JP2012531205A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2012531205A5 JP2012531205A5 JP2012517731A JP2012517731A JP2012531205A5 JP 2012531205 A5 JP2012531205 A5 JP 2012531205A5 JP 2012517731 A JP2012517731 A JP 2012517731A JP 2012517731 A JP2012517731 A JP 2012517731A JP 2012531205 A5 JP2012531205 A5 JP 2012531205A5
- Authority
- JP
- Japan
- Prior art keywords
- influenza virus
- polypeptide
- recombinant
- amino acid
- reassortant
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 241000712461 unidentified influenza virus Species 0.000 claims 41
- 229920001184 polypeptide Polymers 0.000 claims 26
- 102000004196 processed proteins & peptides Human genes 0.000 claims 26
- 108090000765 processed proteins & peptides Proteins 0.000 claims 26
- 125000003275 alpha amino acid group Chemical group 0.000 claims 22
- 102000005348 Neuraminidase Human genes 0.000 claims 10
- 108010006232 Neuraminidase Proteins 0.000 claims 10
- 238000000034 method Methods 0.000 claims 8
- 238000006467 substitution reaction Methods 0.000 claims 8
- 102000039446 nucleic acids Human genes 0.000 claims 7
- 108020004707 nucleic acids Proteins 0.000 claims 7
- 150000007523 nucleic acids Chemical class 0.000 claims 7
- 239000000203 mixture Substances 0.000 claims 6
- 241000700605 Viruses Species 0.000 claims 3
- 230000002238 attenuated effect Effects 0.000 claims 3
- 230000002163 immunogen Effects 0.000 claims 3
- 206010022000 influenza Diseases 0.000 claims 3
- 229960003971 influenza vaccine Drugs 0.000 claims 3
- 239000002773 nucleotide Substances 0.000 claims 2
- 125000003729 nucleotide group Chemical group 0.000 claims 2
- 239000013598 vector Substances 0.000 claims 2
- 241000725681 Swine influenza virus Species 0.000 claims 1
- 230000006978 adaptation Effects 0.000 claims 1
- 238000004113 cell culture Methods 0.000 claims 1
- 238000012258 culturing Methods 0.000 claims 1
- 238000009472 formulation Methods 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 230000010076 replication Effects 0.000 claims 1
- 230000035945 sensitivity Effects 0.000 claims 1
- 229960005486 vaccine Drugs 0.000 claims 1
Applications Claiming Priority (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US22042609P | 2009-06-25 | 2009-06-25 | |
| US61/220,426 | 2009-06-25 | ||
| US22798609P | 2009-07-23 | 2009-07-23 | |
| US61/227,986 | 2009-07-23 | ||
| US23402109P | 2009-08-14 | 2009-08-14 | |
| US61/234,021 | 2009-08-14 | ||
| US25889009P | 2009-11-06 | 2009-11-06 | |
| US61/258,890 | 2009-11-06 | ||
| PCT/US2010/039826 WO2010151673A1 (en) | 2009-06-25 | 2010-06-24 | Swine influenza hemagglutinin variants |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2012531205A JP2012531205A (ja) | 2012-12-10 |
| JP2012531205A5 true JP2012531205A5 (https=) | 2013-06-13 |
| JP5745511B2 JP5745511B2 (ja) | 2015-07-08 |
Family
ID=43386887
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012517731A Expired - Fee Related JP5745511B2 (ja) | 2009-06-25 | 2010-06-24 | ブタインフルエンザヘマグルチニン変異体 |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US8088393B2 (https=) |
| EP (1) | EP2448598B1 (https=) |
| JP (1) | JP5745511B2 (https=) |
| KR (1) | KR20120101318A (https=) |
| CN (1) | CN102802666B (https=) |
| AU (2) | AU2010266078B2 (https=) |
| BR (1) | BRPI1014844A2 (https=) |
| CA (1) | CA2766377A1 (https=) |
| MX (1) | MX2012000123A (https=) |
| NZ (2) | NZ617191A (https=) |
| RU (1) | RU2560420C2 (https=) |
