JP2012523009A5 - - Google Patents
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- JP2012523009A5 JP2012523009A5 JP2012504782A JP2012504782A JP2012523009A5 JP 2012523009 A5 JP2012523009 A5 JP 2012523009A5 JP 2012504782 A JP2012504782 A JP 2012504782A JP 2012504782 A JP2012504782 A JP 2012504782A JP 2012523009 A5 JP2012523009 A5 JP 2012523009A5
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- JP
- Japan
- Prior art keywords
- markers
- score
- mammal
- present
- disease score
- Prior art date
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- 238000000034 method Methods 0.000 claims description 43
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims description 32
- 239000012472 biological sample Substances 0.000 claims description 23
- 201000010099 disease Diseases 0.000 claims description 23
- 230000007383 nerve stimulation Effects 0.000 claims description 19
- 210000001186 vagus nerve Anatomy 0.000 claims description 19
- 241000124008 Mammalia Species 0.000 claims description 14
- 230000002503 metabolic effect Effects 0.000 claims description 10
- 208000035475 disorder Diseases 0.000 claims description 9
- 238000011282 treatment Methods 0.000 claims description 8
- 230000002757 inflammatory effect Effects 0.000 claims description 6
- 206010061218 Inflammation Diseases 0.000 claims description 4
- 230000004054 inflammatory process Effects 0.000 claims description 4
- 230000000508 neurotrophic effect Effects 0.000 claims description 4
- 210000004369 blood Anatomy 0.000 claims description 3
- 239000008280 blood Substances 0.000 claims description 3
- 210000001175 cerebrospinal fluid Anatomy 0.000 claims description 3
- 210000004698 lymphocyte Anatomy 0.000 claims description 3
- 210000002381 plasma Anatomy 0.000 claims description 3
- 210000002966 serum Anatomy 0.000 claims description 3
- 239000003550 marker Substances 0.000 claims description 2
- 230000004797 therapeutic response Effects 0.000 claims description 2
- 238000000338 in vitro Methods 0.000 claims 1
- 230000001225 therapeutic effect Effects 0.000 description 6
- 238000002560 therapeutic procedure Methods 0.000 description 6
- 239000000090 biomarker Substances 0.000 description 5
- 208000024714 major depressive disease Diseases 0.000 description 3
- 230000003542 behavioural effect Effects 0.000 description 2
- 238000009225 cognitive behavioral therapy Methods 0.000 description 2
- 238000003384 imaging method Methods 0.000 description 2
- 238000010320 meditation therapy Methods 0.000 description 2
- 238000001050 pharmacotherapy Methods 0.000 description 2
- 238000001671 psychotherapy Methods 0.000 description 2
- 230000003252 repetitive effect Effects 0.000 description 2
- 239000012491 analyte Substances 0.000 description 1
- 238000012544 monitoring process Methods 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US16698609P | 2009-04-06 | 2009-04-06 | |
| US61/166,986 | 2009-04-06 | ||
| PCT/US2010/030104 WO2010118035A2 (en) | 2009-04-06 | 2010-04-06 | Biomarkers for monitoring treatment of neuropsychiatric diseases |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2012523009A JP2012523009A (ja) | 2012-09-27 |
| JP2012523009A5 true JP2012523009A5 (enExample) | 2013-05-23 |
Family
ID=42936849
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012504782A Pending JP2012523009A (ja) | 2009-04-06 | 2010-04-06 | 精神神経疾患の治療をモニタリングするためのバイオマーカー |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20100280562A1 (enExample) |
| EP (1) | EP2417448A4 (enExample) |
| JP (1) | JP2012523009A (enExample) |
| CN (1) | CN102460153A (enExample) |
| CA (1) | CA2757659A1 (enExample) |
| WO (1) | WO2010118035A2 (enExample) |
Families Citing this family (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10912712B2 (en) | 2004-03-25 | 2021-02-09 | The Feinstein Institutes For Medical Research | Treatment of bleeding by non-invasive stimulation |
| US8868177B2 (en) * | 2009-03-20 | 2014-10-21 | ElectroCore, LLC | Non-invasive treatment of neurodegenerative diseases |
