JP2012532739A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2012532739A5 JP2012532739A5 JP2012520713A JP2012520713A JP2012532739A5 JP 2012532739 A5 JP2012532739 A5 JP 2012532739A5 JP 2012520713 A JP2012520713 A JP 2012520713A JP 2012520713 A JP2012520713 A JP 2012520713A JP 2012532739 A5 JP2012532739 A5 JP 2012532739A5
- Authority
- JP
- Japan
- Prior art keywords
- body member
- engineered
- nanoparticle body
- processed
- item
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000002105 nanoparticle Substances 0.000 claims description 53
- 239000002245 particle Substances 0.000 claims description 52
- 238000005096 rolling process Methods 0.000 claims description 12
- 239000003814 drug Substances 0.000 claims description 10
- 239000000203 mixture Substances 0.000 claims description 10
- 229940124597 therapeutic agent Drugs 0.000 claims description 7
- 239000000443 aerosol Substances 0.000 claims description 5
- 239000003795 chemical substances by application Substances 0.000 claims description 4
- 239000000463 material Substances 0.000 claims description 4
- -1 taggant Substances 0.000 claims description 4
- 239000002872 contrast media Substances 0.000 claims description 3
- 239000000032 diagnostic agent Substances 0.000 claims description 3
- 229940039227 diagnostic agent Drugs 0.000 claims description 3
- 239000003124 biologic agent Substances 0.000 claims description 2
- 210000003169 central nervous system Anatomy 0.000 claims description 2
- 229940079593 drug Drugs 0.000 claims description 2
- 239000000696 magnetic material Substances 0.000 claims description 2
- 239000002907 paramagnetic material Substances 0.000 claims description 2
- 238000005191 phase separation Methods 0.000 claims description 2
- 230000002685 pulmonary effect Effects 0.000 claims description 2
- 230000019491 signal transduction Effects 0.000 claims description 2
- 238000000034 method Methods 0.000 description 7
- 239000011344 liquid material Substances 0.000 description 3
- 239000000758 substrate Substances 0.000 description 2
- 102000004190 Enzymes Human genes 0.000 description 1
- 108090000790 Enzymes Proteins 0.000 description 1
- 239000003242 anti bacterial agent Substances 0.000 description 1
- 229940088710 antibiotic agent Drugs 0.000 description 1
- 239000002246 antineoplastic agent Substances 0.000 description 1
- 239000003443 antiviral agent Substances 0.000 description 1
- 239000002157 polynucleotide Substances 0.000 description 1
- 102000040430 polynucleotide Human genes 0.000 description 1
- 108091033319 polynucleotide Proteins 0.000 description 1
- 102000004196 processed proteins & peptides Human genes 0.000 description 1
- 108090000765 processed proteins & peptides Proteins 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 230000010076 replication Effects 0.000 description 1
- 150000003384 small molecules Chemical class 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 238000009736 wetting Methods 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US22513809P | 2009-07-13 | 2009-07-13 | |
| US61/225,138 | 2009-07-13 | ||
| PCT/US2010/041797 WO2011008737A2 (en) | 2009-07-13 | 2010-07-13 | Engineered aerosol particles, and associated methods |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014182213A Division JP6189807B2 (ja) | 2009-07-13 | 2014-09-08 | 工学的に作製されたエアロゾル粒子、およびそれに関連した方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2012532739A JP2012532739A (ja) | 2012-12-20 |
| JP2012532739A5 true JP2012532739A5 (enExample) | 2013-08-15 |
| JP5656996B2 JP5656996B2 (ja) | 2015-01-21 |
Family
ID=42818752
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012520713A Expired - Fee Related JP5656996B2 (ja) | 2009-07-13 | 2010-07-13 | 工学的に作製されたエアロゾル粒子、およびそれに関連した方法 |
| JP2014182213A Active JP6189807B2 (ja) | 2009-07-13 | 2014-09-08 | 工学的に作製されたエアロゾル粒子、およびそれに関連した方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014182213A Active JP6189807B2 (ja) | 2009-07-13 | 2014-09-08 | 工学的に作製されたエアロゾル粒子、およびそれに関連した方法 |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US20120114554A1 (enExample) |
| EP (1) | EP2454011A2 (enExample) |
