JP2012529906A5 - - Google Patents
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- Publication number
- JP2012529906A5 JP2012529906A5 JP2012515627A JP2012515627A JP2012529906A5 JP 2012529906 A5 JP2012529906 A5 JP 2012529906A5 JP 2012515627 A JP2012515627 A JP 2012515627A JP 2012515627 A JP2012515627 A JP 2012515627A JP 2012529906 A5 JP2012529906 A5 JP 2012529906A5
- Authority
- JP
- Japan
- Prior art keywords
- polypeptide
- chemokine
- seq
- polypeptide according
- binding
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US21349309P | 2009-06-15 | 2009-06-15 | |
| US61/213,493 | 2009-06-15 | ||
| PCT/IL2010/000473 WO2010146584A1 (en) | 2009-06-15 | 2010-06-15 | Novel chemokine binding polypeptides capable of inhibiting the course of autoimmunity, inflammation and cancer |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2012529906A JP2012529906A (ja) | 2012-11-29 |
| JP2012529906A5 true JP2012529906A5 (https=) | 2013-08-01 |
| JP5784010B2 JP5784010B2 (ja) | 2015-09-24 |
Family
ID=42933139
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012515627A Expired - Fee Related JP5784010B2 (ja) | 2009-06-15 | 2010-06-15 | 自己免疫性、炎症およびガンの経過を阻害し得る新規なケモカイン結合ポリペプチド |
Country Status (11)
| Country | Link |
|---|---|
| US (3) | US8685398B2 (https=) |
| EP (1) | EP2443137B1 (https=) |
| JP (1) | JP5784010B2 (https=) |
| KR (1) | KR20120046163A (https=) |
| CN (1) | CN102482324B (https=) |
| BR (1) | BRPI1009716A2 (https=) |
| CA (1) | CA2765188A1 (https=) |
| DK (1) | DK2443137T3 (https=) |
| HU (1) | HUE025294T2 (https=) |
| MX (1) | MX2011013457A (https=) |
| WO (1) | WO2010146584A1 (https=) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2003261723A1 (en) | 2002-08-27 | 2004-03-19 | Takeda Chemical Industries, Ltd. | Cxcr4 antagonist and use thereof |
| WO2008075371A2 (en) | 2006-12-21 | 2008-06-26 | Biokine Therapeutics Ltd. | T-140 peptide analogs having cxcr4 super-agonist activity for immunomodulation |
| BRPI1009663A2 (pt) | 2009-06-14 | 2016-10-11 | Biokine Therapeutics Ltd | "método para elevação dos níveis plaquetários em um indivíduo com essa necessidade, método de inibição de hemorragia em um indivíduo que a necessite e composição farmacêutica" |
| CN102482324B (zh) | 2009-06-15 | 2014-07-02 | 拜欧肯疗法有限公司 | 能够抑制自身免疫、炎症和癌症进程的新型趋化因子结合多肽 |
| US20130303460A1 (en) | 2011-01-10 | 2013-11-14 | Biokine Therapeutics Ltd. | Peptides and compositions for the treatment of neuroectodermal derived tumors and retinoblastoma |
| EP2841084B1 (en) | 2012-04-24 | 2018-05-30 | Biokine Therapeutics Ltd. | Cxcr4 antagonist peptide for use in the treatment of large cell lung cancer |
| CN106220711A (zh) * | 2014-09-05 | 2016-12-14 | 马恒标 | 大蒜中提取得到的抗肿瘤活性的多肽 |
| WO2016092544A1 (en) * | 2014-12-09 | 2016-06-16 | Biokine Therapeutics Ltd. | Compositions and methods for the treatment of ocular diseases |
| US10786547B2 (en) | 2015-07-16 | 2020-09-29 | Biokine Therapeutics Ltd. | Compositions, articles of manufacture and methods for treating cancer |
| EP3390378B1 (en) | 2015-12-17 | 2022-03-30 | AlonBio Ltd. | Small molecules against cancer |
| AU2016371466B2 (en) | 2015-12-17 | 2020-04-09 | Alonbio Ltd | Small Molecules for Inhibiting Chemokine Activity and/or Cancer Cells Growth |
| US20170204154A1 (en) | 2016-01-20 | 2017-07-20 | Delinia, Inc. | Molecules that selectively activate regulatory t cells for the treatment of autoimmune diseases |
