JP2012524902A5 - - Google Patents
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- JP2012524902A5 JP2012524902A5 JP2012507255A JP2012507255A JP2012524902A5 JP 2012524902 A5 JP2012524902 A5 JP 2012524902A5 JP 2012507255 A JP2012507255 A JP 2012507255A JP 2012507255 A JP2012507255 A JP 2012507255A JP 2012524902 A5 JP2012524902 A5 JP 2012524902A5
- Authority
- JP
- Japan
- Prior art keywords
- mer unit
- seq
- identity
- heterodimer
- mer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US17197909P | 2009-04-23 | 2009-04-23 | |
| US61/171,979 | 2009-04-23 | ||
| PCT/US2010/030836 WO2010123720A1 (en) | 2009-04-23 | 2010-04-13 | Monomeric and dimeric forms of adiponectin receptor fragments and methods of use |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015209307A Division JP2016035470A (ja) | 2009-04-23 | 2015-10-23 | アディポネクチン受容体フラグメントの単量体及び二量体形態ならびに使用の方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2012524902A JP2012524902A (ja) | 2012-10-18 |
| JP2012524902A5 true JP2012524902A5 (enExample) | 2013-04-04 |
| JP5882196B2 JP5882196B2 (ja) | 2016-03-09 |
Family
ID=43011406
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012507255A Expired - Fee Related JP5882196B2 (ja) | 2009-04-23 | 2010-04-13 | アディポネクチン受容体フラグメントの単量体及び二量体形態ならびに使用の方法 |
| JP2015209307A Pending JP2016035470A (ja) | 2009-04-23 | 2015-10-23 | アディポネクチン受容体フラグメントの単量体及び二量体形態ならびに使用の方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015209307A Pending JP2016035470A (ja) | 2009-04-23 | 2015-10-23 | アディポネクチン受容体フラグメントの単量体及び二量体形態ならびに使用の方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (3) | US8865648B2 (enExample) |
| EP (2) | EP3444611A1 (enExample) |
| JP (2) | JP5882196B2 (enExample) |
| CN (1) | CN102388308B (enExample) |
| ES (1) | ES2693165T3 (enExample) |
| WO (1) | WO2010123720A1 (enExample) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8846315B2 (en) | 2008-08-12 | 2014-09-30 | Zinfandel Pharmaceuticals, Inc. | Disease risk factors and methods of use |
| KR20160127181A (ko) | 2008-08-12 | 2016-11-02 | 진판델 파마슈티컬스 인코포레이티드 | 질환 위험 인자의 식별 방법 |
| WO2010086867A2 (en) | 2009-02-02 | 2010-08-05 | Ramot At Tel Aviv University Ltd. | Peptides, pharmaceutical compositions comprising same and uses thereof |
| EP3444611A1 (en) | 2009-04-23 | 2019-02-20 | Siemens Healthcare Diagnostics Inc. | Monomeric and dimeric forms of adiponectin receptor fragments and methods of use |
| US8901074B2 (en) | 2010-08-04 | 2014-12-02 | Ramot At Tel-Aviv University | Methods of treating autoimmune diseases of the central nervous system (CNS) and neurodegenerative diseases |
| CN107362165A (zh) | 2011-01-10 | 2017-11-21 | 金帆德尔制药股份有限公司 | 用于治疗阿尔茨海默病的方法和药物产品 |
| US9291629B2 (en) | 2011-04-11 | 2016-03-22 | Siemens Healthcare Diagnostics Inc. | Adiponectin receptor C-terminal fragments (CTF)-immunoglobulin |
| IN2014CN03887A (enExample) * | 2011-10-27 | 2015-10-16 | Genmab As | |
| DE102015201100B4 (de) * | 2015-01-22 | 2018-05-17 | Friedrich-Alexander-Universität Erlangen-Nürnberg | Antivirale Mittel |
Family Cites Families (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| SE462454B (sv) | 1988-11-10 | 1990-06-25 | Pharmacia Ab | Maetyta foer anvaendning i biosensorer |
| US20020173474A1 (en) | 1993-02-12 | 2002-11-21 | President And Fellows Of Harvard College | Methods & materials involving dimerization-mediated regulation of biological events |
| PT700521E (pt) | 1993-05-28 | 2003-10-31 | Baylor College Medicine | Metodo e espectrometro de massa para dessorcao e ionizacao de analitos |
| SE9400088D0 (sv) | 1994-01-14 | 1994-01-14 | Kabi Pharmacia Ab | Bacterial receptor structures |
| NZ516848A (en) | 1997-06-20 | 2004-03-26 | Ciphergen Biosystems Inc | Retentate chromatography apparatus with applications in biology and medicine |
| JP3538711B2 (ja) | 1997-10-29 | 2004-06-14 | 大塚製薬株式会社 | 平滑筋増殖抑制組成物、動脈硬化症診断方法及びそのキット |
| EP1068356B8 (en) | 1998-04-03 | 2007-01-03 | Adnexus Therapeutics, Inc. | Addressable protein arrays |
| US6406921B1 (en) | 1998-07-14 | 2002-06-18 | Zyomyx, Incorporated | Protein arrays for high-throughput screening |
| AU4025300A (en) | 1999-03-24 | 2000-10-09 | Packard Bioscience Company | Continuous porous matrix arrays |
