JP2013504318A5 - - Google Patents
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- Publication number
- JP2013504318A5 JP2013504318A5 JP2012528465A JP2012528465A JP2013504318A5 JP 2013504318 A5 JP2013504318 A5 JP 2013504318A5 JP 2012528465 A JP2012528465 A JP 2012528465A JP 2012528465 A JP2012528465 A JP 2012528465A JP 2013504318 A5 JP2013504318 A5 JP 2013504318A5
- Authority
- JP
- Japan
- Prior art keywords
- pain
- peptide
- isolated
- making
- subject
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 108090000765 processed proteins & peptides Proteins 0.000 claims 20
- 208000002193 Pain Diseases 0.000 claims 15
- 238000000034 method Methods 0.000 claims 8
- 230000001684 chronic effect Effects 0.000 claims 3
- 208000019695 Migraine disease Diseases 0.000 claims 2
- 206010028980 Neoplasm Diseases 0.000 claims 2
- 206010036376 Postherpetic Neuralgia Diseases 0.000 claims 2
- 201000011510 cancer Diseases 0.000 claims 2
- RWSXRVCMGQZWBV-WDSKDSINSA-N glutathione Chemical compound OC(=O)[C@@H](N)CCC(=O)N[C@@H](CS)C(=O)NCC(O)=O RWSXRVCMGQZWBV-WDSKDSINSA-N 0.000 claims 2
- 206010027599 migraine Diseases 0.000 claims 2
- 208000004296 neuralgia Diseases 0.000 claims 2
- 239000008194 pharmaceutical composition Substances 0.000 claims 2
- 239000002708 spider venom Substances 0.000 claims 2
- 206010044652 trigeminal neuralgia Diseases 0.000 claims 2
- 241000239290 Araneae Species 0.000 claims 1
- 208000006820 Arthralgia Diseases 0.000 claims 1
- 208000008035 Back Pain Diseases 0.000 claims 1
- 208000013586 Complex regional pain syndrome type 1 Diseases 0.000 claims 1
- 208000011231 Crohn disease Diseases 0.000 claims 1
- 208000032131 Diabetic Neuropathies Diseases 0.000 claims 1
- 108010024636 Glutathione Proteins 0.000 claims 1
- 206010019233 Headaches Diseases 0.000 claims 1
- XUJNEKJLAYXESH-REOHCLBHSA-N L-Cysteine Chemical compound SC[C@H](N)C(O)=O XUJNEKJLAYXESH-REOHCLBHSA-N 0.000 claims 1
- 208000008930 Low Back Pain Diseases 0.000 claims 1
- 206010029174 Nerve compression Diseases 0.000 claims 1
- 208000028389 Nerve injury Diseases 0.000 claims 1
- 208000005890 Neuroma Diseases 0.000 claims 1
- 206010031009 Oral pain Diseases 0.000 claims 1
- 208000004983 Phantom Limb Diseases 0.000 claims 1
- 206010056238 Phantom pain Diseases 0.000 claims 1
- 208000004550 Postoperative Pain Diseases 0.000 claims 1
- 201000001947 Reflex Sympathetic Dystrophy Diseases 0.000 claims 1
- 241000239292 Theraphosidae Species 0.000 claims 1
- 208000005298 acute pain Diseases 0.000 claims 1
- 150000001413 amino acids Chemical group 0.000 claims 1
- 230000000202 analgesic effect Effects 0.000 claims 1
- 210000004899 c-terminal region Anatomy 0.000 claims 1
- 238000002512 chemotherapy Methods 0.000 claims 1
- XUJNEKJLAYXESH-UHFFFAOYSA-N cysteine Natural products SCC(N)C(O)=O XUJNEKJLAYXESH-UHFFFAOYSA-N 0.000 claims 1
- 235000018417 cysteine Nutrition 0.000 claims 1
- 239000003085 diluting agent Substances 0.000 claims 1
- 201000010099 disease Diseases 0.000 claims 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 229960003180 glutathione Drugs 0.000 claims 1
