JP2013205405A - Automatic analyzer and inspection system - Google Patents

Abstract

PROBLEM TO BE SOLVED: To provide an automatic analyzer and an inspection system capable of preventing deterioration of analytical data due to a partial component contained in a sample stored in a sample container.SOLUTION: The automatic analyzer includes: a sample dispensation probe 16 for performing dispensation for sucking a sample stored in a sample container 17 and discharging the sucked sample to a reaction container 3; a liquid surface detector 16a for detecting the sample in the sample container 17 by contact with the sample dispensation probe 16; and an analysis control part 25 for moving the sample dispensation probe 16 on the basis of an analysis value obtained from a blood analyzer 110 and a detection signal detected by the liquid surface detector 16a. The analysis control part 25, when the analysis value is a preset upper limit value or less, stops the sample dispensation probe 16 on a first suction position P21 downward by a first distance D1 from the contact position with the sample in the sample container 17, and when the analysis value exceeds the upper limit value, stops the sample dispensation probe 16 on a second suction position P22 downward from the first suction position P21.

Description

  Embodiments described herein relate generally to an automatic analyzer and a test system including a dispensing probe for dispensing a sample.

  The automatic analyzer is intended for biochemical test items and immunological test items. Then, by measuring the change in color tone and turbidity caused by the reaction of the mixture of the test sample collected from the test sample and the reagent of each test item, by optically measuring with a photometric unit of a spectrophotometer or turbidimetry Analytical data represented by the concentration of the test item component, the activity of the enzyme, and the like are obtained.

  In this automatic analyzer, an inspection target item selected from a plurality of inspection items is analyzed for each test sample. Then, the sample dispensing probe sucks the test sample in the sample container and discharges it to the reaction container. The reagent dispensing probe sucks the reagent in the reagent container and discharges it to the reaction container. In addition, the photometric unit measures the sample liquid and the mixed solution of the reagent discharged into the reaction container.

  By the way, there is a sample container such as a blood collection tube for storing blood collected from a subject. The sample container is centrifuged to separate it into an upper layer sample made of serum or plasma and a lower layer sample containing blood cell components and the like, and then placed in a sample container holder. When the sample dispensing probe sucks the sample in the sample container, in order to suppress contamination due to contact with the sample on the outer wall of the sample dispensing probe, the sample is taken at the suction position where the lower end has entered about several mm from the liquid surface. Stop the dispensing probe.

Japanese Patent No. 3664456

  However, the lower layer sample floats on the liquid level of the upper layer sample in the sample container, and a part of the suspended lower layer sample is mixed into the upper layer sample sucked by the sample dispensing probe stopped at the suction position. There is a problem that the analysis data of the inspection item to be analyzed deteriorates.

  The embodiments are made to solve the above-described problems, and provide an automatic analyzer and a test system that can prevent deterioration of analysis data due to some components contained in a sample contained in a sample container. For the purpose.

  In order to achieve the above object, an automatic analyzer according to an embodiment dispenses a sample contained in a sample container and sucks and discharges the sample in an automatic analyzer that measures the mixed liquid. A dispensing probe for detecting the sample, a detector for detecting the sample by contact between the sample and the dispensing probe, an analysis value obtained by analyzing a predetermined component contained in the sample, and the detector A drive control unit that moves the dispensing probe based on the detected signal, and the drive control unit contacts the dispensing probe with the sample when the analysis value is less than or equal to a preset upper limit value. When the analysis value exceeds the upper limit value, the dispensing probe is moved to the second suction position below the first suction position. Stop at position And wherein the door.

1 is a block diagram showing a configuration of an inspection system according to an embodiment. The perspective view which shows the structure of the analysis part which concerns on embodiment. The figure which shows the sample dispensing probe used for dispensing of the sample which concerns on embodiment, a sample dispensing arm, a sample dispensing pump, a liquid level detector, and a sample container. The figure which shows each position which the sample dispensing probe which concerns on embodiment stops. The figure which shows an example of a structure of the washing | cleaning part which concerns on embodiment.

  Hereinafter, embodiments will be described with reference to the drawings.