| JP (2) | JP5656996B2 (enExample) |
| WO (1) | WO2011008737A2 (enExample) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9057712B1 (en) | 2011-10-27 | 2015-06-16 | Copilot Ventures Fund Iii Llc | Methods of delivery of encapsulated perfluorocarbon taggants |
| EP2785326A2 (en) * | 2011-11-29 | 2014-10-08 | The University of North Carolina at Chapel Hill | Geometrically engineered particles and methods for modulating macrophage or immune responses |
| WO2016172183A1 (en) * | 2015-04-21 | 2016-10-27 | Ran Biotechnologies, Inc. | Novel fluorinated surfactants |
| UY36851A (es) | 2015-08-16 | 2017-03-31 | Glaxosmithkline Ip Dev Ltd | Compuestos para uso en aplicaciones antibacterianas |
| AR106018A1 (es) | 2015-08-26 | 2017-12-06 | Achillion Pharmaceuticals Inc | Compuestos de arilo, heteroarilo y heterocíclicos para el tratamiento de trastornos médicos |
| WO2017035408A1 (en) | 2015-08-26 | 2017-03-02 | Achillion Pharmaceuticals, Inc. | Compounds for treatment of immune and inflammatory disorders |
| WO2017085692A1 (en) | 2015-11-18 | 2017-05-26 | Glaxosmithkline Intellectual Property (No.2) Limited | Pharmaceutical compositions of ribavirin |
| CN109039579A (zh) * | 2016-04-28 | 2018-12-18 | 王志 | 一种Lorenz型吸引子的简单混沌系统电路 |
| EP3452170A4 (en) | 2016-05-05 | 2020-04-01 | Liquidia Technologies, Inc. | TREPROSTINIL IN POWDER FORM FOR TREATING PULMONAL HYPERTENSION |
| CN121974842A (zh) | 2016-05-10 | 2026-05-05 | C4医药公司 | 用于靶蛋白降解的胺连接的c3-戊二酰亚胺降解决定子体 |
| MX2018016046A (es) | 2016-06-27 | 2019-05-02 | Achillion Pharmaceuticals Inc | Quinazolina y compuestos indol para tratar trastornos medicos. |
| CA3053818A1 (en) | 2017-03-01 | 2018-09-07 | Achillion Pharmaceuticals, Inc. | Aryl, heteroaryl, and heterocyclic pharmaceutical compounds for treatment of medical disorders |
| EP4717317A3 (en) | 2017-06-20 | 2026-06-03 | C4 Therapeutics, Inc. | N/o-linked degrons and degronimers for protein degradation |
| CN111902141A (zh) | 2018-03-26 | 2020-11-06 | C4医药公司 | 用于ikaros降解的羟脑苷脂结合剂 |
| EP3841086B1 (en) | 2018-08-20 | 2025-04-23 | Achillion Pharmaceuticals, Inc. | Pharmaceutical compounds for the treatment of complement factor d medical disorders |
| JP7443375B2 (ja) | 2018-09-06 | 2024-03-05 | アキリオン ファーマシューティカルズ， インコーポレーテッド | 医学的障害の治療のための大環状化合物 |
| CN113365617B (zh) | 2018-10-16 | 2025-12-23 | 乔治亚州立大学研究基金会股份有限公司 | 用于医学疾病治疗的一氧化碳前药 |
| MX2021011507A (es) | 2019-03-22 | 2021-12-15 | Achillion Pharmaceuticals Inc | Compuestos farmaceuticos para el tratamiento de trastornos mediados por complemento. |
| JP2023515073A (ja) | 2020-02-20 | 2023-04-12 | アキリオン ファーマシューティカルズ， インコーポレーテッド | 補体因子ｄ媒介障害の処置用のヘテロアリール化合物 |
| CN119823124A (zh) | 2020-03-05 | 2025-04-15 | C4医药公司 | 用于brd9的靶向降解的化合物 |
| CA3193488A1 (en) | 2020-09-23 | 2022-03-31 | Jason Allan Wiles | Pharmaceutical compounds for the treatment of complement mediated disorders |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5399363A (en) | 1991-01-25 | 1995-03-21 | Eastman Kodak Company | Surface modified anticancer nanoparticles |
| WO1994016758A1 (en) | 1991-03-05 | 1994-08-04 | Miris Medical Corporation | A medication cassette for an automatic aerosol medication delivery system |
| ES2141108T3 (es) | 1991-07-02 | 2000-03-16 | Inhale Inc | Metodo y dispositivo para proporcionar medicamentos en aerosol. |
| US5785049A (en) | 1994-09-21 | 1998-07-28 | Inhale Therapeutic Systems | Method and apparatus for dispersion of dry powder medicaments |
| US5934272A (en) | 1993-01-29 | 1999-08-10 | Aradigm Corporation | Device and method of creating aerosolized mist of respiratory drug |
| US5558085A (en) | 1993-01-29 | 1996-09-24 | Aradigm Corporation | Intrapulmonary delivery of peptide drugs |
| US5497763A (en) | 1993-05-21 | 1996-03-12 | Aradigm Corporation | Disposable package for intrapulmonary delivery of aerosolized formulations |
| ATE387925T1 (de) | 1994-09-21 | 2008-03-15 | Nektar Therapeutics | Vorrichtung und verfahren zum dispergieren von trockenen pulvermedikamenten |
| US5780014A (en) | 1995-04-14 | 1998-07-14 | Inhale Therapeutic Systems | Method and apparatus for pulmonary administration of dry powder alpha 1-antitrypsin |
