JP2012524771A - 中性油を含む舌下用の医薬組成物 - Google Patents

中性油を含む舌下用の医薬組成物 Download PDF

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Publication number
JP2012524771A
JP2012524771A JP2012506583A JP2012506583A JP2012524771A JP 2012524771 A JP2012524771 A JP 2012524771A JP 2012506583 A JP2012506583 A JP 2012506583A JP 2012506583 A JP2012506583 A JP 2012506583A JP 2012524771 A JP2012524771 A JP 2012524771A
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JP
Japan
Prior art keywords
oil
eur
drug
miglyol
composition according
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2012506583A
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English (en)
Japanese (ja)
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JP2012524771A5 (enExample
Inventor
ブールス クライヴ
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
LondonPharma Ltd
Original Assignee
LondonPharma Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/GB2009/050416 external-priority patent/WO2010122276A1/en
Priority claimed from GB0906977A external-priority patent/GB2469792A/en
Application filed by LondonPharma Ltd filed Critical LondonPharma Ltd
Publication of JP2012524771A publication Critical patent/JP2012524771A/ja
Publication of JP2012524771A5 publication Critical patent/JP2012524771A5/ja
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/12—Aerosols; Foams
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Neurosurgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2012506583A 2009-04-23 2010-04-23 中性油を含む舌下用の医薬組成物 Pending JP2012524771A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
PCT/GB2009/050416 WO2010122276A1 (en) 2009-04-23 2009-04-23 Drug delivery
GB0906977A GB2469792A (en) 2009-04-23 2009-04-23 Oil-based pharmaceutical formulation for sublingual delivery
GBPCT/GB2009/050416 2009-04-23
GB0906977.4 2009-04-23
PCT/GB2010/050671 WO2010122355A1 (en) 2009-04-23 2010-04-23 Sublingual pharmaceutical composition comprising a neutral oil

Publications (2)

Publication Number Publication Date
JP2012524771A true JP2012524771A (ja) 2012-10-18
JP2012524771A5 JP2012524771A5 (enExample) 2013-05-09

Family

ID=42236683

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2012506583A Pending JP2012524771A (ja) 2009-04-23 2010-04-23 中性油を含む舌下用の医薬組成物

Country Status (15)

Country Link
US (1) US20120058158A1 (enExample)
EP (1) EP2421503A1 (enExample)
JP (1) JP2012524771A (enExample)
CN (1) CN102458358A (enExample)
AU (1) AU2010240653A1 (enExample)
BR (1) BRPI1013539A2 (enExample)
CA (1) CA2756879A1 (enExample)
IL (1) IL215454A (enExample)
MX (1) MX2011010835A (enExample)
MY (1) MY167918A (enExample)
NZ (1) NZ595467A (enExample)
RU (1) RU2011139638A (enExample)
SG (1) SG175160A1 (enExample)
WO (1) WO2010122355A1 (enExample)
ZA (1) ZA201107089B (enExample)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2019519487A (ja) * 2016-05-05 2019-07-11 アクエスティブ セラピューティクス インコーポレイテッド 送達増強エピネフリン組成物
JP2020535162A (ja) * 2017-09-27 2020-12-03 アクエスティブ セラピューティクス インコーポレイテッド 増強された送達のエピネフリン及びプロドラッグ組成物
US11273131B2 (en) 2016-05-05 2022-03-15 Aquestive Therapeutics, Inc. Pharmaceutical compositions with enhanced permeation
US12427121B2 (en) 2016-05-05 2025-09-30 Aquestive Therapeutics, Inc. Enhanced delivery epinephrine compositions
US12433850B2 (en) 2016-05-05 2025-10-07 Aquestive Therapeutics, Inc. Enhanced delivery epinephrine and prodrug compositions
US12465564B2 (en) 2021-10-25 2025-11-11 Aquestive Therapeutics, Inc. Oral and nasal compositions and methods of treatment

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8852638B2 (en) 2005-09-30 2014-10-07 Durect Corporation Sustained release small molecule drug formulation
US10512644B2 (en) 2007-03-12 2019-12-24 Inheris Pharmaceuticals, Inc. Oligomer-opioid agonist conjugates
US8173666B2 (en) 2007-03-12 2012-05-08 Nektar Therapeutics Oligomer-opioid agonist conjugates
EP2152315B1 (en) 2007-05-25 2016-01-06 Indivior UK Limited Sustained delivery formulations of risperidone compounds
GB0720967D0 (en) * 2007-10-25 2007-12-05 Protophama Ltd Anti-material pharmaceutical composition
GB2513060B (en) 2010-06-08 2015-01-07 Rb Pharmaceuticals Ltd Microparticle buprenorphine suspension
US9272044B2 (en) 2010-06-08 2016-03-01 Indivior Uk Limited Injectable flowable composition buprenorphine
US20130254139A1 (en) * 2012-03-21 2013-09-26 Xiaoguang Lei Systems and methods for building a universal intelligent assistant with learning capabilities
GB201404139D0 (en) 2014-03-10 2014-04-23 Rb Pharmaceuticals Ltd Sustained release buprenorphine solution formulations
US10376586B2 (en) * 2016-02-16 2019-08-13 Entourage Bioscience, LLC Method and compositions for solubilizing non-polar constituents
CA3048485C (en) * 2016-12-26 2022-07-19 Cellix Bio Private Limited Compositions and methods for the treatment of chronic pain
US12558305B2 (en) 2018-12-29 2026-02-24 Solventum Intellectual Properties Company Oral articles and methods of use
US12390488B2 (en) 2018-12-29 2025-08-19 Solventum Intellectual Properties Company Oral articles and methods of use
WO2021201680A1 (en) 2020-03-31 2021-10-07 Hasan Djohan Treatment of hyperinflammatory syndrome