- 231100000869 headache Toxicity 0.000 claims 1
- 230000004968 inflammatory condition Effects 0.000 claims 1
- 208000002551 irritable bowel syndrome Diseases 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
- 210000005036 nerve Anatomy 0.000 claims 1
- 230000008764 nerve damage Effects 0.000 claims 1
- 208000021722 neuropathic pain Diseases 0.000 claims 1
- 201000001119 neuropathy Diseases 0.000 claims 1
- 230000007823 neuropathy Effects 0.000 claims 1
- 210000004197 pelvis Anatomy 0.000 claims 1
- 208000033808 peripheral neuropathy Diseases 0.000 claims 1
- 102000004196 processed proteins & peptides Human genes 0.000 claims 1
- 230000003381 solubilizing effect Effects 0.000 claims 1
- 239000002904 solvent Substances 0.000 claims 1
- 208000011580 syndromic disease Diseases 0.000 claims 1
- 208000004371 toothache Diseases 0.000 claims 1
- 230000000472 traumatic effect Effects 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US27233609P | 2009-09-15 | 2009-09-15 | |
| US61/272,336 | 2009-09-15 | ||
| PCT/IB2010/002275 WO2011033358A2 (en) | 2009-09-15 | 2010-09-13 | Novel peptides isolated from spider venom, and uses thereof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013504318A JP2013504318A (ja) | 2013-02-07 |
| JP2013504318A5 true JP2013504318A5 (https=) | 2013-10-17 |
| JP5555891B2 JP5555891B2 (ja) | 2014-07-23 |
Family
ID=43731158
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012528465A Expired - Fee Related JP5555891B2 (ja) | 2009-09-15 | 2010-09-13 | クモ毒から単離した新規ペプチド及びその使用 |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US8399026B2 (https=) |
| EP (1) | EP2504023B1 (https=) |
| JP (1) | JP5555891B2 (https=) |
| CN (1) | CN102573884B (https=) |
| AR (1) | AR078374A1 (https=) |
| AU (1) | AU2010296994B2 (https=) |
| BR (1) | BR112012005860A2 (https=) |
| CA (1) | CA2774350A1 (https=) |
| IL (1) | IL218382A0 (https=) |
| MX (1) | MX2012003078A (https=) |
| SG (1) | SG179101A1 (https=) |
| WO (1) | WO2011033358A2 (https=) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2830065A1 (en) * | 2011-03-16 | 2012-09-20 | Amgen Inc. | Potent and selective inhibitors of nav1.3 and nav1.7 |
| NZ621552A (en) * | 2011-08-24 | 2016-12-23 | Univ Queensland | Pest-controlling agents isolated from spider venom and uses thereof |
| US10414808B2 (en) | 2012-05-18 | 2019-09-17 | Janssen Biotech, Inc. | Huwentoxin-IV variants and methods of use |
| US9102751B2 (en) | 2012-05-18 | 2015-08-11 | Janssen Biotech, Inc. | Huwentoxin-IV variants and methods of use |
| EP3973981A1 (en) | 2012-05-18 | 2022-03-30 | Janssen Biotech, Inc. | Huwentoxin-iv variants and methods of use |
| JP6086378B2 (ja) * | 2012-11-30 | 2017-03-01 | 国立大学法人お茶の水女子大学 | 組み換えヒト膵臓リパーゼの調製方法 |
| US10344060B2 (en) | 2013-03-12 | 2019-07-09 | Amgen Inc. | Potent and selective inhibitors of Nav1.7 |
| AR096927A1 (es) | 2013-03-12 | 2016-02-10 | Amgen Inc | INHIBIDORES POTENTES Y SELECTIVOS DE NaV1.7 |
| US9624280B2 (en) | 2013-10-03 | 2017-04-18 | Janssen Biotech, Inc. | Protoxin-II variants and methods of use |
