|
US11111544B2
(en)
|
2005-07-29 |
2021-09-07 |
Natera, Inc. |
System and method for cleaning noisy genetic data and determining chromosome copy number
|
|
US9424392B2
(en)
|
2005-11-26 |
2016-08-23 |
Natera, Inc. |
System and method for cleaning noisy genetic data from target individuals using genetic data from genetically related individuals
|
|
US10081839B2
(en)
|
2005-07-29 |
2018-09-25 |
Natera, Inc |
System and method for cleaning noisy genetic data and determining chromosome copy number
|
|
US8532930B2
(en)
|
2005-11-26 |
2013-09-10 |
Natera, Inc. |
Method for determining the number of copies of a chromosome in the genome of a target individual using genetic data from genetically related individuals
|
|
US10083273B2
(en)
|
2005-07-29 |
2018-09-25 |
Natera, Inc. |
System and method for cleaning noisy genetic data and determining chromosome copy number
|
|
US11111543B2
(en)
|
2005-07-29 |
2021-09-07 |
Natera, Inc. |
System and method for cleaning noisy genetic data and determining chromosome copy number
|
|
US20110033862A1
(en)
*
|
2008-02-19 |
2011-02-10 |
Gene Security Network, Inc. |
Methods for cell genotyping
|
|
US20110092763A1
(en)
*
|
2008-05-27 |
2011-04-21 |
Gene Security Network, Inc. |
Methods for Embryo Characterization and Comparison
|
|
CN102171565B
(zh)
*
|
2008-08-04 |
2015-04-29 |
纳特拉公司 |
等位基因调用和倍性调用的方法
|
|
US8962247B2
(en)
|
2008-09-16 |
2015-02-24 |
Sequenom, Inc. |
Processes and compositions for methylation-based enrichment of fetal nucleic acid from a maternal sample useful for non invasive prenatal diagnoses
|
|
US8476013B2
(en)
|
2008-09-16 |
2013-07-02 |
Sequenom, Inc. |
Processes and compositions for methylation-based acid enrichment of fetal nucleic acid from a maternal sample useful for non-invasive prenatal diagnoses
|
|
US20120252015A1
(en)
*
|
2011-02-18 |
2012-10-04 |
Bio-Rad Laboratories |
Methods and compositions for detecting genetic material
|
|
US20120185176A1
(en)
|
2009-09-30 |
2012-07-19 |
Natera, Inc. |
Methods for Non-Invasive Prenatal Ploidy Calling
|
|
WO2011066476A1
(en)
*
|
2009-11-25 |
2011-06-03 |
Quantalife, Inc. |
Methods and compositions for detecting genetic material
|
|
US20190010543A1
(en)
|
2010-05-18 |
2019-01-10 |
Natera, Inc. |
Methods for simultaneous amplification of target loci
|
|
US9677118B2
(en)
|
2014-04-21 |
2017-06-13 |
Natera, Inc. |
Methods for simultaneous amplification of target loci
|
|
US11332793B2
(en)
|
2010-05-18 |
2022-05-17 |
Natera, Inc. |
Methods for simultaneous amplification of target loci
|
|
US12221653B2
(en)
|
2010-05-18 |
2025-02-11 |
Natera, Inc. |
Methods for simultaneous amplification of target loci
|
|
US10316362B2
(en)
|
2010-05-18 |
2019-06-11 |
Natera, Inc. |
Methods for simultaneous amplification of target loci
|
|
US11408031B2
(en)
|
2010-05-18 |
2022-08-09 |
Natera, Inc. |
Methods for non-invasive prenatal paternity testing
|
|
US12152275B2
(en)
|
2010-05-18 |
2024-11-26 |
Natera, Inc. |
Methods for non-invasive prenatal ploidy calling
|
|
US11332785B2
(en)
|
2010-05-18 |
2022-05-17 |
Natera, Inc. |
Methods for non-invasive prenatal ploidy calling
|
|
CA2798758C
(en)
|
2010-05-18 |
2019-05-07 |
Natera, Inc. |
Methods for non-invasive prenatal ploidy calling
|
|
