JP2012509321A5 - - Google Patents
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- Publication number
- JP2012509321A5 JP2012509321A5 JP2011537428A JP2011537428A JP2012509321A5 JP 2012509321 A5 JP2012509321 A5 JP 2012509321A5 JP 2011537428 A JP2011537428 A JP 2011537428A JP 2011537428 A JP2011537428 A JP 2011537428A JP 2012509321 A5 JP2012509321 A5 JP 2012509321A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- compound
- ray powder
- disintegrant
- powder diffraction
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US19988808P | 2008-11-21 | 2008-11-21 | |
| US61/199,888 | 2008-11-21 | ||
| US21039809P | 2009-03-17 | 2009-03-17 | |
| US61/210,398 | 2009-03-17 | ||
| PCT/US2009/006235 WO2010059239A2 (en) | 2008-11-21 | 2009-11-20 | Lactate salt of 4-(6-methoxy-7-(3-piperidin-1-yl-propoxy)quinazolin-4-yl]piperazine-1-carboxylic acid(4-isopropoxyphenyl)-amide and pharmaceutical compositions thereof for the treatment of cancer and other diseases or disorders |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014193355A Division JP2015017116A (ja) | 2008-11-21 | 2014-09-24 | 癌および他の疾患または障害の処置のための、４−［６−メトキシ−７−（３−ピペリジン−１−イル−プロポキシ）キナゾリン−４−イル］ピペラジン−１−カルボン酸（４−イソプロポキシフェニル）−アミドの乳酸塩およびその薬学的組成物 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2012509321A JP2012509321A (ja) | 2012-04-19 |
| JP2012509321A5 true JP2012509321A5 (https=) | 2012-12-27 |
Family
ID=41508688
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011537428A Pending JP2012509321A (ja) | 2008-11-21 | 2009-11-20 | 癌および他の疾患または障害の処置のための、４−［６−メトキシ−７−（３−ピペリジン−１−イル−プロポキシ）キナゾリン−４−イル］ピペラジン−１−カルボン酸（４−イソプロポキシフェニル）−アミドの乳酸塩およびその薬学的組成物 |
| JP2014193355A Pending JP2015017116A (ja) | 2008-11-21 | 2014-09-24 | 癌および他の疾患または障害の処置のための、４−［６−メトキシ−７−（３−ピペリジン−１−イル−プロポキシ）キナゾリン−４−イル］ピペラジン−１−カルボン酸（４−イソプロポキシフェニル）−アミドの乳酸塩およびその薬学的組成物 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014193355A Pending JP2015017116A (ja) | 2008-11-21 | 2014-09-24 | 癌および他の疾患または障害の処置のための、４−［６−メトキシ−７−（３−ピペリジン−１−イル−プロポキシ）キナゾリン−４−イル］ピペラジン−１−カルボン酸（４−イソプロポキシフェニル）−アミドの乳酸塩およびその薬学的組成物 |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US20100273808A1 (https=) |
| EP (1) | EP2370417A2 (https=) |
| JP (2) | JP2012509321A (https=) |
| WO (1) | WO2010059239A2 (https=) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2010223919B2 (en) | 2009-03-13 | 2016-03-31 | Les Laboratoires Servier | Methods and compositions for cell-proliferation-related disorders |
| RU2561132C2 (ru) | 2009-06-29 | 2015-08-20 | Аджиос Фармасьютикалз, Инк. | Производные хинолинсульфонамидов и их применение для модулирования пкм2 активности |
| EP3561077B1 (en) | 2009-10-21 | 2022-12-21 | Les Laboratoires Servier | Methods for cell-proliferation-related disorders |
| SG194697A1 (en) | 2011-05-03 | 2013-12-30 | Agios Pharmaceuticals Inc | Pyruvate kinase activators for use in therapy |
