JP2013501775A5 - - Google Patents
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- Publication number
- JP2013501775A5 JP2013501775A5 JP2012524330A JP2012524330A JP2013501775A5 JP 2013501775 A5 JP2013501775 A5 JP 2013501775A5 JP 2012524330 A JP2012524330 A JP 2012524330A JP 2012524330 A JP2012524330 A JP 2012524330A JP 2013501775 A5 JP2013501775 A5 JP 2013501775A5
- Authority
- JP
- Japan
- Prior art keywords
- mycobacterium bovis
- bovis bcg
- composition
- killed
- composition according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 241001467552 Mycobacterium bovis BCG Species 0.000 claims 14
- 239000000203 mixture Substances 0.000 claims 12
- 238000004108 freeze drying Methods 0.000 claims 6
- 230000001580 bacterial effect Effects 0.000 claims 4
- 238000007920 subcutaneous administration Methods 0.000 claims 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 3
- 230000002035 prolonged effect Effects 0.000 claims 2
- 102000004169 proteins and genes Human genes 0.000 claims 2
- 108090000623 proteins and genes Proteins 0.000 claims 2
- 201000001320 Atherosclerosis Diseases 0.000 claims 1
- 239000002260 anti-inflammatory agent Substances 0.000 claims 1
- 230000003110 anti-inflammatory effect Effects 0.000 claims 1
- 238000001035 drying Methods 0.000 claims 1
- 238000007710 freezing Methods 0.000 claims 1
- 230000008014 freezing Effects 0.000 claims 1
- 239000002955 immunomodulating agent Substances 0.000 claims 1
- 230000007774 longterm Effects 0.000 claims 1
- 238000000034 method Methods 0.000 claims 1
- 230000002265 prevention Effects 0.000 claims 1
- 239000012266 salt solution Substances 0.000 claims 1
- 230000003442 weekly effect Effects 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP09290627A EP2292260A1 (en) | 2009-08-13 | 2009-08-13 | Use of mycobacterium bovis BCG killed by extended freeze drying (EFD) for preventing or treating atherosclerosis |
| EP09290627.0 | 2009-08-13 | ||
| PCT/IB2010/053652 WO2011018769A1 (en) | 2009-08-13 | 2010-08-12 | Use of mycobacterium bovis bcg killed by extended freeze drying (efd) for preventing or treating atherosclerosis |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013501775A JP2013501775A (ja) | 2013-01-17 |
| JP2013501775A5 true JP2013501775A5 (enExample) | 2013-06-06 |
| JP5762407B2 JP5762407B2 (ja) | 2015-08-12 |
Family
ID=41402542
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012524330A Expired - Fee Related JP5762407B2 (ja) | 2009-08-13 | 2010-08-12 | アテローム性動脈硬化を予防又は治療するための、長期凍結乾燥（ｅｆｄ）により死滅したマイコバクテリウム・ボビスｂｃｇの使用 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US8414865B2 (enExample) |
| EP (2) | EP2292260A1 (enExample) |
| JP (1) | JP5762407B2 (enExample) |
| CA (1) | CA2770915C (enExample) |
| DK (1) | DK2464378T3 (enExample) |
| ES (1) | ES2563577T3 (enExample) |
| WO (1) | WO2011018769A1 (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102013106785B4 (de) | 2013-06-28 | 2018-11-29 | Pilz Auslandsbeteiligungen Gmbh | Verfahren zur Synchronisation eines Lichtgitters und auf diesem Verfahren beruhendes Lichtgitter |
| KR102393711B1 (ko) | 2013-10-17 | 2022-05-04 | 더 제너럴 하스피탈 코포레이션 | 자가면역 질환의 치료에 반응하는 대상체의 식별 방법 및 그의 치료를 위한 조성물 |
| JP6628071B2 (ja) * | 2015-04-28 | 2020-01-08 | 国立大学法人北海道大学 | 低密度リポタンパク質酸化抑制剤 |
| US11266730B2 (en) * | 2015-09-29 | 2022-03-08 | The General Hospital Corporation | Methods of treating and diagnosing disease using biomarkers for BCG therapy |
| US12491216B2 (en) | 2018-12-04 | 2025-12-09 | Neiker—Instituto Vasco De Investigacion Y Desarrollo Agrario, S.A. | Immunostimulant for use against pathogens |
| CN120677168A (zh) * | 2023-02-27 | 2025-09-19 | 明斯特威斯特法伦威廉大学 | 口服疫苗 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5075109A (en) | 1986-10-24 | 1991-12-24 | Southern Research Institute | Method of potentiating an immune response |
| US4897268A (en) | 1987-08-03 | 1990-01-30 | Southern Research Institute | Drug delivery system and method of making the same |
| US6350457B1 (en) * | 1999-06-02 | 2002-02-26 | Genesis Research & Development Corporation Limited | Methods and compounds for the treatment of immunologically-mediated diseases using mycobacterium vaccae |
| CN1602199B (zh) | 2001-12-11 | 2012-04-04 | 巴斯德研究院 | 用于治疗包含免疫失调的疾病的革兰氏阳性菌制剂 |
| CA2531261A1 (en) | 2005-12-21 | 2007-06-21 | Institut Pasteur | Control of intestinal inflammatory syndromes with a preparation of killed or non infectious bacteria |
| EP1916000A1 (en) * | 2006-10-26 | 2008-04-30 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Use of measles virus nucleoprotein for treating atherosclerosis |
| EP2087898A1 (en) * | 2008-02-06 | 2009-08-12 | Institut Pasteur | A preparation of mycobacterium bovis BCG killed by extended freeze drying (EFD) for treating rheumatoid arthritis |
-
2009
- 2009-08-13 EP EP09290627A patent/EP2292260A1/en not_active Withdrawn
-
2010
- 2010-08-12 US US13/389,929 patent/US8414865B2/en not_active Expired - Fee Related
- 2010-08-12 ES ES10754572.5T patent/ES2563577T3/es active Active
- 2010-08-12 EP EP10754572.5A patent/EP2464378B1/en not_active Not-in-force
- 2010-08-12 WO PCT/IB2010/053652 patent/WO2011018769A1/en not_active Ceased
- 2010-08-12 CA CA2770915A patent/CA2770915C/en not_active Expired - Fee Related
- 2010-08-12 DK DK10754572.5T patent/DK2464378T3/en active
- 2010-08-12 JP JP2012524330A patent/JP5762407B2/ja not_active Expired - Fee Related
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