US11322224B2
(en)
|
2010-05-18 |
2022-05-03 |
Natera, Inc. |
Methods for non-invasive prenatal ploidy calling
|
|
US11339429B2
(en)
|
2010-05-18 |
2022-05-24 |
Natera, Inc. |
Methods for non-invasive prenatal ploidy calling
|
|
US11326208B2
(en)
|
2010-05-18 |
2022-05-10 |
Natera, Inc. |
Methods for nested PCR amplification of cell-free DNA
|
|
US11939634B2
(en)
|
2010-05-18 |
2024-03-26 |
Natera, Inc. |
Methods for simultaneous amplification of target loci
|
|
US8603742B2
(en)
|
2010-07-06 |
2013-12-10 |
University of Pittsburgh—of the Commonwealth System of Higher Education |
Methods for the diagnosis of fetal disease
|
|
US20130261003A1
(en)
|
2010-08-06 |
2013-10-03 |
Ariosa Diagnostics, In. |
Ligation-based detection of genetic variants
|
|
US8700338B2
(en)
|
2011-01-25 |
2014-04-15 |
Ariosa Diagnosis, Inc. |
Risk calculation for evaluation of fetal aneuploidy
|
|
US11203786B2
(en)
|
2010-08-06 |
2021-12-21 |
Ariosa Diagnostics, Inc. |
Detection of target nucleic acids using hybridization
|
|
US10533223B2
(en)
|
2010-08-06 |
2020-01-14 |
Ariosa Diagnostics, Inc. |
Detection of target nucleic acids using hybridization
|
|
US20130040375A1
(en)
|
2011-08-08 |
2013-02-14 |
Tandem Diagnotics, Inc. |
Assay systems for genetic analysis
|
|
US20140342940A1
(en)
|
2011-01-25 |
2014-11-20 |
Ariosa Diagnostics, Inc. |
Detection of Target Nucleic Acids using Hybridization
|
|
ES2770342T3
(es)
|
2010-12-22 |
2020-07-01 |
Natera Inc |
Procedimientos para pruebas prenatales no invasivas de paternidad
|
|
US8756020B2
(en)
|
2011-01-25 |
2014-06-17 |
Ariosa Diagnostics, Inc. |
Enhanced risk probabilities using biomolecule estimations
|
|
CA2824387C
(en)
|
2011-02-09 |
2019-09-24 |
Natera, Inc. |
Methods for non-invasive prenatal ploidy calling
|
|
EP3483285B1
(en)
|
2011-02-09 |
2021-07-14 |
Bio-Rad Laboratories, Inc. |
Analysis of nucleic acids
|
|
US12097495B2
(en)
*
|
2011-02-18 |
2024-09-24 |
Bio-Rad Laboratories, Inc. |
Methods and compositions for detecting genetic material
|
|
AU2012236200B2
(en)
*
|
2011-03-30 |
2015-05-14 |
Verinata Health, Inc. |
Method for verifying bioassay samples
|
|
US8712697B2
(en)
|
2011-09-07 |
2014-04-29 |
Ariosa Diagnostics, Inc. |
Determination of copy number variations using binomial probability calculations
|
|
WO2013130857A1
(en)
*
|
2012-02-29 |
2013-09-06 |
Bio Dx, Inc. |
Defining diagnostic and therapeutic targets of conserved fetal dna in maternal circulating blood
|
|
EP3757210B1
(en)
|
2012-03-02 |
2022-08-24 |
Sequenom, Inc. |
Methods for enriching cancer nucleic acid from a biological sample
|
|
WO2013138527A1
(en)
|
2012-03-13 |
2013-09-19 |
The Chinese University Of Hong Kong |
Methods for analyzing massively parallel sequencing data for noninvasive prenatal diagnosis
|
|
HK1205204A1
(en)
|
2012-03-26 |
2015-12-11 |
约翰霍普金斯大学 |
Rapid aneuploidy detection
|
|
US10504613B2
(en)
|
2012-12-20 |
2019-12-10 |
Sequenom, Inc. |
Methods and processes for non-invasive assessment of genetic variations
|
|
US9920361B2
(en)
|
2012-05-21 |
2018-03-20 |
Sequenom, Inc. |
Methods and compositions for analyzing nucleic acid
|
|
MX2014015425A
(es)
*
|
2012-06-15 |
2015-07-14 |
Harry Stylli |
Metodos para detectar enfermedades o condiciones.
