JP2012524902A5 - - Google Patents
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- Publication number
- JP2012524902A5 JP2012524902A5 JP2012507255A JP2012507255A JP2012524902A5 JP 2012524902 A5 JP2012524902 A5 JP 2012524902A5 JP 2012507255 A JP2012507255 A JP 2012507255A JP 2012507255 A JP2012507255 A JP 2012507255A JP 2012524902 A5 JP2012524902 A5 JP 2012524902A5
- Authority
- JP
- Japan
- Prior art keywords
- mer unit
- seq
- identity
- heterodimer
- mer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US17197909P | 2009-04-23 | 2009-04-23 | |
| US61/171,979 | 2009-04-23 | ||
| PCT/US2010/030836 WO2010123720A1 (en) | 2009-04-23 | 2010-04-13 | Monomeric and dimeric forms of adiponectin receptor fragments and methods of use |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015209307A Division JP2016035470A (ja) | 2009-04-23 | 2015-10-23 | アディポネクチン受容体フラグメントの単量体及び二量体形態ならびに使用の方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2012524902A JP2012524902A (ja) | 2012-10-18 |
| JP2012524902A5 true JP2012524902A5 (enExample) | 2013-04-04 |
| JP5882196B2 JP5882196B2 (ja) | 2016-03-09 |
Family
ID=43011406
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012507255A Expired - Fee Related JP5882196B2 (ja) | 2009-04-23 | 2010-04-13 | アディポネクチン受容体フラグメントの単量体及び二量体形態ならびに使用の方法 |
| JP2015209307A Pending JP2016035470A (ja) | 2009-04-23 | 2015-10-23 | アディポネクチン受容体フラグメントの単量体及び二量体形態ならびに使用の方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015209307A Pending JP2016035470A (ja) | 2009-04-23 | 2015-10-23 | アディポネクチン受容体フラグメントの単量体及び二量体形態ならびに使用の方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (3) | US8865648B2 (enExample) |
| EP (2) | EP2422199B1 (enExample) |
| JP (2) | JP5882196B2 (enExample) |
| CN (1) | CN102388308B (enExample) |
| ES (1) | ES2693165T3 (enExample) |
| WO (1) | WO2010123720A1 (enExample) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PE20110565A1 (es) | 2008-08-12 | 2011-09-02 | Zinfandel Pharmaceuticals Inc | Metodo de identificacion de factores de riesgo de la enfermedad |
| US8846315B2 (en) | 2008-08-12 | 2014-09-30 | Zinfandel Pharmaceuticals, Inc. | Disease risk factors and methods of use |
| EP2391377A2 (en) | 2009-02-02 | 2011-12-07 | Ramot at Tel-Aviv University Ltd. | Peptides, pharmaceutical compositions comprising same and uses thereof |
| EP2422199B1 (en) | 2009-04-23 | 2018-07-25 | Siemens Healthcare Diagnostics Inc. | Monomeric and dimeric forms of adiponectin receptor fragments and methods of use |
| US8901074B2 (en) | 2010-08-04 | 2014-12-02 | Ramot At Tel-Aviv University | Methods of treating autoimmune diseases of the central nervous system (CNS) and neurodegenerative diseases |
| EA201391017A1 (ru) | 2011-01-10 | 2014-04-30 | Зинфандел Фармасьютикалз, Инк. | Способы и готовые лекарственные формы для лечения болезни альцгеймера |
| US9291629B2 (en) | 2011-04-11 | 2016-03-22 | Siemens Healthcare Diagnostics Inc. | Adiponectin receptor C-terminal fragments (CTF)-immunoglobulin |
| DK2771364T3 (da) * | 2011-10-27 | 2019-08-19 | Genmab As | Fremstilling af heterodimere proteiner |
| DE102015201100B4 (de) * | 2015-01-22 | 2018-05-17 | Friedrich-Alexander-Universität Erlangen-Nürnberg | Antivirale Mittel |
Family Cites Families (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| SE462454B (sv) | 1988-11-10 | 1990-06-25 | Pharmacia Ab | Maetyta foer anvaendning i biosensorer |
| US20020173474A1 (en) | 1993-02-12 | 2002-11-21 | President And Fellows Of Harvard College | Methods & materials involving dimerization-mediated regulation of biological events |
| WO1994028418A1 (en) | 1993-05-28 | 1994-12-08 | Baylor College Of Medicine | Method and apparatus for desorption and ionization of analytes |
| SE9400088D0 (sv) | 1994-01-14 | 1994-01-14 | Kabi Pharmacia Ab | Bacterial receptor structures |
| NZ516848A (en) | 1997-06-20 | 2004-03-26 | Ciphergen Biosystems Inc | Retentate chromatography apparatus with applications in biology and medicine |
| EP1033134B8 (en) | 1997-10-29 | 2007-09-19 | Otsuka Pharmaceutical Co., Ltd. | Compositions inhibiting smooth muscle proliferation and method for the diagnosis of arteriosclerosis |
| EP1068356B8 (en) | 1998-04-03 | 2007-01-03 | Adnexus Therapeutics, Inc. | Addressable protein arrays |
| US6406921B1 (en) | 1998-07-14 | 2002-06-18 | Zyomyx, Incorporated | Protein arrays for high-throughput screening |