  FIG. 1 is a block diagram illustrating a configuration of an inspection system according to the embodiment. This test system 200 includes, for example, a general-purpose automatic analyzer 100 that analyzes biochemical test items and the like installed in a medical institution, and a blood analyzer 110 that analyzes general blood test items such as red blood cells, white blood cells, and platelets. And. In addition, a data storage device 120 that stores analysis data obtained by analysis of the automatic analyzer 100, the blood analyzer 110, and the like is provided. And it connects by the network 130 so that communication is possible between each apparatuses, such as the automatic analyzer 100, the blood analyzer 110, and the data storage apparatus 120. FIG.

  The automatic analyzer 100 dispenses a sample such as a standard sample or a test sample and a reagent used for analysis of each inspection item, measures the mixed solution, and generates standard data or test data. An analysis control unit 25 that drives each analysis unit of the analysis unit 24 to control dispensing operation, measurement operation, washing operation, etc., and processes standard data and test data generated by the analysis unit 24 to perform calibration. And a data processing unit 30 for generating data and analysis data.

  The automatic analyzer 100 includes an output unit 40 that prints out and displays the calibration data and analysis data generated by the data processing unit 30, an operation unit 45 that inputs various command signals, and the like, and a data storage device 120. Transmission / reception unit 50 that receives analysis data from and transmits analysis data to the data storage device 120, and a system control unit 60 that controls the analysis control unit 25, data processing unit 30, output unit 40, and transmission / reception unit 50 in an integrated manner. And.

  FIG. 2 is a perspective view showing the configuration of the analysis unit 24. The analysis unit 24 includes a sample container 17 that stores a standard sample and a test sample for each inspection item, and a sample disk 5 that holds the sample container 17. In addition, a reagent container 6 containing a first reagent and a second reagent system that react with the components of the test item included in each sample of the standard sample and the test sample, and the reagent container 6 are held movably. A reagent rack 1a and a reagent storage 1 for keeping the reagent container 6 held in the reagent rack 1a cold are provided.

  In addition, a reagent container 7 that stores a second reagent that is paired with a first reagent in a two-reagent system, a reagent rack 2a that holds the reagent container 7 movably, and a reagent container 7 that is held in the reagent rack 2a And a reagent storage 2 for keeping cold. Moreover, the reaction disk 4 which hold | maintains the some reaction container 3 arrange | positioned on the periphery rotatably is provided.

  In addition, a sample dispensing probe 16 that performs dispensing to suck and discharge the sample stored in the sample container 17 held on the sample disk 5 into the reaction container 3, and the sample container 17 held on the sample disk 5 Is provided with a liquid level detector 16 a that detects the sample by contact between the sample and the sample dispensing probe 16. Further, the sample dispensing pump 16b that causes the sample dispensing probe 16 to suck and discharge the sample, the sample dispensing arm 10 that holds the sample dispensing probe 16 so as to be rotatable and vertically movable, and the sample dispensing probe 16 And a cleaning unit 70 for cleaning the water.

  In addition, a first reagent dispensing probe 14 for aspirating the first reagent in the reagent container 6 held in the reagent rack 1a and dispensing it into the reaction container 3 from which the sample has been discharged, and the first reagent dispensing A first reagent dispensing arm 8 that holds the dispensing probe 14 so as to be rotatable and vertically movable, a cleaning unit 71 that cleans the first reagent dispensing probe 14, a sample discharged into the reaction container 3, and a first reagent And a first stirrer 18 for stirring the mixed solution.

  The second reagent dispensing probe 15 for aspirating the second reagent in the reagent container 7 held in the reagent rack 2a and dispensing it into the reaction container 3 from which the first reagent has been discharged; A second reagent dispensing arm 9 that holds the reagent dispensing probe 15 so as to be rotatable and vertically movable, and a cleaning unit 72 that cleans the second reagent dispensing probe 15 are provided. In addition, a second stirrer 19 that stirs the mixed solution of the sample, the first reagent, and the second reagent in the reaction vessel 3, and a photometric unit that optically measures the mixed solution in the reaction vessel 3 by irradiating light. 13 and a reaction container cleaning unit 12 that cleans the inside of the reaction container 3 that has been measured by the photometry unit 13.

  Then, the photometry unit 13 irradiates the reaction container 3 with light, and detects light transmitted through the liquid mixture containing the standard sample and the test sample in the reaction container 3. Based on the detected detection signal, for example, standard data or test data represented by absorbance data is generated, and the generated standard data or test data is output to the data processing unit 30.

