JP2013238605A5 - - Google Patents

Download PDF

Info

Publication number
JP2013238605A5
JP2013238605A5 JP2013123680A JP2013123680A JP2013238605A5 JP 2013238605 A5 JP2013238605 A5 JP 2013238605A5 JP 2013123680 A JP2013123680 A JP 2013123680A JP 2013123680 A JP2013123680 A JP 2013123680A JP 2013238605 A5 JP2013238605 A5 JP 2013238605A5
Authority
JP
Japan
Prior art keywords
ion
molecular
computer
ion source
information
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2013123680A
Other languages
English (en)
Japanese (ja)
Other versions
JP2013238605A (ja
JP5718982B2 (ja
Filing date
Publication date
Priority claimed from US09/615,102 external-priority patent/US6498342B1/en
Application filed filed Critical
Publication of JP2013238605A publication Critical patent/JP2013238605A/ja
Publication of JP2013238605A5 publication Critical patent/JP2013238605A5/ja
Application granted granted Critical
Publication of JP5718982B2 publication Critical patent/JP5718982B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

JP2013123680A 2000-07-13 2013-06-12 イオン分離装置 Expired - Lifetime JP5718982B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/615,102 2000-07-13
US09/615,102 US6498342B1 (en) 1997-06-02 2000-07-13 Ion separation instrument

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP2002512998A Division JP2004504696A (ja) 2000-07-13 2001-07-10 イオン分離装置

Publications (3)

Publication Number Publication Date
JP2013238605A JP2013238605A (ja) 2013-11-28
JP2013238605A5 true JP2013238605A5 (enExample) 2015-03-12
JP5718982B2 JP5718982B2 (ja) 2015-05-13

Family

ID=24463987

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2002512998A Pending JP2004504696A (ja) 2000-07-13 2001-07-10 イオン分離装置
JP2013123680A Expired - Lifetime JP5718982B2 (ja) 2000-07-13 2013-06-12 イオン分離装置

Family Applications Before (1)

Application Number Title Priority Date Filing Date
JP2002512998A Pending JP2004504696A (ja) 2000-07-13 2001-07-10 イオン分離装置

Country Status (7)

Country Link
US (2) US6498342B1 (enExample)
EP (1) EP1305819B1 (enExample)
JP (2) JP2004504696A (enExample)
AU (2) AU7195601A (enExample)
CA (1) CA2413287C (enExample)
IL (2) IL153598A0 (enExample)
WO (1) WO2002007185A1 (enExample)

