JP2012530510A5 - - Google Patents
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- Publication number
- JP2012530510A5 JP2012530510A5 JP2012516777A JP2012516777A JP2012530510A5 JP 2012530510 A5 JP2012530510 A5 JP 2012530510A5 JP 2012516777 A JP2012516777 A JP 2012516777A JP 2012516777 A JP2012516777 A JP 2012516777A JP 2012530510 A5 JP2012530510 A5 JP 2012530510A5
- Authority
- JP
- Japan
- Prior art keywords
- fusion protein
- amino acid
- acid residues
- endolysin
- gram
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP09163955 | 2009-06-26 | ||
| EP09163955.9 | 2009-06-26 | ||
| PCT/EP2010/059152 WO2010149795A1 (en) | 2009-06-26 | 2010-06-28 | Antimicrobial agents |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016131194A Division JP2017018092A (ja) | 2009-06-26 | 2016-07-01 | 抗微生物剤 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2012530510A JP2012530510A (ja) | 2012-12-06 |
| JP2012530510A5 true JP2012530510A5 (https=) | 2013-08-15 |
| JP6034188B2 JP6034188B2 (ja) | 2016-11-30 |
Family
ID=42537604
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012516777A Active JP6034188B2 (ja) | 2009-06-26 | 2010-06-28 | 抗微生物剤 |
| JP2016131194A Pending JP2017018092A (ja) | 2009-06-26 | 2016-07-01 | 抗微生物剤 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016131194A Pending JP2017018092A (ja) | 2009-06-26 | 2016-07-01 | 抗微生物剤 |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US20120195872A1 (https=) |
| EP (2) | EP2446028B1 (https=) |
| JP (2) | JP6034188B2 (https=) |
| KR (1) | KR101701890B1 (https=) |
| CN (1) | CN102482655B (https=) |
| AU (1) | AU2010264659B2 (https=) |
| BR (1) | BRPI1015203B1 (https=) |
| CA (1) | CA2765810C (https=) |
| EA (1) | EA038542B1 (https=) |
| IL (1) | IL217121B (https=) |
| MX (1) | MX2011013453A (https=) |
| SG (1) | SG177704A1 (https=) |
| WO (1) | WO2010149795A1 (https=) |
Families Citing this family (50)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2010264659B2 (en) | 2009-06-26 | 2016-08-04 | Lysando Aktiengesellschaft | Antimicrobial agents |
| PL2445515T3 (pl) | 2009-06-26 | 2016-10-31 | Środki przeciwdrobnoustrojowe | |
| KR20120059576A (ko) | 2009-08-24 | 2012-06-08 | 뤼산도 홀딩 아게 | 신규한 엔도리신 ＯＢＰｇｐＬＹＳ |
| CA3048783C (en) | 2010-09-17 | 2022-05-24 | Tecnifar-Industria Tecnica Farmaceutica, S.A. | Antibacterial phage, phage peptides and methods of use thereof |
| EP2468856A1 (en) * | 2010-12-23 | 2012-06-27 | Lysando Aktiengesellschaft | Antimicrobial Agents |
| CN102766196B (zh) * | 2011-05-06 | 2014-10-29 | 上海医药工业研究院 | 一组阳离子抗菌肽及其制备方法和应用 |
| CN103361341B (zh) * | 2012-03-26 | 2015-09-02 | 复旦大学附属华山医院 | 杀菌肽ll-37的基因工程的表达及其制备方法和用途 |
| EP2679232A1 (en) * | 2012-06-29 | 2014-01-01 | Lysando Aktiengesellschaft | Composition for use in Mycobacteria vaccination |
| EP2679677A1 (en) * | 2012-06-29 | 2014-01-01 | Lysando Aktiengesellschaft | Composition for use in Mycobacteria therapy |
| US9388400B2 (en) | 2012-06-29 | 2016-07-12 | Lysando Ag | Composition for use in mycobacteria diagnosis |
| WO2015020765A2 (en) * | 2013-08-06 | 2015-02-12 | Trustees Of Dartmouth College | Unglycosylated lysostaphin variant protein |
| WO2015070911A1 (en) | 2013-11-14 | 2015-05-21 | Lysando Ag | Modified kz144 endolysin sequence |
| WO2015070912A1 (en) | 2013-11-14 | 2015-05-21 | Lysando Ag | Modified el188 endolysin sequence |
| EP2904912A1 (en) * | 2014-02-07 | 2015-08-12 | Hyglos Invest GmbH | Novel high pressure method with endolysin for processing of foods |
| EP3105322B1 (en) | 2014-02-14 | 2018-12-12 | Lysando AG | Antimicrobial agents |
| WO2016029920A1 (en) * | 2014-08-29 | 2016-03-03 | Aarhus Universitet | Positively charged co-polymers for use as antimicrobial agents |