  The analysis control unit 25 includes a mechanism that drives each analysis unit of the analysis unit 24 and a control unit that controls the mechanism. Then, the sample disk 5, the reagent rack 1a, and the reagent rack 2a are driven to rotate. In addition, the sample dispensing arm 10, the first reagent dispensing arm 8, and the second reagent dispensing arm 9 are rotated and driven up and down, respectively, so that the sample dispensing probe 16, the first reagent dispensing probe 14, and the second reagent dispensing arm 9 are rotated. The reagent dispensing probe 15 is moved. Further, the reaction container cleaning unit 12 is driven up and down. Further, the sample dispensing pump 16b is driven to suck and discharge. Further, the cleaning units 70, 71 and 72 are driven to be cleaned.

  The data processing unit 30 shown in FIG. 1 includes a calculation unit 31 that processes standard data and test data output from the photometry unit 13 of the analysis unit 24 to generate calibration data and analysis data for each inspection item, A data storage unit 32 for storing the standard data and analysis data generated by the unit 31.

  The calculation unit 31 generates calibration data representing the relationship between the standard value and the standard data for each inspection item from the standard data output from the photometry unit 13 and the standard value preset for the standard sample of the standard data. The generated calibration data is output to the output unit 40 and stored in the data storage unit 32.

  Further, the calibration data of the inspection item corresponding to the test data output from the photometry unit 13 is read from the data storage unit 32. Then, analysis data represented by a concentration value or an activity value is generated from the test data output from the photometry unit 13 using the read calibration data. Then, the generated analysis data is output to the data storage unit 32, the output unit 40, and the system control unit 60.

  The data storage unit 32 includes a memory device such as a hard disk, and stores the calibration data output from the calculation unit 31 for each inspection item. Moreover, the analysis data of each inspection item output from the calculation unit 31 is stored for each test sample.

  The output unit 40 includes a printing unit 41 that prints out calibration data and analysis data output from the calculation unit 31 of the data processing unit 30 and a display unit 42 that displays and outputs the calibration data. The printing unit 41 includes a printer or the like, and prints the calibration data and analysis data output from the calculation unit 31 on printer paper or the like according to a preset format.

  The display unit 42 includes a monitor such as a CRT or a liquid crystal panel, and displays calibration data and analysis data output from the calculation unit 31. In addition, an analysis parameter setting screen for inputting, for example, a sample amount and a reagent amount to be discharged into the reaction container 3 which are analysis parameters of the test item, an ID for identifying the subject, and a subject identified by this ID A sample information setting screen for inputting inspection items to be inspected is displayed.

  The operation unit 45 includes input devices such as a keyboard, a mouse, a button, and a touch key panel, and inputs analysis parameters for each inspection item, and inputs each ID and inspection item. Also, a predetermined test item (test item that affects) that can be analyzed by the blood analyzer 110 and an upper limit value of this test item are input. In addition, among the inspection items that can be analyzed by the automatic analyzer 100, the inspection items that are affected by the components of the inspecting inspection items are input.

  The transmission / reception unit 50 transmits the ID and analysis data of each inspection item generated by the calculation unit 31 of the data processing unit 30 and supplied from the system control unit 60 to the data storage device 120 via the network 130. In addition, request information requesting the analysis value of the inspecting inspection item is transmitted to the data storage device 120. In addition, the analysis value of the inspection item that affects the request information that is returned from the data storage device 120 is received.

  The system control unit 60 includes a CPU and a storage circuit, and stores input information such as analysis parameters, IDs, and inspection items of each inspection item input by the operation from the operation unit 45 in the storage circuit. Based on the above, the analysis control unit 25, the data processing unit 30, the output unit 40, and the transmission / reception unit 50 are controlled to control the entire system.

Next, an outline of a sample dispensing operation in the analysis unit 24 will be described with reference to FIGS.
FIG. 3 is a view showing a sample dispensing probe 16, a sample dispensing arm 10, a sample dispensing pump 16b, a liquid level detector 16a, and a sample container 17 used for dispensing a sample. The sample dispensing probe 16 is composed of a tube extending in the vertical direction, the upper end is held by the sample dispensing arm 10, and the upper end is a tube 161 filled with a sample dispensing pump 16b and a pressure transmission medium such as pure water. It communicates with. Further, it is electrically connected to the liquid level detector 16a.