Families Citing this family (80)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6960761B2 (en) * 1997-06-02 2005-11-01 Advanced Research & Technology Institute Instrument for separating ions in time as functions of preselected ion mobility and ion mass
US6504149B2 (en) 1998-08-05 2003-01-07 National Research Council Canada Apparatus and method for desolvating and focussing ions for introduction into a mass spectrometer
US7005632B2 (en) 2002-04-12 2006-02-28 Sionex Corporation Method and apparatus for control of mobility-based ion species identification
US6815669B1 (en) 1999-07-21 2004-11-09 The Charles Stark Draper Laboratory, Inc. Longitudinal field driven ion mobility filter and detection system
US7157700B2 (en) * 2001-06-30 2007-01-02 Sionex Corporation System for collection of data and identification of unknown ion species in an electric field
US6806463B2 (en) 1999-07-21 2004-10-19 The Charles Stark Draper Laboratory, Inc. Micromachined field asymmetric ion mobility filter and detection system
US7399958B2 (en) 1999-07-21 2008-07-15 Sionex Corporation Method and apparatus for enhanced ion mobility based sample analysis using various analyzer configurations
US6815668B2 (en) * 1999-07-21 2004-11-09 The Charles Stark Draper Laboratory, Inc. Method and apparatus for chromatography-high field asymmetric waveform ion mobility spectrometry
AU3907401A (en) * 2000-03-14 2001-09-24 Ca Nat Research Council Apparatus and method for trandem icp/faims/ms
US6586732B2 (en) * 2001-02-20 2003-07-01 Brigham Young University Atmospheric pressure ionization ion mobility spectrometry
US7084395B2 (en) * 2001-05-25 2006-08-01 Ionwerks, Inc. Time-of-flight mass spectrometer for monitoring of fast processes
ITMI20011193A1 (it) * 2001-06-06 2002-12-06 Getters Spa Metodo per la misura mediante spettroscopia di mobilita' ionica dellaconcentrazione di acqua in argon, idrogeno, azoto e elio
US7586088B2 (en) * 2001-06-21 2009-09-08 Micromass Uk Limited Mass spectrometer and method of mass spectrometry
CA2391060C (en) * 2001-06-21 2011-08-09 Micromass Limited Mass spectrometer
US6987262B2 (en) * 2002-02-08 2006-01-17 Ionalytics Corporation FAIMS apparatus and method for detecting trace amounts of a vapour in a carrier gas
US7026612B2 (en) * 2002-02-08 2006-04-11 Ionalytics Corporation FAIMS apparatus and method using carrier gases that contain a trace amount of a dopant species
WO2003067244A2 (en) * 2002-02-08 2003-08-14 Ionalytics Corporation Faims with non-destructive detection of selectively transmitted ions
US7122794B1 (en) 2002-02-21 2006-10-17 Sionex Corporation Systems and methods for ion mobility control
GB2390478B (en) 2002-05-17 2004-06-02 Micromass Ltd Mass spectrometer
US6906319B2 (en) * 2002-05-17 2005-06-14 Micromass Uk Limited Mass spectrometer
US6791078B2 (en) 2002-06-27 2004-09-14 Micromass Uk Limited Mass spectrometer
US7071467B2 (en) * 2002-08-05 2006-07-04 Micromass Uk Limited Mass spectrometer
DE10236344B4 (de) * 2002-08-08 2007-03-29 Bruker Daltonik Gmbh Ionisieren an Atmosphärendruck für massenspektrometrische Analysen
WO2005050159A2 (en) * 2003-10-14 2005-06-02 Washington State University Research Foundation Ion mobility spectrometry method and apparatus
EP1690074A2 (en) * 2003-11-25 2006-08-16 Sionex Corporation Mobility based apparatus and methods using dispersion characteristics, sample fragmentation, and/or pressure control to improve analysis of a sample
EP1695374A4 (en) * 2003-11-25 2008-04-16 Syft Technologies Ltd IMPROVEMENTS RELATING TO SIFT-MS INSTRUMENTS
EP1697024B1 (en) * 2003-12-18 2017-08-30 DH Technologies Development Pte. Ltd. Methods and apparatus for enhanced ion based sample detection using selective pre-separation and amplification
US20050133712A1 (en) * 2003-12-18 2005-06-23 Predicant Biosciences, Inc. Scan pipelining for sensitivity improvement of orthogonal time-of-flight mass spectrometers
CA2551991A1 (en) 2004-01-13 2005-07-28 Sionex Corporation Methods and apparatus for enhanced sample identification based on combined analytical techniques
EP1735613A4 (en) * 2004-02-02 2009-03-11 Sionex Corp COMPACT SAMPLE ANALYSIS SYSTEMS AND RELATED METHODS BASED ON COMBINED CHROMATOGRAPHY AND MOBILITY SPECTROMETRY TECHNIQUES
US6958473B2 (en) * 2004-03-25 2005-10-25 Predicant Biosciences, Inc. A-priori biomarker knowledge based mass filtering for enhanced biomarker detection
GB0408751D0 (en) 2004-04-20 2004-05-26 Micromass Ltd Mass spectrometer
WO2005106450A1 (en) * 2004-04-28 2005-11-10 Sionex Corporation System and method for ion species analysis with enhanced condition control and data interpretation using differential mobility spectrometers
US20050269508A1 (en) * 2004-06-03 2005-12-08 Lippa Timothy P Apparatus and methods for detecting compounds using mass spectra
JP4513488B2 (ja) 2004-10-06 2010-07-28 株式会社日立製作所 イオンモビリティー分析装置及びイオンモビリティー分析方法
GB0424426D0 (en) 2004-11-04 2004-12-08 Micromass Ltd Mass spectrometer
ATE512458T1 (de) * 2004-12-07 2011-06-15 Micromass Ltd Massenspektrometer