|
|
EP2872648B1
(en)
|
2012-07-13 |
2019-09-04 |
Sequenom, Inc. |
Processes and compositions for methylation-based enrichment of fetal nucleic acid from a maternal sample useful for non-invasive prenatal diagnoses
|
|
US9206417B2
(en)
|
2012-07-19 |
2015-12-08 |
Ariosa Diagnostics, Inc. |
Multiplexed sequential ligation-based detection of genetic variants
|
|
US20140100126A1
(en)
|
2012-08-17 |
2014-04-10 |
Natera, Inc. |
Method for Non-Invasive Prenatal Testing Using Parental Mosaicism Data
|
|
US10706957B2
(en)
|
2012-09-20 |
2020-07-07 |
The Chinese University Of Hong Kong |
Non-invasive determination of methylome of tumor from plasma
|
|
US9732390B2
(en)
|
2012-09-20 |
2017-08-15 |
The Chinese University Of Hong Kong |
Non-invasive determination of methylome of fetus or tumor from plasma
|
|
BR112015006183B1
(pt)
*
|
2012-09-20 |
2022-04-26 |
The Chinese University Of Hong Kong |
Métodos para analisar uma amostra biológica de um organismo, para determinar um primeiro perfil de metilação de uma amostra biológica de um organismo, para detecção de uma anormalidade cromossômica de uma amostra biológica de um organismo e para estimar um nível de metilação do dna em uma amostra biológica de um organismo, produto de computador, e, kit para análise de dna fetal
|
|
CN104838013A
(zh)
*
|
2012-09-26 |
2015-08-12 |
新加坡科技研究局 |
用于唐氏综合症产前诊断的生物标志物
|
|
US20130189684A1
(en)
*
|
2013-03-12 |
2013-07-25 |
Sequenom, Inc. |
Quantification of cell-specific nucleic acid markers
|
|
US11060145B2
(en)
|
2013-03-13 |
2021-07-13 |
Sequenom, Inc. |
Methods and compositions for identifying presence or absence of hypermethylation or hypomethylation locus
|
|
AU2014278730B2
(en)
*
|
2013-06-13 |
2020-12-10 |
F. Hoffmann-La Roche Ag |
Statistical analysis for non-invasive sex chromosome aneuploidy determination
|
|
WO2015002845A1
(en)
*
|
2013-07-01 |
2015-01-08 |
Anderson Cindy |
Biomarker for preeclampsia
|
|
WO2015013885A1
(zh)
*
|
2013-07-30 |
2015-02-05 |
深圳华大基因科技有限公司 |
确定核酸混合物中核酸组成的方法
|
|
WO2015048535A1
(en)
|
2013-09-27 |
2015-04-02 |
Natera, Inc. |
Prenatal diagnostic resting standards
|
|
US10577655B2
(en)
|
2013-09-27 |
2020-03-03 |
Natera, Inc. |
Cell free DNA diagnostic testing standards
|
|
US10262755B2
(en)
|
2014-04-21 |
2019-04-16 |
Natera, Inc. |
Detecting cancer mutations and aneuploidy in chromosomal segments
|
|
KR102846299B1
(ko)
*
|
2013-10-04 |
2025-08-13 |
시쿼넘, 인코포레이티드 |