  The sample container 17 includes a test sample collected from a subject, for example, blood separated by a centrifuge and separated into an upper layer, for example, an upper layer sample containing serum and a red blood cell, white blood cell and platelet separated into a lower layer It is a blood collection tube which accommodates a lower layer sample. Thus, by using a blood collection tube as the sample container 17, the trouble of transferring from the blood collection tube to another container can be saved.

  The liquid level detector 16 a has a capacitance sensor, for example, and detects the upper layer sample in the sample container 17 from a change in capacitance due to contact between the sample and the sample dispensing probe 16. Then, the detected detection signal is output to the analysis control unit 25.

  Then, as shown in FIG. 4, the analysis control unit 25 rotates the sample dispensing arm 10 to move the sample dispensing probe 16 along the circular trajectory indicated by the broken line with the arrow R1 direction and the R1 direction. Move in the direction of arrow R2 in the opposite direction. And it stops at the 1st washing position P1 which can be washed by washing part 70, for example. Further, the sample is stopped at the sample position P2 above the sample container 17 held by the sample disk 5. Moreover, it stops at the container position P3 above the reaction container 3.

  The analysis control unit 25 also includes detection signals for detecting the upper layer sample in the sample container 17 held on the sample disk 5 by the liquid level detector 16a, and inspection items that have an influence supplied from the system control unit 60. Based on the analysis value, the upper limit value of the analysis value, and the information of the inspection item to be affected, the sample dispensing arm 10 is driven downward to move the sample dispensing probe 16 downward from the sample position P2. Then, the sample dispensing probe 16 is stopped at a position where the lower end portion enters the sample in the sample container 17.

  And, when suctioning when the analysis value of the inspecting test item is less than or equal to a preset upper limit value, or inspection items other than the test item affected when the analysis value exceeds the upper limit value At the time of suction for analysis, as shown in FIG. 3A, the first suction position P21 below the first distance D1 from the position at which the sample dispensing probe 16 is in contact with the upper layer sample in the sample container 17. Stop at. Then, the sample dispensing pump 16b is driven to suck, and the sample dispensing probe 16 stopped at the first suction position P21 is caused to suck the upper layer sample.

  In this way, by stopping the sample dispensing probe 16 at the first suction position P21, it is possible to prevent contact between the sample and the portion unnecessary for suction other than the first distance D1 on the outer wall of the sample dispensing probe 16, and the sample. Contamination by the sample on the outer wall of the sample dispensing probe 16 can be suppressed.

  When the analysis value of the test item that has an effect exceeds the upper limit value, the sample dispensing probe 16 is moved as shown in FIG. The first suction position P21 is lower than the first suction position P21 and is stopped at the second suction position P22 below the second distance D2 from the position in contact with the upper layer sample in the sample container 17. Then, the sample dispensing pump 16b is driven to suck and the sample dispensing probe 16 stopped at the second suction position P22 is caused to suck the upper layer sample.

  Here, the test item that affects is, for example, platelets, and the test item that is affected is lactate dehydrogenase. When the number of platelets obtained by analyzing the blood before being separated into the upper layer sample detected by the liquid level detector 16a exceeds the upper limit of 500000 / μL, for example, it is detected by the liquid level detector 16a. In addition, there is a possibility that platelets are floating on the serum surface of the upper layer sample. If platelets are floating on the serum surface, the platelets are mixed into the serum sucked by the sample dispensing probe 16 stopped at the first suction position P21, for example, 2 mm below from the position in contact with the serum. Since platelets contain highly active lactate dehydrogenase, analysis of lactate dehydrogenase using serum contaminated with platelets shows that the analytical data shows abnormal values higher than normal values. Therefore, if platelets are floating on the serum surface, the sample dispensing probe 16 stopped at the second suction position P22, for example, 10 mm below from the position in contact with the serum, sucks the serum, thereby contaminating the platelets. It is possible to prevent the deterioration of analysis data.

  If the test item to be affected is, for example, platelets and the test item to be affected is lactate dehydrogenase, it is separated into an upper layer sample containing serum and a lower layer sample containing red blood cells, white blood cells, and platelets by blood centrifugation. By removing the serum from the collected blood tube and transferring it to another sample container 17, platelets floating on the serum liquid surface of the collected blood tube are mixed with the formation, and deterioration of the analysis data can be prevented.