US7148474B2 (en) * 2005-04-11 2006-12-12 Battelle Memorial Institute Device for two-dimensional gas-phase separation and characterization of ion mixtures
EP1920243B1 (en) * 2005-04-29 2015-09-09 DH Technologies Development Pte. Ltd. Compact gas chromatography and ion mobility based sample analysis systems, methods, and devices
WO2006130474A2 (en) 2005-05-27 2006-12-07 Ionwerks, Inc. Multi-beam ion mobility time-of-flight mass spectrometer with bipolar ion extraction and zwitterion detection
GB2441943A (en) 2005-07-26 2008-03-19 Sionex Corp Ultra compact ion mobility based analyzer system and method
US7560688B2 (en) * 2005-10-14 2009-07-14 Washington State University Mass analysis of mobility selected ion populations
GB0524972D0 (en) * 2005-12-07 2006-01-18 Micromass Ltd Mass spectrometer
US10276358B2 (en) * 2006-01-02 2019-04-30 Excellims Corporation Chemically modified ion mobility separation apparatus and method
WO2007120373A2 (en) * 2006-01-26 2007-10-25 Sionex Corporation Differential mobility spectrometer analyzer and pre-filter apparatus, methods and systems
US7943901B2 (en) * 2006-11-28 2011-05-17 Excellims Corporation Practical ion mobility spectrometer apparatus and methods for chemical and/or biological detection
US7510245B2 (en) * 2006-07-12 2009-03-31 Honda Motor Co., Ltd Seat belt webbing enclosure
US7598488B2 (en) 2006-09-20 2009-10-06 Park Melvin A Apparatus and method for field asymmetric ion mobility spectrometry combined with mass spectrometry
EP2126961B1 (en) * 2007-02-24 2014-06-18 Sociedad Europea De Analisis Diferencial De Movilidad S.L. Method to accurately discriminate gas phase ions with several filtering devices in tandem
DE102007017055B4 (de) * 2007-04-11 2011-06-22 Bruker Daltonik GmbH, 28359 Messung der Mobilität massenselektierter Ionen
JP4862738B2 (ja) * 2007-05-08 2012-01-25 株式会社日立製作所 イオン移動度分析装置およびイオン移動度分離／質量分析複合装置
US8334506B2 (en) 2007-12-10 2012-12-18 1St Detect Corporation End cap voltage control of ion traps
US7973277B2 (en) 2008-05-27 2011-07-05 1St Detect Corporation Driving a mass spectrometer ion trap or mass filter
GB0810125D0 (en) * 2008-06-03 2008-07-09 Thermo Fisher Scient Bremen Collosion cell
GB2454962B (en) * 2008-07-25 2009-10-28 Kratos Analytical Ltd Method and apparatus for ion axial spatial distribution focusing
WO2010091512A1 (en) * 2009-02-13 2010-08-19 Dh Technologies Development Pte. Ltd. Apparatus and method of photo-fragmentation
CA2759247C (en) * 2009-04-21 2018-05-08 Excellims Corporation Intelligently controlled spectrometer methods and apparatus
US8581177B2 (en) * 2011-04-11 2013-11-12 Thermo Finnigan Llc High duty cycle ion storage/ion mobility separation mass spectrometer
GB201122178D0 (en) 2011-12-22 2012-02-01 Thermo Fisher Scient Bremen Method of tandem mass spectrometry
GB2497948A (en) 2011-12-22 2013-07-03 Thermo Fisher Scient Bremen Collision cell for tandem mass spectrometry
GB201205009D0 (en) 2012-03-22 2012-05-09 Micromass Ltd Multi-dimensional survey scans for improved data dependent acquisitions (DDA)
GB201208812D0 (en) * 2012-05-18 2012-07-04 Micromass Ltd Cryogenic collision cell
CA2903623C (en) 2013-03-06 2021-04-20 Micromass Uk Limited Optimised ion mobility separation timescales for targeted ions
EP2965342B1 (en) 2013-03-06 2020-08-05 Micromass UK Limited Time shift for improved digitisation of ion analysis
GB201304039D0 (en) * 2013-03-06 2013-04-17 Micromass Ltd Time shift improved IMS digitisation
US9459194B2 (en) 2013-03-14 2016-10-04 Cardio Metrix Apparatuses, processes, and systems for measuring particle size distribution and concentration
GB2517670B (en) * 2013-03-15 2020-04-29 Smiths Detection Watford Ltd Ion modification
JP5997650B2 (ja) * 2013-04-15 2016-09-28 株式会社日立ハイテクノロジーズ 分析システム
EP3146322B1 (en) 2014-05-22 2024-07-10 W. Henry Benner Instruments for measuring ion size distribution and concentration
WO2015185941A1 (en) 2014-06-06 2015-12-10 Micromass Uk Limited Mobility selective attenuation
GB2531292B (en) * 2014-10-14 2019-06-12 Smiths Detection Watford Ltd Method and apparatus
JP6439080B1 (ja) * 2015-10-07 2018-12-19 バテル メモリアル インスティチュート 交流波形を用いるイオン移動度分離のための方法および装置
US10030658B2 (en) 2016-04-27 2018-07-24 Mark W. Wood Concentric vane compressor
US11480178B2 (en) 2016-04-27 2022-10-25 Mark W. Wood Multistage compressor system with intercooler
WO2018084868A1 (en) 2016-11-07 2018-05-11 Wood Mark W Scroll compressor with circular surface terminations
US11686309B2 (en) 2016-11-07 2023-06-27 Mark W. Wood Scroll compressor with circular surface terminations
EP3578966B1 (en) 2018-06-04 2025-11-05 Bruker Scientific LLC Separation of ions according to ion mobility with enhanced resolving power for mass spectrometric analysis
GB2576003B (en) * 2018-07-31 2021-02-03 Smiths Detection Watford Ltd Ion gate configured to fragment ions in ion mobility spectrometry
JP7176570B2 (ja) * 2018-10-25 2022-11-22 株式会社島津製作所 質量分析装置およびプログラム
US12033843B2 (en) * 2020-03-26 2024-07-09 Agilent Technologies, Inc. Mass spectrometry ION source

