JP5656996B2 - 工学的に作製されたエアロゾル粒子、およびそれに関連した方法 - Google Patents

工学的に作製されたエアロゾル粒子、およびそれに関連した方法 Download PDF

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Publication number
JP5656996B2
JP5656996B2 JP2012520713A JP2012520713A JP5656996B2 JP 5656996 B2 JP5656996 B2 JP 5656996B2 JP 2012520713 A JP2012520713 A JP 2012520713A JP 2012520713 A JP2012520713 A JP 2012520713A JP 5656996 B2 JP5656996 B2 JP 5656996B2
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particles
engineered
body member
particle
processed
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Japanese (ja)
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JP2012532739A5 (enExample
JP2012532739A (ja
Inventor
ジョセフ エム. デジモン,
ジョセフ エム. デジモン,
ベンジャミン メイナー,
ベンジャミン メイナー,
メアリー ネピアー,
メアリー ネピアー,
ジョナサン ピライ,
ジョナサン ピライ,
フィリップ デジモン,
フィリップ デジモン,
ウィル パトリック,
ウィル パトリック,
カイル レーカー,
カイル レーカー,
ハンジュン チャン,
ハンジュン チャン,
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University of North Carolina at Chapel Hill
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University of North Carolina at Chapel Hill
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    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2/00Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic
    • B01J2/22Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic by pressing in moulds or between rollers
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00Stock material or miscellaneous articles
    • Y10T428/29Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982Particulate matter [e.g., sphere, flake, etc.]

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Preparation (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
JP2012520713A 2009-07-13 2010-07-13 工学的に作製されたエアロゾル粒子、およびそれに関連した方法 Expired - Fee Related JP5656996B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US22513809P 2009-07-13 2009-07-13
US61/225,138 2009-07-13
PCT/US2010/041797 WO2011008737A2 (en) 2009-07-13 2010-07-13 Engineered aerosol particles, and associated methods

Related Child Applications (1)

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JP2014182213A Division JP6189807B2 (ja) 2009-07-13 2014-09-08 工学的に作製されたエアロゾル粒子、およびそれに関連した方法

Publications (3)

Publication Number Publication Date
JP2012532739A JP2012532739A (ja) 2012-12-20
JP2012532739A5 JP2012532739A5 (enExample) 2013-08-15
JP5656996B2 true JP5656996B2 (ja) 2015-01-21

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JP2012520713A Expired - Fee Related JP5656996B2 (ja) 2009-07-13 2010-07-13 工学的に作製されたエアロゾル粒子、およびそれに関連した方法
JP2014182213A Active JP6189807B2 (ja) 2009-07-13 2014-09-08 工学的に作製されたエアロゾル粒子、およびそれに関連した方法

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US (1) US20120114554A1 (enExample)
EP (1) EP2454011A2 (enExample)
JP (2) JP5656996B2 (enExample)
WO (1) WO2011008737A2 (enExample)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9057712B1 (en) 2011-10-27 2015-06-16 Copilot Ventures Fund Iii Llc Methods of delivery of encapsulated perfluorocarbon taggants
WO2013082111A2 (en) * 2011-11-29 2013-06-06 The University Of North Carolina At Chapel Hill Geometrically engineered particles and methods for modulating macrophage or immune responses
US11505648B2 (en) * 2015-04-21 2022-11-22 Ran Biotechnologies, Inc. Fluorinated surfactants
UY36851A (es) 2015-08-16 2017-03-31 Glaxosmithkline Ip Dev Ltd Compuestos para uso en aplicaciones antibacterianas
AR106018A1 (es) 2015-08-26 2017-12-06 Achillion Pharmaceuticals Inc Compuestos de arilo, heteroarilo y heterocíclicos para el tratamiento de trastornos médicos
EP3340982B1 (en) 2015-08-26 2021-12-15 Achillion Pharmaceuticals, Inc. Compounds for treatment of immune and inflammatory disorders
BR112018009899A8 (pt) 2015-11-18 2019-02-26 Glaxosmithkline Ip No 2 Ltd composição, inalador, forma de dosagem única, métodos para fabricar partículas, para melhorar as exacerbações induzidas por infecção respiratória de um distúrbio respiratório, para prevenir as exacerbações induzidas por infecção respiratória de um distúrbio respiratório, para reduzir a incidência das exacerbações induzidas por infecção respiratória de um distúrbio respiratório, para reduzir a gravidade das exacerbações induzidas por infecção respiratória de um distúrbio respiratório, para prevenir uma infecção respiratória viral e para fabricar uma partícula de inalação de pó seco de ribavirina controlada na forma polimorfa cristalina, partículas fabricadas, método de tratamento, pluralidade de partículas, e, recipiente de dose.
CN105790924B (zh) * 2016-04-28 2018-11-02 滁州博明信息科技有限公司 一种具有Lorenz型吸引子的简单混沌系统电路
IL262720B2 (en) 2016-05-05 2024-06-01 Liquidia Tech Inc Dry powder treprostinil for the treatment of pulmonary hypertension
EP3455219A4 (en) 2016-05-10 2019-12-18 C4 Therapeutics, Inc. AMINE-RELATED C3-GLUTARIMIDE DEGRONIMERS FOR TARGET PROTEIN REDUCTION
AU2017290593A1 (en) 2016-06-27 2019-01-03 Achillion Pharmaceuticals, Inc. Quinazoline and indole compounds to treat medical disorders
CN110603252A (zh) 2017-03-01 2019-12-20 艾其林医药公司 用于治疗医学障碍的芳基、杂芳基和杂环药物化合物
CN118440096A (zh) 2017-06-20 2024-08-06 C4医药公司 用于蛋白降解的n/o-连接的降解决定子和降解决定子体
KR20210018199A (ko) 2018-03-26 2021-02-17 씨4 테라퓨틱스, 인코포레이티드 이카로스의 분해를 위한 세레블론 결합제
WO2020041301A1 (en) 2018-08-20 2020-02-27 Achillion Pharmaceuticals, Inc. Pharmaceutical compounds for the treatment of complement factor d medical disorders
US11814391B2 (en) 2018-09-06 2023-11-14 Achillion Pharmaceuticals, Inc. Macrocyclic compounds for the treatment of medical disorders
WO2020081723A1 (en) 2018-10-16 2020-04-23 Georgia State University Research Foundation, Inc. Carbon monoxide prodrugs for the treatment of medical disorders
US20250197403A1 (en) 2020-02-20 2025-06-19 Achillion Pharmaceuticals, Inc. Heteroaryl compounds for treatment of complement factor d mediated disorders
AU2021231898A1 (en) 2020-03-05 2022-10-27 C4 Therapeutics, Inc. Compounds for targeted degradation of BRD9
CN116437913A (zh) 2020-09-23 2023-07-14 艾其林医药公司 用于治疗补体介导的病症的药物化合物