| CN102827170A (zh) | 2011-06-17 | 2012-12-19 | 安吉奥斯医药品有限公司 | 治疗活性组合物和它们的使用方法 |
| CN102827073A (zh) | 2011-06-17 | 2012-12-19 | 安吉奥斯医药品有限公司 | 治疗活性组合物和它们的使用方法 |
| US9474779B2 (en) | 2012-01-19 | 2016-10-25 | Agios Pharmaceuticals, Inc. | Therapeutically active compositions and their methods of use |
| WO2014062511A1 (en) | 2012-10-15 | 2014-04-24 | Agios Pharmaceuticals, Inc. | Therapeutic compounds and compositions |
| JP2014129238A (ja) * | 2012-12-28 | 2014-07-10 | Lion Corp | エトドラク含有固形製剤 |
| CN103058959B (zh) * | 2013-01-04 | 2014-09-10 | 华东理工大学 | 一种n-(2-(4-甲基哌嗪-1-基)-5-甲酰苯基)酰胺类化合物及其应用 |
| KR20140096571A (ko) * | 2013-01-28 | 2014-08-06 | 한미약품 주식회사 | 1-(4-(4-(3,4-디클로로-2-플루오로페닐아미노)-7-메톡시퀴나졸린-6-일옥시)피페리딘-1-일)프로프-2-엔-1-온의 제조방법 |
| CN105593215B (zh) | 2013-07-11 | 2019-01-15 | 安吉奥斯医药品有限公司 | 用于治疗癌症的作为idh2突变体抑制剂的2,4-或4,6-二氨基嘧啶化合物 |
| WO2015003355A2 (en) | 2013-07-11 | 2015-01-15 | Agios Pharmaceuticals, Inc. | Therapeutically active compounds and their methods of use |
| WO2015003360A2 (en) | 2013-07-11 | 2015-01-15 | Agios Pharmaceuticals, Inc. | Therapeutically active compounds and their methods of use |
| US9579324B2 (en) | 2013-07-11 | 2017-02-28 | Agios Pharmaceuticals, Inc | Therapeutically active compounds and their methods of use |
| US20150031627A1 (en) | 2013-07-25 | 2015-01-29 | Agios Pharmaceuticals, Inc | Therapeutically active compounds and their methods of use |
| BR122023021436A2 (pt) * | 2014-03-14 | 2023-12-12 | Les Laboratoires Servier | Formas cristalinas e composição farmacêutica de compostos terapeuticamente ativos |
| KR20240010105A (ko) * | 2014-03-14 | 2024-01-23 | 아지오스 파마슈티컬스 아이엔씨. | 치료적으로 활성인 화합물의 약제학적 조성물 |
| FI3307271T3 (fi) | 2015-06-11 | 2023-10-17 | Agios Pharmaceuticals Inc | Pyruvaattikinaasin aktivaattorien käyttämisen menetelmä |
| SG11201803088PA (en) | 2015-10-15 | 2018-05-30 | Agios Pharmaceuticals Inc | Combination therapy for treating malignancies |
| PT3362066T (pt) | 2015-10-15 | 2021-11-16 | Celgene Corp | Terapia de combinação para tratar malignidades |
| US10980788B2 (en) | 2018-06-08 | 2021-04-20 | Agios Pharmaceuticals, Inc. | Therapy for treating malignancies |
| CA3195702A1 (en) | 2020-10-13 | 2022-04-21 | Boehringer Ingelheim International Gmbh | Process of reworking |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU643280B2 (en) | 1990-05-25 | 1993-11-11 | Diamond Innovations, Inc. | Abrasive compact of cubic boron nitride and method of making same |
| US5101609A (en) | 1991-07-15 | 1992-04-07 | Eastman Kodak Company | Cigarette package inspection indexing wheel |
| JP2753911B2 (ja) * | 1991-12-06 | 1998-05-20 | キッセイ薬品工業株式会社 | Ｎ−ｔｅｒｔ−ブチル−１−メチル−３，３−ジフェニルプロピルアミン塩酸塩の結晶多形およびその製造方法 |
| JPH05230044A (ja) * | 1992-02-21 | 1993-09-07 | Hoechst Japan Ltd | ピレタニドの新規な結晶多形 |
| JP3532988B2 (ja) * | 1995-02-22 | 2004-05-31 | アベンティス ファーマ株式会社 | ピレタニドの新規な結晶多形およびその製造方法 |