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3668383A (en) * 1969-01-09 1972-06-06 Franklin Gno Corp Apparatus and methods for separating, detecting, and measuring trace gases
JPS5528018B1 (enExample) * 1969-04-01 1980-07-24
US3621240A (en) 1969-05-27 1971-11-16 Franklin Gro Corp Apparatus and methods for detecting and identifying trace gases
US3626178A (en) * 1970-02-20 1971-12-07 Franklin Gno Corp Gas or liquid chromatograph with detector employing ion-molecule reactions and ion drift
US3626179A (en) * 1970-04-03 1971-12-07 Franklin Gno Corp High temperature method and apparatus for analyzing gaseous samples
US3812355A (en) 1971-12-09 1974-05-21 Gno F Corp Apparatus and methods for measuring ion mass as a function of mobility
US3845301A (en) 1972-05-10 1974-10-29 Franklin Gno Corp Apparatus and methods employing ion analysis apparatus with enhanced gas flow
US3902064A (en) 1974-07-12 1975-08-26 Robert A Young Ion mobility mass spectrometer
US4234791A (en) * 1978-11-13 1980-11-18 Research Corporation Tandem quadrupole mass spectrometer for selected ion fragmentation studies and low energy collision induced dissociator therefor
US4261698A (en) 1980-01-23 1981-04-14 International Business Machines Corporation Trace oxygen detector
US4855595A (en) * 1986-07-03 1989-08-08 Allied-Signal Inc. Electric field control in ion mobility spectrometry
US4885076A (en) * 1987-04-06 1989-12-05 Battelle Memorial Institute Combined electrophoresis-electrospray interface and method
WO1989006044A1 (en) 1987-12-24 1989-06-29 Unisearch Limited Mass spectrometer
US4987767A (en) * 1989-06-09 1991-01-29 Research Corporation Technologies, Inc. Exposive detection screening system
US5070240B1 (en) 1990-08-29 1996-09-10 Univ Brigham Young Apparatus and methods for trace component analysis
US5210412A (en) 1991-01-31 1993-05-11 Wayne State University Method for analyzing an organic sample
JPH08507926A (ja) 1993-03-19 1996-08-27 シーケノム・インコーポレーテツド エキソヌクレアーゼ分解を介した質量分析法によるｄｎａ配列決定
JPH07211282A (ja) * 1994-01-19 1995-08-11 Shimadzu Corp 質量分析計
US5420424A (en) * 1994-04-29 1995-05-30 Mine Safety Appliances Company Ion mobility spectrometer
US5504326A (en) 1994-10-24 1996-04-02 Indiana University Foundation Spatial-velocity correlation focusing in time-of-flight mass spectrometry
DE19511333C1 (de) 1995-03-28 1996-08-08 Bruker Franzen Analytik Gmbh Verfahren und Vorrichtung für orthogonalen Einschuß von Ionen in ein Flugzeit-Massenspektrometer
JPH095298A (ja) 1995-06-06 1997-01-10 Varian Assoc Inc 四重極イオントラップ内の選択イオン種を検出する方法
US5811059A (en) * 1995-10-16 1998-09-22 The United States Of America As Represented By The Secretary Of The Army Automated, on-demand ion mobility spectrometry analysis of gas chromatograph effluents
US5905258A (en) * 1997-06-02 1999-05-18 Advanced Research & Techology Institute Hybrid ion mobility and mass spectrometer
US6323482B1 (en) * 1997-06-02 2001-11-27 Advanced Research And Technology Institute, Inc. Ion mobility and mass spectrometer
JP2002503808A (ja) * 1998-02-11 2002-02-05 ヘイリー、ローレンス・ブイ Ｇｃ／ｉｍｓを使用する手持ち型検出システム
WO2000008456A1 (en) * 1998-08-05 2000-02-17 National Research Council Canada Method for separation and enrichment of isotopes in gaseous phase

