DK2464378T3 - APPLICATION OF MYCOBACTERIUM BOVIS BCG HELD BY EXTENDED FREEZE DRYING (EFD) FOR PREVENTION OR TREATMENT OF Atherosclerosis - Google Patents

APPLICATION OF MYCOBACTERIUM BOVIS BCG HELD BY EXTENDED FREEZE DRYING (EFD) FOR PREVENTION OR TREATMENT OF Atherosclerosis Download PDF

Info

Publication number
DK2464378T3
DK2464378T3 DK10754572.5T DK10754572T DK2464378T3 DK 2464378 T3 DK2464378 T3 DK 2464378T3 DK 10754572 T DK10754572 T DK 10754572T DK 2464378 T3 DK2464378 T3 DK 2464378T3
Authority
DK
Denmark
Prior art keywords
efd
mice
bcg
pbs
atherosclerosis
Prior art date
Application number
DK10754572.5T
Other languages
Danish (da)
English (en)
Inventor
Gilles Marchal
Micheline Lagranderie
Isabelle Schwartz-Cornil
Original Assignee
Pasteur Institut
Agronomique Inst Nat Rech
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pasteur Institut, Agronomique Inst Nat Rech filed Critical Pasteur Institut
Application granted granted Critical
Publication of DK2464378T3 publication Critical patent/DK2464378T3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/04—Mycobacterium, e.g. Mycobacterium tuberculosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/58—Medicinal preparations containing antigens or antibodies raising an immune response against a target which is not the antigen used for immunisation

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Pulmonology (AREA)
  • Urology & Nephrology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DK10754572.5T 2009-08-13 2010-08-12 APPLICATION OF MYCOBACTERIUM BOVIS BCG HELD BY EXTENDED FREEZE DRYING (EFD) FOR PREVENTION OR TREATMENT OF Atherosclerosis DK2464378T3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP09290627A EP2292260A1 (en) 2009-08-13 2009-08-13 Use of mycobacterium bovis BCG killed by extended freeze drying (EFD) for preventing or treating atherosclerosis
PCT/IB2010/053652 WO2011018769A1 (en) 2009-08-13 2010-08-12 Use of mycobacterium bovis bcg killed by extended freeze drying (efd) for preventing or treating atherosclerosis

Publications (1)

Publication Number Publication Date
DK2464378T3 true DK2464378T3 (en) 2016-02-08

Family

ID=41402542

Family Applications (1)

Application Number Title Priority Date Filing Date
DK10754572.5T DK2464378T3 (en) 2009-08-13 2010-08-12 APPLICATION OF MYCOBACTERIUM BOVIS BCG HELD BY EXTENDED FREEZE DRYING (EFD) FOR PREVENTION OR TREATMENT OF Atherosclerosis

Country Status (7)

Country Link
US (1) US8414865B2 (enExample)
EP (2) EP2292260A1 (enExample)
JP (1) JP5762407B2 (enExample)
CA (1) CA2770915C (enExample)
DK (1) DK2464378T3 (enExample)
ES (1) ES2563577T3 (enExample)
WO (1) WO2011018769A1 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102013106785B4 (de) 2013-06-28 2018-11-29 Pilz Auslandsbeteiligungen Gmbh Verfahren zur Synchronisation eines Lichtgitters und auf diesem Verfahren beruhendes Lichtgitter
WO2015057968A2 (en) 2013-10-17 2015-04-23 The General Hospital Corporation Methods of identifying subjects responsive to treatment for an autoimmune disease and compositions for treating the same
JP6628071B2 (ja) * 2015-04-28 2020-01-08 国立大学法人北海道大学 低密度リポタンパク質酸化抑制剤
WO2017059132A1 (en) * 2015-09-29 2017-04-06 The General Hospital Corporation Methods of treating and diagnosing disease using biomarkers for bcg therapy
WO2020115161A1 (en) 2018-12-04 2020-06-11 Sabiotec Spin-Off Sl Immunostimulant for use against pathogens
WO2024180083A1 (en) * 2023-02-27 2024-09-06 Westfälische Wilhelms-Universität Münster Oral vaccine