유전적 변이의 비침습 평가를 위한 방법 및 프로세스
|
|
US20160340740A1
(en)
*
|
2014-01-30 |
2016-11-24 |
The Regents Of The University Of California |
Methylation haplotyping for non-invasive diagnosis (monod)
|
|
EP3736344A1
(en)
|
2014-03-13 |
2020-11-11 |
Sequenom, Inc. |
Methods and processes for non-invasive assessment of genetic variations
|
|
EP3561075A1
(en)
|
2014-04-21 |
2019-10-30 |
Natera, Inc. |
Detecting mutations in tumour biopsies and cell-free samples
|
|
US12492429B2
(en)
|
2014-04-21 |
2025-12-09 |
Natera, Inc. |
Detecting mutations and ploidy in chromosomal segments
|
|
CA2985134A1
(en)
*
|
2014-05-09 |
2015-11-12 |
Sebastian Gromminger |
Detection of dna that originates from a specific cell-type and related methods
|
|
EP2942401A1
(en)
|
2014-05-09 |
2015-11-11 |
Lifecodexx AG |
Detection of DNA that originates from a specific cell-type
|
|
EP2942400A1
(en)
|
2014-05-09 |
2015-11-11 |
Lifecodexx AG |
Multiplex detection of DNA that originates from a specific cell-type
|
|
CN106488981A
(zh)
*
|
2014-05-15 |
2017-03-08 |
科尔贝恩科斯公司 |
用于诊断测试的胎儿有核红细胞(nrbcs)的制备
|
|
US20180173846A1
(en)
|
2014-06-05 |
2018-06-21 |
Natera, Inc. |
Systems and Methods for Detection of Aneuploidy
|
|
CN107075582A
(zh)
*
|
2014-09-29 |
2017-08-18 |
富士胶片株式会社 |
胎儿的染色体非整倍性的非侵入性判别方法及判别系统
|
|
WO2016176846A1
(zh)
*
|
2015-05-06 |
2016-11-10 |
安诺优达基因科技(北京)有限公司 |
检测染色体非整倍性的试剂盒、装置和方法
|
|
CN104789686B
(zh)
*
|
2015-05-06 |
2018-09-07 |
浙江安诺优达生物科技有限公司 |
检测染色体非整倍性的试剂盒和装置
|
|
EP4428863A3
(en)
|
2015-05-11 |
2024-12-11 |
Natera, Inc. |
Methods and compositions for determining ploidy
|
|
WO2017012544A1
(en)
|
2015-07-20 |
2017-01-26 |
The Chinese University Of Hong Kong |
Methylation pattern analysis of haplotypes in tissues in dna mixture
|
|
CN105132572B
(zh)
*
|
2015-09-25 |
2018-03-02 |
邯郸市康业生物科技有限公司 |
一种无创产前筛查21‑三体综合征试剂盒
|
|
KR101848438B1
(ko)
*
|
2015-10-29 |
2018-04-13 |
바이오코아 주식회사 |
디지털 pcr을 이용한 산전진단 방법
|
|
CN108368548A
(zh)
*
|
2015-11-09 |
2018-08-03 |
普罗格尼迪公司 |
用于确定dna分子的来源的方法
|
|
EP3168309B8
(en)
*
|
2015-11-10 |
2020-06-03 |
Eurofins LifeCodexx GmbH |
Detection of foetal chromosomal aneuploidies using dna regions that are differentially methylated between the foetus and the pregnant female
|
|
US10982286B2
(en)
|
2016-01-22 |
2021-04-20 |
Mayo Foundation For Medical Education And Research |
Algorithmic approach for determining the plasma genome abnormality PGA and the urine genome abnormality UGA scores based on cell free cfDNA copy number variations in plasma and urine