| SG (2) | SG176178A1 (https=) |
| WO (1) | WO2010151673A1 (https=) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BRPI1014844A2 (pt) | 2009-06-25 | 2019-09-24 | Medimmune Llc | variantes de hemaglutinina de influenza suína. |
| US9017694B2 (en) * | 2011-10-07 | 2015-04-28 | Medimmune, Llc | Swine influenza hemagglutinin variants |
| KR101315273B1 (ko) * | 2012-10-29 | 2013-10-08 | 대한민국 | 강독화된 인플루엔자 바이러스 변이주 |
| KR20150110494A (ko) | 2012-12-03 | 2015-10-02 | 노파르티스 아게 | 재배열 인플루엔자 a 바이러스 |
| ES2833230T3 (es) * | 2014-05-13 | 2021-06-14 | Univ Pennsylvania | Composiciones que comprenden AVV que expresan construcciones y usos de doble anticuerpo del mismo |
| US9616114B1 (en) | 2014-09-18 | 2017-04-11 | David Gordon Bermudes | Modified bacteria having improved pharmacokinetics and tumor colonization enhancing antitumor activity |
| US10676723B2 (en) | 2015-05-11 | 2020-06-09 | David Gordon Bermudes | Chimeric protein toxins for expression by therapeutic bacteria |
| EA201792500A1 (ru) | 2015-05-13 | 2018-04-30 | Дзе Трастиз Оф Дзе Юниверсити Оф Пенсильвания | Aav-опосредованная экспрессия антител против гриппа и способы их использования |
| US11129906B1 (en) | 2016-12-07 | 2021-09-28 | David Gordon Bermudes | Chimeric protein toxins for expression by therapeutic bacteria |
| US11180535B1 (en) | 2016-12-07 | 2021-11-23 | David Gordon Bermudes | Saccharide binding, tumor penetration, and cytotoxic antitumor chimeric peptides from therapeutic bacteria |
| PT3589730T (pt) | 2017-02-28 | 2024-02-28 | Univ Pennsylvania | Vetor de vírus adenoassociado (aav) de clado f e suas utilizações |
| JOP20190200A1 (ar) | 2017-02-28 | 2019-08-27 | Univ Pennsylvania | تركيبات نافعة في معالجة ضمور العضل النخاعي |
| UY37620A (es) | 2017-02-28 | 2018-08-31 | Univ Pennsylvania | Vacunas contra la gripe mediadas por aav novedosas |
| US12178869B2 (en) | 2017-12-22 | 2024-12-31 | Codagenix Inc. | Recombinant virus with codon-pair deoptimized region and uses thereof for the treatment of cancer |
| WO2019172982A1 (en) | 2018-03-08 | 2019-09-12 | Codagenix Inc. | Attenuated flaviviruses |
| WO2025081053A1 (en) * | 2023-10-11 | 2025-04-17 | Flugen, Inc. | Formulations for thermostable vaccines |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7871626B2 (en) * | 2005-08-04 | 2011-01-18 | St. Jude Children's Research Hospital | Modified influenza virus for monitoring and improving vaccine efficiency |
| EP1945778B1 (en) * | 2005-10-17 | 2012-12-26 | MedImmune, LLC | Methods of increasing influenza virus replication |
| CN104140958A (zh) * | 2006-08-09 | 2014-11-12 | 米迪缪尼有限公司 | 流感血凝素和神经氨酸酶变体 |
| EP2160198A2 (en) * | 2007-05-31 | 2010-03-10 | Statens Serum Institut | Influenza vaccines |
| BRPI1014844A2 (pt) | 2009-06-25 | 2019-09-24 | Medimmune Llc | variantes de hemaglutinina de influenza suína. |
-
2010
- 2010-06-24 BR BRPI1014844-2A patent/BRPI1014844A2/pt not_active IP Right Cessation
- 2010-06-24 EP EP10792667.7A patent/EP2448598B1/en not_active Not-in-force
- 2010-06-24 CN CN201080027726.4A patent/CN102802666B/zh not_active Expired - Fee Related
- 2010-06-24 NZ NZ617191A patent/NZ617191A/en not_active IP Right Cessation
- 2010-06-24 NZ NZ596823A patent/NZ596823A/xx not_active IP Right Cessation
- 2010-06-24 CA CA2766377A patent/CA2766377A1/en not_active Abandoned
- 2010-06-24 SG SG2011085669A patent/SG176178A1/en unknown