  In this way, when suction is performed when the analysis value of the inspecting inspection item is an upper layer sample separated from the sample exceeding the upper limit, and the inspection item to be analyzed using the upper layer sample is the inspection item to be affected Then, the sample dispensing probe 16 is stopped at the second suction position P22 below the first suction position P21, thereby mixing the inspection item components that affect the upper layer sample sucked by the sample dispensing probe 16. Can be prevented. Thereby, it is possible to prevent the analysis data of the affected inspection item from deteriorating.

  Further, the analysis control unit 25 drives the sample dispensing arm 10 downward to move the sample dispensing probe 16 downward from the container position P3. Then, the sample dispensing probe 16 is stopped at the discharge position where the lower end is located near the bottom surface after entering the reaction container 3 held by the reaction disk 4. Then, the sample dispensing pump 16b is driven to discharge, and the upper sample is discharged to the sample dispensing probe 16 stopped at the discharge position.

  FIG. 5 is a diagram illustrating an example of the configuration of the cleaning unit 70. FIG. 5A shows the cleaning position of the sample dispensing probe 16 that sucked the sample at the first suction position P21, and FIG. 5B shows the sample dispensing that sucked the sample at the second suction position P22. The cleaning position of the probe 16 is shown.

  The cleaning unit 70 is a cleaning tank 701 for cleaning the sample dispensing probe 16, a discharge port 702 provided in the cleaning tank 701, and a cleaning for supplying a cleaning liquid for cleaning the outer wall of the sample dispensing probe 16 to the discharge port 702. A pump 703 is provided.

  As shown in FIG. 5A, the analysis control unit 25 stops the sample dispensing probe 16 that has finished dispensing the sample that has been aspirated only at the first aspiration position P21 at the first washing position P1. . Then, the cleaning pump 703 is driven for cleaning, and the cleaning liquid is discharged from the discharge port 702. When the discharged cleaning liquid hits the sample dispensing probe 16 stopped at the first suction position P21, the entire outer wall in contact with the sample of the sample dispensing probe 16 is washed. Further, the entire inner wall of the sample dispensing probe 16 in contact with the sample is cleaned by discharging the sample dispensing pump 16b and supplying a pressure transmission medium as a cleaning liquid into the sample dispensing probe 16 via the tube 161. To do.

  As described above, after the dispensing of the sample sucked only at the first suction position P21 is completed, the sample dispensing probe 16 is stopped at the first cleaning position P1, thereby contacting the sample of the sample dispensing probe 16. The outer wall can be cleaned using a cleaning liquid.

  Further, as shown in FIG. 5B, the analysis control unit 25 performs the first cleaning on the sample dispensing probe 16 that has finished dispensing the sample that has been aspirated at the second aspiration position P22. Stop at a second cleaning position P11 below the position P1. Then, the cleaning pump 703 is driven for cleaning, and the cleaning liquid is discharged from the discharge port 702. When the discharged cleaning liquid hits the sample dispensing probe 16 stopped at the second suction position P22 and falls, the entire outer wall in contact with the sample of the sample dispensing probe 16 is washed. Further, the entire inner wall of the sample dispensing probe 16 in contact with the sample is cleaned by discharging the sample dispensing pump 16b and supplying a pressure transmission medium as a cleaning liquid into the sample dispensing probe 16 via the tube 161. To do.

  In this way, after the dispensing of the sample that has been sucked at the second suction position P22 is completed, the sample dispensing probe 16 is stopped at the second cleaning position P11, thereby contacting the sample of the sample dispensing probe 16 The inner and outer walls can be cleaned using a cleaning liquid.

  Hereinafter, an example of the operation of the inspection system 200 will be described with reference to FIGS. 1 to 5.

  In the storage circuit of the system control unit 60 in the automatic analyzer 100, the inspection item A1 that is input from the operation unit 45, the inspection item B1 that is affected by the inspection item A1, and the upper limit value of the inspection item A1 are stored. Has been.

