JP2012524771A - 中性油を含む舌下用の医薬組成物 - Google Patents

中性油を含む舌下用の医薬組成物 Download PDF

Info

Publication number
JP2012524771A
JP2012524771A JP2012506583A JP2012506583A JP2012524771A JP 2012524771 A JP2012524771 A JP 2012524771A JP 2012506583 A JP2012506583 A JP 2012506583A JP 2012506583 A JP2012506583 A JP 2012506583A JP 2012524771 A JP2012524771 A JP 2012524771A
Authority
JP
Japan
Prior art keywords
oil
eur
drug
miglyol
composition according
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2012506583A
Other languages
English (en)
Japanese (ja)
Other versions
JP2012524771A5 (enExample
Inventor
ブールス クライヴ
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
LondonPharma Ltd
Original Assignee
LondonPharma Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/GB2009/050416 external-priority patent/WO2010122276A1/en
Priority claimed from GB0906977A external-priority patent/GB2469792A/en
Application filed by LondonPharma Ltd filed Critical LondonPharma Ltd
Publication of JP2012524771A publication Critical patent/JP2012524771A/ja
Publication of JP2012524771A5 publication Critical patent/JP2012524771A5/ja
Pending legal-status Critical Current

Links

Images

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/12Aerosols; Foams
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2012506583A 2009-04-23 2010-04-23 中性油を含む舌下用の医薬組成物 Pending JP2012524771A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
PCT/GB2009/050416 WO2010122276A1 (en) 2009-04-23 2009-04-23 Drug delivery
GB0906977.4 2009-04-23
GB0906977A GB2469792A (en) 2009-04-23 2009-04-23 Oil-based pharmaceutical formulation for sublingual delivery
GBPCT/GB2009/050416 2009-04-23
PCT/GB2010/050671 WO2010122355A1 (en) 2009-04-23 2010-04-23 Sublingual pharmaceutical composition comprising a neutral oil

Publications (2)

Publication Number Publication Date
JP2012524771A true JP2012524771A (ja) 2012-10-18
JP2012524771A5 JP2012524771A5 (enExample) 2013-05-09

Family

ID=42236683

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2012506583A Pending JP2012524771A (ja) 2009-04-23 2010-04-23 中性油を含む舌下用の医薬組成物

Country Status (15)

Country Link
US (1) US20120058158A1 (enExample)
EP (1) EP2421503A1 (enExample)
JP (1) JP2012524771A (enExample)
CN (1) CN102458358A (enExample)
AU (1) AU2010240653A1 (enExample)
BR (1) BRPI1013539A2 (enExample)
CA (1) CA2756879A1 (enExample)
IL (1) IL215454A (enExample)
MX (1) MX2011010835A (enExample)
MY (1) MY167918A (enExample)
NZ (1) NZ595467A (enExample)
RU (1) RU2011139638A (enExample)
SG (1) SG175160A1 (enExample)
WO (1) WO2010122355A1 (enExample)
ZA (1) ZA201107089B (enExample)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2019519487A (ja) * 2016-05-05 2019-07-11 アクエスティブ セラピューティクス インコーポレイテッド 送達増強エピネフリン組成物
JP2020535162A (ja) * 2017-09-27 2020-12-03 アクエスティブ セラピューティクス インコーポレイテッド 増強された送達のエピネフリン及びプロドラッグ組成物
US11273131B2 (en) 2016-05-05 2022-03-15 Aquestive Therapeutics, Inc. Pharmaceutical compositions with enhanced permeation
US12427121B2 (en) 2016-05-05 2025-09-30 Aquestive Therapeutics, Inc. Enhanced delivery epinephrine compositions
US12433850B2 (en) 2016-05-05 2025-10-07 Aquestive Therapeutics, Inc. Enhanced delivery epinephrine and prodrug compositions
US12465564B2 (en) 2021-10-25 2025-11-11 Aquestive Therapeutics, Inc. Oral and nasal compositions and methods of treatment

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8852638B2 (en) 2005-09-30 2014-10-07 Durect Corporation Sustained release small molecule drug formulation
US10512644B2 (en) 2007-03-12 2019-12-24 Inheris Pharmaceuticals, Inc. Oligomer-opioid agonist conjugates
US8173666B2 (en) 2007-03-12 2012-05-08 Nektar Therapeutics Oligomer-opioid agonist conjugates
EP2907524A1 (en) 2007-05-25 2015-08-19 RB Pharmaceuticals Limited Sustained delivery formulations of risperidone compounds
GB0720967D0 (en) * 2007-10-25 2007-12-05 Protophama Ltd Anti-material pharmaceutical composition
GB2513060B (en) 2010-06-08 2015-01-07 Rb Pharmaceuticals Ltd Microparticle buprenorphine suspension
US9272044B2 (en) 2010-06-08 2016-03-01 Indivior Uk Limited Injectable flowable composition buprenorphine
US20130254139A1 (en) * 2012-03-21 2013-09-26 Xiaoguang Lei Systems and methods for building a universal intelligent assistant with learning capabilities
GB201404139D0 (en) 2014-03-10 2014-04-23 Rb Pharmaceuticals Ltd Sustained release buprenorphine solution formulations
US10376586B2 (en) * 2016-02-16 2019-08-13 Entourage Bioscience, LLC Method and compositions for solubilizing non-polar constituents
KR102442753B1 (ko) * 2016-12-26 2022-09-16 셀릭스 바이오 프라이빗 리미티드 만성 통증 치료를 위한 화합물
WO2020136620A1 (en) 2018-12-29 2020-07-02 3M Innovative Properties Company Oral articles and methods of use
PL4125843T3 (pl) 2020-03-31 2025-09-22 Remicine IP B.V. Leczenie ciężkiego zespołu zapalnego