| WO2016130024A1 (en) * | 2015-02-13 | 2016-08-18 | Supreme Biotechnologies Limited | Endolysin expression platform |
| CA3022334A1 (en) * | 2016-04-28 | 2017-11-02 | Lysando Ag | Antimicrobial agents against salmonella bacteria |
| EA201990856A1 (ru) * | 2016-10-20 | 2019-10-31 | Новые противомикробные агенты против бактерий enterococcus | |
| MX2019011808A (es) * | 2017-04-03 | 2020-01-09 | Sasinapas Co Ltd | Endolisinas de gram-negativas modificadas. |
| CN108018271B (zh) * | 2018-01-31 | 2020-08-11 | 武汉核圣生物技术有限公司 | 单亚基rna聚合酶、其纯化方法及在rna合成中的应用 |
| WO2019191633A2 (en) * | 2018-03-29 | 2019-10-03 | Contrafect Corporation | Lysin-antimicrobial peptide (amp) polypeptide constructs, lysins, isolated polynucleotides encoding same and uses thereof |
| AU2019276253A1 (en) * | 2018-05-30 | 2020-11-26 | Lysando Ag | Novel antimicrobial proteins |
| EP3840771A4 (en) * | 2018-08-23 | 2023-04-19 | Contrafect Corporation | Lysin-antimicrobial peptide (amp) polypeptide constructs, lysins, isolated polynucleotides encoding same and uses thereof |
| US12516309B2 (en) * | 2019-10-31 | 2026-01-06 | University Of Maryland, College Park | Method of treating infections by bacteriolytic enzymes and manufacture thereof |
| WO2021175606A1 (en) * | 2020-03-02 | 2021-09-10 | Unilever Ip Holdings B.V. | An effective anti-acne personal care composition |
| CA3171721A1 (en) | 2020-03-19 | 2021-09-23 | Fritz Eichenseher | A stabilized protein of interest |
| WO2022166736A1 (zh) | 2021-02-08 | 2022-08-11 | 武汉乐斯吉生物科技有限公司 | 噬菌体裂解酶、其嵌合物及应用 |
| WO2022225267A1 (ko) * | 2021-04-19 | 2022-10-27 | 엠브릭스 주식회사 | 보툴리늄 독소 전위 도메인 및 엔도라이신을 포함하는 단백질 복합체 및 이를 포함하는 항균 조성물 |
| CN119183372A (zh) * | 2022-03-03 | 2024-12-24 | 麻省理工学院 | 特异性靶向痤疮丙酸杆菌的细胞壁结合蛋白 |
| CN114540385B (zh) * | 2022-03-21 | 2023-06-23 | 齐鲁工业大学 | 一种利用大肠杆菌产溶葡萄球菌酶的方法 |
| CN114349870B (zh) * | 2022-03-21 | 2022-06-03 | 天津辅元生物医药科技有限公司 | 一种兼具防粘连功效的重组抗菌肽及其制备方法和应用 |
| WO2024241070A1 (en) | 2023-05-22 | 2024-11-28 | L'oreal | Cosmetic composition comprising an endolysin and a polyvinyl alcohol |
| FR3152395A1 (fr) | 2023-08-28 | 2025-03-07 | L'oreal | Composition cosmétique comprenant une endolysine dérivée de phage de Staphylococcus aureus et la 4-hydroxyacetophenone |
| FR3149207B1 (fr) | 2023-06-02 | 2026-03-13 | Oreal | Composition cosmétique comprenant une endolysine et un composé de formule (I) |
| FR3149205B1 (fr) | 2023-06-02 | 2026-04-24 | Loreal | Composition cosmétique comprenant une endolysine et un agent de charge organique |
| FR3149203B1 (fr) | 2023-06-02 | 2026-03-13 | Oreal | Composition anhydre comprenant une endolysine et de l’hydroxypropylmethylcellulose et/ou du pullulane |
| EP4719330A1 (en) | 2023-06-02 | 2026-04-08 | L'oreal | Cosmetic composition comprising an endolysin derived from a staphylococcus aureus phage and an aromatic alcohol |
| FR3149206B1 (fr) | 2023-06-02 | 2026-03-13 | Oreal | Composition cosmétique aqueuse comprenant une endolysine et du tréhalose |
| FR3149209B1 (fr) | 2023-06-02 | 2026-04-03 | Oreal | Composition cosmétique comprenant une endolysine dérivée de phage de Staphylococcus aureus et un alcool aromatique |
| FR3149208B1 (fr) | 2023-06-02 | 2026-03-20 | Oreal | Composition cosmétique, notamment aqueuse, comprenant une endolysine et un pullulane |
| FR3149204B1 (fr) | 2023-06-02 | 2026-02-13 | Oreal | Composition cosmétique comprenant une endolysine et un tensioactif non ionique comprenant un résidu carbohydrate |
| FR3149202B1 (fr) | 2023-06-02 | 2026-04-10 | Oreal | Composition cosmétique comprenant une endolysine dérivée de phage de Staphylococcus aureus et une huile. |