| US8158374B1 (en) | 2006-09-05 | 2012-04-17 | Ridge Diagnostics, Inc. | Quantitative diagnostic methods using multiple parameters |
| US9662490B2 (en) | 2008-03-31 | 2017-05-30 | The Feinstein Institute For Medical Research | Methods and systems for reducing inflammation by neuromodulation and administration of an anti-inflammatory drug |
| CA2740736A1 (en) * | 2008-10-15 | 2010-04-22 | Ridge Diagnostics, Inc. | Human biomarker hypermapping for depressive disorders |
| EP2356453A4 (en) | 2008-11-18 | 2012-08-15 | Ridge Diagnostics Inc | METABOLISM SYNDROME AND HPA AXIS BIOMARKERS FOR HEAVY DEPRESSION |
| CA2757518A1 (en) * | 2009-04-01 | 2010-10-07 | Ridge Diagnostics, Inc. | Biomarkers for monitoring treatment of neuropsychiatric diseases |
| US9211410B2 (en) | 2009-05-01 | 2015-12-15 | Setpoint Medical Corporation | Extremely low duty-cycle activation of the cholinergic anti-inflammatory pathway to treat chronic inflammation |
| EP2440284B1 (en) | 2009-06-09 | 2018-09-12 | Setpoint Medical Corporation | Nerve cuff with pocket for leadless stimulator |
| US11051744B2 (en) | 2009-11-17 | 2021-07-06 | Setpoint Medical Corporation | Closed-loop vagus nerve stimulation |
| US20150241447A1 (en) * | 2009-11-17 | 2015-08-27 | Ralph J. ZITNIK | Vagus nerve stimulation screening test |
| WO2011079309A2 (en) | 2009-12-23 | 2011-06-30 | Setpoint Medical Corporation | Neural stimulation devices and systems for treatment of chronic inflammation |
| CA2788315A1 (en) * | 2010-01-26 | 2011-08-04 | Ridge Diagnostics, Inc. | Multiple biomarker panels to stratify disease severity and monitor treatment of depression |
| WO2012081701A1 (ja) | 2010-12-16 | 2012-06-21 | 独立行政法人産業技術総合研究所 | 髄液型糖タンパク質の富化及び分離方法、並びにその方法を用いた中枢神経系疾患用マーカーの探索方法及び中枢神経系疾患用マーカー |
| US20120238837A1 (en) * | 2011-03-16 | 2012-09-20 | Searete Llc, A Limited Liability Corporation Of The State Of Delaware | System, devices, and methods for real-time monitoring of cerebrospinal fluid for markers of progressive conditions |
| US12172017B2 (en) | 2011-05-09 | 2024-12-24 | Setpoint Medical Corporation | Vagus nerve stimulation to treat neurodegenerative disorders |
| US9572983B2 (en) | 2012-03-26 | 2017-02-21 | Setpoint Medical Corporation | Devices and methods for modulation of bone erosion |
| US8737709B2 (en) * | 2012-04-30 | 2014-05-27 | General Electric Company | Systems and methods for performing correlation analysis on clinical outcome and characteristics of biological tissue |
| US11525834B2 (en) | 2013-07-11 | 2022-12-13 | University Of North Texas Health Science Center At Fort Worth | Blood-based screen for detecting neurological diseases in primary care settings |
| US11885816B2 (en) | 2013-11-26 | 2024-01-30 | University Of North Texas Health Science Center At Forth Worth | Personalized medicine approach for treating cognitive loss |
| WO2016004375A2 (en) * | 2014-07-02 | 2016-01-07 | Ridge Diagnostics, Inc. | Methods and materials for treating pain and depression |
| US11154712B2 (en) * | 2014-08-28 | 2021-10-26 | Medtronic Ardian Luxembourg S.A.R.L. | Methods for assessing efficacy of renal neuromodulation and associated systems and devices |
| US11311725B2 (en) | 2014-10-24 | 2022-04-26 | Setpoint Medical Corporation | Systems and methods for stimulating and/or monitoring loci in the brain to treat inflammation and to enhance vagus nerve stimulation |
| WO2016126807A1 (en) | 2015-02-03 | 2016-08-11 | Setpoint Medical Corporation | Apparatus and method for reminding, prompting, or alerting a patient with an implanted stimulator |
| US10596367B2 (en) | 2016-01-13 | 2020-03-24 | Setpoint Medical Corporation | Systems and methods for establishing a nerve block |
| WO2017127756A1 (en) | 2016-01-20 | 2017-07-27 | Setpoint Medical Corporation | Control of vagal stimulation |
| EP3405255A4 (en) | 2016-01-20 | 2019-10-16 | Setpoint Medical Corporation | IMPLANTABLE MICROSTIMULATORS AND INDUCTIVE CHARGING SYSTEMS |