|
|
DK3443119T3
(da)
|
2016-04-15 |
2022-05-23 |
Natera Inc |
Fremgangsmåde til bestemmelse af lunge cancer
|
|
CN106086243A
(zh)
*
|
2016-08-01 |
2016-11-09 |
王燕芸 |
一种无创式检测怀孕中胎儿是否健康的系统及其应用
|
|
EP3518974A4
(en)
|
2016-09-29 |
2020-05-27 |
Myriad Women's Health, Inc. |
NON-INVASIVE PRENATAL SCREENING USING DYNAMIC ITERATIVE DEEP OPTIMIZATION
|
|
WO2018067517A1
(en)
|
2016-10-04 |
2018-04-12 |
Natera, Inc. |
Methods for characterizing copy number variation using proximity-litigation sequencing
|
|
EP3524687A4
(en)
*
|
2016-10-05 |
2019-11-06 |
FUJIFILM Corporation |
METHOD FOR DETERMINING THE NUMBER OF LOCUS REQUIRED AND METHOD FOR DETERMINING THE NUMBER OF SNP LOCUS REQUIRED
|
|
GB201618485D0
(en)
|
2016-11-02 |
2016-12-14 |
Ucl Business Plc |
Method of detecting tumour recurrence
|
|
US10011870B2
(en)
|
2016-12-07 |
2018-07-03 |
Natera, Inc. |
Compositions and methods for identifying nucleic acid molecules
|
|
CN106916893A
(zh)
*
|
2016-12-26 |
2017-07-04 |
中国科学院上海微系统与信息技术研究所 |
一种基于数字pcr芯片的基因甲基化程度定量方法
|
|
EP3575399B1
(en)
*
|
2017-01-24 |
2024-10-09 |
BGI Shenzhen |
Exosomal dna-based method for performing non-invasive prenatal diagnosis and application thereof
|
|
US10894976B2
(en)
|
2017-02-21 |
2021-01-19 |
Natera, Inc. |
Compositions, methods, and kits for isolating nucleic acids
|
|
US12084720B2
(en)
|
2017-12-14 |
2024-09-10 |
Natera, Inc. |
Assessing graft suitability for transplantation
|
|
US12398389B2
(en)
|
2018-02-15 |
2025-08-26 |
Natera, Inc. |
Methods for isolating nucleic acids with size selection
|
|
JP7573443B2
(ja)
|
2018-04-14 |
2024-10-25 |
ナテラ， インコーポレイテッド |
循環腫瘍ｄｎａの個別化された検出を用いる癌検出およびモニタリングの方法
|
|
US12234509B2
(en)
|
2018-07-03 |
2025-02-25 |
Natera, Inc. |
Methods for detection of donor-derived cell-free DNA
|
|
CN109022541A
(zh)
*
|
2018-07-16 |
2018-12-18 |
苏州大学附属第二医院 |
一种浓集胎儿游离dna的试剂盒、方法及其应用
|
|
CN109136363A
(zh)
*
|
2018-08-31 |
2019-01-04 |
领航基因科技（杭州）有限公司 |
一种检测胎儿染色体非整数倍的试剂盒和检测胎儿甲基化dna拷贝数的方法
|
|
EP3980559A1
(en)
|
2019-06-06 |
2022-04-13 |
Natera, Inc. |
Methods for detecting immune cell dna and monitoring immune system
|
|
CN114929893A
(zh)
*
|
2019-06-24 |
2022-08-19 |
齐罗马科德公司 |
差异定量核酸的方法
|
|
CN110964073B
(zh)
*
|
2019-11-28 |
2023-06-02 |
上海市第一妇婴保健院 |
用于捕获胎儿特有dna甲基化修饰结合蛋白的探针及方法
|
|
CN113046435B
(zh)
*
|
2021-05-14 |
2023-10-03 |
吉林大学第一医院 |
一种用于制备产前胎儿21-三体综合征检测的pcr反应体系的特异性引物
|