| GB201410108D0 (en) * | 2014-06-06 | 2014-07-23 | Univ Manchester | Peptides, and methods and apparatus utilising same |
| MA41642A (fr) | 2015-03-03 | 2018-01-09 | Janssen Biotech Inc | Variants de protoxine ii et méthodes d'utilisation |
| JP6985151B2 (ja) | 2015-04-02 | 2021-12-22 | ヤンセン バイオテツク，インコーポレーテツド | プロトキシン−ｉｉ変異体及びその使用方法 |
| CL2016002890A1 (es) * | 2016-11-14 | 2017-06-30 | Univ Antofagasta | Peptidos con actividad antimicrobiana |
| CN107141344A (zh) * | 2017-06-01 | 2017-09-08 | 长沙沁才生物科技有限公司 | 一种新型天然活性多肽spkp‑xi |
| CN107141343A (zh) * | 2017-06-01 | 2017-09-08 | 长沙沁才生物科技有限公司 | 一种活性多肽spkp‑xi的制备方法 |
| CN107163124A (zh) * | 2017-06-22 | 2017-09-15 | 长沙沁才生物科技有限公司 | SPNP‑IX在制备Nav1.3通道抑制剂中的应用 |
| CN107496904B (zh) * | 2017-09-21 | 2020-03-17 | 中南大学 | 多肽Lycosin-Ⅰ在制备抗炎和抗弓形虫药物中的应用 |
| CN108047323B (zh) * | 2017-12-20 | 2022-04-12 | 深圳羽众医药科技有限公司 | 一种固相片段法合成GpTx-1及其类似物和合成方法 |
| WO2022066767A2 (en) * | 2020-09-23 | 2022-03-31 | Aldevron, Llc | Potent and selective inhibitors of nav1.7 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4450150A (en) | 1973-05-17 | 1984-05-22 | Arthur D. Little, Inc. | Biodegradable, implantable drug delivery depots, and method for preparing and using the same |
| DE3463211D1 (en) | 1983-07-01 | 1987-05-21 | Battelle Memorial Institute | Biodegradable polypeptide and its use in the sustained release of medicaments |
| US5417986A (en) | 1984-03-16 | 1995-05-23 | The United States Of America As Represented By The Secretary Of The Army | Vaccines against diseases caused by enteropathogenic organisms using antigens encapsulated within biodegradable-biocompatible microspheres |
| US5776896A (en) * | 1996-01-03 | 1998-07-07 | Zeneca Limited | Analgesic peptides from venom of grammostola spatulata and use thereof |
| CN1133461C (zh) * | 2000-04-11 | 2004-01-07 | 厦门北大之路生物工程有限公司 | 虎纹捕鸟蜘蛛毒素提取物在制备镇痛药物中的应用 |
| WO2002007678A2 (en) * | 2000-07-21 | 2002-01-31 | University Of Utah Research Foundation | Mu-conopeptides |
| EP2412719A1 (en) * | 2002-12-02 | 2012-02-01 | Xenome Ltd | Chi-conotoxin peptides |
-
2010
- 2010-09-13 CN CN201080041208.8A patent/CN102573884B/zh not_active Expired - Fee Related
- 2010-09-13 CA CA2774350A patent/CA2774350A1/en not_active Abandoned
- 2010-09-13 SG SG2012017398A patent/SG179101A1/en unknown
- 2010-09-13 EP EP10816761.0A patent/EP2504023B1/en not_active Not-in-force
- 2010-09-13 JP JP2012528465A patent/JP5555891B2/ja not_active Expired - Fee Related
- 2010-09-13 AU AU2010296994A patent/AU2010296994B2/en not_active Ceased
- 2010-09-13 WO PCT/IB2010/002275 patent/WO2011033358A2/en not_active Ceased
- 2010-09-13 BR BR112012005860A patent/BR112012005860A2/pt not_active IP Right Cessation
- 2010-09-13 MX MX2012003078A patent/MX2012003078A/es active IP Right Grant
- 2010-09-14 US US12/881,269 patent/US8399026B2/en not_active Expired - Fee Related
- 2010-09-15 AR ARP100103359A patent/AR078374A1/es unknown
-
2012
- 2012-02-28 IL IL218382A patent/IL218382A0/en unknown
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