Similar Documents

Publication Publication Date Title
JP2013238605A5 (enExample)
Wu et al. Contributions of immunoaffinity chromatography to deep proteome profiling of human biofluids
Blue et al. Recent advances in capillary ultrahigh pressure liquid chromatography
Lista et al. Biological and methodical challenges of blood-based proteomics in the field of neurological research
Causon et al. Theoretical evaluation of peak capacity improvements by use of liquid chromatography combined with drift tube ion mobility-mass spectrometry
MX2017015229A (es) Metodos para la cuantificacion espectrometrica de masas de analitos extraidos de un dispositivo de micromuestreo.
JP2014202582A5 (enExample)
WO2018026591A3 (en) Systems and methods for integrating ion mobility and ion trap mass spectrometers
Shvartsburg et al. High-resolution differential ion mobility separations using planar analyzers at elevated dispersion fields
Steenbergen et al. Electronic effects on the melting of small gallium clusters
Distler et al. Biomedical applications of ion mobility-enhanced data-independent acquisition-based label-free quantitative proteomics
MX2014013901A (es) Amplificador de transimpedancia capacitiva con desfase.
Blagojevic et al. Differential mobility spectrometry of isomeric protonated dipeptides: modifier and field effects on ion mobility and stability
Shvartsburg et al. Isotopic effect on ion mobility and separation of isotopomers by high-field ion mobility spectrometry
Wu et al. A miniaturized linear wire ion trap with electron ionization and single photon ionization sources
Shvartsburg et al. Accelerated high-resolution differential ion mobility separations using hydrogen
JP2018036147A5 (enExample)
Ma et al. Application and recovery of ionic liquids in the preparative separation of four flavonoids from Rhodiola rosea by on‐line three‐dimensional liquid chromatography
JP2016530517A5 (enExample)
Olof Johansson et al. Hot electron production and diffuse excited states in C70, C82, and Sc3N@ C80 characterized by angular-resolved photoelectron spectroscopy
Wu et al. Conformers, electronic states, and diabolical conical intersections in the valence photoelectron spectroscopy of halocyclohexanes
Garcia et al. Photoelectron circular dichroism spectroscopy in an orbitally congested system: The terpene endoborneol
MX379918B (es) Metodos para analisis y resolucion de preparaciones de dianhidrogalactitol y derivados o analogos del mismo.
RU2015104248A (ru) Способ идентификации органических соединений методом хроматр-масс-спектрометрии
Rodríguez et al. Conventional matrices loaded onto a graphene layer enhances MALDI-TOF/TOF signal: its application to improve detection of phosphorylated peptides