disease Using Yeast-Based Immunotherapy |
| WO2012019127A2 (en) | 2010-08-05 | 2012-02-09 | The Regents Of The University Of Colorado | Combination yeast-based immunotherapy and arginine therapy for the treatment of myeloid-derived supressor cell-associated diseases |
| US9254320B2 (en) | 2010-12-17 | 2016-02-09 | Globeimmune, Inc. | Compositions and methods for the treatment or prevention of human adenovirus-36 infection |
-
2010
- 2010-09-14 AU AU2010291985A patent/AU2010291985B2/en active Active
- 2010-09-14 US US13/395,965 patent/US8911722B2/en active Active
- 2010-09-14 EP EP10755290.3A patent/EP2477647B1/en active Active
- 2010-09-14 JP JP2012529823A patent/JP5913103B2/ja active Active
- 2010-09-14 WO PCT/US2010/048699 patent/WO2011032119A1/en not_active Ceased
- 2010-09-14 CA CA2774326A patent/CA2774326C/en active Active
-
2014
- 2014-11-10 US US14/536,903 patent/US10117915B2/en active Active
-
2018
- 2018-09-27 US US16/143,710 patent/US20190022197A1/en not_active Abandoned
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