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS63503304A (ja) * 1986-03-10 1988-12-02 ブルグハルト,クルト 医薬製剤およびその製造方法
JP2005512943A (ja) * 2001-02-14 2005-05-12 ジーダブリュー ファーマ リミテッド 医薬製剤
WO2009020666A1 (en) * 2007-08-06 2009-02-12 Insys Therapeutics Inc. Oral cannabinoid liquid formulations and methods of treatment
JP2012524772A (ja) * 2009-04-23 2012-10-18 ロンドンファーマ リミテッド ジヒドロアルテミシニンを含む舌下スプレー用製剤
JP5438018B2 (ja) * 2007-10-25 2014-03-12 プロトファーマ リミテッド 抗マラリア薬剤組成物

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5955098A (en) * 1996-04-12 1999-09-21 Flemington Pharmaceutical Corp. Buccal non polar spray or capsule
US20050281752A1 (en) * 1997-10-01 2005-12-22 Dugger Harry A Iii Buccal, polar and non-polar spray or capsule containing drugs for treating disorders of the central nervous system
SI1976521T1 (sl) * 2006-01-25 2015-06-30 Insys Therapeutics, Inc. Podjezično fentanilno pršilo

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS63503304A (ja) * 1986-03-10 1988-12-02 ブルグハルト,クルト 医薬製剤およびその製造方法
JP2005512943A (ja) * 2001-02-14 2005-05-12 ジーダブリュー ファーマ リミテッド 医薬製剤
WO2009020666A1 (en) * 2007-08-06 2009-02-12 Insys Therapeutics Inc. Oral cannabinoid liquid formulations and methods of treatment
JP5438018B2 (ja) * 2007-10-25 2014-03-12 プロトファーマ リミテッド 抗マラリア薬剤組成物
JP2012524772A (ja) * 2009-04-23 2012-10-18 ロンドンファーマ リミテッド ジヒドロアルテミシニンを含む舌下スプレー用製剤

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2019519487A (ja) * 2016-05-05 2019-07-11 アクエスティブ セラピューティクス インコーポレイテッド 送達増強エピネフリン組成物
US11191737B2 (en) 2016-05-05 2021-12-07 Aquestive Therapeutics, Inc. Enhanced delivery epinephrine compositions
US11273131B2 (en) 2016-05-05 2022-03-15 Aquestive Therapeutics, Inc. Pharmaceutical compositions with enhanced permeation
JP2023052143A (ja) * 2016-05-05 2023-04-11 アクエスティブ セラピューティクス インコーポレイテッド 送達増強エピネフリン組成物
US12023309B2 (en) 2016-05-05 2024-07-02 Aquestive Therapeutics, Inc. Enhanced delivery epinephrine compositions
JP7653218B2 (ja) 2016-05-05 2025-03-28 アクエスティブ セラピューティクス インコーポレイテッド 送達増強エピネフリン組成物
US12427121B2 (en) 2016-05-05 2025-09-30 Aquestive Therapeutics, Inc. Enhanced delivery epinephrine compositions
US12433850B2 (en) 2016-05-05 2025-10-07 Aquestive Therapeutics, Inc. Enhanced delivery epinephrine and prodrug compositions
JP2020535162A (ja) * 2017-09-27 2020-12-03 アクエスティブ セラピューティクス インコーポレイテッド 増強された送達のエピネフリン及びプロドラッグ組成物
US12465564B2 (en) 2021-10-25 2025-11-11 Aquestive Therapeutics, Inc. Oral and nasal compositions and methods of treatment

Also Published As

Publication number Publication date
CA2756879A1 (en) 2010-10-28
IL215454A (en) 2014-11-30
CN102458358A (zh) 2012-05-16
EP2421503A1 (en) 2012-02-29
ZA201107089B (en) 2012-12-27
MY167918A (en) 2018-09-27
RU2011139638A (ru) 2013-05-27
US20120058158A1 (en) 2012-03-08
MX2011010835A (es) 2012-05-08
IL215454A0 (en) 2011-12-29
SG175160A1 (en) 2011-11-28
BRPI1013539A2 (pt) 2016-04-12
WO2010122355A1 (en) 2010-10-28
NZ595467A (en) 2013-08-30
AU2010240653A1 (en) 2011-10-20

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