JP2012513412A5 - - Google Patents
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- Publication number
- JP2012513412A5 JP2012513412A5 JP2011542586A JP2011542586A JP2012513412A5 JP 2012513412 A5 JP2012513412 A5 JP 2012513412A5 JP 2011542586 A JP2011542586 A JP 2011542586A JP 2011542586 A JP2011542586 A JP 2011542586A JP 2012513412 A5 JP2012513412 A5 JP 2012513412A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- minutes
- less
- maltoside
- sumatriptan
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000203 mixture Substances 0.000 claims 23
- -1 Alkyl saccharide Chemical class 0.000 claims 10
- KQKPFRSPSRPDEB-UHFFFAOYSA-N sumatriptan Chemical compound CNS(=O)(=O)CC1=CC=C2NC=C(CCN(C)C)C2=C1 KQKPFRSPSRPDEB-UHFFFAOYSA-N 0.000 claims 10
- ZISSAWUMDACLOM-UHFFFAOYSA-N triptane Chemical class CC(C)C(C)(C)C ZISSAWUMDACLOM-UHFFFAOYSA-N 0.000 claims 10
- 229960003708 sumatriptan Drugs 0.000 claims 8
- 230000036470 plasma concentration Effects 0.000 claims 6
- KCXVZYZYPLLWCC-UHFFFAOYSA-N EDTA Chemical compound OC(=O)CN(CC(O)=O)CCN(CC(O)=O)CC(O)=O KCXVZYZYPLLWCC-UHFFFAOYSA-N 0.000 claims 3
- 239000008280 blood Substances 0.000 claims 3
- 210000004369 blood Anatomy 0.000 claims 3
- 150000001875 compounds Chemical class 0.000 claims 3
- UYEMNFYVTFDKRG-UHFFFAOYSA-N 2-[4,5-dihydroxy-2-(hydroxymethyl)-6-undecoxyoxan-3-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol Chemical group OC1C(O)C(OCCCCCCCCCCC)OC(CO)C1OC1C(O)C(O)C(O)C(CO)O1 UYEMNFYVTFDKRG-UHFFFAOYSA-N 0.000 claims 2
- 208000019695 Migraine disease Diseases 0.000 claims 2
- AYOPSBMGRBUJSJ-VQXBOQCVSA-N [(2s,3s,4s,5r)-3,4-dihydroxy-5-(hydroxymethyl)-2-[(2r,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxolan-2-yl]methyl dodecanoate Chemical compound O([C@@H]1[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O1)O)[C@]1(COC(=O)CCCCCCCCCCC)O[C@H](CO)[C@@H](O)[C@@H]1O AYOPSBMGRBUJSJ-VQXBOQCVSA-N 0.000 claims 2
- NLEBIOOXCVAHBD-QKMCSOCLSA-N dodecyl beta-D-maltoside Chemical compound O[C@@H]1[C@@H](O)[C@H](OCCCCCCCCCCCC)O[C@H](CO)[C@H]1O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 NLEBIOOXCVAHBD-QKMCSOCLSA-N 0.000 claims 2
- 229940090436 imitrex Drugs 0.000 claims 2
- 206010027599 migraine Diseases 0.000 claims 2
- 150000003839 salts Chemical class 0.000 claims 2
- WKEMJKQOLOHJLZ-UHFFFAOYSA-N Almogran Chemical compound C1=C2C(CCN(C)C)=CNC2=CC=C1CS(=O)(=O)N1CCCC1 WKEMJKQOLOHJLZ-UHFFFAOYSA-N 0.000 claims 1
- 101100228469 Caenorhabditis elegans exp-1 gene Proteins 0.000 claims 1
- 125000000217 alkyl group Chemical group 0.000 claims 1
- 229960002133 almotriptan Drugs 0.000 claims 1
- 229960002472 eletriptan Drugs 0.000 claims 1
- OTLDLQZJRFYOJR-LJQANCHMSA-N eletriptan Chemical compound CN1CCC[C@@H]1CC1=CN=C2[C]1C=C(CCS(=O)(=O)C=1C=CC=CC=1)C=C2 OTLDLQZJRFYOJR-LJQANCHMSA-N 0.000 claims 1
- 229960002284 frovatriptan Drugs 0.000 claims 1
- SIBNYOSJIXCDRI-SECBINFHSA-N frovatriptan Chemical compound C1=C(C(N)=O)[CH]C2=C(C[C@H](NC)CC3)C3=NC2=C1 SIBNYOSJIXCDRI-SECBINFHSA-N 0.000 claims 1
- 229930182470 glycoside Natural products 0.000 claims 1
- 238000002347 injection Methods 0.000 claims 1
