CN109265556A - 一种适用于静脉、腹腔或鼻腔给药的多肽 - Google Patents
一种适用于静脉、腹腔或鼻腔给药的多肽 Download PDFInfo
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- CN109265556A CN109265556A CN201811086053.4A CN201811086053A CN109265556A CN 109265556 A CN109265556 A CN 109265556A CN 201811086053 A CN201811086053 A CN 201811086053A CN 109265556 A CN109265556 A CN 109265556A
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/10—Fusion polypeptide containing a localisation/targetting motif containing a tag for extracellular membrane crossing, e.g. TAT or VP22
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Pain & Pain Management (AREA)
- Biophysics (AREA)
- Gastroenterology & Hepatology (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Tropical Medicine & Parasitology (AREA)
- Biochemistry (AREA)
- Rheumatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Abstract
Description
样品 | 理论MW | 实测m/z | 理论值与实测的差值 |
MⅦA | 2645.54 | 2639.0198 | 6.5202 |
MⅦA-a | 4186.0784 | 4180.0108 | 6.0676 |
MⅦA-b | 4243.0978 | 4237.0300 | 6.0678 |
MⅦA-c | 4299.1353 | 4292.0362 | 7.0991 |
MⅦA-d | 4356.1568 | 4351.0842 | 5.0726 |
Claims (10)
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CN201811086053.4A CN109265556B (zh) | 2018-09-18 | 2018-09-18 | 一种适用于静脉、腹腔或鼻腔给药的多肽 |
PCT/CN2018/124268 WO2020056991A1 (zh) | 2018-09-18 | 2018-12-27 | 一种适用于静脉、腹腔或鼻腔给药的多肽 |
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WO2020056987A1 (zh) * | 2018-09-18 | 2020-03-26 | 深圳瑞健生物科技有限公司 | 一种可通过血脑屏障的多肽 |
WO2020056985A1 (zh) * | 2018-09-18 | 2020-03-26 | 深圳瑞健生物科技有限公司 | 一种齐考诺肽和tat肽的融合多肽 |
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CN103784491A (zh) * | 2013-02-24 | 2014-05-14 | 王茜 | 一种仙人掌胶 |
KR20150050646A (ko) * | 2013-10-29 | 2015-05-11 | 삼성전자주식회사 | 융합 펩타이드 및 이의 세포막투과를 위한 용도 |
RU2016123345A (ru) * | 2016-05-18 | 2017-12-19 | Жильбер БЛЕЗ | Мультилекарственная инфузия для контроля боли |
CN109232744B (zh) * | 2018-09-18 | 2020-02-28 | 深圳瑞健生物科技有限公司 | 改进型齐考诺肽 |
CN109265558B (zh) * | 2018-09-18 | 2019-12-24 | 深圳瑞健生物科技有限公司 | 改进型齐考诺肽在制备药物中的应用 |
CN109265557B (zh) * | 2018-09-18 | 2019-12-24 | 深圳瑞健生物科技有限公司 | 一种齐考诺肽和tat肽的融合多肽在制备药物中的应用 |
CN109232746B (zh) * | 2018-09-18 | 2020-02-28 | 深圳瑞健生物科技有限公司 | 一种齐考诺肽和tat肽的融合多肽 |
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2018
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WO2020056985A1 (zh) * | 2018-09-18 | 2020-03-26 | 深圳瑞健生物科技有限公司 | 一种齐考诺肽和tat肽的融合多肽 |
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