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS63503304A (ja) * 1986-03-10 1988-12-02 ブルグハルト,クルト 医薬製剤およびその製造方法
JP2005512943A (ja) * 2001-02-14 2005-05-12 ジーダブリュー ファーマ リミテッド 医薬製剤
WO2009020666A1 (en) * 2007-08-06 2009-02-12 Insys Therapeutics Inc. Oral cannabinoid liquid formulations and methods of treatment
JP2012524772A (ja) * 2009-04-23 2012-10-18 ロンドンファーマ リミテッド ジヒドロアルテミシニンを含む舌下スプレー用製剤
JP5438018B2 (ja) * 2007-10-25 2014-03-12 プロトファーマ リミテッド 抗マラリア薬剤組成物

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5955098A (en) * 1996-04-12 1999-09-21 Flemington Pharmaceutical Corp. Buccal non polar spray or capsule
US20050281752A1 (en) * 1997-10-01 2005-12-22 Dugger Harry A Iii Buccal, polar and non-polar spray or capsule containing drugs for treating disorders of the central nervous system
US8486972B2 (en) * 2006-01-25 2013-07-16 Insys Therapeutics, Inc. Sublingual fentanyl spray

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS63503304A (ja) * 1986-03-10 1988-12-02 ブルグハルト,クルト 医薬製剤およびその製造方法
JP2005512943A (ja) * 2001-02-14 2005-05-12 ジーダブリュー ファーマ リミテッド 医薬製剤
WO2009020666A1 (en) * 2007-08-06 2009-02-12 Insys Therapeutics Inc. Oral cannabinoid liquid formulations and methods of treatment
JP5438018B2 (ja) * 2007-10-25 2014-03-12 プロトファーマ リミテッド 抗マラリア薬剤組成物
JP2012524772A (ja) * 2009-04-23 2012-10-18 ロンドンファーマ リミテッド ジヒドロアルテミシニンを含む舌下スプレー用製剤

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2019519487A (ja) * 2016-05-05 2019-07-11 アクエスティブ セラピューティクス インコーポレイテッド 送達増強エピネフリン組成物
US11191737B2 (en) 2016-05-05 2021-12-07 Aquestive Therapeutics, Inc. Enhanced delivery epinephrine compositions
US11273131B2 (en) 2016-05-05 2022-03-15 Aquestive Therapeutics, Inc. Pharmaceutical compositions with enhanced permeation
JP2023052143A (ja) * 2016-05-05 2023-04-11 アクエスティブ セラピューティクス インコーポレイテッド 送達増強エピネフリン組成物
US12023309B2 (en) 2016-05-05 2024-07-02 Aquestive Therapeutics, Inc. Enhanced delivery epinephrine compositions
JP7653218B2 (ja) 2016-05-05 2025-03-28 アクエスティブ セラピューティクス インコーポレイテッド 送達増強エピネフリン組成物
US12427121B2 (en) 2016-05-05 2025-09-30 Aquestive Therapeutics, Inc. Enhanced delivery epinephrine compositions
US12433850B2 (en) 2016-05-05 2025-10-07 Aquestive Therapeutics, Inc. Enhanced delivery epinephrine and prodrug compositions
JP2020535162A (ja) * 2017-09-27 2020-12-03 アクエスティブ セラピューティクス インコーポレイテッド 増強された送達のエピネフリン及びプロドラッグ組成物
US12465564B2 (en) 2021-10-25 2025-11-11 Aquestive Therapeutics, Inc. Oral and nasal compositions and methods of treatment

Also Published As

Publication number Publication date
EP2421503A1 (en) 2012-02-29
IL215454A0 (en) 2011-12-29
CA2756879A1 (en) 2010-10-28
CN102458358A (zh) 2012-05-16
IL215454A (en) 2014-11-30
MX2011010835A (es) 2012-05-08
MY167918A (en) 2018-09-27
AU2010240653A1 (en) 2011-10-20
ZA201107089B (en) 2012-12-27
WO2010122355A1 (en) 2010-10-28
US20120058158A1 (en) 2012-03-08
BRPI1013539A2 (pt) 2016-04-12
RU2011139638A (ru) 2013-05-27
NZ595467A (en) 2013-08-30
SG175160A1 (en) 2011-11-28

Similar Documents

Publication Publication Date Title
JP2012524771A (ja) 中性油を含む舌下用の医薬組成物
JP7617927B2 (ja) 口内溶解性フィルムおよび口内溶解性フィルムを製造し、使用する方法
CN103622950B (zh) 抗疟疾药物组合物
AU2012367017B2 (en) Medicament delivery technology
GB2469754A (en) Sub-lingual drug delivery system using a neutral oil
US20190142737A1 (en) Sublingual spray formulation comprising dihydroartemesinin
WO2010122276A1 (en) Drug delivery
HK1169939A (en) Sublingual pharmaceutical composition comprising a neutral oil
WO2010122275A1 (en) Pharmaceutical preparation
HK1190645B (en) Anti-malarial pharmaceutical composition
GB2469791A (en) Lipophilic compositions comprising an artemisinin derivative and their therapeutic uses

Legal Events

Date Code Title Description
A524 Written submission of copy of amendment under article 19 pct

Free format text: JAPANESE INTERMEDIATE CODE: A524

Effective date: 20130318

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20130318

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20140225

A977 Report on retrieval

Free format text: JAPANESE INTERMEDIATE CODE: A971007

Effective date: 20140228

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20140916