- 239000007924 injection Substances 0.000 claims 1
- 239000000693 micelle Substances 0.000 claims 1
- 229960005254 naratriptan Drugs 0.000 claims 1
- UNHGSHHVDNGCFN-UHFFFAOYSA-N naratriptan Chemical compound C=12[CH]C(CCS(=O)(=O)NC)=CC=C2N=CC=1C1CCN(C)CC1 UNHGSHHVDNGCFN-UHFFFAOYSA-N 0.000 claims 1
- 239000007922 nasal spray Substances 0.000 claims 1
- 230000002459 sustained effect Effects 0.000 claims 1
- 229960001360 zolmitriptan Drugs 0.000 claims 1
- UTAZCRNOSWWEFR-ZDUSSCGKSA-N zolmitriptan Chemical compound C=1[C]2C(CCN(C)C)=CN=C2C=CC=1C[C@H]1COC(=O)N1 UTAZCRNOSWWEFR-ZDUSSCGKSA-N 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US12/341,696 US8268791B2 (en) | 2004-08-25 | 2008-12-22 | Alkylglycoside compositions for drug administration |
| US12/341,696 | 2008-12-22 | ||
| PCT/US2009/069326 WO2010075465A1 (en) | 2008-12-22 | 2009-12-22 | Compositions for drug administration |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015016547A Division JP2015108008A (ja) | 2008-12-22 | 2015-01-30 | 薬物投与のための組成物 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2012513412A JP2012513412A (ja) | 2012-06-14 |
| JP2012513412A5 true JP2012513412A5 (https=) | 2013-04-18 |
| JP5752048B2 JP5752048B2 (ja) | 2015-07-22 |
Family
ID=42288137
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011542586A Active JP5752048B2 (ja) | 2008-12-22 | 2009-12-22 | 薬物投与のための組成物 |
| JP2015016547A Pending JP2015108008A (ja) | 2008-12-22 | 2015-01-30 | 薬物投与のための組成物 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015016547A Pending JP2015108008A (ja) | 2008-12-22 | 2015-01-30 | 薬物投与のための組成物 |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US8268791B2 (https=) |
| EP (1) | EP2381773B1 (https=) |
| JP (2) | JP5752048B2 (https=) |
| KR (1) | KR101719008B1 (https=) |
| CN (1) | CN102325450B (https=) |
| AU (1) | AU2009329952B2 (https=) |
| BR (1) | BRPI0923403B1 (https=) |
| CA (1) | CA2748268C (https=) |
| DK (1) | DK2381773T3 (https=) |
| ES (1) | ES2667248T3 (https=) |
| MX (1) | MX356271B (https=) |
| NZ (1) | NZ593782A (https=) |
| RU (1) | RU2554814C2 (https=) |
| WO (1) | WO2010075465A1 (https=) |
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- 2008-12-22 US US12/341,696 patent/US8268791B2/en active Active
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- 2009-12-22 CN CN200980157305.0A patent/CN102325450B/zh active Active
- 2009-12-22 CA CA2748268A patent/CA2748268C/en active Active
- 2009-12-22 RU RU2011130526/15A patent/RU2554814C2/ru active
- 2009-12-22 WO PCT/US2009/069326 patent/WO2010075465A1/en not_active Ceased
- 2009-12-22 JP JP2011542586A patent/JP5752048B2/ja active Active
- 2009-12-22 KR KR1020117017361A patent/KR101719008B1/ko active Active
- 2009-12-22 EP EP09835809.6A patent/EP2381773B1/en active Active
- 2009-12-22 AU AU2009329952A patent/AU2009329952B2/en active Active
- 2009-12-22 BR BRPI0923403-9A patent/BRPI0923403B1/pt active IP Right Grant
- 2009-12-22 DK DK09835809.6T patent/DK2381773T3/en active
- 2009-12-22 NZ NZ593782A patent/NZ593782A/xx unknown
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