| WO2000056934A1 (en) | 1999-03-24 | 2000-09-28 | Packard Bioscience Company | Continuous porous matrix arrays |
| US20040067490A1 (en) | 2001-09-07 | 2004-04-08 | Mei Zhong | Therapeutic polypeptides, nucleic acids encoding same, and methods of use |
| CA2382015A1 (en) | 1999-08-17 | 2001-02-22 | Incyte Genomics, Inc. | Membrane associated proteins |
| AU2001274888A1 (en) | 2000-05-19 | 2001-12-03 | Human Genome Sciences, Inc. | Nucleic acids, proteins, and antibodies |
| US20020102617A1 (en) | 2000-08-03 | 2002-08-01 | Macbeath Gavin | Protein microarrays |
| CA2440219A1 (en) | 2001-02-21 | 2002-10-17 | Curagen Corporation | Proteins, polynucleotides encoding them and methods of using the same |
| CA2440144A1 (en) | 2001-03-14 | 2002-09-19 | Oklahoma Medical Research Foundation | Methods for reducing fat by administration of adiponectin |
| US20030083261A1 (en) | 2001-04-30 | 2003-05-01 | Hongtao Yu | Class of 12mer peptides that inhibit the function of the mitotic check point protein Mad2 |
| CA2459489C (en) | 2001-08-17 | 2010-02-02 | Rebio Gen, Inc. | Method for diagnosing or monitoring carbohydrate metabolism disorders |
| WO2004022596A1 (en) | 2002-09-05 | 2004-03-18 | Komed Co., Ltd. | Monoclonal antibody against adiponectin, preparation method and use thereof |
| US20030153013A1 (en) | 2002-11-07 | 2003-08-14 | Ruo-Pan Huang | Antibody-based protein array system |
| JP4347874B2 (ja) * | 2002-12-29 | 2009-10-21 | 株式会社東京大学Tlo | アディポネクチン受容体及びそれをコードする遺伝子 |
| DE60335216D1 (de) | 2002-12-29 | 2011-01-13 | Nissan Chemical Ind Ltd | Adiponektin-rezeptor und dafür kodierendes gen |
| DE602004022632D1 (de) * | 2003-01-09 | 2009-10-01 | Beth Israel Hospital | Verwendung von adiponectin zur diagnose von krebs |
| EP1607742B1 (en) | 2003-03-24 | 2011-11-23 | Mitsubishi Chemical Medience Corporation | Latex reagent for adiponectin analysis and method of adiponectin analysis |
| EP1718327B1 (en) | 2003-06-20 | 2015-01-07 | University of Florida | Biomarkers for differentiating between type 1 and type 2 diabetes |
| US7435808B2 (en) * | 2003-06-25 | 2008-10-14 | Bristol-Myers Squibb Company | Polynucleotides encoding novel adiponectin receptor variant, AdipoR2v2 |
| ES2347562T3 (es) * | 2003-09-27 | 2010-11-02 | Siemens Healthcare Diagnostics Inc. | Disagnosticos y terapias para enfermedades asociados con receptor emparejado de proteina g adipor1 (adipor1). |
| WO2005031345A2 (en) | 2003-09-27 | 2005-04-07 | Bayer Healthcare Ag | Diagnostics and therapeutics for diseases associated with g-protein coupled receptor adipor2 (adipor2) |
| DE602004022575D1 (de) | 2003-10-15 | 2009-09-24 | Sekisui Medical Co Ltd | Verfahren zum selektiven testen von adiponectinmultimeren |
| JP4397934B2 (ja) | 2003-11-07 | 2010-01-13 | メルク エンド カムパニー インコーポレーテッド | インスリン感作薬での処置に対する反応者を識別する方法 |
| EP1733733A1 (en) * | 2004-03-04 | 2006-12-20 | Takashi Kadowaki | Regulator for adiponectin receptor expression |
| GB0426798D0 (en) | 2004-12-07 | 2005-01-12 | Emtelle Uk Ltd | Optical fibre tube and method of manufacturing same |
| US8093017B2 (en) | 2005-12-07 | 2012-01-10 | Siemens Heathcare Diagnostics Inc. | Detection of soluble adiponectin receptor peptides and use in diagnostics and therapeutics |
| CA2707182C (en) * | 2007-11-30 | 2017-12-12 | Siemens Healthcare Diagnostics Inc. | Adiponectin receptor fragments and methods of use |
| EP2422199B1 (en) | 2009-04-23 | 2018-07-25 | Siemens Healthcare Diagnostics Inc. | Monomeric and dimeric forms of adiponectin receptor fragments and methods of use |
-
2010
- 2010-04-13 EP EP10767527.4A patent/EP2422199B1/en not_active Not-in-force
- 2010-04-13 JP JP2012507255A patent/JP5882196B2/ja not_active Expired - Fee Related
- 2010-04-13 CN CN201080016065.5A patent/CN102388308B/zh not_active Expired - Fee Related
- 2010-04-13 US US13/265,968 patent/US8865648B2/en active Active
- 2010-04-13 EP EP18184946.4A patent/EP3444611A1/en not_active Withdrawn
- 2010-04-13 ES ES10767527.4T patent/ES2693165T3/es active Active
- 2010-04-13 WO PCT/US2010/030836 patent/WO2010123720A1/en not_active Ceased
-
2014
- 2014-10-20 US US14/518,749 patent/US20150038426A1/en not_active Abandoned
-
2015
- 2015-10-23 JP JP2015209307A patent/JP2016035470A/ja active Pending
-
2018
- 2018-08-09 US US16/100,176 patent/US20180346540A1/en not_active Abandoned
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