| US20040067490A1 (en) | 2001-09-07 | 2004-04-08 | Mei Zhong | Therapeutic polypeptides, nucleic acids encoding same, and methods of use |
| AU6906800A (en) | 1999-08-17 | 2001-03-13 | Incyte Genomics, Inc. | Membrane associated proteins |
| AU2001274888A1 (en) | 2000-05-19 | 2001-12-03 | Human Genome Sciences, Inc. | Nucleic acids, proteins, and antibodies |
| US20020102617A1 (en) | 2000-08-03 | 2002-08-01 | Macbeath Gavin | Protein microarrays |
| EP1379554A2 (en) | 2001-02-21 | 2004-01-14 | Curagen Corporation | Proteins, polynucleotides encoding them and methods of using the same |
| JP2004521930A (ja) | 2001-03-14 | 2004-07-22 | オクラホマ メディカル リサーチ ファウンデーション | アジポネクチンの投与により脂肪を減少させるための方法。 |
| US20030083261A1 (en) | 2001-04-30 | 2003-05-01 | Hongtao Yu | Class of 12mer peptides that inhibit the function of the mitotic check point protein Mad2 |
| DK1426764T3 (da) | 2001-08-17 | 2011-06-27 | Fujirebio Kk | Fremgangsmåde til diagnosticering eller monitorering af fejl i sukkermetabolisme |
| WO2004022596A1 (en) | 2002-09-05 | 2004-03-18 | Komed Co., Ltd. | Monoclonal antibody against adiponectin, preparation method and use thereof |
| US20030153013A1 (en) | 2002-11-07 | 2003-08-14 | Ruo-Pan Huang | Antibody-based protein array system |
| JP4347874B2 (ja) | 2002-12-29 | 2009-10-21 | 株式会社東京大学Tlo | アディポネクチン受容体及びそれをコードする遺伝子 |
| JP3955885B2 (ja) | 2002-12-29 | 2007-08-08 | 日産化学工業株式会社 | アディポネクチン受容体及びそれをコードする遺伝子 |
| EP1585987B1 (en) * | 2003-01-09 | 2009-08-19 | Beth Israel Deaconess Medical Center, Inc. | Use of adiponectin to diagnose malignancy |
| AU2004223553B2 (en) | 2003-03-24 | 2008-12-04 | Lsi Medience Corporation | Latex reagent for adiponectin analysis and method of adiponectin analysis |
| EP1718327B1 (en) | 2003-06-20 | 2015-01-07 | University of Florida | Biomarkers for differentiating between type 1 and type 2 diabetes |
| US7435808B2 (en) * | 2003-06-25 | 2008-10-14 | Bristol-Myers Squibb Company | Polynucleotides encoding novel adiponectin receptor variant, AdipoR2v2 |
| DE602004027746D1 (de) | 2003-09-27 | 2010-07-29 | Siemens Healthcare Diagnostics | Diagnostika und therapeutika für mit dem g-protein-gekoppelten rezeptor adipor1 (adipor1) assoziierte krankheiten |
| US20070053913A1 (en) | 2003-09-27 | 2007-03-08 | Bayer Healthcare Ag | Diagnostics and therapeutics for diseases associated with g-protein coupled receptor adipor2 (adipor2) |
| ES2329582T3 (es) | 2003-10-15 | 2009-11-27 | Sekisui Medical Co., Ltd. | Procedimiento de dosificacion selectiva de multimeros de adiponectina. |
| CA2545065C (en) | 2003-11-07 | 2012-07-17 | Merck & Co., Inc. | Method of identifying responders to treatment with insulin sensitizers |
| EP1733733A1 (en) * | 2004-03-04 | 2006-12-20 | Takashi Kadowaki | Regulator for adiponectin receptor expression |
| GB0426798D0 (en) | 2004-12-07 | 2005-01-12 | Emtelle Uk Ltd | Optical fibre tube and method of manufacturing same |
| US8093017B2 (en) * | 2005-12-07 | 2012-01-10 | Siemens Heathcare Diagnostics Inc. | Detection of soluble adiponectin receptor peptides and use in diagnostics and therapeutics |
| WO2009070350A1 (en) * | 2007-11-30 | 2009-06-04 | Siemens Healthcare Diagnostics Inc. | Adiponectin receptor fragments and methods of use |
| EP3444611A1 (en) | 2009-04-23 | 2019-02-20 | Siemens Healthcare Diagnostics Inc. | Monomeric and dimeric forms of adiponectin receptor fragments and methods of use |
-
2010
- 2010-04-13 EP EP18184946.4A patent/EP3444611A1/en not_active Withdrawn
- 2010-04-13 ES ES10767527.4T patent/ES2693165T3/es active Active
- 2010-04-13 EP EP10767527.4A patent/EP2422199B1/en not_active Not-in-force
- 2010-04-13 JP JP2012507255A patent/JP5882196B2/ja not_active Expired - Fee Related
- 2010-04-13 CN CN201080016065.5A patent/CN102388308B/zh not_active Expired - Fee Related
- 2010-04-13 WO PCT/US2010/030836 patent/WO2010123720A1/en not_active Ceased
- 2010-04-13 US US13/265,968 patent/US8865648B2/en active Active
-
2014
- 2014-10-20 US US14/518,749 patent/US20150038426A1/en not_active Abandoned
-
2015
- 2015-10-23 JP JP2015209307A patent/JP2016035470A/ja active Pending
-
2018
- 2018-08-09 US US16/100,176 patent/US20180346540A1/en not_active Abandoned
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