JP2012526773A5 - - Google Patents

Download PDF

Info

Publication number
JP2012526773A5
JP2012526773A5 JP2012510296A JP2012510296A JP2012526773A5 JP 2012526773 A5 JP2012526773 A5 JP 2012526773A5 JP 2012510296 A JP2012510296 A JP 2012510296A JP 2012510296 A JP2012510296 A JP 2012510296A JP 2012526773 A5 JP2012526773 A5 JP 2012526773A5
Authority
JP
Japan
Prior art keywords
alkyl
heterocyclyl
halo
pharmaceutically acceptable
disease
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2012510296A
Other languages
English (en)
Japanese (ja)
Other versions
JP5654573B2 (ja
JP2012526773A (ja
JP5654573B6 (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/EP2010/056569 external-priority patent/WO2010130794A1/en
Publication of JP2012526773A publication Critical patent/JP2012526773A/ja
Publication of JP2012526773A5 publication Critical patent/JP2012526773A5/ja
Publication of JP5654573B2 publication Critical patent/JP5654573B2/ja
Application granted granted Critical
Publication of JP5654573B6 publication Critical patent/JP5654573B6/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2012510296A 2009-05-15 2010-05-12 ５−ピリジン−３−イル−１，３−ジヒドロ−インドール−２−オン誘導体およびアルドステロンシンターゼおよび／またはｃｙｐ１１ｂ１のモジュレーターとしてのそれらの使用 Expired - Fee Related JP5654573B6 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US17868409P 2009-05-15 2009-05-15
US61/178,684 2009-05-15
US32721810P 2010-04-23 2010-04-23
US61/327,218 2010-04-23
PCT/EP2010/056569 WO2010130794A1 (en) 2009-05-15 2010-05-12 5-pyridin-3-yl-1,3-dihydro-indol-2-on derivatives and their use as modulators of aldosterone synthase and/or cyp11b1

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2014235572A Division JP2015034187A (ja) 2009-05-15 2014-11-20 ５−ピリジン−３−イル−１，３−ジヒドロ−インドール−２−オン誘導体およびアルドステロンシンターゼおよび／またはｃｙｐ１１ｂ１のモジュレーターとしてのそれらの使用

Publications (4)

Publication Number Publication Date
JP2012526773A JP2012526773A (ja) 2012-11-01
JP2012526773A5 true JP2012526773A5 (https=) 2013-06-06
JP5654573B2 JP5654573B2 (ja) 2015-01-14
JP5654573B6 JP5654573B6 (ja) 2015-02-18

Family

ID=

Similar Documents

Publication Publication Date Title
CN106795099B (zh) 用于治疗高血压和心血管疾病的前药和组合物
EP2757884B1 (en) Pyrazolopyridyl compounds as aldosterone synthase inhibitors
JP2012526769A5 (https=)
EP3898654A2 (en) Inhibitors of fibroblast activation protein
US9518055B2 (en) Imidazopyridyl compounds as aldosterone synthase inhibitors
JP2016510769A5 (https=)
JP2015524476A5 (https=)
US9745282B2 (en) Indoline compounds as aldosterone synthase inhibitors
WO2012012478A1 (en) Aldosterone synthase inhibitors
JP2008222557A (ja) ピロロ［３，２−ｄ］ピリミジン誘導体及びこれを有効成分とする医薬組成物
RU2009110442A (ru) Конденсированные производные имидазола для лечения нарушений, опосредованных альдостеронсинтазой, и/или 11-бета-гидроксилазой, и/или ароматазой
MX2011004918A (es) Isoindoles sustituidos como inhibidores de enzima de escision de proteina precursora de amiloide del sitio beta y sus usos.
JP2011526917A5 (https=)
WO2011002409A1 (en) 5h-pyrrolo[3,4-£>]pyrazin-7-amine derivatives inhibitors of beta-secretase
Casimiro-Garcia et al. Design, synthesis, and evaluation of imidazo [4, 5-c] pyridin-4-one derivatives with dual activity at angiotensin II type 1 receptor and peroxisome proliferator-activated receptor-γ
JP2021501164A (ja) インドールアミン２，３−ジオキシゲナーゼのモジュレーター
JP2020504176A (ja) キナーゼを選択的に阻害する化合物及びその使用
TW200831079A (en) Angiotensin II receptor antagonists
EP3524250B1 (en) Pharmaceutical composition comprising a neutral endopeptidase (nep) inhibitor and an azilsartan ester derivative and use thereof for treating cardiovascular diseases
PT610698E (pt) Imidazo(4,5-b)piridinas e benzimidazoles substituidos como antagonistas de anguitensina ii
JP2012526773A5 (https=)
CN101195615B (zh) 咪唑-5-羧酸衍生物的盐、制备方法及其药物组合物
CN103827111B (zh) N-杂环取代酰胺衍生物
SG193477A1 (en) Novel phenylpyridine derivative and drug containing same
EP2934144B1 (en) Indazole compounds as aldosterone synthase inhibitors