| KR102033920B1 (ko) | 2016-02-23 | 2019-10-18 | 바이오라인알엑스 리미티드 | 급성 골수성 백혈병을 치료하는 방법 |
| PL3833786T3 (pl) * | 2018-08-10 | 2024-05-06 | Pantherna Therapeutics Gmbh | Konstrukt rekombinowanego kwasu nukleinowego |
| KR20200044321A (ko) * | 2018-10-19 | 2020-04-29 | 아이진 주식회사 | 염증성 질환의 예방 또는 치료용 약학적 조성물 |
| ES3014809T3 (en) | 2019-05-15 | 2025-04-25 | Alonbio Ltd | Small molecules for treating cancer, inhibiting chemokine activity and/or inducing cell death |
| KR102736939B1 (ko) * | 2021-09-30 | 2024-12-03 | (주)케어젠 | 항염증 활성을 갖는 펩타이드 및 이의 용도 |
| KR102609822B1 (ko) * | 2021-10-05 | 2023-12-06 | (주)케어젠 | 항염증 활성을 갖는 펩타이드와 이의 용도 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5116964A (en) * | 1989-02-23 | 1992-05-26 | Genentech, Inc. | Hybrid immunoglobulins |
| US5464764A (en) | 1989-08-22 | 1995-11-07 | University Of Utah Research Foundation | Positive-negative selection methods and vectors |
| UA48104C2 (uk) | 1991-10-04 | 2002-08-15 | Новартіс Аг | Фрагмент днк, який містить послідовність,що кодує інсектицидний протеїн, оптимізовану для кукурудзи,фрагмент днк, який забезпечує направлену бажану для серцевини стебла експресію зв'язаного з нею структурного гена в рослині, фрагмент днк, який забезпечує специфічну для пилку експресію зв`язаного з нею структурного гена в рослині, рекомбінантна молекула днк, спосіб одержання оптимізованої для кукурудзи кодуючої послідовності інсектицидного протеїну, спосіб захисту рослин кукурудзи щонайменше від однієї комахи-шкідника |
| US6096871A (en) | 1995-04-14 | 2000-08-01 | Genentech, Inc. | Polypeptides altered to contain an epitope from the Fc region of an IgG molecule for increased half-life |
| JP4046354B2 (ja) | 1996-03-18 | 2008-02-13 | ボード オブ リージェンツ，ザ ユニバーシティ オブ テキサス システム | 増大した半減期を有する免疫グロブリン様ドメイン |
| US6660843B1 (en) | 1998-10-23 | 2003-12-09 | Amgen Inc. | Modified peptides as therapeutic agents |
| US20030221931A1 (en) * | 2002-02-28 | 2003-12-04 | Steve Marsh | Sliding device |
| WO2007052173A2 (en) * | 2005-02-23 | 2007-05-10 | Endocube S.A.S. | Activity of thap-family chemokine-binding domains |
| EP1991578A2 (en) * | 2006-02-17 | 2008-11-19 | Rappaport Family Institute For Research in the Medical Sciences | Molecules and methods of using same for treating ccr5/ccr5 ligands associated diseases |
| CN102482324B (zh) | 2009-06-15 | 2014-07-02 | 拜欧肯疗法有限公司 | 能够抑制自身免疫、炎症和癌症进程的新型趋化因子结合多肽 |
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2010
- 2010-06-15 CN CN201080036127.9A patent/CN102482324B/zh not_active Expired - Fee Related
- 2010-06-15 EP EP10735337.7A patent/EP2443137B1/en not_active Not-in-force
- 2010-06-15 MX MX2011013457A patent/MX2011013457A/es active IP Right Grant
- 2010-06-15 BR BRPI1009716A patent/BRPI1009716A2/pt not_active IP Right Cessation
- 2010-06-15 WO PCT/IL2010/000473 patent/WO2010146584A1/en not_active Ceased
- 2010-06-15 JP JP2012515627A patent/JP5784010B2/ja not_active Expired - Fee Related
- 2010-06-15 KR KR1020127000920A patent/KR20120046163A/ko not_active Ceased
- 2010-06-15 HU HUE10735337A patent/HUE025294T2/en unknown
- 2010-06-15 US US13/378,063 patent/US8685398B2/en not_active Expired - Fee Related
- 2010-06-15 DK DK10735337.7T patent/DK2443137T3/en active
- 2010-06-15 CA CA2765188A patent/CA2765188A1/en not_active Abandoned
-
2014
- 2014-02-12 US US14/178,301 patent/US9493557B2/en not_active Expired - Fee Related
-
2016
- 2016-10-05 US US15/285,492 patent/US20170015708A1/en not_active Abandoned