| NZ330571A (en) * | 1996-10-01 | 1999-10-28 | Kyowa Hakko Kogyo Kk | Nitrogenous heterocyclic compounds that may contain sulphur or oxygen |
| JP3011904B2 (ja) * | 1997-06-10 | 2000-02-21 | 明久 井上 | 金属ガラスの製造方法および装置 |
| DE69943144D1 (de) * | 1998-03-31 | 2011-03-03 | Kyowa Hakko Kirin Co Ltd | Stickstoffenthaltende heterocyclische verbindungen |
| ES2354039T3 (es) * | 2000-08-18 | 2011-03-09 | Millennium Pharmaceuticals, Inc. | Derivados de n-aril-{4-[7-(alcoxi)quinazolin-4-il]piperazinil}carboxamida como inhibidores de pdgfr. |
| AU8544901A (en) * | 2000-08-18 | 2002-03-04 | Cor Therapeutics Inc | Quinazoline derivatives as kinase inhibitors |
| WO2002016361A2 (en) * | 2000-08-18 | 2002-02-28 | Cor Therapeutics, Inc. | Nitrogenous heterocyclic compounds |
| DE60144284D1 (de) * | 2000-11-01 | 2011-05-05 | Millennium Pharm Inc | Stickstoffhaltige heterozyklische verbindungen und verfahren zu deren herstellung |
| US20040259881A1 (en) * | 2001-02-02 | 2004-12-23 | Anjali Pandey | Nitrogenous heterocyclic compounds |
| EP1490362A2 (en) * | 2001-03-08 | 2004-12-29 | Millennium Pharmaceuticals, Inc. | (homo)piperazine substituted quinolines for inhibiting the phosphorylation of kinases |
| US7058169B2 (en) * | 2003-08-27 | 2006-06-06 | D.B. Zwirn Finance, Llc | Skill based chat function in a communication system |
| US7456189B2 (en) * | 2003-09-30 | 2008-11-25 | Boehringer Ingelheim International Gmbh | Bicyclic heterocycles, medicaments containing these compounds, their use and processes for their preparation |
| CN102225926A (zh) * | 2003-11-07 | 2011-10-26 | 诺华疫苗和诊断公司 | 具有改进药物特性的喹啉酮类化合物的药学上可接受的盐 |
| US20060063735A1 (en) * | 2004-09-17 | 2006-03-23 | Supergen, Inc. | Salts of 5-azacytidine |
| JP2008519055A (ja) * | 2004-11-08 | 2008-06-05 | シャイア エルエルシー | ミルタザピンと興奮剤複合物の併用投与の相乗効果 |
| EP1833819A1 (en) * | 2004-12-30 | 2007-09-19 | Astex Therapeutics Limited | Pyrazole compounds that modulate the activity of cdk, gsk and aurora kinases |
| WO2006072832A1 (en) * | 2005-01-07 | 2006-07-13 | Pfizer Products Inc. | Fast-disintegrating dosage forms of 5,8,14-triazatetracyclo[10.3.1.02,11.04,9]-hexadeca-2(11),3,5,7,9-pentaene |
| JP2009502804A (ja) * | 2005-07-20 | 2009-01-29 | ミレニアム・ファーマシューティカルズ・インコーポレイテッド | ４−［６−メトキシ−７−（３−ピペリジン−１−イル−プロポキシ）キナゾリン−４−イル］ピペラジン−１−カルボン酸（４−イソプロポキシフェニル）−アミドの新規な結晶形 |
| DE102005042784A1 (de) | 2005-07-26 | 2007-02-01 | Bosch Rexroth Aktiengesellschaft | Ventilanordnung und Kühlvorrichtung |
-
2009
- 2009-11-20 EP EP09771435A patent/EP2370417A2/en not_active Withdrawn
- 2009-11-20 JP JP2011537428A patent/JP2012509321A/ja active Pending
- 2009-11-20 US US12/622,617 patent/US20100273808A1/en not_active Abandoned
- 2009-11-20 WO PCT/US2009/006235 patent/WO2010059239A2/en not_active Ceased
-
2014
- 2014-09-24 JP JP2014193355A patent/JP2015017116A/ja active Pending
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