JP2012530568A5 - - Google Patents
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- Publication number
- JP2012530568A5 JP2012530568A5 JP2012516553A JP2012516553A JP2012530568A5 JP 2012530568 A5 JP2012530568 A5 JP 2012530568A5 JP 2012516553 A JP2012516553 A JP 2012516553A JP 2012516553 A JP2012516553 A JP 2012516553A JP 2012530568 A5 JP2012530568 A5 JP 2012530568A5
- Authority
- JP
- Japan
- Prior art keywords
- hap
- cap
- bone substitute
- bone
- substitute material
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000463 material Substances 0.000 claims 13
- 239000000316 bone substitute Substances 0.000 claims 11
- 239000011162 core material Substances 0.000 claims 7
- 210000000988 bone and bone Anatomy 0.000 claims 4
- 238000000034 method Methods 0.000 claims 4
- 239000002159 nanocrystal Substances 0.000 claims 4
- 239000007864 aqueous solution Substances 0.000 claims 3
- 238000006243 chemical reaction Methods 0.000 claims 3
- 229910052588 hydroxylapatite Inorganic materials 0.000 claims 2
- XYJRXVWERLGGKC-UHFFFAOYSA-D pentacalcium;hydroxide;triphosphate Chemical compound [OH-].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O XYJRXVWERLGGKC-UHFFFAOYSA-D 0.000 claims 2
- 150000003839 salts Chemical class 0.000 claims 2
- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 claims 2
- 241001465754 Metazoa Species 0.000 claims 1
- 230000002051 biphasic effect Effects 0.000 claims 1
- 230000010478 bone regeneration Effects 0.000 claims 1
- 229910000389 calcium phosphate Inorganic materials 0.000 claims 1
- 239000001506 calcium phosphate Substances 0.000 claims 1
- 235000011010 calcium phosphates Nutrition 0.000 claims 1
- 239000011248 coating agent Substances 0.000 claims 1
- 238000000576 coating method Methods 0.000 claims 1
- 230000007547 defect Effects 0.000 claims 1
- 239000010419 fine particle Substances 0.000 claims 1
- 239000008187 granular material Substances 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 230000011164 ossification Effects 0.000 claims 1
- 238000002791 soaking Methods 0.000 claims 1
- 239000011343 solid material Substances 0.000 claims 1
- 230000001954 sterilising effect Effects 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP09008201 | 2009-06-23 | ||
| EP09008201.7 | 2009-06-23 | ||
| PCT/EP2010/003590 WO2010149296A1 (en) | 2009-06-23 | 2010-06-15 | Bone substitute material |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2012530568A JP2012530568A (ja) | 2012-12-06 |
| JP2012530568A5 true JP2012530568A5 (cg-RX-API-DMAC7.html) | 2013-07-04 |
| JP5778139B2 JP5778139B2 (ja) | 2015-09-16 |
Family
ID=41137892
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012516553A Active JP5778139B2 (ja) | 2009-06-23 | 2010-06-15 | 骨代用材料 |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US8734524B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP2445543B1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP5778139B2 (cg-RX-API-DMAC7.html) |
| KR (1) | KR101558856B1 (cg-RX-API-DMAC7.html) |
| CN (1) | CN102497891B (cg-RX-API-DMAC7.html) |
| AU (1) | AU2010265114B2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2766663C (cg-RX-API-DMAC7.html) |