  A test sample collected from the subject M to perform the inspection is accommodated in the two sample containers 17. Then, the analysis items A1 to A3 included in the test sample stored in one sample container 17 are analyzed by the blood analyzer 110, and the analysis values of the test items A1 to A3 are transmitted to the data storage device 120. Thus, the data storage device 120 stores the analysis values of the test items A1 to A3 of the subject M obtained from the blood analyzer 110.

  On the other hand, the other sample container 17 that has been subjected to a centrifuge and separated into an upper layer and a lower layer is placed on the sample disk 5 of the analysis unit 24. When the measurement start is input after the ID and the inspection items B1 to Bn are input from the operation unit 45 in order to inspect the subject M, the system control unit 60 checks the inspection items B1 to B1 of the subject M. The transmission / reception unit 50 is instructed to inquire about the analysis value of the inspection item A1 that affects the inspection item B1 that is included in Bn.

  The transmission / reception unit 50 transmits the request information including the ID of the subject M and the test item A1 to the data storage device 120, whereby the test item A1 using the test sample of the subject M returned from the data storage device 120. The analysis value obtained from the blood analyzer 110 by the analysis is received.

  The system control unit 60 supplies the analysis value of the inspection item A1 received by the transmission / reception unit 50, the upper limit value of the analysis value, and the analysis parameters of the inspection items B1 to Bn to the analysis control unit 25. The analysis control unit 25 performs drive control for dispensing the sample in the sample container 17 held on the sample disk 5 to the reaction container 3 based on the analysis parameters of the inspection items B1 to Bn supplied from the system control unit 60. Do. Then, the sample dispensing probe 16 is moved from the home position, for example, the first cleaning position P1, and stopped at the sample position P2.

  After the sample dispensing probe 16 stops at the sample position P2, the analysis control unit 25 moves the sample dispensing probe 16 downward from the sample position P2. The upper layer sample in the sample container 17 held on the sample disk 5 is detected by the detection signal detected by the liquid level detector 16a, the analysis value of the inspecting inspection item A1, the upper limit value of this analysis value, and the influence. Based on the information of the inspection item B1, the sample dispensing probe 16 is stopped at the position where the lower end portion enters the upper layer sample in the sample container 17.

  If the analysis value of the test item that affects the sample is equal to or lower than the upper limit value, the sample dispensing probe 16 is stopped at the first suction position P21. Further, when the analysis value of the inspecting inspection item A1 exceeds the upper limit value, the sample dispensing probe 16 is set to the first during the aspiration for analyzing the inspection items B2 to Bn other than the affected inspection item B1. At the suction position P21. Then, the sample dispensing pump 16b is driven to suck, and the sample dispensing probe 16 stopped at the first suction position P21 is caused to suck the upper layer sample.

  Further, when the analysis value of the inspecting test item A1 exceeds the upper limit value, the sample dispensing probe 16 is stopped at the second suction position P22 during the suction for analyzing the affected test item B1. . Then, the sample dispensing pump 16b is driven to suck and the sample dispensing probe 16 stopped at the second suction position P22 is caused to suck the upper layer sample.

  When the sample dispensing probe 16 that has finished dispensing the test sample of the subject M performs suction only at the first suction position P21, the analysis control unit 25 moves the sample dispensing probe 16 to the first cleaning position. Stop at P1. Then, the cleaning pump 703 and the sample dispensing pump 16b are driven to clean the entire inner wall of the sample dispensing probe 16 in contact with the test sample.

  In addition, when the sample dispensing probe 16 that has finished dispensing the test sample of the subject M has aspirated at the second suction position P22, the sample dispensing probe 16 is moved at the second cleaning position P11. Stop. Then, the cleaning pump 703 and the sample dispensing pump 16b are driven to clean the entire inner wall of the sample dispensing probe 16 in contact with the test sample.

  According to the embodiment described above, the inspection item A1 for inspecting the subject M by inputting the inspection item A1 affected by the operation unit 45, the upper limit value of the inspection item A1, and the inspection item B1 affected by the inspection item A1. When the analysis value obtained from the blood analyzer 110 by the analysis of is less than or equal to the upper limit value, the sample dispensing probe 16 is moved to the first aspiration during the aspiration for analyzing the test items B1 to Bn for inspecting the subject M. It can be stopped at position P21. When the analysis value of the inspection item A1 exceeds the upper limit value, the sample dispensing probe 16 is stopped at the first suction position P21 during the suction for analyzing the inspection items B2 to Bn other than the inspection item B1. Can be made. Thereby, contact between the sample and the portion unnecessary for suction of the outer wall of the sample dispensing probe 16 and the sample can be prevented, and contamination of the outer wall of the sample dispensing probe 16 can be suppressed.