| US11471681B2 (en) | 2016-01-20 | 2022-10-18 | Setpoint Medical Corporation | Batteryless implantable microstimulators |
| US10583304B2 (en) | 2016-01-25 | 2020-03-10 | Setpoint Medical Corporation | Implantable neurostimulator having power control and thermal regulation and methods of use |
| US11045126B2 (en) | 2016-10-28 | 2021-06-29 | Koa Health B.V. | System and a method for enabling responsive cognitive behavioral therapy |
| US11872371B2 (en) | 2017-04-20 | 2024-01-16 | The Feinstein Institutes For Medical Research | Systems and methods for real-time monitoring of physiological biomarkers through nerve signals and uses thereof |
| EP3668402B1 (en) | 2017-08-14 | 2024-07-31 | Setpoint Medical Corporation | Vagus nerve stimulation pre-screening test |
| KR102633621B1 (ko) | 2017-09-01 | 2024-02-05 | 벤 바이오사이언시스 코포레이션 | 진단 및 치료 모니터링용 바이오마커로서의 당펩티드의 식별 및 용도 |
| US12287324B2 (en) | 2018-01-18 | 2025-04-29 | University Of North Texas Health Science Center At Fort Worth | Companion diagnostics for NSAIDS and donepezil for treating specific subpopulations of patients suffering from Alzheimer's disease |
| US11260229B2 (en) | 2018-09-25 | 2022-03-01 | The Feinstein Institutes For Medical Research | Methods and apparatuses for reducing bleeding via coordinated trigeminal and vagal nerve stimulation |
| EP3952982B1 (en) | 2019-04-12 | 2024-03-27 | Setpoint Medical Corporation | Vagus nerve stimulation system to treat neurodegenerative disorders |
| CN111524596A (zh) * | 2020-04-07 | 2020-08-11 | 上海市精神卫生中心（上海市心理咨询培训中心） | 一种判断青少年双相障碍发病风险的方法 |
| US11938324B2 (en) | 2020-05-21 | 2024-03-26 | The Feinstein Institutes For Medical Research | Systems and methods for vagus nerve stimulation |
| US12444497B2 (en) | 2021-05-17 | 2025-10-14 | Setpoint Medical Corporation | Neurostimulation parameter authentication and expiration system for neurostimulation |
Family Cites Families (47)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5359681A (en) * | 1993-01-11 | 1994-10-25 | University Of Washington | Fiber optic sensor and methods and apparatus relating thereto |
| US5882203A (en) * | 1995-05-31 | 1999-03-16 | Correa; Elsa I. | Method of detecting depression |
| US5658802A (en) * | 1995-09-07 | 1997-08-19 | Microfab Technologies, Inc. | Method and apparatus for making miniaturized diagnostic arrays |
| US5804453A (en) * | 1996-02-09 | 1998-09-08 | Duan-Jun Chen | Fiber optic direct-sensing bioprobe using a phase-tracking approach |
| US20050123938A1 (en) * | 1999-01-06 | 2005-06-09 | Chondrogene Limited | Method for the detection of osteoarthritis related gene transcripts in blood |
| US20030032773A1 (en) * | 2000-02-24 | 2003-02-13 | Herath Herath Mudiyanselage Athula Chandrasiri | Proteins, genes and their use for diagnosis and treatment of bipolar affective disorder (BAD) and unipolar depression |
| US20040110938A1 (en) * | 2000-02-24 | 2004-06-10 | Parekh Rajesh Bhikhu | Proteins, genes and their use for diagnosis and treatment of schizophrenia |
| AU4345001A (en) * | 2000-03-09 | 2001-09-17 | Clinical Analysis Corp | Medical diagnostic system |
| US7094595B2 (en) * | 2000-10-30 | 2006-08-22 | Sru Biosystems, Inc. | Label-free high-throughput optical technique for detecting biomolecular interactions |
| US6905816B2 (en) * | 2000-11-27 | 2005-06-14 | Intelligent Medical Devices, Inc. | Clinically intelligent diagnostic devices and methods |
| ATE458199T1 (de) * | 2001-05-04 | 2010-03-15 | Biosite Inc | Diagnostische marker der akuten koronaren syndrome und ihre verwendungen |
| US6710877B2 (en) * | 2001-07-23 | 2004-03-23 | Corning Incorporated | Apparatus and methods for determining biomolecular interactions |
| US20050095646A1 (en) * | 2001-11-19 | 2005-05-05 | Sherman Michael I. | Method of using a non-antibody protein to detect and measure an analyte |
| US7136518B2 (en) * | 2003-04-18 | 2006-11-14 | Medispectra, Inc. | Methods and apparatus for displaying diagnostic data |