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5075109A (en) 1986-10-24 1991-12-24 Southern Research Institute Method of potentiating an immune response
US4897268A (en) 1987-08-03 1990-01-30 Southern Research Institute Drug delivery system and method of making the same
US6350457B1 (en) * 1999-06-02 2002-02-26 Genesis Research & Development Corporation Limited Methods and compounds for the treatment of immunologically-mediated diseases using mycobacterium vaccae
ATE466585T1 (de) 2001-12-11 2010-05-15 Pasteur Institut Präparationen grampositiver bakterien zur behandlung von krankheiten mit immunfehlregulation
CA2531261A1 (en) 2005-12-21 2007-06-21 Institut Pasteur Control of intestinal inflammatory syndromes with a preparation of killed or non infectious bacteria
EP1916000A1 (en) * 2006-10-26 2008-04-30 INSERM (Institut National de la Santé et de la Recherche Médicale) Use of measles virus nucleoprotein for treating atherosclerosis
EP2087898A1 (en) * 2008-02-06 2009-08-12 Institut Pasteur A preparation of mycobacterium bovis BCG killed by extended freeze drying (EFD) for treating rheumatoid arthritis

Also Published As

Publication number Publication date
CA2770915C (en) 2017-12-05
WO2011018769A1 (en) 2011-02-17
EP2292260A1 (en) 2011-03-09
ES2563577T3 (es) 2016-03-15
JP5762407B2 (ja) 2015-08-12
US8414865B2 (en) 2013-04-09
CA2770915A1 (en) 2011-02-17
US20120201856A1 (en) 2012-08-09
EP2464378A1 (en) 2012-06-20
JP2013501775A (ja) 2013-01-17
EP2464378B1 (en) 2015-11-11

Similar Documents

Publication Publication Date Title
CA2770915C (en) Use of mycobacterium bovis bcg killed by extended freeze drying (efd) for preventing or treating atherosclerosis
Smits et al. Protective effect of Schistosoma mansoni infection on allergic airway inflammation depends on the intensity and chronicity of infection
Bach et al. The hygiene hypothesis: an explanation for the increased frequency of insulin-dependent diabetes
Persson et al. Mycobacterium tuberculosis-induced apoptotic neutrophils trigger a pro-inflammatory response in macrophages through release of heat shock protein 72, acting in synergy with the bacteria
JP2018524393A (ja) 免疫応答を誘導するための新規方法
Gao et al. Immunomodulation therapy of diabetes by oral administration of a surfactin lipopeptide in NOD mice
Ovchinnikova et al. Mycobacterium bovis BCG killed by extended freeze‐drying induces an immunoregulatory profile and protects against atherosclerosis
US9415077B2 (en) Effect of an attenuated Bordetella strain against allergic disease
Qu et al. L-theanine modulates intestine-specific immunity by regulating the differentiation of CD4+ T cells in ovalbumin-sensitized mice
AU2002356387B2 (en) Gram positive bacteria preparations for the treatment of diseases comprising an immune dysregulation
Silvane et al. A vaccine based on Kunitz-type molecule confers protection against Fasciola hepatica challenge by inducing IFN-γ and antibody immune responses through IL-17A production
Taguchi et al. Adjuvant effect of Japanese herbal medicines on the mucosal type 1 immune responses to human papillomavirus (HPV) E7 in mice immunized orally with Lactobacillus-based therapeutic HPV vaccine in a synergistic manner
Huang et al. Engineered porous/hollow Burkholderia pseudomallei loading tumor lysate as a vaccine
Singh et al. Gut microbe-derived outer membrane vesicles: a potential platform to control cecal load of Campylobacter jejuni
Peres et al. Previous contact with Strongyloides venezuelensis contributed to prevent insulitis in MLD-STZ diabetes
Kim et al. Therapeutic effects of Echinococcus granulosus cystic fluid on allergic airway inflammation
Baker et al. Intradermal vaccination with a Pseudomonas aeruginosa vaccine adjuvanted with a mutant bacterial ADP-ribosylating enterotoxin protects against acute pneumonia
Chaudhari et al. Construction of an attenuated Salmonella delivery system harboring genes encoding various virulence factors of avian pathogenic Escherichia coli and its potential as a candidate vaccine for chicken colibacillosis
WO2016154730A1 (en) Gut anti-inflammatory agents for regulation of high blood glucose levels
Bahroudi et al. Immunomodulatory effects of mesenchymal stem cell-conditioned media on lipopolysaccharide of Vibrio cholerae as a vaccine candidate
You et al. Immunogenicity and protective efficacy of heterologous prime-boost regimens with mycobacterial vaccines and recombinant adenovirus-and poxvirus-vectored vaccines against murine tuberculosis
Rodriguez et al. Proteoliposomes from Mycobacterium smegmatis induce immune cross-reactivity against Mycobacterium tuberculosis antigens in mice
Jurado-Martín et al. Proteomic approach to identify host cell attachment proteins provides protective Pseudomonas aeruginosa vaccine antigen FtsZ
CN108697784B (zh) 用于对屋尘螨来源的过敏原的超敏反应的免疫调节剂
RU2473365C1 (ru) Вакцина mycobacterium tuberculosis