  Further, when the analysis value of the inspection item A1 exceeds the upper limit value, the sample dispensing probe 16 is moved to the second suction position below the first suction position P21 during the suction for analyzing the inspection item B1. By stopping at P22, mixing of the inspection item A1 component into the upper layer sample sucked by the sample dispensing probe 16 can be prevented. Thereby, deterioration of the analysis data of inspection item B1 can be prevented.

  Although several embodiments of the present invention have been described, these embodiments are presented by way of example and are not intended to limit the scope of the invention. These novel embodiments can be implemented in various other forms, and various omissions, replacements, and changes can be made without departing from the scope of the invention. These embodiments and modifications thereof are included in the scope and gist of the invention, and are included in the invention described in the claims and the equivalents thereof.

D1 First distance D2 Second distance P21 First suction position P22 Second suction position 10 Sample dispensing arm 16 Sample dispensing probe 16a Liquid level detector 16b Sample dispensing pump 17 Sample container 110 Blood analyzer 120 Data storage device 161 tube

Claims (8)

In an automatic analyzer that dispenses a sample contained in a sample container and measures the mixture,
A dispensing probe for performing dispensing to suck and discharge the sample;
A detector for detecting the sample by contact between the sample and the dispensing probe;
A drive control unit that moves the dispensing probe based on an analysis value obtained by analyzing a predetermined component contained in the sample and a detection signal detected by the detector;
The drive control unit stops the dispensing probe at a first suction position below a first distance from a position in contact with the sample when the analysis value is less than or equal to a preset upper limit value. An automatic analyzer characterized by stopping the dispensing probe at a second suction position below the first suction position when a value exceeds the upper limit value. A plurality of inspection items to be inspected using the sample and an operation unit capable of inputting inspection items affected by the predetermined component of the inspection items,
When the analysis value exceeds the upper limit value, the drive control unit stops the dispensing probe at the second suction position at the time of suction for analyzing the affected examination item, 2. The automatic analyzer according to claim 1, wherein the dispensing probe is stopped at the first suction position at the time of suction for analyzing an inspection item other than the affected inspection item. The analysis value is obtained from an external analyzer that analyzes the predetermined component,
The sample used for analysis by the external analyzer is a test sample collected from a subject,
The automatic analyzer according to claim 1 or 2, wherein the sample sucked by the dispensing probe is an upper layer sample separated from the test sample. The sample used for the analysis of the predetermined component is blood;
The automatic analyzer according to any one of claims 1 to 3, wherein the sample sucked by the dispensing probe is serum separated from the blood.   3. The automatic analyzer according to claim 2, wherein the predetermined component is platelets contained in blood, and the test item affected is lactate dehydrogenase contained in serum separated from the serum. .   The automatic analyzer according to any one of claims 1 to 5, wherein the sample container is a blood collection tube. A cleaning unit for cleaning the dispensing probe;
The drive control unit stops the dispensing probe, which has finished dispensing the sample that has been aspirated only at the first aspiration position, at a first washing position where the washing unit can wash the sample. The dispensing probe that has finished dispensing of the sample that has been aspirated at the suction position of 2 is stopped at the second washing position where the washing unit can be washed below the first washing position. An automatic analyzer according to any one of claims 1 to 6, characterized in that: Data storage for storing analysis values obtained from an automatic analyzer that dispenses a sample contained in a sample container and measures the mixture, and an external analyzer that analyzes predetermined components contained in the sample An inspection system in which a device is connected by a network,
The automatic analyzer is
A dispensing probe for performing dispensing to suck and discharge the sample;
A detector for detecting the sample by contact between the sample and the dispensing probe;
A drive control unit that moves the dispensing probe based on the analysis value and a detection signal detected by the detector;
The drive control unit stops the dispensing probe at a first suction position below a first distance from a position in contact with the sample when the analysis value is less than or equal to a preset upper limit value. An inspection system characterized by stopping at a second suction position below the first suction position when the value exceeds the upper limit value.

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