| US20040152107A1 (en) * | 2002-09-18 | 2004-08-05 | C. Anthony Altar | Gene signature of electroshock therapy and methods of use |
| KR20040032451A (ko) * | 2002-10-09 | 2004-04-17 | 삼성전자주식회사 | 생체신호 기반의 건강 관리 기능을 갖는 모바일 기기 및이를 이용한 건강 관리 방법 |
| US7490085B2 (en) * | 2002-12-18 | 2009-02-10 | Ge Medical Systems Global Technology Company, Llc | Computer-assisted data processing system and method incorporating automated learning |
| US7706871B2 (en) * | 2003-05-06 | 2010-04-27 | Nellcor Puritan Bennett Llc | System and method of prediction of response to neurological treatment using the electroencephalogram |
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| JP2005312435A (ja) * | 2004-03-29 | 2005-11-10 | Kazuhito Rokutan | うつ病の評価方法 |
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| EP1766398B1 (en) * | 2004-06-24 | 2011-01-05 | GE Healthcare Bio-Sciences AB | Method for detecting molecular surface interactions |
| US20060063199A1 (en) * | 2004-09-21 | 2006-03-23 | Elgebaly Salwa A | Diagnostic marker |
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| JP2007024822A (ja) * | 2005-07-21 | 2007-02-01 | Aska Pharmaceutical Co Ltd | 男性の更年期又はうつ病の鑑別方法 |
| CA2626490A1 (en) * | 2005-10-18 | 2007-04-26 | Cambridge Enterprise Limited | Methods and biomarkers for diagnosing and monitoring psychotic disorders such as schizophrenia |
| US20070161042A1 (en) * | 2006-01-11 | 2007-07-12 | Fortebio, Inc. | Methods for characterizing molecular interactions |
| EP2453236A3 (en) * | 2006-02-17 | 2012-08-22 | Atsuo Sekiyama | Biological load indicator and method of measuring biological load |
| US20080015465A1 (en) * | 2006-06-15 | 2008-01-17 | Scuderi Gaetano J | Methods for diagnosing and treating pain in the spinal cord |
| US7651836B2 (en) * | 2006-08-04 | 2010-01-26 | Hospital Santiago Apóstol | Methods for diagnosis and prognostic of psychiatric diseases |
| US8158374B1 (en) * | 2006-09-05 | 2012-04-17 | Ridge Diagnostics, Inc. | Quantitative diagnostic methods using multiple parameters |
| US20080199866A1 (en) * | 2006-10-10 | 2008-08-21 | The Board Of Trustees Of The Leland Stanford Junior University | Snp detection and other methods for characterizing and treating bipolar disorder and other ailments |
| WO2008099972A1 (ja) * | 2007-02-16 | 2008-08-21 | Shimadzu Corporation | 上皮性卵巣癌の組織型識別マーカー、及びそれを用いた組織型に基づく上皮性卵巣癌の罹患の識別法 |
| US20080281531A1 (en) * | 2007-03-15 | 2008-11-13 | Kazuhito Rokutan | Method for Diagnosing Depression |
| WO2009114627A2 (en) * | 2008-03-12 | 2009-09-17 | Ridge Diagnostics, Inc. | Inflammatory biomarkers for monitoring depression disorders |
| EP2329260A4 (en) * | 2008-03-04 | 2011-08-03 | Ridge Diagnostics Inc | DIAGNOSIS AND MONITORING OF DEPRESSIVE DISORDERS BASED ON A PLURALITY OF BIOMARKER PANELS |
| CA2740736A1 (en) * | 2008-10-15 | 2010-04-22 | Ridge Diagnostics, Inc. | Human biomarker hypermapping for depressive disorders |
| EP2356453A4 (en) * | 2008-11-18 | 2012-08-15 | Ridge Diagnostics Inc | METABOLISM SYNDROME AND HPA AXIS BIOMARKERS FOR HEAVY DEPRESSION |
| CA2757518A1 (en) * | 2009-04-01 | 2010-10-07 | Ridge Diagnostics, Inc. | Biomarkers for monitoring treatment of neuropsychiatric diseases |
| CA2788315A1 (en) * | 2010-01-26 | 2011-08-04 | Ridge Diagnostics, Inc. | Multiple biomarker panels to stratify disease severity and monitor treatment of depression |
| CN103370624A (zh) * | 2010-12-06 | 2013-10-23 | 里奇诊断学股份有限公司 | 监控神经精神疾病治疗的生物标记 |
-
2010
- 2010-04-06 WO PCT/US2010/030104 patent/WO2010118035A2/en not_active Ceased
- 2010-04-06 US US12/754,770 patent/US20100280562A1/en not_active Abandoned
- 2010-04-06 JP JP2012504782A patent/JP2012523009A/ja active Pending
- 2010-04-06 EP EP10762304A patent/EP2417448A4/en not_active Withdrawn
- 2010-04-06 CN CN2010800258668A patent/CN102460153A/zh active Pending
- 2010-04-06 CA CA2757659A patent/CA2757659A1/en not_active Abandoned
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