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5399363A (en) 1991-01-25 1995-03-21 Eastman Kodak Company Surface modified anticancer nanoparticles
AU6130594A (en) 1991-03-05 1994-08-15 Miris Medical Corporation Method and device for correcting the drift offset of a pressure sensor of a flowmeter
CA2112674C (en) 1991-07-02 2005-10-04 John S. Patton Method and device for delivering aerosolized medicaments
US5785049A (en) 1994-09-21 1998-07-28 Inhale Therapeutic Systems Method and apparatus for dispersion of dry powder medicaments
US5934272A (en) 1993-01-29 1999-08-10 Aradigm Corporation Device and method of creating aerosolized mist of respiratory drug
US5558085A (en) 1993-01-29 1996-09-24 Aradigm Corporation Intrapulmonary delivery of peptide drugs
US5497763A (en) 1993-05-21 1996-03-12 Aradigm Corporation Disposable package for intrapulmonary delivery of aerosolized formulations
CZ289029B6 (cs) 1994-09-21 2001-10-17 Inhale Therapeutic Systems Způsob aerosolizace práąku, zejména práąkového léku a zařízení k provádění tohoto způsobu
US5780014A (en) 1995-04-14 1998-07-14 Inhale Therapeutic Systems Method and apparatus for pulmonary administration of dry powder alpha 1-antitrypsin
US7704684B2 (en) * 2003-12-01 2010-04-27 The Board Of Trustees Of The University Of Illinois Methods and devices for fabricating three-dimensional nanoscale structures
KR101281775B1 (ko) 2003-12-19 2013-07-15 더 유니버시티 오브 노쓰 캐롤라이나 엣 채플 힐 소프트 또는 임프린트 리소그래피를 이용하여 분리된마이크로- 및 나노- 구조를 제작하는 방법
WO2007030698A2 (en) * 2005-09-07 2007-03-15 The University Of North Carolina At Chapel Hill Materials and methods for fabricating isolated micro-and nano-structures having chemical functionality
WO2006130943A1 (en) * 2005-06-10 2006-12-14 The Governors Of The University Of Alberta Respirable dried powder formulation comprising drug loaded nanoparticles
AU2006282042B2 (en) * 2005-06-17 2011-12-22 The University Of North Carolina At Chapel Hill Nanoparticle fabrication methods, systems, and materials
EP1951202A4 (en) * 2005-11-07 2013-03-06 Univ North Carolina ISOLATED AND SOLID MICRO AND NANO STRUCTURES AND METHOD THEREFOR
WO2008011051A1 (en) * 2006-07-17 2008-01-24 Liquidia Technologies, Inc. Nanoparticle fabrication methods, systems, and materials
US20100055459A1 (en) * 2006-08-30 2010-03-04 Liquidia Technologies, Inc. Nanoparticles Having Functional Additives for Self and Directed Assembly and Methods of Fabricating Same
US7875654B2 (en) * 2007-03-23 2011-01-25 The Board Of Trustees Of The University Of Illinois System for forming janus particles

Also Published As

Publication number Publication date
WO2011008737A3 (en) 2011-06-23
WO2011008737A8 (en) 2011-08-11
EP2454011A2 (en) 2012-05-23
US20120114554A1 (en) 2012-05-10
JP2015027504A (ja) 2015-02-12
JP6189807B2 (ja) 2017-08-30
WO2011008737A2 (en) 2011-01-20
JP2012532739A (ja) 2012-12-20

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