| DK (1) | DK2445543T3 (cg-RX-API-DMAC7.html) |
| ES (1) | ES2402961T3 (cg-RX-API-DMAC7.html) |
| PL (1) | PL2445543T3 (cg-RX-API-DMAC7.html) |
| PT (1) | PT2445543E (cg-RX-API-DMAC7.html) |
| RU (1) | RU2529802C2 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2010149296A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101599245B1 (ko) * | 2010-12-22 | 2016-03-03 | 가이스틀리히 파마 아게 | 골 대체 물질 |
| NL2011195C2 (en) | 2013-07-18 | 2015-01-21 | Xpand Biotechnology B V | Method for producing an osteoinductive calcium phosphate and products thus obtained. |
| EP2826495A1 (en) * | 2013-07-19 | 2015-01-21 | Geistlich Pharma AG | Biomimetic collagen-hydroxyapatite composite material |
| TWI783093B (zh) * | 2017-12-14 | 2022-11-11 | 瑞士商蓋茲特利製藥公司 | 骨替代材料及其製備及應用 |
| CN111465418B (zh) * | 2017-12-14 | 2021-07-09 | 盖斯特里希医药公司 | 骨替代材料 |
| RU2700770C2 (ru) * | 2018-02-13 | 2019-09-20 | Федеральное государственное бюджетное учреждение науки Институт металлургии и материаловедения им. А.А. Байкова Российской академии наук, ИМЕТ РАН | Способ изготовления матриксов на основе низкотемпературных модификаций фосфатов кальция для костной инженерии |
| WO2020249714A1 (en) * | 2019-06-14 | 2020-12-17 | Geistlich Pharma Ag | Collagen matrix or granulate blend of bone substitute material |
| CN114761048B (zh) * | 2019-06-14 | 2023-05-02 | 盖斯特里希医药公司 | 骨替代材料的胶原基质或颗粒共混物 |
| CN110261418B (zh) * | 2019-07-12 | 2022-06-24 | 上海交通大学 | 精确测定羟基磷灰石中β-磷酸三钙的含量的方法 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3711426A1 (de) * | 1987-04-04 | 1988-10-13 | Mtu Muenchen Gmbh | Implantat mit bioaktivem ueberzug |
| GB8813033D0 (en) | 1988-06-02 | 1988-07-06 | Geistlich Soehne Ag | Chemical compound |
| JP2978203B2 (ja) * | 1990-04-20 | 1999-11-15 | 日本特殊陶業株式会社 | 生体活性な表面層を有するセラミックス体の製造方法 |
| US5676976A (en) * | 1995-05-19 | 1997-10-14 | Etex Corporation | Synthesis of reactive amorphous calcium phosphates |
| IT1288038B1 (it) * | 1996-04-30 | 1998-09-10 | Flametal S P A | Procedimento per la preparazione di rivestimenti di idrossiapatite |
| US6338752B1 (en) | 2000-04-20 | 2002-01-15 | Purzer Pharmaceutical Co., Ltd. | α-TCP/HAP biphasic cement and its preparing process |
| CN1241879C (zh) | 2004-04-13 | 2006-02-15 | 清华大学 | 磷酸钙陶瓷表面形成类骨磷灰石层的方法 |
-
2010
- 2010-06-15 RU RU2012101941/15A patent/RU2529802C2/ru active
- 2010-06-15 US US13/378,867 patent/US8734524B2/en active Active
- 2010-06-15 ES ES10726905T patent/ES2402961T3/es active Active
- 2010-06-15 CN CN201080037581.6A patent/CN102497891B/zh active Active
- 2010-06-15 CA CA2766663A patent/CA2766663C/en active Active
- 2010-06-15 PL PL10726905T patent/PL2445543T3/pl unknown
- 2010-06-15 KR KR1020127001162A patent/KR101558856B1/ko active Active
- 2010-06-15 WO PCT/EP2010/003590 patent/WO2010149296A1/en not_active Ceased
- 2010-06-15 AU AU2010265114A patent/AU2010265114B2/en not_active Ceased
- 2010-06-15 DK DK10726905.2T patent/DK2445543T3/da active
- 2010-06-15 PT PT107269052T patent/PT2445543E/pt unknown
- 2010-06-15 JP JP2012516553A patent/JP5778139B2/ja active Active
- 2010-06-15 EP EP10726905A patent/EP2445543B1/en active Active
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