| CN1890603B (zh) * | 2003-12-01 | 2011-07-13 | 伊利诺伊大学评议会 | 用于制造三维纳米级结构的方法和装置 |
| WO2005101466A2 (en) | 2003-12-19 | 2005-10-27 | The University Of North Carolina At Chapel Hill | Methods for fabricating isolated micro- and nano- structures using soft or imprint lithography |
| WO2007030698A2 (en) * | 2005-09-07 | 2007-03-15 | The University Of North Carolina At Chapel Hill | Materials and methods for fabricating isolated micro-and nano-structures having chemical functionality |
| WO2006130943A1 (en) * | 2005-06-10 | 2006-12-14 | The Governors Of The University Of Alberta | Respirable dried powder formulation comprising drug loaded nanoparticles |
| CA2611985C (en) * | 2005-06-17 | 2016-08-16 | The University Of North Carolina At Chapel Hill | Nanoparticle fabrication methods, systems, and materials |
| WO2007094829A2 (en) * | 2005-11-07 | 2007-08-23 | The University Of North Carolina At Chapel Hill | Isolated and fixed micro and nano structures and methods thereof |
| WO2008011051A1 (en) * | 2006-07-17 | 2008-01-24 | Liquidia Technologies, Inc. | Nanoparticle fabrication methods, systems, and materials |
| US20100055459A1 (en) * | 2006-08-30 | 2010-03-04 | Liquidia Technologies, Inc. | Nanoparticles Having Functional Additives for Self and Directed Assembly and Methods of Fabricating Same |
| US7875654B2 (en) * | 2007-03-23 | 2011-01-25 | The Board Of Trustees Of The University Of Illinois | System for forming janus particles |
-
2010
- 2010-07-13 US US13/383,518 patent/US20120114554A1/en not_active Abandoned
- 2010-07-13 JP JP2012520713A patent/JP5656996B2/ja not_active Expired - Fee Related
- 2010-07-13 WO PCT/US2010/041797 patent/WO2011008737A2/en not_active Ceased
- 2010-07-13 EP EP10742329A patent/EP2454011A2/en not_active Ceased
-
2014
- 2014-09-08 JP JP2014182213A patent/JP6189807B2/ja active Active
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Cojocaru et al. | Nanoparticle-based drug delivery systems in inhaled therapy: improving respiratory medicine | |
| JP6189807B2 (ja) | 工学的に作製されたエアロゾル粒子、およびそれに関連した方法 | |
| Malamatari et al. | Spray drying for the preparation of nanoparticle-based drug formulations as dry powders for inhalation | |
| Peng et al. | Nano-formulations for pulmonary delivery: Past, present, and future perspectives | |
| Heng et al. | The nano spray dryer B-90 | |
| Bakhtiary et al. | Microparticles containing erlotinib-loaded solid lipid nanoparticles for treatment of non-small cell lung cancer | |
| Kumar et al. | Nanomedicine in drug delivery | |
| Kelly et al. | Shape-specific, monodisperse nano-molding of protein particles | |
| Garello et al. | Micro/nanosystems for magnetic targeted delivery of bioagents | |
| ATE287257T1 (de) | Zubereitung von partikelhaltigen arzneimitteln zur inhalation | |
| Herzog et al. | Exposure of silver-nanoparticles and silver-ions to lung cells in vitro at the air-liquid interface | |
| CN108578372A (zh) | 微晶二酮哌嗪组合物以及方法 | |
| CN103393621A (zh) | 生产多层粒子、纤维和喷雾的系统和方法以及施用它们的方法 | |
| Dua et al. | Targeting microRNAs using nanotechnology in pulmonary diseases. | |
| Negi et al. | Engineering inhalable therapeutic particles: conventional and emerging approaches | |
| Tomoda et al. | Preparation and properties of inhalable nanocomposite particles: effects of the temperature at a spray-dryer inlet upon the properties of particles | |
| Sultana et al. | Inhalation of alendronate nanoparticles as dry powder inhaler for the treatment of osteoporosis | |
| Keil et al. | Evaluation of adsorption of DNA/PEI polyplexes to tubing materials | |
| Kwak et al. | Microfluidic platforms for ex vivo and in vivo gene therapy | |
| CN102365126B (zh) | 用于生产包覆粒子的工艺和设备 | |
| Pawara et al. | Spray dried nanoparticle for pulmonary delivery: current developments and future perspectives | |
| Dangova et al. | Nanocarriers-assisted nose-to-brain delivery of levodopa: current progress and prospects | |
| Donovan et al. | Novel dry powder inhaler particle-dispersion systems | |
| Raj et al. | Nanocarrier-enabled chemotherapy and diagnostics in respiratory diseases | |
| CN104116712B (zh) | 一种用于肺部给药的干扰素‑白蛋白中空性纳米聚集颗粒 |