| FR3152394B1 (fr) | 2023-08-28 | 2026-04-24 | Loreal | Composition cosmétique comprenant une endolysine et des particules d’aérogel de silice hydrophobe |
| FR3152393B1 (fr) | 2023-08-28 | 2026-04-24 | Loreal | Composition cosmétique comprenant une endolysine dérivée d’un phage de Staphylococcus aureus et une charge minérale |
| FR3152396A1 (fr) | 2023-08-28 | 2025-03-07 | L'oreal | Composition cosmétique comprenant une endolysine dérivée de phage de Staphylococcus aureus et un polyhydroxyalcane |
| WO2025093666A1 (en) | 2023-11-01 | 2025-05-08 | University Of Copenhagen | Treatment of lymphoma |
| CN118421604B (zh) * | 2024-05-27 | 2024-10-22 | 小白鲸(中山)生物医药有限公司 | 一种重组溶葡萄球菌酶突变体及其制备方法和应用 |
| WO2026052743A1 (en) | 2024-09-04 | 2026-03-12 | Micreos Human Health B.V. | Reduction of trans-epidermal water loss by a polypeptide with antibacterial properties |
| CN119799685B (zh) * | 2024-12-27 | 2026-02-17 | 深圳先进技术研究院 | 一种靶向闪烁梭菌的抗菌蛋白及其制备方法与应用 |
Family Cites Families (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR970006154B1 (ko) | 1987-07-06 | 1997-04-24 | 루이지아나 스테이트 유니버시티 아그리컬춰럴 앤드 메카니칼 컬리지 | 용해성 펩티드에 의한 진핵 병원체와 신생물의 억제 및 섬유아세포와 임파구의 자극 |
| GB8816693D0 (en) | 1988-07-13 | 1988-08-17 | Agricultural & Food Res | Viral enzyme & gene |
| GB2255561B (en) | 1991-04-20 | 1995-06-21 | Agricultural & Food Res | Lysins from bacteriophages |
| EP0656952B1 (en) | 1992-08-21 | 2003-03-05 | The University Of British Columbia | Cationic peptides and method for production |
| ATE198119T1 (de) | 1994-09-01 | 2001-01-15 | Novo Nordisk As | Eine grundlegende proteinzusammensetzung zur abtötung oder inhibierung mikrobieller zellen |
| US6503881B2 (en) * | 1996-08-21 | 2003-01-07 | Micrologix Biotech Inc. | Compositions and methods for treating infections using cationic peptides alone or in combination with antibiotics |
| US20030113298A1 (en) | 1997-10-31 | 2003-06-19 | Vincent Fischetti | Use of bacterial phage associated lysing proteins for the prophylactic and therapeutic treatment of various illnesses |
| US5997862A (en) | 1997-10-31 | 1999-12-07 | New Horizons Diagnostics Corporation | Therapeutic treatment of group A streptococcal infections |
| US6428784B1 (en) | 1997-10-31 | 2002-08-06 | New Horizons Diagnostics Corp | Vaginal suppository for treating group B Streptococcus infection |
| US6288212B1 (en) | 1998-08-28 | 2001-09-11 | The University Of British Columbia | Anti-endotoxic, antimicrobial cationic peptides and methods of use therefor |
| US5993809A (en) * | 1998-11-18 | 1999-11-30 | Children's Hospital Medical Center | Lysozyme fusion proteins in infections |
| WO2001000855A1 (en) | 1999-06-23 | 2001-01-04 | Ppl Therapeutics (Scotland) Ltd. | Fusion proteins incorporating lysozyme |
| US7338936B2 (en) | 2000-11-28 | 2008-03-04 | House Ear Institute | Use of antimicrobial proteins and peptides for the treatment of otitis media and paranasal sinusitis |
| ATE443767T1 (de) | 2002-04-22 | 2009-10-15 | Dow Global Technologies Inc | Kostengünstige herstellung von peptiden |
| US7566447B2 (en) | 2003-05-15 | 2009-07-28 | Iogenetics, Llc | Biocides |
| BRPI0413833A (pt) | 2003-09-11 | 2006-10-24 | Novozymes As | célula hospedeira microbiana recombinante, construção de ácido nucleico, método para produzir uma enzima e/ou um agente antimicrobiano, produto de fusão, aditivo e composição de ração animal, animal não humano transgênico ou produtos ou elementos deste, usos do produto de fusão, da co-expressão de um agente antimicrobiano e uma enzima, e de um peptìdeo de proteção, e, método para identificar um peptìdeo de proteção |