- 2010-06-24 WO PCT/US2010/039826 patent/WO2010151673A1/en not_active Ceased
- 2010-06-24 KR KR1020127000803A patent/KR20120101318A/ko not_active Ceased
- 2010-06-24 RU RU2012102385/10A patent/RU2560420C2/ru not_active IP Right Cessation
- 2010-06-24 AU AU2010266078A patent/AU2010266078B2/en not_active Ceased
- 2010-06-24 MX MX2012000123A patent/MX2012000123A/es not_active Application Discontinuation
- 2010-06-24 US US12/822,781 patent/US8088393B2/en not_active Expired - Fee Related
- 2010-06-24 SG SG10201403557QA patent/SG10201403557QA/en unknown
- 2010-06-24 JP JP2012517731A patent/JP5745511B2/ja not_active Expired - Fee Related
-
2011
- 2011-12-01 US US13/308,809 patent/US8715691B2/en not_active Expired - Fee Related
-
2014
- 2014-06-25 AU AU2014203458A patent/AU2014203458A1/en not_active Abandoned
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2012531205A5 (https=) | ||
| RU2012102385A (ru) | Варианты гемагглютининов вируса свиного гриппа | |
| Begum et al. | Challenges and prospects of COVID‐19 vaccine development based on the progress made in SARS and MERS vaccine development | |
| Westgeest et al. | Genomewide analysis of reassortment and evolution of human influenza A (H3N2) viruses circulating between 1968 and 2011 | |
| KR100632429B1 (ko) | 프라이머 특이성 유무에 의한 멀티플렉스 역전사 중합효소연쇄반응을 이용한 재조합 독감 바이러스의 스크리닝 방법 | |
| Yang et al. | Human infection from avian-like influenza A (H1N1) viruses in pigs, China | |
| RU2011104999A (ru) | Варианты гемагглютинина и нейрамидазы вируса гриппа | |
| Tewawong et al. | Molecular epidemiology and phylogenetic analyses of influenza B virus in Thailand during 2010 to 2014 | |
| Fan et al. | Generation of live attenuated influenza virus by using codon usage bias | |
| Evseev et al. | Molecular evolution of the influenza A virus non-structural protein 1 in interspecies transmission and adaptation | |
| Jang et al. | Principles underlying rational design of live attenuated influenza vaccines | |
| JP2008522621A (ja) | 世界的に流行するトリインフルエンザに対して迅速に応答するためのワクチン | |
| Rash et al. | An efficient genome sequencing method for equine influenza [H3N8] virus reveals a new polymorphism in the PA-X protein | |
| Pohuang et al. | Sequence analysis of S1 genes of infectious bronchitis virus isolated in Thailand during 2008–2009: identification of natural recombination in the field isolates | |
| Swati et al. | Isolation and phylogenetic characterization of Canine distemper virus from India | |
| Shi et al. | Single immunization with Newcastle disease virus-vectored H7N9 vaccine confers a complete protection against challenge with highly pathogenic avian influenza H7N9 virus | |
| EP2716752A1 (en) | Canine influenza recombinant virus, preparation method therefor and application thereof | |
| RU2011137404A (ru) | Варианты гемагглютинина и нейраминидазы гриппа | |
| Zhou et al. | One HA stalk topping multiple heads as a novel influenza vaccine | |
| CN102600466B (zh) | 抗甲型流感病毒新型通用表位疫苗及其制备方法 | |
| JP2012517239A5 (https=) | ||
| Yi et al. | Molecular characterization of a virulent genotype VIId strain of Newcastle disease virus from farmed chickens in Shanghai | |
| Rovaris et al. | Phylogenetic analyses of the hemagglutinin gene of wild-type strains of canine distemper virus in southern Brazil | |
| Milani et al. | Vaccine immune pressure influences viral population complexity of avian influenza virus during infection | |
| CN103923886A (zh) | 流感病毒温度敏感株关键位点的筛选、突变株及其机制的探讨 |