JP2012523221A5 - - Google Patents
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- Publication number
- JP2012523221A5 JP2012523221A5 JP2012503917A JP2012503917A JP2012523221A5 JP 2012523221 A5 JP2012523221 A5 JP 2012523221A5 JP 2012503917 A JP2012503917 A JP 2012503917A JP 2012503917 A JP2012503917 A JP 2012503917A JP 2012523221 A5 JP2012523221 A5 JP 2012523221A5
- Authority
- JP
- Japan
- Prior art keywords
- human monoclonal
- monoclonal antibody
- human
- seq
- light chain
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 102000039446 nucleic acids Human genes 0.000 claims 10
- 108020004707 nucleic acids Proteins 0.000 claims 10
- 150000007523 nucleic acids Chemical class 0.000 claims 10
- 125000003275 alpha amino acid group Chemical group 0.000 claims 5
- 239000002158 endotoxin Substances 0.000 claims 5
- 229920006008 lipopolysaccharide Polymers 0.000 claims 5
- 210000004027 cell Anatomy 0.000 claims 4
- 208000032536 Pseudomonas Infections Diseases 0.000 claims 3
- 210000004408 hybridoma Anatomy 0.000 claims 3
- 210000003719 b-lymphocyte Anatomy 0.000 claims 2
- 238000012258 culturing Methods 0.000 claims 2
- 230000002265 prevention Effects 0.000 claims 2
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 1
- 206010011409 Cross infection Diseases 0.000 claims 1
- 102000008300 Mutant Proteins Human genes 0.000 claims 1
- 108010021466 Mutant Proteins Proteins 0.000 claims 1
- 206010029803 Nosocomial infection Diseases 0.000 claims 1
- 206010035226 Plasma cell myeloma Diseases 0.000 claims 1
- 241000589517 Pseudomonas aeruginosa Species 0.000 claims 1
- 239000000427 antigen Substances 0.000 claims 1
- 102000036639 antigens Human genes 0.000 claims 1
- 108091007433 antigens Proteins 0.000 claims 1
- 230000021615 conjugation Effects 0.000 claims 1
- 238000003745 diagnosis Methods 0.000 claims 1
- 238000002405 diagnostic procedure Methods 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 229940079593 drug Drugs 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 239000012634 fragment Substances 0.000 claims 1
- 230000004927 fusion Effects 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
- 238000012986 modification Methods 0.000 claims 1
- 230000004048 modification Effects 0.000 claims 1
- 201000000050 myeloid neoplasm Diseases 0.000 claims 1
- 238000006384 oligomerization reaction Methods 0.000 claims 1
- 239000008194 pharmaceutical composition Substances 0.000 claims 1
- 230000028327 secretion Effects 0.000 claims 1
- 238000006467 substitution reaction Methods 0.000 claims 1
- 239000006228 supernatant Substances 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP09005245 | 2009-04-09 | ||
| EP09005245.7 | 2009-04-09 | ||
| PCT/EP2010/002158 WO2010115606A1 (en) | 2009-04-09 | 2010-04-06 | Human monoclonal antibody specific for lipopolysaccarides (lps) of serotype iats 01 of pseudomonas aeruginosa |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2012523221A JP2012523221A (ja) | 2012-10-04 |
| JP2012523221A5 true JP2012523221A5 (enExample) | 2013-05-23 |
Family
ID=40934847
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012503917A Withdrawn JP2012523221A (ja) | 2009-04-09 | 2010-04-06 | 緑膿菌（Ｐｓｅｕｄｏｍｏｎａｓａｅｒｕｇｉｎｏｓａ）のＩＡＴＳＯ１血清型のリポ多糖類（ＬＰＳ）に対して特異的なヒトモノクローナル抗体 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20120114657A1 (enExample) |
| EP (1) | EP2417157A1 (enExample) |
| JP (1) | JP2012523221A (enExample) |
| KR (1) | KR20120016086A (enExample) |
| CN (1) | CN102639562A (enExample) |
| BR (1) | BRPI1013427A2 (enExample) |
| CA (1) | CA2758081A1 (enExample) |
| IL (1) | IL215549A0 (enExample) |
| MX (1) | MX2011010634A (enExample) |
| WO (1) | WO2010115606A1 (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102858974A (zh) * | 2010-02-18 | 2013-01-02 | 明治制果药业株式会社 | 抗铜绿假单胞菌e血清型脂多糖的抗体 |
| CN103974975B (zh) * | 2011-06-10 | 2018-06-29 | 米迪缪尼有限公司 | 抗假单胞菌Psl结合分子及其用途 |
| JP6182152B2 (ja) | 2011-11-07 | 2017-08-16 | メディミューン，エルエルシー | 抗シュードモナス属（Ｐｓｅｕｄｏｍｏｎａｓ）ＰｓｌおよびＰｃｒＶ結合分子を用いた併用治療 |
| US11168131B2 (en) | 2015-11-10 | 2021-11-09 | Visterra, Inc. | Antibody molecule-drug conjugates and uses thereof |
| CA3049449A1 (en) | 2017-01-18 | 2018-07-26 | Visterra, Inc. | Antibody molecule-drug conjugates and uses thereof |
| AU2021248643A1 (en) | 2020-04-03 | 2022-10-27 | Visterra, Inc. | Antibody molecule-drug conjugates and uses thereof |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4834975A (en) | 1984-05-25 | 1989-05-30 | Genetics Corporation | Human monoclonal antibodies to serotypic lipopolysaccharide determinants on gram-negative bacteria and their production |
| US5955584A (en) * | 1986-03-31 | 1999-09-21 | Charter Ventures | Atherosclerotic plaque specific antigens, antibodies thereto, and uses thereof |
| ES2338105T3 (es) * | 2003-05-14 | 2010-05-04 | Kenta Biotech Ag | Anticuerpo monoclonal humano especifico para lipopolisacaridos (lps) de serotipo iats 06 pseudomonas aeruginosa. |
| EP1690875A1 (en) * | 2005-02-14 | 2006-08-16 | Kenta Biotech AG | Human monoclonal antibody specific for lipopolysaccharides (LPS) of the pseudomonas aeruginosa IATS O11 serotype |
-
2010
- 2010-04-06 KR KR1020117026384A patent/KR20120016086A/ko not_active Withdrawn
- 2010-04-06 EP EP10713132A patent/EP2417157A1/en not_active Ceased
- 2010-04-06 CA CA2758081A patent/CA2758081A1/en not_active Abandoned
- 2010-04-06 CN CN2010800256287A patent/CN102639562A/zh active Pending
- 2010-04-06 JP JP2012503917A patent/JP2012523221A/ja not_active Withdrawn
- 2010-04-06 WO PCT/EP2010/002158 patent/WO2010115606A1/en not_active Ceased
- 2010-04-06 BR BRPI1013427A patent/BRPI1013427A2/pt not_active IP Right Cessation
- 2010-04-06 MX MX2011010634A patent/MX2011010634A/es not_active Application Discontinuation
- 2010-04-06 US US13/262,791 patent/US20120114657A1/en not_active Abandoned
-
2011
- 2011-10-05 IL IL215549A patent/IL215549A0/en unknown
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