| WO2005108563A2 (en) | 2004-04-19 | 2005-11-17 | University Of Chicago | Peptidoglycan-hydrolyzing protein encoded by bacteriophage n4 |
| US7572602B1 (en) | 2004-12-03 | 2009-08-11 | The United States Of America As Represented By The Secretary Of Agriculture | Nucleic acid encoding endolysin fusion protein |
| DE102005040347A1 (de) | 2005-08-25 | 2007-03-01 | Profos Ag | Verfahren und Mittel zur Anreicherung, Entfernung und zum Nachweis von Listerien |
| ATE470451T1 (de) | 2006-03-31 | 2010-06-15 | Univ St Andrews | Antimikrobielle zusammensetzungen mit einem kationischen peptid und glycylglycin- endopeptidase |
| DE102006061002A1 (de) | 2006-12-22 | 2008-06-26 | Profos Ag | Verfahren und Mittel zur Anreicherung, Entfernung und zum Nachweis von gram-positiven Bakterien |
| CN107129524B (zh) * | 2007-09-25 | 2023-11-21 | 田园温室气体研究有限公司 | 用于抑制微生物细胞的疫苗和疫苗组分 |
| JP2011504366A (ja) | 2007-11-26 | 2011-02-10 | プラント バイオサイエンス リミティド | エンドリシン活性を有する新規ポリペプチド及びその使用 |
| WO2010011960A2 (en) | 2008-07-24 | 2010-01-28 | The United State Of America, As Represented By The Secretary Of Agriculture | Triple acting antimicrobials that are refractory to resistance development |
| EP2157100A1 (en) * | 2008-08-19 | 2010-02-24 | Profos AG | Artificial peptidoglycan lysing enzymes and peptidoglycan binding proteins |
| GB0815484D0 (en) * | 2008-08-26 | 2008-10-01 | Univ Leuven Kath | Antibacterial agents |
| US8389679B2 (en) | 2009-02-05 | 2013-03-05 | The Regents Of The University Of California | Targeted antimicrobial moieties |
| DE102010014867A1 (de) * | 2009-04-17 | 2010-11-18 | Sms Siemag Ag | Verfahren zum Bereitstellen mindestens einer Arbeitswalze zum Walzen eines Walzguts |
| US8383102B2 (en) | 2009-05-21 | 2013-02-26 | The United States Of America As Represented By The Secretary Of Agriculture | Fusion of peptidoglycan hydrolase enzymes to a protein transduction domain allows eradication of both extracellular and intracellular gram positive pathogens |
| AU2010264659B2 (en) | 2009-06-26 | 2016-08-04 | Lysando Aktiengesellschaft | Antimicrobial agents |
| PL2445515T3 (pl) | 2009-06-26 | 2016-10-31 | Środki przeciwdrobnoustrojowe | |
| KR20120059576A (ko) | 2009-08-24 | 2012-06-08 | 뤼산도 홀딩 아게 | 신규한 엔도리신 ＯＢＰｇｐＬＹＳ |
| SG184836A1 (en) | 2010-04-27 | 2012-11-29 | Lysando Ag | Method of reducing biofilms |
| US9388400B2 (en) * | 2012-06-29 | 2016-07-12 | Lysando Ag | Composition for use in mycobacteria diagnosis |
-
2010
- 2010-06-28 AU AU2010264659A patent/AU2010264659B2/en active Active
- 2010-06-28 CN CN201080037886.7A patent/CN102482655B/zh active Active
- 2010-06-28 CA CA2765810A patent/CA2765810C/en active Active
- 2010-06-28 EP EP10727421.9A patent/EP2446028B1/en active Active
- 2010-06-28 JP JP2012516777A patent/JP6034188B2/ja active Active
- 2010-06-28 KR KR1020127002109A patent/KR101701890B1/ko active Active
- 2010-06-28 EP EP18165516.8A patent/EP3363896A1/en active Pending
- 2010-06-28 SG SG2012003745A patent/SG177704A1/en unknown
- 2010-06-28 BR BRPI1015203-2A patent/BRPI1015203B1/pt active IP Right Grant
- 2010-06-28 WO PCT/EP2010/059152 patent/WO2010149795A1/en not_active Ceased
- 2010-06-28 MX MX2011013453A patent/MX2011013453A/es active IP Right Grant
- 2010-06-28 US US13/380,329 patent/US20120195872A1/en not_active Abandoned
- 2010-06-28 EA EA201270082A patent/EA038542B1/ru unknown
-
2011
- 2011-12-21 IL IL217121A patent/IL217121B/en active IP Right Grant
-
2016
- 2016-07-01 JP JP2016131194A patent/JP2017018092A/ja active Pending
-
2019
- 2019-01-29 US US16/260,407 patent/US11136570B2/en not_active Expired - Fee Related
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